Barcelona, Spain – Saturday 30 August 2014: The first recommendations on the use of all new oral anticoagulants in pulmonary embolism are published today in new ESC Guidelines. The guidelines are launched at ESC Congress by Professor Stavros V. Konstantinides (Germany/Greece) and Professor Adam Torbicki (Poland). The "2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism" are published today online in European Heart Journal (1) and on the ESC Website. Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism (PE). ...

Barcelona, Spain – Saturday 30 August 2014: A new sudden death predictor for patients with hypertrophic cardiomyopathy (HCM) identifies candidates for implantable cardioverter defibrillators (ICDs) in ESC Guidelines published today. They are presented at ESC Congress by Task Force Chairperson Professor Perry Elliott (UK). The "2014 ESC Guidelines on Diagnosis and Management of Hypertrophic Cardiomyopathy" are published today on-line in the European Heart Journal (1) and on the ESC Website. Previous ESC Guidelines on hypertrophic cardiomyopathy were published in 2003 (2). Professor ...

Barcelona, Spain – Saturday 30 August 2014: The therapeutic benefit of revascularisation in coronary artery disease (CAD) is emphasised in the 2014 ESC/EACTS revascularisation guidelines presented at ESC Congress by joint Task Force Chairs Professor Stephan Windecker (Switzerland) of the European Society of Cardiology (ESC) and Professor Philippe Kolh (Belgium) of the European Association for Cardio-Thoracic Surgery (EACTS). The joint guidelines are published today on-line in European Heart Journal (1), on the ESC Website (2), in EuroIntervention and in the European Journal ...

Researchers at UC Davis have made some surprising discoveries about the body's initial responses to HIV infection. Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin-1 beta (IL-1β). Though aimed at the presence of virus, IL-1β causes breakdown of the gut epithelium that provides a barrier to protect the body against pathogens. Importantly, this occurs prior to the wide ...

SAN ANTONIO (Aug. 29, 2014) — Scientists at the Barshop Institute for Longevity and Aging Studies, part of the School of Medicine at the UT Health Science Center at San Antonio, have found another secret of longevity in the tissues of the longest-lived rodent, the naked mole rat. They reported that a factor in the cells of naked mole rats protects and alters the activity of the proteasome, a garbage disposer for damaged and obsolete proteins. The factor also protects proteasome function in human, mouse and yeast cells when challenged with various proteasome poisons, ...

A new report released yesterday by the Mental Health Commission of Canada identifies ways to improve the mental health training and education that police personnel receive. "People with mental illnesses is a prominent issue for Canada's police community, and today's report builds on the increasingly collaborative relationship between law enforcement and people with mental illnesses," says Queen's adjunct professor Dorothy Cotton, a forensic psychologist with an interest in the area of police psychology. "This is a gap-analysis tool that police academy and police services ...

NEW YORK – August 29, 2014 - Despite US Preventive Services Task Force recommendations for screening and treating obesity, there are many barriers, several of which may be ameliorated through technological approaches according to a new study by researchers at NYU Langone Medical Center published online August 21, 2014 in the Journal of General Internal Medicine (JGIM). David Levine, MD, MA, a third year resident in the Department of Internal Medicine at NYU Langone, and colleagues found that compared to usual care, technology-assisted interventions specifically in the ...

After a systematic review of clinical trials based on administering antidepressants for acute and chronic postsurgical pain, researchers have concluded that more trials are needed to determine whether these drugs should be prescribed for postsurgical pain on a regular basis. Dr. Ian Gilron, a professor and director of clinical pain research in the Department of Anesthesiology, and his team of seven researchers reviewed 15 trials to determine whether the use of antidepressants for pain relief post-surgery would work more effectively than painkillers such as opioids, local ...

A leading U.S. Ebola researcher from the University of Texas Medical Branch at Galveston has gone on record stating that a blend of three monoclonal antibodies can completely protect monkeys against a lethal dose of Ebola virus up to 5 days after infection, at a time when the disease is severe. Thomas Geisbert, professor of microbiology and immunology, has written an editorial for Nature discussing advances in Ebola treatment research. The filoviruses known as Ebola virus and Marburg virus are among the most deadly of pathogens, with fatality rates of up to 90 percent. ...

Dartmouth researchers explored the type and number of connections in transcription factor networks (TFNs) to evaluate the role assortativity plays on robustness in a study published in PLOS Computational Biology in August. The study found that the assortativity signature contributes to a network's resilience against mutations. "In simulations, it seems that varying the out-out assortativity of TFN models has a greater effect on robustness than varying any of the other three types of assortativity," said Dov A. Pechenick, PhD, lead author and former researcher at the ...

Raloxifene is a U.S. Food and Drug Administration (FDA)-approved treatment for decreasing fracture risk in osteoporosis. While raloxifene is as effective at reducing fracture risk as other current treatments, this works only partially by suppressing bone loss. With the use of wide- and small-angle x-ray scattering (WAXS and SAXS, respectively), researchers carried out experiments at the U.S. Department of Energy's (DOE's) Advanced Photon Source (APS) at Argonne National Laboratory that revealed an additional mechanism underlying raloxifene action, providing an explanation ...

Researchers at the Washington University School of Medicine have identified one way the Ebola virus dodges the body's antiviral defenses, providing important insight that could lead to new therapies, in research results published in the journal Cell Host & Microbe. In work performed at Beamline 19ID at Argonne National Laboratory's Advanced Photon Source, the researchers developed a detailed map of how a non-pathogenic Ebola protein, VP24, binds to a host protein that takes signaling molecules in and out of the cell nucleus. Their map revealed that the viral protein ...

Making something new is never easy. Scientists constantly theorize about new materials, but when the material is manufactured it doesn't always work as expected. To create a new strategy for designing materials, scientists at the Department of Energy's Argonne National Laboratory combined two different approaches at two different facilities to synthesize new materials. This new strategy gives faster feedback on what growth schemes are best, thus shortening the timeframe to manufacture a new, stable material for energy transport and conversion applications. A recent ...

Boulder, Colorado, USA – In the September issue of GSA Today, Paul Bierman of the University of Vermont–Burlington and colleagues present a cosmogenic view of erosion, relief generation, and the age of faulting in southernmost Africa. By measuring beryllium-10 (10Be) in river sediment samples, they show that south-central South Africa is eroding at the slow rate of about five meters per million years, consistent with rates in other non-tectonically active regions. By measuring 10Be and aluminum-26 (26Al) in exposed quartzites, Bierman and colleagues find that undeformed ...

EDMONTON, AB – A new study from the research group of Dr. John Lewis at the University of Alberta (Edmonton, AB) and the Lawson Health Research Institute (London, ON) has confirmed that "invadopodia" play a key role in the spread of cancer. The study, published in Cell Reports, shows preventing these tentacle-like structures from forming can stop the spread of cancer entirely. Roughly 2 in 5 Canadians will develop cancer in their lifetime, and one in four of them will die of the disease. In 2014, it's estimated that nine Canadians will die of cancer every hour. Thanks ...

Water scarcity is not a problem just for the developing world. In California, legislators are currently proposing a $7.5 billion emergency water plan to their voters; and U.S. federal officials last year warned residents of Arizona and Nevada that they could face cuts in Colorado River water deliveries in 2016. Irrigation techniques, industrial and residential habits combined with climate change lie at the root of the problem. But despite what appears to be an insurmountable problem, according to researchers from McGill and Utrecht University it is possible to turn the ...

Toronto, Canada – Older adults who stay active by volunteering are getting more out of it than just an altruistic feeling – they are receiving a health boost! A new study, led by the Rotman Research Institute at Baycrest Health Sciences and published online this week in Psychological Bulletin, is the first to take a broad-brush look at all the available peer-reviewed evidence regarding the psychosocial health benefits of formal volunteering for older adults. Lead investigator Dr. Nicole Anderson, together with scientists from Canadian and American academic centres, ...

Satellite imagery shows Hurricane Cristobal racing through the North Atlantic on Friday, August 29 while losing its tropical characteristics. An image from NOAA's GOES-East satellite showed Cristobal headed south of Greenland. The previous day, NASA's TRMM satellite saw heavy rainfall occurring in the hurricane. In a visible image from NOAA's GOES-East satellite on August 29 at 7:45 a.m. EDT, Hurricane Cristobal was moving through the North Atlantic about 500 miles southwest of Greenland. The image was created by the NASA/NOAA GOES Project at NASA's Goddard Space Flight ...

To understand how the repeated climatic shifts over the last 120,000 years may have influenced today's patterns of genetic diversity, a team of researchers led by City College of New York biologist Dr. Ana Carnaval developed a new biodiversity metric called "phylogeographic endemism." It quantifies the degree to which the genetic variation within species is restricted in geographical space. Dr. Carnaval, an assistant professor of biology, and 14 other researchers from institutions in Brazil, Australia and the United States, analyzed the effects of current and past climatic ...

This news release is available in German. Nitrite-oxidizing bacteria are key players in the natural nitrogen cycle on Earth and in biological wastewater treatment plants. For decades, these specialist bacteria were thought to depend on nitrite as their source of energy. An international team of scientists led by Holger Daims, a microbiologist at the University of Vienna, has now shown that nitrite-oxidizing bacteria can use hydrogen as an alternative source of energy. The oxidation of hydrogen with oxygen enables their growth independent of nitrite and a lifestyle outside ...

VIDEO: This video of NOAA's GOES-West satellite imagery from Aug. 26-29 shows Hurricane Marie winding down into a post-tropical storm. Click here for more information. NOAA's GOES-West satellite keeps a continuous eye on the Eastern Pacific and has been covering Hurricane Marie since birth. NASA's GOES Project uses NOAA data and creates animations and did so to show the end of Hurricane Marie. At 5 a.m. EDT (0900 UTC) on Friday, August 29, Marie became a post-tropical storm ...

To the careful observer, a person's face has long provided insight into what is going on beneath the surface. Now, with the assistance of a web camera and software algorithms, the face can also reveal whether or not an individual is experiencing atrial fibrillation, a treatable but potentially dangerous heart condition. A pilot project, the results of which were published online today in the journal Heart Rhythm, demonstrates that subtle changes in skin color can be used to detect the uneven blood flow caused by atrial fibrillation. The technology was developed in a ...

Some species of marine phytoplankton, such as the prolific bloomer Emiliania huxleyi, can grow without consuming vitamin B1 (thiamine), researchers have discovered. The finding contradicts the common view that E. huxleyi and many other eukaryotic microbes depend on scarce supplies of thiamine in the ocean to survive. "It's a really different way to think about the ocean," says CIFAR Senior Fellow Alexandra Worden, co-author on The ISME Journal paper with CIFAR fellows John Archibald (Dalhousie University), Adrián Reyes-Prieto (University of New Brunswick) and three lead ...

This news release is available in German. The exchange of chemical signals between organisms is considered the oldest form of communication. Acting as messenger molecules, pheromones regulate social interactions between conspecifics, for example, the sexual attraction between males and females. Fish rely on pheromones to trigger social responses and to coordinate reproductive behavior in males and females. Scientists at the Marine Science Center at the University of the Algarve in Faro, Portugal, and at the Max Planck Institute for Chemical Ecology in Jena, Germany, ...

In almost 20 years, China's R&D expenditure as a percentage of its gross domestic product has more than tripled, reaching 1.98 per cent in 2012. This figure surpasses the 28 member states of the EU, which collectively managed 1.96 per cent. However, despite this, China saw a sharp decline in money spent on scientific research, in particular applied research. Basic research funding plummeted from 5.2 per cent in 1995 to 4.7 per cent in 2011, and applied research funding fell from 26.4 per cent to 11.8 per cent in the same years. This is Dr Cao's second Science article ...