Similar to DNA microarrays, protein microarray (also known as protein chip) is another strategy for the large-scale study of proteins. It is a high-throughput method used to track the interactions and activities of proteins and to determine their functions in a parallel way. It may consist of a support surface such as a glass slide, nitrocellulose membrane, bead, or microtitre plate, to which an array of capture proteins is bound. Various types of probe molecules may be added to the array and assayed for ability to bind or react with the protein. Typically the probe molecules ...

Dr. Laila Rizvi, Orlando dentist, is asking her patients to leave online reviews of her practice. He hopes that the patient reviews will help increase her practice's online presence and help to encourage others to visit her practice for the first time. "I hope that many of our patients will leave reviews of their experience at our practice online. I believe that we offer a great level of service at our practice and that our patients will have a positive experience here. I'd like to encourage all of our patients that come in to our practice to take a few minutes ...

Dr. Lawrence Rieck, Grandville dentist, is celebrating the fact that he has been practicing from the same location in Grandville for the past 12 years. Dr. Rieck has thoroughly enjoyed his time serving the Grandville community and looks forward to many more successful years of doing so. "I am very happy that I have been able to provide dental services in Grandville for the past 12 years out of the same office. I enjoy coming into work every day because I love interacting with the people that come into my office. I'm looking forward to many more years of serving ...

FootCare Specialists, Inc. offers two convenient office locations in California - Half Moon Bay and San Mateo. Each office location is conveniently located in order to provide patients in their local communities with the best foot and ankle care possible. Dr. David Kaplan, podiatrist in San Mateo, invites each of his patients-new and current-to visit the office that is most convenient for their foot and ankle health care whenever a problem arises. "It is important that our patients get the best care possible and our multiple locations allow us to do just that. ...

Expert orthodontist Dr. Don Jorgensen of Jorgensen Orthodontics announced his practice's new website at www.doctorj.com. Located in Fort Collins, Colorado, Jorgensen Orthodontics offers the latest in orthodontic care including Invisalign: the "Clear" alternative to braces. Jorgensen Orthodontics also offers Invisalign Teen, clear braces, and metal braces. The new website intended for orthodontic patients in Fort Collins and Windsor, Colorado as well as Cheyenne, Wyoming is designed to improve the orthodontic patient experience. Visitors to the site will ...

California State University San Marcos (CSUSM) today announced that the second class of its Environmental Leadership Academy will graduate on Dec. 7, 2012. Each academy session features guest speakers covering current topics like climate change, air pollution, land use change, endangered species and water quality. The class encompasses four weekday sessions, each two days in length. The program was created by the university to educate leaders about the many environmental issues impacting our Southern California region. It is designed to help community, state and business ...

Time to Sign Sports continues its incredible success stories with the announcement that three pitchers will continue their baseball careers at the college level. Sam Ackerman, a right hand pitcher from Montclair, New Jersey will continue his baseball career at the school he always set as his goal. According to Gary Cohn, Time to Sign Sports co-founder, "From day one, Sam had a fascination of playing ball and attending GW. Now, he not only gets to live out that dream, but we believe he will make an impact as a Freshman." Ackerman had several other opportunities ...

On November 9, a Federal judge gave preliminary approval to a credit card class-action settlement agreement between several million merchants, and credit card giants Visa and MasterCard. The lawsuit alleged the credit card companies and certain banks were fixing the rates of swipe fees - the fee a credit card company charges a merchant when a customer uses a card. The settlement received preliminary approval from US District Judge John Gleeson earlier this month in Brooklyn, NY. This approval allows the plaintiffs in the lawsuit to begin registering the merchants who ...

TheDayGroup.net, an internet and technology advisory firm in Greenwich, CT, releases its official commentary on the general lack of marketing funds available for the smart phone platform. As most companies begin to undergo a shift in marketing focus from traditional media and online media to smart phone platforms, many more companies are struggling. "We' ve done our research," commented a spokesperson for TheDayGroup.net, "and we've found that the mobile marketing departments at many corporations are quite starved. You would think that these companies ...

The causes underlying the development of certain types of common cancers have not yet been elucidated. In order to better determine the origin and the sequence of events responsible for the onset of colon cancer, the teams led by Thanos Halazonetis and Stylianos Antonarakis, professors at the University of Geneva (UNIGE), Switzerland, have sequenced the DNA of biopsied tissue from colon polyps. The results show that these precancerous lesions have a specific profile called 'mutator', which is associated with an increased frequency of acquisition of certain mutations. The ...

Everyone knows that men and women tend to hold different views on certain things. However, new research by scientists from the University of Bristol and published in PLoS ONE indicates that this may literally be the case. Researchers examined where men and women looked while viewing still images from films and pieces of art. They found that while women made fewer eye movements than men, those they did make were longer and to more varied locations. These differences were largest when viewing images of people. With photos of heterosexual couples, both men and women ...

Tropical storms that make their way into the North Atlantic, and possibly strike the East Coast of the United States, likely will become more intense during the rest of this century. That's the prediction of one University of Iowa researcher and his colleague as published in an early online release in the prestigious Journal of Climate, the official publication of the American Meteorological Society. The study is a compilation of results from some of the best available computer models of climate, according to lead author Gabriele Villarini, assistant professor of civil ...

BETHESDA, MD – November 30, 2012 -- Using genetic analyses, scientists have discovered that Northern European populations—including British, Scandinavians, French, and some Eastern Europeans—descend from a mixture of two very different ancestral populations, and one of these populations is related to Native Americans. This discovery helps fill gaps in scientific understanding of both Native American and Northern European ancestry, while providing an explanation for some genetic similarities among what would otherwise seem to be very divergent groups. This research was published ...

West Nile virus, Lyme disease, dengue fever, and plague are examples of "vector-borne zoonotic diseases," caused by pathogens that naturally infect wildlife and are transmitted to humans by vectors such as mosquitoes or ticks. According to Marm Kilpatrick, who studies the ecology of infectious diseases at the University of California, Santa Cruz, a broad range of human activities can affect the spread of zoonotic diseases. In an article in the December 1 issue of the British medical journal Lancet, Kilpatrick and coauthor Sarah Randolph of the University of Oxford describe ...

Researchers funded by the National Science Foundation (NSF) describe in a new publication a viable community of bacteria that ekes out a living in a dark, salty and subfreezing environment beneath nearly 20 meters of ice in one of Antarctica's most isolated lakes. The finding could have implications for the discovery of life in other extreme environments, including elsewhere in the solar system. If, as the researchers postulate, the bacteria survive purely from chemical reactions, as opposed to drawing energy from the sun or other sources, "this gives us an entirely ...

Two new studies appearing in the Journals of Gerontology Series A: Biological Sciences and Medical Sciences show that vitamin D may be a vital component for the cognitive health of women as they age. Higher vitamin D dietary intake is associated with a lower risk of developing Alzheimer's disease, according to research conducted by a team led by Cedric Annweiler, MD, PhD, at the Angers University Hospital in France. Similarly, investigators led by Yelena Slinin, MD, MS, at the VA Medical Center in Minneapolis found that low vitamin D levels among older women are associated ...

Developers of renewable energy and shale gas must overcome fundamental geological and environmental challenges if these promising energy sources are to reach their full potential, according to a trio of leading geoscientists. Their findings will be presented on Dec. 4, at 5:15 p.m. (PT), at the fall meeting of the American Geophysical Union (AGU) in San Francisco in Room 102 of Moscone Center West . "There is a critical need for scientists to address basic questions that have hindered the development of emerging energy resources, including geothermal, wind, solar and ...

Bopha intensified into a typhoon today, Nov. 30, as it continues to affect the islands in Micronesia in the western North Pacific Ocean. NASA's TRMM satellite captured rainfall data of Bopha and noticed "Hot Tower" thunderstorms as it was intensifying from a tropical storm into a typhoon. When NASA and the Japanese Space Agency's Tropical Rainfall Measuring Mission (TRMM) satellite passed over Bopha twice on Nov. 29, and the later data showed that the area of heaviest rainfall had expanded and was still south of the center of circulation. The heaviest rainfall was occurring ...

Human activities are advancing the spread of vector-borne, zoonotic diseases such as West Nile virus, Lyme disease and dengue fever, report scientists publishing a series of papers today in the journal The Lancet. Vector-borne zoonotic diseases result from disease-causing agents or pathogens that naturally infect wildlife, and are transmitted to humans by carriers such as mosquitoes and ticks. In short, they're diseases transmitted between animals and humans. Widespread land-use change, globalization of trade and travel, and social upheaval are driving the emergence ...

Turning lignin, a plant's structural "glue" and a byproduct of the paper and pulp industry, into something considerably more valuable is driving a research effort headed by Amit Naskar of Oak Ridge National Laboratory. In a cover article published in Green Chemistry, the research team describes a process that ultimately transforms the lignin byproduct into a thermoplastic – a polymer that becomes pliable above a specific temperature. Researchers accomplished this by reconstructing larger lignin molecules either through a chemical reaction with formaldehyde or by washing ...

Cyber attacks that have long caused major work disruption and theft of private information are becoming more sophisticated with prolonged attacks perpetrated by organized groups. In September 2012, Bank of America, Citibank, the New York Stock Exchange, and other financial institutions were targets of attacks for more than five weeks. Defense Secretary Leon E. Panetta warned that the United States was facing the possibility of a "cyber-Pearl Harbor" and was increasingly vulnerable to foreign computer hackers who could disrupt the government, utility, transportation, and ...

The 2012 Atlantic Hurricane season was a busy one as there were 19 tropical cyclones. A new NASA animation using data from the Tropical Rainfall Measuring Mission satellite known as TRMM shows rainfall from tropical cyclones in the western Atlantic, as measured from space. The TRMM satellite has now been making highly accurate measurements of rainfall from space for fifteen years since it launched in Nov. 1997. TRMM is a joint mission between NASA and the Japanese space agency, JAXA. TRMM can be used to calibrate rainfall estimates from other satellites. Those rainfall ...

Researchers at the University of California, San Diego School of Medicine and the VA San Diego Healthcare System have found that deficiencies in the neural processing of simple auditory tones can evolve into a cascade of dysfunctional information processing across wide swaths of the brain in patients with schizophrenia. The findings are published in the current online edition of the journal Neuroimage. Schizophrenia is a mental disorder characterized by disturbed thought processes and difficulty in discerning real from unreal perceptions. Common symptoms include auditory ...

DETROIT – Postmenopausal women suffered significant bone density loss in their hip after they were treated with an epidural steroid injection for back pain relief, according to a Henry Ford Hospital study Bone density loss after six months was six times greater when compared to the typical bone density loss seen in a year in a postmenopausal woman who doesn't receive steroid injection, researchers say. Shlomo Mandel, M.D., a Henry Ford orthopedic physician and the study's lead author, says physicians should exercise caution prescribing an epidural steroid for select ...

The central skill of cancer is its ability to mutate – that's how it became cancerous in the first place. Once it's started down that path, it's not so difficult for a cancer cell to mutate again and again. This means that different tumors within a single patient or even different areas within the same cancerous deposit may develop different genetic characteristics. This heterogeneity helps cancer escape control by new, targeted cancer therapy drugs. Two of these targeted drugs are crizotinib and erlotinib – they do wonders for the patients whose cancers depend on the ...