New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) suggests that Sweden—the country already thought to have the second highest prevalence of type 1 diabetes in the world—could have 2-3 times more adolescents and young adults with type 1 diabetes than previously estimated. The research is by Dr Araz Rawshani, Swedish National Diabetes Register, Gothenburg, Sweden, and colleagues. Current estimates in Sweden are based on the Diabetes Incidence Study in Sweden (DISS), which has been around since 1983. The DISS is one ...

A third of intensive care patients develop depression that typically manifests as physical, or somatic, symptoms such as weakness, appetite change, and fatigue, rather than psychological symptoms, according to one of the largest studies to investigate the mental health and functional outcomes of survivors of critical care, published in The Lancet Respiratory Medicine. The study suggests that intensive care unit (ICU) survivors could be three times more likely to experience depression than the general population, and that depression is four times more common than post-traumatic ...

SAN DIEGO, CA (April 6, 2014)—Researchers from Fox Chase Cancer Center have shown that NEDD9, a scaffolding protein responsible for regulating signaling pathways in the cell, promotes the growth and spread of epithelial ovarian cancer. Previous studies have demonstrated the protein's importance in tumor invasion and spread of some lymphomas and many solid tumor types, including melanoma, neuroblastoma, and breast cancer, but its role in gynecological cancers has been poorly understood. The new data, to be presented on Sunday, April 6 at the AACR Annual Meeting 2014, ...

Your body's cells have two major interconnected energy sources: the lipid metabolism and the glucose metabolism. Most cancers feed themselves by metabolizing glucose, and thus can be seen in Positron Emission Topography (PET) scans that detect radiolabeled glucose. However, prostate cancers tend to use the lipid metabolism route and so cannot be imaged in this way effectively. A University of Colorado Cancer Center study being presented today at the American Association for Cancer Research (AACR) Annual Meeting 2014 describes a novel method to "manipulate the lipid metabolism ...

SAN DIEGO, CA (April 6, 2014)—Tumor cells are picky about where they live. In the wrong environment, they fail to reach their potential. But put those same cells on the right bit of real estate, and they grow like mad. Researchers at Fox Chase Cancer Center found renal cancer cells planted in a supportive environment proliferate with the help of an enzyme usually only seen in the brain. The enzyme, a specific isoform of a rather common kinase, may eventually become a target for cancer therapy as kinases constitute reasonably targetable enzymes, said Edna Cukierman, PhD, ...

LA JOLLA, CA—April 6, 2014—A study led by scientists at The Scripps Research Institute (TSRI) has helped solve a long-standing mystery about the sense of touch. The "gentle touch" sensations that convey the stroke of a finger, the fine texture of something grasped and the light pressure of a breeze on the skin are brought to us by nerves that often terminate against special skin cells called Merkel cells. These skin cells' role in touch sensation has long been debated in the scientific community. The new study, however, suggests a dual-sensor system involving the Merkel ...

VIDEO: This animation shows the basic process of sequencing amino acids in a nanopore, using the technique of recognition tunneling. Click here for more information. Some three billion base pairs make up the human genome—the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease. Nevertheless, the primary actors in virtually all ...

BOSTON, MA (April 6, 2014) -- Researchers studying a rare, always fatal brain tumor in children have found several molecular alterations that drive the cancer, according to a new study from scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and McGill University. The findings identify potential new targets for drug treatments. The new research could help physicians choose targeted agents with a better chance of combating pediatric high-grade astrocytomas, which are extremely difficult to treat with radiation and surgery. The tumors have resisted ...

For the first time, a field test has demonstrated that elevated levels of carbon dioxide inhibit plants' assimilation of nitrate into proteins, indicating that the nutritional quality of food crops is at risk as climate change intensifies. Findings from this wheat field-test study, led by a UC Davis plant scientist, will be reported online April 6 in the journal Nature Climate Change. "Food quality is declining under the rising levels of atmospheric carbon dioxide that we are experiencing," said lead author Arnold Bloom, a professor in the Department of Plant Sciences. "Several ...

PULLMAN, Wash.—Researchers led by a Washington State University biologist have found that arid areas, among the biggest ecosystems on the planet, take up an unexpectedly large amount of carbon as levels of carbon dioxide increase in the atmosphere. The findings give scientists a better handle on the earth's carbon budget—how much carbon remains in the atmosphere as CO2, contributing to global warming, and how much gets stored in the land or ocean in other carbon-containing forms. "It has pointed out the importance of these arid ecosystems," said R. Dave Evans, a WSU professor ...

The transfer, via a viral vector, of a normal copy of the gene deficient in patients, allowed to fully and very rapidly cure the heart disease in mice. These findings are published in Nature Medicine on 6 April, 2014. Friedreich's ataxia is a severe, rare hereditary disorder which combines progressive neuro-degeneration, impaired heart function and an increased risk of diabetes. The condition affects one in every 50,000 birth. There is currently no effective treatment for this disease. In most cases, Friedreich's ataxia starts in adolescence with impaired balance and ...

The visibility of smoking in city streets has for the first time anywhere been mapped, in new research from the University of Otago, Wellington, New Zealand. The research found that up to 116 smokers outside bars/cafés could be seen from any one location in the outdoor public areas of downtown Wellington (e.g. on a footpath). Of 2600 people observed in the outdoor areas of bars and cafés, 16% were smoking, with a higher proportion than this in evenings. Data from observations across the downtown area were mapped by the researchers, producing a record of the street ...

STANFORD, Calif. — A blood sample could one day be enough to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient's body and responses to treatment. Previous versions of the approach, which relies on monitoring levels of tumor DNA circulating in the blood, have required cumbersome and time-consuming steps to customize it to each patient or have not been sufficiently sensitive. Now, researchers at the Stanford University School of Medicine have devised a way to quickly bring the technique to the clinic. Their approach, which should be broadly ...

VIDEO: This video shows the motion of nanoparticles in neighboring layers of the superlattice as pressure is applied. Click here for more information. A combined computational and experimental study of self-assembled silver-based structures known as superlattices has revealed an unusual and unexpected behavior: arrays of gear-like molecular-scale machines that rotate in unison when pressure is applied to them. Computational and experimental studies show that the superlattice ...

At St. Paul's Cathedral in London, a section of the dome called the Whispering Gallery makes a whisper audible from the other side of the dome as a result of the way sound waves travel around the curved surface. Researchers at Washington University in St. Louis have used the same phenomenon to build an optical device that may lead to new and more powerful computers that run faster and cooler. Lan Yang, PhD, associate professor of electrical and systems engineering, and her collaborators have developed an essential component of these new computers that would run on light. ...

VIDEO: This video shows a Merkel cell responding to touch. Click here for more information. NEW YORK, NY, April 6, 2014 — In a study published in the April 6 online edition of the journal Nature, a team of Columbia University Medical Center researchers led by Ellen Lumpkin, PhD, associate professor of somatosensory biology, solve an age-old mystery of touch: how cells just beneath the skin surface enable us to feel fine details and textures. Touch is the last frontier of ...

Shadow musician, Catman Cohen, proposes to create a new CD that will be a radical departure from his past efforts. "Knocking Bones & Kissing Shadows" will aim to be the exemplar of what is considered desirable in contemporary music. Catman's 5th CD will be a raw and passionate sonic dance...sexual to the nth degree....mindless to the max....and contrived in service of a 24 hour round-the-clock orgiastic party. The music will pound and throb, the airhead lyrics will extol nothing other the celebration of genital satisfaction, buying expensive stuff, getting high, and ...

WellBiz Brands, Inc., parent company to Elements Massage and Fitness Together , announced the appointment of Abby Lee as the company's new Chief Marketing Officer. Lee has a strong background in brand marketing and advertising, most recently serving as the Vice President of Brand Marketing and Sponsorships at RE/MAX where she managed and implemented media and marketing campaigns in more than 100 U.S. markets and coordinated national and local sponsorships. At WellBiz, Lee will be responsible for overseeing marketing initiatives that support new client trial, boost membership ...

The 6th Annual Loveland Art Studio Tour (LAST) has issued a call for artists for its 2014 event. Applications are available here via CallForEntry at https://www.callforentry.org/festivals_unique_info.php?ID=1880&sortby=fair_name&apply=yes. When: Applications accepted through May 10. Artists notified May 20. Event Dates: October 11 & 12 and October 18 & 19, 2014, 10:00 a.m. to 5:00 p.m. daily. LAST seeks passionate, unique, interesting artists who have an individual style. Because one of the event's goals is to educate the community about art, artists ...

With spring time comes prom season, and with that comes shopping for the perfect dress and shoes to go with it. Buying a prom dress can really put a dent in the wallet, and adding on the expense of evening shoes can make the event very costly. However, at iLoveSexy, an online retailer for lingerie, clubwear, and shoes, finding the right shoes for that night does not have to break the bank. Shopping for prom shoes is all about finding a matching color and deciding whether to go with a simple or statement shoe. For a simple shoe option that can be worn even after prom, ...

From April 23 - May 21, kids up to age fourteen are invited to unleash their imagination and enter an original charm design for a chance to have it produced and sold in the new co-branded contest collection launching at the start of 2015. Visit http://www.shopcharm-it.com or http://www.crayola.com for an Official Entry Form and list of participating specialty retailers nationwide. CHARM IT! will host an exclusive Design-A-Charm event at The Crayola Experience in Easton, PA on Saturday, May 3rd. Mark your calendar and attend this colorful day full of art and smiles! ...

These spacious suites are built with anodized aluminum frames and HDPE plastic panels to be attractive and durable for any number of temporary or permanent uses, such as: peak season boarding, day care breaks, intake kennels, high density suites, grooming drying kennels, or veterinary rehabilitation space. Multiple configurations are possible: single, double high or back-to-back. Set up or take down in just minutes per suite with no tools required. Whether stacked as convenient storage carts or set up as high density suites, Express Kennels help you get the most out of ...

McDonald Automotive group has announced that as of April 1st, 2014 their company will be known as McDonald Automotive. McDonald Automotive is a family business. The word "group" has a corporate connotation that the McDonald family does not feel accurately represents their business. McDonald Automotive has also updated their current business logo to better suit the automotive market today. The emblem is still recognizable as the McDonald Automotive brand as a blue oval with a white road crossing through it however has a new age look to it. The McDonald family has been ...

Snap! Event Productions today announced Amber Jenkins has been named a partner in the firm effective immediately. Jenkins, a specialist in video, media and live event productions, has been a member of the Snap! team for ten years. As partner, she will assume a strategic leadership role while continuing to provide event production expertise to clients. "Amber works tirelessly to be sure every Snap! client has a successful event and a positive experience with our firm," said Terri Sue Wensinger, founder and president of Snap! Event Productions. "Her unique creative energy, ...

Gardere Wynne Sewell LLP is pleased to announce that Firm Attorneys Scott D. Ellis, Jason R. Fulmer, Jessica Glatzer Mason, Audrey Momanaee and James C. Scott have been admitted as partners effective April 1, 2014. "These promotions reflect great individual success, while reinforcing their commitment to the Gardere team and to our clients," says Gardere Chair Holland N. O'Neil. "Each of these distinguished attorneys has demonstrated the ability to contribute substantially to the strategic objectives of their practice groups and the Firm. We are delighted to welcome them ...