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Research uncovers DNA looping damage tied to HPV cancer

Research uncovers DNA looping damage tied to HPV cancer
2014-04-16
It's long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers at The Ohio State University have determined a new way that HPV might spark cancer development – by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates. Worldwide, HPV causes about 610,000 cases of cancer annually, accounting for about five percent of all cancer cases and virtually all cases of cervical cancer. Yet, the mechanisms behind the process aren't yet completely understood. This study, recently ...

New type of barcode could make counterfeiters' lives more difficult

2014-04-16
Counterfeiters, beware! Scientists are reporting the development of a new type of inexpensive barcode that, when added to documents or currency, could foil attempts at making forgeries. Although the tags are easy for researchers to make, they still require ingredients you can't exactly find at the local hardware store. Their report appears in the Journal of the American Chemical Society. Xiaogang Liu and colleagues explain that scientists have used fluorescent and DNA-based barcodes, or tags of known composition and sequence, in attempts to develop tests for cancer and ...

A greener source of polyester -- cork trees

2014-04-16
On the scale of earth-friendly materials, you'd be hard pressed to find two that are farther apart than polyester (not at all) and cork (very). In an unexpected twist, however, scientists are figuring out how to extract a natural, waterproof, antibacterial version of the first material from the latter. Their new technique, which could have applications in medical devices, appears in the ACS journal Biomacromolecules. Cristina Silva Pereira and colleagues explain that polyesters are ubiquitous in modern life, and not just as a practical fabric for clothing. Their durability ...

Local homicide rate increases cause more elementary students to fail school

2014-04-16
WASHINGTON, DC, April 16, 2014 — A new study finds that an increase in a municipality's homicide rate causes more elementary school students in that community to fail a grade than would do so if the rate remained stable. "This finding is a source of concern because exposure to environmental violence is highly prevalent in contemporary societies and is unequally distributed along socioeconomic lines," said study co-author Florencia Torche, an associate professor of sociology at New York University. "To the extent that children living in poverty are more likely to experience ...

Making radiation-proof materials for electronics, power plants

2014-04-16
The 2011 Fukushima nuclear disaster made the dangers of radiation all too real. To avoid similar tragedies in the future, scientists are working to develop new radiation-proof materials for nuclear power plants, as well as for less obvious applications such as medical devices and airplanes. An article in Chemical & Engineering News (C&EN), the American Chemical Society's weekly news magazine, explores the latest developments. Jyllian Kemsley, a senior editor at C&EN, points out that radiation can cause a range of problems from temperature misreadings in electronic devices ...

U of T study finds toddlers 'surprisingly sophisticated' at understanding unfamiliar accents

2014-04-16
TORONTO, ON -- A new University of Toronto study has found that by two years of age, children are remarkably good at comprehending speakers who talk with accents the toddlers have never heard before. Even more striking, say researchers, children as young as 15 months who have difficulty comprehending accents they've never heard before can quickly learn to understand accented speech after hearing the speaker for a short time. "Fifteen-month-olds typically say relatively few words, yet they can learn to understand someone with a completely unfamiliar accent," says Elizabeth ...

Survey: Percent of uninsured Texans has declined since September 2013

2014-04-16
HOUSTON – (April 16, 2014) – The percentage of uninsured adults ages 18 to 64 in Texas declined from 24.8 to 23.5 between September 2013 and March 2014, according to a report released today by Rice University's Baker Institute for Public Policy and the Episcopal Health Foundation. The decrease in uninsured appears to be attributable to an increase in employer-sponsored health insurance. The report also found that during this period approximately 746,000 Texans purchased health insurance through the Affordable Care Act's Health Insurance Marketplace, of which 178,000 ...

HIV+ women respond well to HPV vaccine

2014-04-16
PROVIDENCE, R.I. [Brown University] — HIV-positive women respond well to a vaccine against the human papillomavirus (HPV), even when their immune system is struggling, according to newly published results of an international clinical trial. The study's findings counter doubts about whether the vaccine would be helpful, said the Brown University medical professor who led the study. Instead, the data support the World Health Organization's recommendation to vaccinate women with HIV. HPV causes cervical and other cancers. The commonly used HPV vaccine Gardasil had not been ...

First metritis vaccine protects dairy cows

2014-04-16
ITHACA, N.Y. – Cornell scientists have created the first vaccines that can prevent metritis, one of the most common cattle diseases. The infection not only harms animals and farmers' profits, but also drives more systemic antibiotic use on dairy farms than any other disease. The new vaccines prevent metritis infection of the uterus from taking hold and reduce symptoms when it does, a prospect that could save the United States billions of dollars a year and help curb the growing epidemic of antibiotic resistance. The research was published in the journal PLOS One. Metritis ...

At the origin of cell division

At the origin of cell division
2014-04-16
Droplets of filamentous material enclosed in a lipid membrane: these are the models of a "simplified" cell used by the SISSA physicists Luca Giomi and Antonio DeSimone, who simulated the spontaneous emergence of cell motility and division - that is, features of living material - in inanimate "objects". The research is one of the cover stories of the April 10th online issue of the journal Physical Review Letters. Giomi and DeSimone's artificial cells are in fact computer models that mimic some of the physical properties of the materials making up the inner content and ...

EU must take urgent action on invasive species

2014-04-16
The EU must take urgent action to halt the spread of invasive species that are threatening native plants and animals across Europe, according to a scientist from Queen's University Belfast. The threats posed by these species cost an estimated €12 billion each year across Europe. Professor Jaimie Dick, from the Institute for Global Food Security at Queen's School of Biological Sciences, is calling on the EU to commit long-term investment in a European-wide strategy to manage the problem. Invasive species are considered to be among the major threats to native biodiversity ...

Expect changes in appetite, taste of food after weight loss surgery

2014-04-16
Changes in appetite, taste and smell are par for the course for people who have undergone Roux-en-Y gastric bypass surgery during which one's stomach is made smaller and small intestines shortened. These sensory changes are not all negative, and could lead to more weight loss among patients, says Lisa Graham, lead author of a study by researchers from Leicester Royal Infirmary in the UK. Their findings, published in Springer's journal Obesity Surgery showed that after gastric bypass surgery, patients frequently report sensory changes. Graham and her colleagues say their ...

Fish exposed to antidepressants exhibit altered behavioral changes

2014-04-16
Amsterdam, April 16, 2014 - Fish exposed to the antidepressant Fluoxetine, an active ingredient in prescription drugs such as Prozac, exhibited a range of altered mating behaviours, repetitive behaviour and aggression towards female fish, according to new research published on in the latest special issue of Aquatic Toxicology: Antidepressants in the Aquatic Environment. The authors of the study set up a series of experiments exposing a freshwater fish (Fathead Minnow) to a range of Prozac concentrations. Following exposure for 4 weeks the authors observed and recorded ...

Study: The trials of the Cherokee were reflected in their skulls

2014-04-16
Researchers from North Carolina State University and the University of Tennessee have found that environmental stressors – from the Trail of Tears to the Civil War – led to significant changes in the shape of skulls in the eastern and western bands of the Cherokee people. The findings highlight the role of environmental factors in shaping our physical characteristics. "We wanted to look at these historically important events and further our understanding of the tangible human impacts they had on the Cherokee people," says Dr. Ann Ross, a professor of anthropology at NC ...

Progress in understanding immune response in severe schistosomiasis

Progress in understanding immune response in severe schistosomiasis
2014-04-16
BOSTON (April 16, 2014) —Researchers at the Sackler School of Graduate Biomedical Sciences at Tufts and Tufts University School of Medicine (TUSM) have uncovered a mechanism that may help explain the severe forms of schistosomiasis, or snail fever, which is caused by schistosome worms and is one of the most prevalent parasitic diseases in the world. The study in mice, published online in The Journal of Immunology, may also offer targets for intervention and amelioration of the disease. Schistosomiasis makes some people very sick whereas others tolerate it relatively well, ...

Floating nuclear plants could ride out tsunamis

2014-04-16
CAMBRIDGE, Mass-- When an earthquake and tsunami struck the Fukushima Daiichi nuclear plant complex in 2011, neither the quake nor the inundation caused the ensuing contamination. Rather, it was the aftereffects — specifically, the lack of cooling for the reactor cores, due to a shutdown of all power at the station — that caused most of the harm. A new design for nuclear plants built on floating platforms, modeled after those used for offshore oil drilling, could help avoid such consequences in the future. Such floating plants would be designed to be automatically cooled ...

Bristol academics invited to speak at major 5G summit

2014-04-16
For more than 20 years academics from the University of Bristol have played a key role in the development of wireless communications. In particular, they have contributed to the development of today's Wi-Fi and cellular standards. Two Bristol engineers, who are leaders in this field, have been invited to a meeting of technology leaders to discuss the future of wireless communications. The first "Brooklyn 5G Summit" will be held next week [April 23-25] in New York, USA. Andrew Nix, Professor of Wireless Communication Systems and Mark Beach, Professor of Radio Systems ...

Researchers question emergency water treatment guidelines

2014-04-16
The Environmental Protection Agency's (EPA's) recommendations for treating water after a natural disaster or other emergencies call for more chlorine bleach than is necessary to kill disease-causing pathogens and are often impractical to carry out, a new study has found. The authors of the report, which appears in the ACS journal Environmental Science & Technology, suggest that the agency review and revise its guidelines. Daniele Lantagne, who was at the Centers for Disease Control and Prevention (CDC) at the time of the study and is now at Tufts University, and colleagues ...

Relieving electric vehicle range anxiety with improved batteries

Relieving electric vehicle range anxiety with improved batteries
2014-04-16
RICHLAND, Wash. – Electric vehicles could travel farther and more renewable energy could be stored with lithium-sulfur batteries that use a unique powdery nanomaterial. Researchers added the powder, a kind of nanomaterial called a metal organic framework, to the battery's cathode to capture problematic polysulfides that usually cause lithium-sulfur batteries to fail after a few charges. A paper describing the material and its performance was published online April 4 in the American Chemical Society journal Nano Letters. "Lithium-sulfur batteries have the potential to ...

Breakthrough points to new drugs from nature

2014-04-16
Researchers at Griffith University's Eskitis Institute have developed a new technique for discovering natural compounds which could form the basis of novel therapeutic drugs. The corresponding author, Professor Ronald Quinn AM said testing the new process on a marine sponge had delivered not only confirmation that the system is effective, but also a potential lead in the fight against Parkinson's disease. "We have found a new screening method which allows us to identify novel molecules drawn from nature to test for biological activity," Professor Quinn said. "As it ...

Global scientific team 'visualizes' a new crystallization process

Global scientific team visualizes a new crystallization process
2014-04-16
VIDEO: This is a high speed video of the crystal ribbons forming as the solution is spread using a squeegee like technique. Click here for more information. Sometimes engineers invent something before they fully comprehend why it works. To understand the "why," they must often create new tools and techniques in a virtuous cycle that improves the original invention while also advancing basic scientific knowledge. Such was the case about two years ago, when Stanford engineers ...

Researchers propose network-based evaluation tool to assess relief operations feasibility

Researchers propose network-based evaluation tool to assess relief operations feasibility
2014-04-16
The United Nations Office for Disaster Risk Reduction reported that disasters have affected around 2.9 billion people worldwide from 2000-2012— killing more than a million, and damaging around 1.7 trillion US dollars in estimates. Moreover, natural disasters and their damages have been documented to occur with increasing intensity. Given the staggering numbers, effective disaster preparedness and relief response plans is compelling, especially considering the fact that natural disasters are usually unpredictable and damage cannot be avoided. Implementing a speedy and ...

Medieval slave trade routes in Eastern Europe extended from Finland and the Baltic Countries to Asia

2014-04-16
The routes of slave trade in Eastern Europe in the medieval and pre-modern period extended all the way to the Caspian Sea and Central Asia. A recent study completed at the University of Eastern Finland suggests that persons captured during raids into areas which today constitute parts of Finland, the Russian Karelia and the Baltic Countries ended up being sold on these remote trade routes. There was a particular demand for blonde girls and boys who were seen as exotic luxury items, and it was financially beneficial to transport them to the far-away markets. The study by ...

Study provides new insight into how toddlers learn verbs

2014-04-16
Parents can help toddlers' language skills by showing them a variety of examples of different actions, according to new research from the University of Liverpool. Previous research has shown that verbs pose particular difficulties to toddlers as they refer to actions rather than objects, and actions are often different each time a child sees them. To find out more about this area of child language, University psychologists asked a group of toddlers to watch one of two short videos. They then examined whether watching a cartoon star repeat the same action, compared ...

Potential use of Google Glass in surgical settings

2014-04-16
Oxford, UK, April 15, 2014 – An article recently published in the International Journal of Surgery shows the potential applications for Google Glass in the surgical setting, particularly in relation to training. Personal portable information technology is advancing at a breathtaking speed. Google has recently introduced Glass, a device that is worn like conventional glasses, but that combines a computerized central processing unit, touchpad, display screen, high-definition camera, microphone, bone-conduction transducer, and wireless connectivity. The authors of the ...
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