Using antibiotics alone to treat children with uncomplicated acute appendicitis is a reasonable alternative to surgery that leads to less pain and fewer missed school days, according to a pilot study. The research, led by a team at Nationwide Children's Hospital and published online April 12 in the Journal of the American College of Surgeons, is the first prospective study on nonoperative management of acute appendicitis in pediatric patients in the United States. Researchers enrolled 77 patients age 7 to 17 who were diagnosed with uncomplicated acute appendicitis by ...

COLUMBUS, Ohio – Heart patients with beliefs about health that aren't based on medical evidence are more likely to skip sessions of cardiac rehabilitation, new research suggests. In the Ohio State University study, a higher number of these beliefs – referred to as "irrational health beliefs" on a standard measure of these thoughts – was associated with lower adherence to a prescribed cardiac rehab program. Among the irrational beliefs assessed: Doubting the preventive power of the flu vaccine or believing, based on family history alone, that it's safe to smoke cigarettes ...

Scientists at Chicago's Field Museum and international collaborators have reconstructed the phylogeny and biological history for the Yellow-shouldered bats in the New World tropics, the region of the Earth surrounding the equator. In-depth analysis of mitochondrial and nuclear DNA sequences uncovered three species new to science, each having previously been confused with another species. Since 1960, when modern studies on this group began, Sturnira has grown from eight species to 22. The newest additions were described in a new study, published online in ZooKeys. The ...

SOUTH SAN FRANCISCO, Calif.--True North Therapeutics, Inc., announced today a publication demonstrating that the company's C1s antibody prevents the destruction of human red blood cells exposed to plasma samples of patients with a type of autoimmune hemolytic anemia (AIHA). The article entitled "TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinin disease patient autoantibodies" was published on-line in the journal Blood earlier this month. TNT003 is the murine analog of True North's lead humanized monoclonal antibody ...

By tracking brain activity when an animal stops to look around its environment, neuroscientists at the Johns Hopkins University believe they can mark the birth of a memory. Using lab rats on a circular track, James Knierim, professor of neuroscience in the Zanvyl Krieger Mind/Brain Institute at Johns Hopkins, and a team of brain scientists noticed that the rats frequently paused to inspect their environment with head movements as they ran. The scientists found that this behavior activated a place cell in their brain, which helps the animal construct a cognitive map, ...

New technologies for developing electronics and optoelectronics with tunable/adaptive functionalities and performance are critical to emerging applications in wearable technology, communication, pervasive computing, human-machine interfacing and biomedical diagnostics, in which the active and adaptive interactions between devices and stimuli from the ambient/host (e. g. human body) are essential. Mechanical stimuli are ubiquitous and abundant in the environment for interacting with or controlling these electronics/optoelectronics. This is, however, not facile to implement ...

Quantum superposition is a fundamental and also intriguing property of the quantum world. Because of superposition, a quantum system can be in two different states simultaneously, like a cat that can be both "dead" and "alive" at the same time. However, this anti-intuitive phenomenon cannot be observed directly, because whenever a classical measuring tool touches a quantum system, it immediately collapse into a classical state. On the other hand, quantum superposition is also the core of quantum computer's enormous computational power. A quantum computer can easily break ...

Wondering what makes an ICT hotspot? Take a look at Munich, London, Paris or smaller cities such as Darmstadt identified in a new EU Atlas of ICT hotspots. This atlas shows where digital technologies thrive and examines the factors contributing to this success. Most of Europe's ICT activity takes place in 34 regions across 12 countries (listed in the Annex). Key ingredients to success included access to top Universities and research centres and funding opportunities such as venture capital. European Commission Vice-President @NeelieKroesEU said: "This is proof that ...

Glacial cycles at 104-yr time scale have been the focus of Quaternary paleoclimatology over the last century. In recent years with the emergence of continuous high-resolution records (ice cores, deep-sea sediments etc.) from the longer geological past, increasing evidence underscores the significance of long- duration processes at the time scale of 105-yr or more. WANG Pinxian and colleagues from the State Key Laboratory of Marine Geology, Tongji University, reviewed long-term variations in the oceanic carbon reservoir and indicated their crucial role in major climate regime ...

Tobacco, a high-density crop which is mown several times throughout its cycle, can produce as much as 160 tonnes of fresh matter per hectare and become a source of biomass suitable for producing bioethanol. As Jon Veramendi, head of the plant Agrobiotechnology research group, explained, "tobacco plants as a source of biomass for producing bioethanol could be an alternative to traditional tobacco growing which is in decline in the USA and in Europe because it cannot compete with emerging countries like China". In the course of the research, which has been echoed by the ...

The headwaters for Puget Sound's famously rich waters lie far below the surface, in a submarine canyon that draws nutrient-rich water up from the deep ocean. New measurements may explain how the Pacific Northwest's inland waters are able to support so many shellfish, salmon runs and even the occasional pod of whales. University of Washington oceanographers made the first detailed measurements at the headwater's source, a submarine canyon offshore from the strait that separates the U.S. and Canada. Observations show water surging up through the canyon and mixing at surprisingly ...

A new study shows that domestic abuse is closely linked to postpartum mental health problems, including depression and post-traumatic stress disorder (PTSD), in mothers. The research also found that specific types of abuse are associated with specific mental health problems. The work was done by researchers at North Carolina State University, Simon Fraser University and the University of British Columbia. "We wanted to see whether and how intimate partner abuse – physical, psychological and sexual – influenced postpartum mental health in women, including problems such ...

This news release is available in Spanish. Until now, the carbon 14 technique, a radioactive isotope which gradually disappears with the passing of time, has been used to date prehistoric remains. When about 40,000 years, in other words approximately the period corresponding to the arrival of the first humans in Europe, have elapsed, the portion that remains is so small that it can become easily contaminated and cause the dates to appear more recent. It was from 2005 onwards that a new technique began to be used; it is the one used to purify the collagen in DNA tests. ...

WASHINGTON, April 14—In dense, urban centers around the world, many people live and work in dim and narrow streets surrounded by tall buildings that block sunlight. And as the global population continues to rise and buildings are jammed closer together, the darkness will only spread. To alleviate the problem, Egyptian researchers have developed a corrugated, translucent panel that redirects sunlight onto narrow streets and alleyways. The panel is mounted on rooftops and hung over the edge at an angle, where it spreads sunlight onto the street below. The researchers describe ...

Dog owners in the Caucasus Mountains of Georgia might want to consider penning up their dogs more often: hybridization of wolves with shepherd dogs might be more common, and more recent, than previously thought, according to a recently published study in the Journal of Heredity (DOI: 10.1093/jhered/esu014). Dr. Natia Kopaliani, Dr. David Tarkhnishvili, and colleagues from the Institute of Ecology at Ilia State University in Georgia and from the Tbilisi Zoo in Georgia used a range of genetic techniques to extract and examine DNA taken from wolf and dog fur samples as well ...

LA JOLLA, Calif., April 11, 2014 — A team of scientists led by Pier Lorenzo Puri, M.D., associate professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham), in collaboration with Fondazione Santa Lucia in Rome, Italy, have published details of how a class of drugs called "HDACis" drive muscle-cell regeneration in the early stages of dystrophic muscles, but fail to work in late stages. The findings are key to furthering clinical development of HDACis for Duchenne muscular dystrophy (DMD), an incurable muscle-wasting disease. A symphony to rebuild muscle The ...

One of the great problems in physics is the detection of electromagnetic radiation – that is, light – which lies outside the small range of wavelengths that the human eye can see. Think X-rays, for example, or radio waves. Now, researchers have discovered a way to use existing semiconductors to detect a far wider range of light than is now possible, well into the infrared range. The team hopes to use the technology in detectors, obviously, but also in improved solar cells that could absorb infrared light as well as the sun's visible rays. "This technology will also ...

A study in The Journal of General Physiology provides new insights about singlet oxygen and sets the stage for better understanding of this highly reactive and challenging substance. Singlet oxygen is an electronically excited state of oxygen that is less stable than normal oxygen. Its high reactivity has enabled its use in photodynamic therapy, in which light is used in combination with a photosensitizing drug to generate large amounts of singlet oxygen to kill cancer cells or various pathogens. Light-generated singlet oxygen also plays a role in a range of biological ...

Changes at the atom level in nanowires offer vast possibilities for improvement of solar cells and LED light. NTNU-researchers have discovered that by tuning a small strain on single nanowires they can become more effective in LEDs and solar cells. NTNU researchers Dheeraj Dasa and Helge Weman have, in cooperation with IBM, discovered that gallium arsenide can be tuned with a small strain to function efficiently as a single light-emitting diode or a photodetector. This is facilitated by the special hexagonal crystal structure, referred to as wurtzite, which the NTNU ...

Scientists at Umeå University in Sweden have found that carbon dioxide, in its ionic form bicarbonate, has a regulating function in the splitting of water in photosynthesis. This means that carbon dioxide has an additional role to being reduced to sugar. The pioneering work is published in the latest issue of the scientific journal PNAS. It is well known that inorganic carbon in the form of carbon dioxide, CO2, is reduced in a light driven process known as photosynthesis to organic compounds in the chloroplasts. Less well known is that inorganic carbon also affects the ...

This news release is available in German. Although persistent environmental pollutants have been and continue to be released worldwide, the Arctic and Antarctic regions are significantly more contaminated than elsewhere. The marine animals living there have some of the highest levels of persistent organic pollutant (POP) contamination of any creatures. The Inuit people of the Arctic, who rely on a diet of fish, seals and whales, have also been shown to have higher POP concentrations than people living in our latitudes. Today, the production and use of nearly two dozen ...

The ability of forests to sequester carbon from the atmosphere depends on nutrients available in the forest soils, shows new research from an international team of researchers including the International Institute for Applied Systems Analysis (IIASA). The study showed that forests growing in fertile soils with ample nutrients are able to sequester about 30% of the carbon that they take up during photosynthesis. In contrast, forests growing in nutrient-poor soils may retain only 6% of that carbon. The rest is returned to the atmosphere as respiration. "This paper produces ...

Using DESY's bright research light sources, scientists have opened a new door to better solar cells, novel superconductors and smaller hard-drives. The research reported in the scientific journal Nature Communications this week enhances the understanding of the interface of two materials, where completely new properties can arise. With their work, the team of Prof. Andrivo Rusydi from the National University of Singapore and Prof. Michael Rübhausen from the Hamburg Center for Free-Electron Laser Science (CFEL) have solved a long standing mystery in the physics of condensed ...

This news release is available in German. Miniaturized optical frequency comb sources allow for transmission of data streams of several terabits per second over hundreds of kilometers – this has now been demonstrated by researchers of Karlsruhe Institute of Technology (KIT) and the Swiss École Polytechnique Fédérale de Lausanne (EPFL) in a experiment presented in the journal Nature Photonics. The results may contribute to accelerating data transmission in large computing centers and worldwide communication networks. (DOI: 10.1038/NPHOTON.2014.57.) The amount of ...

April 2014, Perth, Australia. Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein biomarkers. The research team authenticated the panel of biomarkers after taking 508 highly curated disease and control samples. Seven biomarkers were validated at high stringency using the company's proprietary mass spectrometry approach. The mass spectrometry data was then cross-validated using immunoassays in collaboration with the KTH Royal Institute ...