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Genetics used to sort out poorly known -- and hunted -- whale species

2013-10-04
Saving the whales often means knowing—sometimes genetically—one group of whales from another, say researchers attempting to define populations of a medium-sized and poorly understood baleen whale that is sometimes targeted by Japan's scientific whaling program. In a new study, scientists from Wildlife Conservation Society, the American Museum of Natural History, Columbia University, NOAA, and other groups are working to define separate groups and subspecies of the Bryde's whale in the Indian and western Pacific Oceans. By generating genetic information that allowed ...

New data-driven machine learning method effectively flags risk for post-stroke dangers

2013-10-04
PHILADELPHIA - A team of experts in neurocritical care, engineering, and informatics, with the Perelman School of Medicine at the University of Pennsylvania, have devised a new way to detect which stroke patients may be at risk of a serious adverse event following a ruptured brain aneurysm. This new, data-driven machine learning model, involves an algorithm for computers to combine results from various uninvasive tests to predict a secondary event. Preliminary results were released at the Neurocritical Care Society Annual Meeting in Philadelphia. Comparing 89 patient ...

Johns Hopkins experts devise a way to cut radiation exposure in children needing repeat brain scans

2013-10-04
A team of pediatric neurosurgeons and neuroradiologists at the Johns Hopkins Children's Center has developed a way to minimize dangerous radiation exposure in children with a condition that requires repeat CT scans of the brain. The experts say they reduced exposure without sacrificing the diagnostic accuracy of the images or compromising treatment decisions. The approach, described ahead of print in a report in the Journal of Neurosurgery, calls for using fewer X-ray snapshots or "slices" of the brain taken by CT scanners ­ seven instead of the usual 32 to 40 slices. ...

Naked jets of water make a better pollutant detector

2013-10-04
WASHINGTON, Oct. 3, 2013—When you shine ultraviolet light (UV) through water polluted with certain organic chemicals and bacteria, the contaminants measurably absorb the UV light and then re-emit it as visible light. Many of today's more advanced devices for testing water are built to make use of this fluorescent property of pollutants; but the walls of the channels through which the water travels in these devices can produce background noise that makes it difficult to get a clear reading. Reported today, in The Optical Society's (OSA) open-access journal, Optics Express, ...

Native tribes' traditional knowledge can help US adapt to climate change

2013-10-04
New England's Native tribes, whose sustainable ways of farming, forestry, hunting and land and water management were devastated by European colonists four centuries ago, can help modern America adapt to climate change. That's the conclusion of more than 50 researchers at Dartmouth and elsewhere in a special issue of the journal Climatic Change. It is the first time a peer-reviewed journal has focused exclusively on climate change's impacts on U.S. tribes and how they are responding to the changing environments. Dartmouth also will host an Indigenous Peoples Climate Change ...

CU-Boulder researchers use climate model to better understand electricity in the air

2013-10-04
Electrical currents born from thunderstorms are able to flow through the atmosphere and around the globe, causing a detectable electrification of the air even in places with no thunderstorm activity. But until recently, scientists have not had a good understanding of how conductivity varies throughout the atmosphere and how that may affect the path of the electrical currents. Now, a research team led by the University of Colorado Boulder has developed a global electric circuit model by adding an additional layer to a climate model created by colleagues at the National ...

Molecular imaging predicts risk for abdominal aortic aneurysms

2013-10-04
Reston, Va. – Several newly identified markers could provide valuable insight to predict the risk of rupture abdominal aortic aneurysms (AAA), according to new research published in the October issue of the Journal of Nuclear Medicine. Imaging with positron emission tomography/computed tomography (PET/CT) has shown that dense white blood cells in the outermost connective tissue in the vascular wall, increased C-reactive protein and a loss of smooth muscle cells in the middle layer of the vascular wall are all factors that may indicate future AAA rupture. An abdominal ...

How an aggressive fungal pathogen causes mold in fruits and vegetables

2013-10-04
RIVERSIDE, Calif. — A research team led by a molecular plant pathologist at the University of California, Riverside has discovered the mechanism by which an aggressive fungal pathogen infects almost all fruits and vegetables. The team discovered a novel "virulence mechanism" — the mechanism by which infection takes place — of Botrytis cinerea. This pathogen can infect more than 200 plant species, causing serious gray mold disease on almost all fruits and vegetables that have been around, even at times in the refrigerator, for more than a week. Study results appear ...

Warmer oceans could raise mercury levels in fish

2013-10-04
Rising ocean surface temperatures caused by climate change could make fish accumulate more mercury, increasing the health risk to people who eat seafood, Dartmouth researchers and their colleagues report in a study in the journal PLOS ONE. Until now, little has been known about how global warming may affect mercury bioaccumulation in marine life, and no previous study has demonstrated the effects using fish in both laboratory and field experiments. Mercury released into the air through industrial pollution can accumulate in streams and oceans and is turned into methylmercury ...

Researchers find that bright nearby double star Fomalhaut is actually a triple

2013-10-04
The nearby star system Fomalhaut – of special interest for its unusual exoplanet and dusty debris disk – has been discovered to be not just a double star, as astronomers had thought, but one of the widest triple stars known. In a paper recently accepted for publication in the Astronomical Journal and posted today to the preprint server arXiv, researchers show that a previously known smaller star in its vicinity is also part of the Fomalhaut system. Eric Mamajek, associate professor of physics and astronomy at the University of Rochester, and his collaborators found ...

Cancer survivors in rural areas forgo health care because of cost

2013-10-04
PHILADELPHIA — Older cancer survivors living in rural areas were more likely to forgo medical and dental care because of financial concerns compared with older cancer survivors living in urban areas, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. Data analysis showed cancer survivors in rural areas who were aged 65 or older were 66 percent more likely to forgo medical care and 54 percent more likely to forgo dental care because of cost, compared with their urban counterparts. "This ...

Walking can reduce breast cancer risk

2013-10-04
PHILADELPHIA — Postmenopausal women who were very active or walked for at least seven hours a week had a reduced risk for breast cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. Women who engaged in at least an hour of vigorous physical activity every day had a 25 percent lower risk for breast cancer, and those who walked for at least seven hours a week had a 14 percent lower risk for breast cancer, in this study of 73,615 postmenopausal women. "We examined whether recreational ...

Study links moderate activity to lower breast cancer risk

2013-10-04
ATLANTA -- October 4, 2013 -- A large new American Cancer Society study adds to increasing evidence that physical activity reduces the risk of breast cancer in postmenopausal women. Researchers say moderate recreational activity was associated with a 14 percent lower risk and high physical activity with a 25 percent lower risk of breast cancer compared to women who were active at the lowest level. The study appears early online in Cancer Epidemiology, Biomarkers, and Prevention. A large body of evidence shows that women taking part in regular physical activity have an ...

Laying down a discerning membrane

2013-10-04
One of the thinnest membranes ever made is also highly discriminating when it comes to the molecules going through it. Engineers at the University of South Carolina have constructed a graphene oxide membrane less than 2 nanometers thick with high permeation selectivity between hydrogen and carbon dioxide gas molecules. The selectivity is based on molecular size, the team reported in the journal Science. Hydrogen and helium pass relatively easily through the membrane, but carbon dioxide, oxygen, nitrogen, carbon monoxide and methane permeate much more slowly. "The hydrogen ...

Rutgers scientists discover molecules that show promise for new anti-flu medicines

2013-10-04
NEW BRUNSWICK, N.J. – A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture. These novel compounds show promise for a new class of antiviral medicines to fight much-feared pandemic influenzas such as the looming "bird flu" threats caused by the H5N1 influenza A virus and the new H7N9 virus responsible for a 2013 outbreak in China. Timely production of a vaccine is difficult when a pandemic flu strikes. A viable alternative ...

HydroEye(R) benefits post-menopausal dry eye sufferers in new clinical research

2013-10-03
HOUSTON, TX—October 2, 2013—Study findings published in the October issue of Cornea show that daily dietary supplementation with a unique combination of omega fatty acids (GLA, EPA and DHA) for six months is effective in improving ocular irritation symptoms and halting the progression of inflammation that characterizes moderate to severe dry eye. The multi-center, double-blind, randomized, placebo-controlled clinical trial evaluated 38 post-menopausal women with tear dysfunction in both eyes. HydroEye® (ScienceBased Health®) was found to improve ocular irritation symptoms, ...

Why blame feels hard to take

2013-10-03
When something we do produces a positive result, we actually perceive it differently than we would if that same action yielded a negative result. In particular, people feel a greater connection between voluntary actions and their outcomes if those outcomes are good than if they are bad. The discovery, reported on October 3 in Current Biology, a Cell Press publication, yields important insight into notions about personal responsibility. "Our result suggests that people may really experience less responsibility for negative than for positive outcomes," says Patrick Haggard ...

A metabolic means to preserving egg supply and fertility

2013-10-03
The stresses that come with aging, chemotherapy treatments, and environmental exposures all threaten fertility. But what if there were a way to preserve women's limited egg supply? Researchers reporting on studies conducted in frog and mouse eggs in the Cell Press journal Molecular Cell on October 3rd may have found a way. The findings come at an important time when many women are waiting longer and longer to have children, renewing interest in the development of strategies to preserve oocytes—immature egg cells. "Our work provides insight into how oocyte viability ...

Leading experts offer advice on generating human induced pluripotent stem cell banks

2013-10-03
The ability to make induced pluripotent stem cells (iPSCs) from mature cells in the body holds great potential for improved drug screening, disease modeling, and medical treatments for numerous conditions. Establishing well-characterized panels of iPSC lines that reflect the diversity of the human population and include samples from patients with a wide range of diseases will be key to tapping into the potential of iPSCs. In the October 3 issue of the Cell Press journal Cell Stem Cell, leading experts in the field publish several opinion pieces on emerging issues related ...

Key cellular auto-cleaning mechanism mediates the formation of plaques in Alzheimer's brain

2013-10-03
Autophagy, a key cellular auto-cleaning mechanism, mediates the formation of amyloid beta plaques, one of the hallmarks of Alzheimer's disease. It might be a potential drug target for the treatment of the disease, concludes new research from the RIKEN Brain Science Institute in Japan. The study sheds light on the metabolism of amyloid beta, and its role in neurodegeneration and memory loss. In a study published today in the journal Cell Reports, Drs. Per Nilsson, Takaomi Saido and their team show for the first time using transgenic mice that a lack of autophagy in neurons ...

Wealth inequality can promote cooperation

2013-10-03
Wealth inequality can encourage people to cooperate when they would otherwise have no incentive to do so, according to a new study published in Nature Communications. "In many groups and societies, the temptation to defect is high, which means that cheaters are much better off than cooperators," says IIASA researcher Ulf Dieckmann, who worked on the study along with IIASA researcher Ádám Kun. For example, he says, if a train ticket is very expensive and the probability that cheaters are caught is low, people will be tempted to free-ride without purchasing a ticket. Likewise, ...

Power of precision medicine shown in successful treatment of patient with disabling OCD

2013-10-03
Cold Spring Harbor, NY -- A multidisciplinary team led by a geneticist and psychiatrist from Cold Spring Harbor Laboratory's (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called "precision medicine." Precision medicine is an approach to diagnosis and treatment that tailors therapeutic care to individuals in a highly specific manner, and which brings to bear powerful new technologies that have not yet made it into the mainstream of clinical medicine, ...

Diesel exhaust stops honeybees from finding the flowers they want to forage

2013-10-03
Exposure to common air pollutants found in diesel exhaust pollution can affect the ability of honeybees to recognise floral odours, new University of Southampton research shows. Honeybees use floral odours to help locate, identify and recognise the flowers from which they forage. The Southampton team, led by Dr Tracey Newman and Professor Guy Poppy, found that diesel exhaust fumes change the profile of flora odour. They say that these changes may affect honeybees' foraging efficiency and, ultimately, could affect pollination and thus global food security. Published ...

High rates of unnecessary prescribing of antibiotics observed across the US

2013-10-03
Boston, MA – For decades, there has been a significant effort led by the Centers for Disease Control and Prevention and others to reduce inappropriate antibiotic prescribing. Despite this work, new research from Brigham and Women's Hospital (BWH) finds only incremental improvement in antibiotic prescribing for adults with acute bronchitis and sore throat. These findings were presented at IDWeek on October 3, 2013 and the sore throat data was published online in JAMA Internal Medicine. "We know that antibiotic prescribing, particularly to patients who are not likely ...

Rett syndrome gene dysfunction redefined

2013-10-03
CAMBRIDGE, Mass. (October 3, 2013) – Whitehead Institute researchers have redefined the function of a gene whose mutation causes Rett syndrome, a neurodevelopmental autism spectrum disorder. This new research offers an improved understanding of the defects found in the neurons of Rett syndrome patients and could lead to novel therapies for the disease. "The action of the MECP2 protein is just the opposite of how it was held for the past 15 years," says Whitehead Founding Member Rudolf Jaenisch, who is also a professor of biology at MIT. "It was thought that this protein ...
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