HOUSTON — It's been a burning question in melanoma research: Tumor cells are full of ultraviolet (UV)-induced genetic damage caused by sunlight exposure, but which mutations drive this cancer? None have been conclusively tied to melanoma. The sheer abundance of these passenger mutations has obscured the search for genetic driver mutations that actually matter in melanoma development and progression. By creating a method to spot the drivers in a sea of passengers, scientists at the Broad Institute of MIT and Harvard, the Dana-Farber Cancer Institute and The University ...

The benefits of flirtation in negotiation Does flirtation help or hurt a woman negotiating? According to new research, it helps – creating better economic outcomes for the female negotiators, if the flirtatiousness is perceived as above and beyond friendliness. The study examined "feminine charm" in negotiations through four different experiments, looking at the balance between friendliness and flirtatiousness. Flirtation as opposed to friendliness, the research found, signals self-interest and competitiveness. "Feminine Charm: An Experimental Analysis of its Costs and ...

Bethesda, MD—Pregnant mice exposed to high levels of air pollution gave birth to offspring with a significantly higher rate of obesity and insulin resistance in adulthood than those that were not exposed to air pollution. This effect seemed especially prevalent in male mice, which were heavier regardless of diet. These findings, published online in the FASEB Journal, suggests a link between diesel exhaust exposure in utero and bulging waistlines in adulthood. "It is becoming clearer that our environment profoundly affects our health in ways that are little understood," ...

A Simon Fraser University fish-population statistician, working in collaboration with non-government organization scientists, has uncovered evidence of a potentially deadly virus in a freshwater sport fish in B.C. SFU professor Rick Routledge and Stan Proboszcz, a fisheries biologist at the Watershed Watch Salmon Society, have found evidence of the piscine reovirus (PRV) in cutthroat trout caught in Cultus Lake, in the Fraser Valley region of B.C. Tests conducted by, Fred Kibenge, a virology professor at the Atlantic Veterinary College in Prince Edward Island, found ...

Mathematicians at UC Davis have come up with a new way to crinkle up the fabric of space-time -- at least in theory. "We show that space-time cannot be locally flat at a point where two shock waves collide," said Blake Temple, professor of mathematics at UC Davis. "This is a new kind of singularity in general relativity." The results are reported in two papers by Temple with graduate students Moritz Reintjes and Zeke Vogler, respectively, both published in the journal Proceedings of the Royal Society A. Einstein's theory of general relativity explains gravity as a ...

Athens, Ga. – Using nanoscale materials, researchers at the University of Georgia have developed a single-step method to rapidly and accurately detect viruses, bacteria and chemical contaminants. In a series of studies, the scientists were able to detect compounds such as lactic acid and the protein albumin in highly diluted samples and in mixtures that included dyes and other chemicals. Their results suggest that the same system could be used to detect pathogens and contaminants in biological mixtures such as food, blood, saliva and urine. "The results are unambiguous ...

JUPITER, FL, July 19, 2012 – A new study by scientists on the Florida campus of The Scripps Research Institute shows, in cell culture, a natural compound can virtually eliminate human immunodeficiency virus (HIV) in infected cells. The compound defines a novel class of HIV anti-viral drugs endowed with the capacity to repress viral replication in acutely and chronically infected cells. The HIV/AIDS pandemic continues to affect 34 million individuals worldwide, including more than 3 million children, according to the World Health Organization. Current treatment involves ...

PASADENA, Calif.—The powerful magnitude-8.6 earthquake that shook Sumatra on April 11, 2012, was a seismic standout for many reasons, not the least of which is that it was larger than scientists thought an earthquake of its type could ever be. Now, researchers from the California Institute of Technology (Caltech) report on their findings from the first high-resolution observations of the underwater temblor, they point out that the earthquake was also unusually complex—rupturing along multiple faults that lie at nearly right angles to one another, as though racing through ...

CHICAGO --- When a farmer or rancher is injured on the job, there's an 11 percent chance that an amputation will occur. That's two and a half times more likely than in any other industry. Most of these amputations involve fingers or toes. But the artificial hands, arms, legs, feet and other prostheses used by agricultural workers with a major limb amputation don't seem to be durable, affordable or adaptable enough for their lifestyles, according to a new Northwestern Medicine study. Published online in the journal Disability and Rehabilitation: Assistive Technology, ...

A coat of a certain color could be costly for wild boars, according to research published in the journal Physiological and Biochemical Zoology. The research, led by Ismael Galván of Spain's Museo Nacional de Ciencias Naturales, found that boars with more reddish hair tend to have higher levels of oxidative stress—damage that occurs as toxins from cell respiration build up. The reason for this, the researchers suggest, is that the process of producing reddish pigment eats up a valuable antioxidant that would otherwise be fighting the free radicals that lead to oxidative ...

A sobering new study by researchers from the University of Southern California Davis School of Gerontology finds that elder abuse in low-income Latino communities goes largely unreported. More than 40 percent of Latino elders told Spanish-speaking interviewers that they had been abused or neglected in the last year — yet only 1.5 percent of victims said they had ever reported the abuse to authorities. "Our study has revealed a much higher rate of elder abuse among the Latino community than had been previously thought," said Marguerite DeLiema of the USC Davis School of ...

The end of AIDS is within our reach. But as the authors of a new special supplement in the August, 2012 Journal of Acquired Immune Deficiencies (JAIDS) point out, new financial investments – and renewed commitments – from countries around the world will be critical to fully implement proven treatment and prevention tools already at hand and to continue essential scientific research. "Only then will an AIDS-free generation be possible," write the supplement's editors -- Richard Marlink, Wafaa El-Sadr, Mariangela Simao and Elly Katabira – in their introduction. ** "Are ...

A new experiment conducted at the Joint Quantum Institute (JQI)* examines the relationship between quantum coherence, an important aspect of certain materials kept at low temperature, and the imperfections in those materials. These findings should be useful in forging a better understanding of disorder, and in turn in developing better quantum-based devices, such as superconducting magnets. Most things in nature are imperfect at some level. Fortunately, imperfections---a departure, say, from an orderly array of atoms in a crystalline solid---are often ...

An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria. Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry. Tropical malaria is responsible for more than 1.2 million deaths annually. Severe forms of the disease are mainly caused by the parasite ...

Tampa, Fla. (July 19, 2012) – A study comparing whether endothelial colony-forming cells (ECFCs) derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ECFCs derived from human placenta are more vasculogenic. The study, carried out by researchers at the Indiana School of Medicine, is published in a recent issue of Cell Medicine [2(3)] and is freely available on-line at: http://www.ingentaconnect.com/content/cog/cm. "Circulating ECFCs isolated from umbilical cord blood ...

It doesn't matter what we've experienced – whether it's the breathtaking scope of the Grand Canyon, the ethereal beauty of the Aurora Borealis, or the exhilarating view from the top of the Eiffel Tower – at some point in our lives we've all had the feeling of being in a complete and overwhelming sense of awe. Awe seems to be a universal emotion, but it has been largely neglected by scientists—until now. Psychological scientists Melanie Rudd and Jennifer Aaker of Stanford University Graduate School of Business and Kathleen Vohs of the University of Minnesota Carlson ...

A crucial, and often underappreciated, facet of science lies in deciding how to turn the raw numbers of data into useful, understandable information – often through graphs and images. Such visualization techniques are needed for everything from making a map of planetary orbits based on nightly measurements of where they are in the sky to colorizing normally invisible light such as X-rays to produce "images" of the sun. More information, of course, requires more complex visualizations and occasionally such images are not just informative, but beautiful too. Such is the ...

NASA will launch an inflatable aeroshell/heat shield technology demonstrator on a Black Brant XI sounding rocket July 22 from the agency's launch range at the Wallops Flight Facility in Virginia. The Inflatable Reentry Vehicle Experiment (IRVE-3) is the third in a series of suborbital flight tests of this new technology. Technicians will vacuum pack the uninflated 10-foot (3.05 meters) diameter cone of high-tech inner tubes into a 22-inch (56 centimeters) diameter sounding rocket. During the flight test an on board system will inflate the tubes -- stretching a thermal ...

Tropical Depression Khanun came ashore with some heavy rainfall in the morning hours (local time) on Thursday, July 19. NASA's Terra satellite captured an image of Khanun's clouds on July 19, covering all of South Korea like a blanket. The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument onboard NASA's Terra satellite captured a true-color image of Tropical Depression Khanun over South Korea on July 19, 2012 at 0225 UTC, or 11:25 a.m. local time, Seoul (10:25 p.m. EDT/U.S. on July 18). The last advisory on Khanun from the Joint Typhoon Warning Center ...

Vitamin D deficiency is associated with worse lung function and more rapid decline in lung function over time in smokers, suggesting that vitamin D may have a protective effect against the effects of smoking on lung function, according to a new study from researchers in Boston. "We examined the relationship between vitamin D deficiency, smoking, lung function, and the rate of lung function decline over a 20 year period in a cohort of 626 adult white men from the Normative Aging Study," said lead author Nancy E. Lange, MD, MPH, of the Channing Laboratory, Brigham and ...

Continuous positive airway pressure (CPAP), well established as an effective treatment for severe obstructive sleep apnea (OSA), is also effective in patients with mild and moderately severe OSA and daytime sleepiness, according to a new study. "The evidence for the efficacy of CPAP in patients with milder OSA is limited and conflicting," said lead author Terri E. Weaver, PhD, RN, professor and dean of the University of Illinois at Chicago College of Nursing. "Our multi-site, double-blind, randomized trial, the first placebo-controlled study to use sham CPAP in sleepy ...

NEW BRUNSWICK, N.J. – Poor mothers are more likely to be classified as having the mental illness known as generalized anxiety disorder (GAD) because they live in poverty – not because they are suffering from a psychiatric disorder, according to Rutgers researchers. Judith C. Baer, an associate professor in the School of Social Work, and her team, in the study, "Is it Generalized Anxiety Disorder or Poverty? An Examination of Poor Mothers and Their Children," published online in Child and Adolescent Social Work, argue that although high levels of stress over long periods ...

Racially diverse suburbs are growing faster than white suburbs, but resegregation threatens their prosperity and stability, according to a study entitled, "America's Racially Diverse Suburbs: Opportunities and Challenges," released this week by the Institute on Metropolitan Opportunity at the University of Minnesota Law School. Long perceived as predominantly prosperous white enclaves, suburbs are now at the cutting edge of racial, ethnic and political change in America. The study finds the number of racially diverse suburbs, municipalities ranging from 20-60 percent ...

As more people struggle to afford food, housing, transportation and medical care, one company has introduced a unique solution for the rising cost of living in America. The founders of A Better Life announced today the release of its initial website, http://www.abetterlifeThailand.com, aimed at people wanting to live a better life, by helping them relocate to exotic Thailand. Entrepreneurs David Yow and Gary Orman saw a need in the marketplace for a turnkey solution where they help people to visit or relocate to Thailand because of its luxurious yet affordable lifestyle, ...

The new SL has been produced for the first time almost entirely from aluminium and weighs up to 140 kilograms less than its predecessor. Its highly rigid all-aluminium bodyshell provides the basis for agile, sporty handling that has been taken to an entirely new level, coupled with exemplary roll characteristics and ride comfort. Even better driving dynamics come courtesy of the new BlueDIRECT engines; they are more powerful yet at the same time up to 29 percent more economical than the engines in the outgoing generation. Other new features include the unique Frontbass ...