“[...] it appears that the CCR4-NOT complex can influence longevity in a multitude of manners [...]” BUFFALO, NY- June 11, 2024 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, “CCR4-NOT complex in stress resistance and longevity in C. elegans.” The ability to mount an adaptive response to environmental stress is crucial in organismal survival and overall fitness. In the context of aging, many genes that mediate resistance to stressors are also important in longevity, and aging has been shown to cause ...

Subscribe to UCSF News Note to Editors: Speaker bios are available in our media kit   UCSF Health and UCSF Benioff Children’s Hospitals celebrated the signing of a Community Workforce Agreement (CWA) on June 11, agreeing to prioritize local union workers for the construction of a proposed landmark hospital building and related site improvements on its Oakland site.     The agreement, signed by the Building and Construction Trades Council of Alameda County (BTCA) and the project’s general contractor, Rudolph and Sletten, confirms a mutual understanding to hire union workers and follow union hiring practices. An additional agreement was signed by Overaa Construction, ...

ITHACA, N.Y. – An artificial intelligence-powered virtual teammate with a female voice boosts participation and productivity among women on teams dominated by men, according to new Cornell University research. The findings suggest that the gender of an AI’s voice can positively tweak the dynamics of gender-imbalanced teams and could help inform the design of bots used for human-AI teamwork, researchers said. The findings mirror previous research that shows minority teammates are more likely to participate if the team adds members similar to them, said Angel Hsing-Chi Hwang, postdoctoral associate in information science and ...

The human visual system is a dominant part of the brain’s processes and navigation of the world. To better understand an aspect of this system, researchers from Drexel University’s College of Nursing and Health Professions examined how life experiences impact a person’s perception of imagery – specifically decorated masks. The study, published in Frontiers in Psychology, examined viewer responses to images of distressing and neutrally decorated masks and whether personal life history, particularly past ...

TAMPA, Fla. — Leptomeningeal disease is a rare but lethal complication faced by late-stage melanoma patients. It occurs when cancer cells spread to the membranes covering the brain and spinal cord, or the leptomeninges. This condition, which affects 5% to 8% of melanoma patients, often leads to rapid deterioration and is notoriously resistant to therapies. However, a new Moffitt Cancer Center study, published today in Cell Reports Medicine, uncovers the mechanisms that drive this drug resistance, offering new avenues ...

Iran’s water policy is discriminatory and an example of environmental racism, with specific regions and ethnic groups deliberately impoverished, damaged and threatened by policymakers, a new study says. Water scarcity lies at the core of Iran’s environmental crises. Approximately 28 million of Iran’s 85 million residents reside in water-stressed areas, a situation identified as ‘water bankruptcy’. This is particularly the case in the central, industrialised regions. Other “donor basin” regions – which have ...

The 2024 Warren Alpert Foundation Prize has been awarded to four scientists whose transformational discoveries led to the creation of chimeric antigen receptor (CAR) T cells, a treatment that modifies patients’ immune cells and optimizes their ability to eliminate cancer cells. CAR T-cell therapy, the first successful example of synthetic biology used in clinical medicine, has saved the lives of tens of thousands of adults and children with blood cancers, including leukemia, lymphoma, and multiple myeloma. The award recipients are: Renier Brentjens, Katherine Anne Gioia Endowed Chair of Medicine and deputy director of Roswell Park Comprehensive Cancer Center   Zelig ...

Metabolic syndrome (MetS) is a health condition characterized by a group of risk factors: high blood pressure, high blood sugar, unhealthy cholesterol levels, and abdominal fat. These factors increase the risk of heart disease, type 2 diabetes, and other serious health problems. Previous studies have shown that both genetics and lifestyle influence MetS. But human studies have found it challenging to pinpointing the disease’s exact genetic factors and how they interact with our environment – the differences between people’s diets and lifestyles have proven impossible to control. Now, scientists led by Johan Auwerx at EPFL have addressed ...

WhatsApp can be a highly effective tool to help older people overcome loneliness and depression, according to the findings of a study conducted in Guarulhos, the second-largest city in São Paulo state, Brazil.  An article on the study is published in the journal Nature Medicine. The co-corresponding author is Marcia Scazufca, a scientific researcher at Hospital das Clínicas (HC), the hospital complex run by the University of São Paulo’s Medical School (FM-USP), and a professor at the school. “This was a randomized controlled trial involving 603 participants aged more than 60 and registered ...

The ocean, rich in mineral resources such as oil, natural gas, polymetallic nodules, cobalt-rich ferromanganese crusts, polymetallic sulfides, and rare earth ore, plays an increasingly important role in resource development and economic growth. It is also regarded as an essential strategic space for sustainable development with abundant wind, wave, tidal, and solar energy. Compared with onshore structures, however, offshore structures, being complex, bulky, and expensive, have to endure various random loads that change over time and space, including wind, waves, currents, tides, sea ice, and even coupled with ...

When college athletes are evaluated for a possible concussion, the diagnosis is based on an athletic trainer or team physician’s assessment of three things: the player’s symptoms, physical balance and cognitive skills.  Research published today suggests that almost half of athletes who are ultimately diagnosed with a concussion will test normally on the recommended cognitive-skills test.  “If you don’t do well on the cognitive exam, it suggests you have a concussion. But many people who are concussed do fine on the exam,” said Dr. Kimberly Harmon, the study’s lead author. She is a professor of family medicine ...

As long as humans have been traveling into space, astronauts have experienced significant health effects from the extreme conditions of space flight, notably the reduction of gravity. Two Buck scientists led a team that has revealed for the first time how the lack of gravity affects the cells of the immune system at single cell resolution. As co-senior authors, along with Christopher E. Mason, PhD of Weill Cornell Medical College, Associate Professor David Furman, PhD and Associate Professor Daniel Winer, MD, published in the ...

Food insecurity, low household income and not having private health insurance are associated with higher rates of prediabetes in adolescents, independent of race and ethnicity, according to a new JAMA Network Open study by University of Pittsburgh and UPMC researchers. The findings suggest that screening for social determinants of health — the non-medical factors that influence a person's health and risk of disease — may help identify youth at risk of prediabetes, which could ultimately improve early interventions that prevent progression to type 2 diabetes. “This study underscores the importance ...

The agility with which humans and animals move is an evolutionary marvel that no robot has yet been able to closely emulate. To help probe the mystery of how brains control movement, Harvard neuroscientists have created a virtual rat with an artificial brain that can move around just like a real rodent.   Bence Ölveczky, professor in the Department of Organismic and Evolutionary Biology, led a group of researchers who collaborated with scientists at Google’s DeepMind AI lab to build a biomechanically realistic digital model of a rat. Using high-resolution data recorded from ...

Scientists unlock secrets of how the third form of life makes energy. An international scientific team has redefined our understanding of archaea, a microbial ancestor to humans from two billion years ago, by showing how they use hydrogen gas.  The findings, published today in Cell, explain how these tiny lifeforms make energy by consuming and producing hydrogen. This simple but dependable strategy has allowed them to thrive in some of Earth’s most hostile environments for billions of years. The paper, led by Monash University Biomedicine Discovery Institute scientists, including ...

The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardise any mission to Mars, according to a new study led by researchers from UCL. The study, published in Nature Communications, is the largest analysis of kidney health in space flight to date and includes the first health dataset for commercial astronauts. It is published as part of a Nature special collection of papers on space and health. Researchers have known that space flight causes certain health issues since the 1970s, in the ...

Depressive symptoms are linked to subsequent memory decline in older people, while poorer memory is also linked to an increase in depressive symptoms later on, according to a new study led by researchers at UCL and Brighton and Sussex Medical School. The study, published in JAMA Network Open, looked at 16 years of longitudinal data from 8,268 adults in England with an average age of 64. The researchers concluded that depression and memory were closely interrelated, with both seeming to affect each other. Senior author Dr Dorina Cadar, of the UCL Department of Behavioural Science & Health and Brighton and Sussex Medical School, said: “It is ...

Quantum computers have the potential to solve complex problems in human health, drug discovery, and artificial intelligence millions of times faster than some of the world’s fastest supercomputers. A network of quantum computers could advance these discoveries even faster. But before that can happen, the computer industry will need a reliable way to string together billions of qubits – or quantum bits – with atomic precision.  Connecting qubits, however, has been challenging for the research community. Some methods form qubits by placing ...

WASHINGTON, June 11, 2024 – Today’s intelligent robots can accurately recognize many objects through vision and touch. Tactile information, obtained through sensors, along with machine learning algorithms, enables robots to identify objects previously handled. However, sensing is often confused when presented with objects similar in size and shape, or objects unknown to the robot. Other factors restrictive to robot perception include background noise and the same type of object with different shapes and sizes. In Applied Physics Reviews, by AIP Publishing, researchers from Tsinghua University worked to break through the difficulties ...

Researchers from Japan uncover the genetic diversity and regional patterns of CARD9 deficiency in patients susceptible to fungal diseases Tokyo, Japan – Fungal infections pose life-threatening risks, especially when vital organs or the central nervous system are affected. Individuals harboring variants in the CARD9 gene are particularly susceptible to invasive fungal infections, given that the protein coded by this gene serves as a critical regulator of the immune system. A recent discovery ...

When the COVID-19 pandemic hit, it sent shock waves across global supply chains. But manufacturers and other businesses weren’t the only ones hit hard: local and international aid organizations, tasked with providing humanitarian assistance during times of crisis, suddenly had a major crisis of their own. How would they get the supplies they needed to carry out their crucial work? According to a new study by the UBC Sauder School of Business, the organizations showed remarkable nimbleness and ingenuity — and while the pandemic was an unusual event, their approaches can provide powerful insights ...

Fukuoka, Japan—Researchers from Kyushu University have uncovered new variations to a traditional illusion, based on how we perceive the motion of flashing lights. Published on May 21 in i-Perception, the findings show that when three light flashes are presented in rapid succession in our side vision, our brain tends to perceive them in a straight line, with the second flash around the midpoint, no matter the actual location of the second flash. This research, which earned the journal’s Early Career Best Paper Prize this year, offers new perspectives on perceptual errors ...

Tsukuba, Japan—Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat. However, the genome of actinomycetes contains a highly conserved gene set encoding virus-like nanoparticles, although its biological significance has remained unclear. In this study, researchers examined Streptomyces davawensis, an actinomycete species, and discovered that it produces virus-like particles that facilitate host reproduction. Extracellular DNA, which serves as a scaffold for multicellular organization, was significantly reduced in the colonies of mutant S. davawensis strains ...

TORONTO, ON, June 11, 2024 — What scientists previously thought about where Fast Radio Bursts (FRBs) come from is just the tip of the iceberg, according to new research led by astronomers at the University of Toronto. The mysteries of the millisecond-long cosmic explosions are unfolding with a new way of analyzing data from the Canadian Hydrogen Intensity Mapping Experiment (CHIME). Published today in The Astrophysical Journal, the study details the properties of polarized light from 128 non-repeating FRBs — those from sources that have ...

WASHINGTON, June 11, 2024 — Journalists who register for the fall meeting of the American Chemical Society (ACS) will have access to about 10,000 presentations on topics including agriculture and food, energy and fuels, health and medicine, sustainability, and more. ACS Fall 2024 is a hybrid meeting being held virtually and in person in Denver on Aug. 18-22, with the theme “Elevating Chemistry.” ACS considers requests for press credentials and complimentary meeting registration from reporters (staff and freelance) and public information officers at government, nonprofit and educational institutions. Please ...