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Computerized osteoporosis detection

2012-10-01
A computerized approach to examining patient bone X-rays for diagnosis of osteoporosis could side-step the subjectivity associated with visual examination, according to a new research paper in the International Journal of Biomedical Engineering and Technology published in October. Neelesh Kumar of the Central Scientific Instruments Organisation in Chandigarh, India, and colleagues recognized that the bone disorder osteoporosis is on the increase but that diagnosis using X-ray images of the patient's skeleton often lead to false positives and false negatives because visual ...

The chemical memory of seawater

2012-10-01
Water does not forget, says Prof. Boris Koch, a chemist at the Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Association. Irrespective of what happens in the sea: whether the sun shines, algae bloom or a school of dolphins swims through a marine area – everything and everyone leaves biomolecular tracks. With the help of a combination of new techniques, Boris Koch and colleagues can now identify and retrace some of these. In a special volume of the open access journal Biogeosciences, these scientists report on how these analyses work and which ...

First images of Landau levels revealed

First images of Landau levels revealed
2012-10-01
Physicists have directly imaged Landau Levels – the quantum levels that determine electron behaviour in a strong magnetic field – for the first time since they were theoretically conceived of by Nobel prize winner Lev Landau in 1930. Using scanning tunnelling spectroscopy - a spatially resolved probe that interacts directly with the electrons - scientists at institutions including the University of Warwick and Tohoku University have revealed the internal ring-like structure of these Landau Levels at the surface of a semiconductor. The experimental challenge in the work ...

UK-led project unravels the structures of membrane proteins

2012-10-01
The European Drug Initiative on Channels and Transporters (EDICT), which comes to an end this year, focused on membrane proteins. They make up a third of all proteins in every organism and play a key role in many human diseases. Membrane proteins are difficult to study and poorly understood, but the four-year EDICT project has enabled a major step forward in our understanding of the structures – and even more importantly the functions – of over 30 of these proteins. Bringing together over 100 researchers across 12 countries, the project has developed better and faster ...

'Green Brain' project to create an autonomous flying robot with a honey bee brain

2012-10-01
Scientists at the Universities of Sheffield and Sussex are embarking on an ambitious project to produce the first accurate computer models of a honey bee brain in a bid to advance our understanding of Artificial Intelligence (AI), and how animals think. The team will build models of the systems in the brain that govern a honey bee's vision and sense of smell. Using this information, the researchers aim to create the first flying robot able to sense and act as autonomously as a bee, rather than just carry out a pre-programmed set of instructions. If successful, this ...

Yearlong MAGIC climate study launches

2012-10-01
UPTON, NY - A Horizon Lines container ship outfitted with meteorological and atmospheric instruments installed by U.S. Department of Energy (DOE) scientists from Argonne National Laboratory and Brookhaven National Laboratory will begin taking data today for a yearlong mission aimed at improving the representation of clouds in climate models. The study, a collaborative effort between DOE's Atmospheric Radiation Measurement (ARM) program Climate Research Facility and Horizon Lines, marks the first official marine deployment of the second ARM Mobile Facility, AMF2, and is ...

Nothing to sneeze at: Scientists find cheating ragweed behaves better with its kin

2012-10-01
Cheating. Conflict. Competition. It may sound like a soap opera but this is the complex life of the despised ragweed plant. And in the highly competitive fight for nutrients, researchers have found ragweed will behave altruistically with its siblings, investing precious resources for the benefit of the group. A growing body of work suggests plants recognize and respond to the presence and identity of their neighbours and the findings, published online in the journal PLOS ONE, provide further evidence of the importance of family in preserving cooperation within and ...

Evidence-based guidelines enable optimal treatment of common low-back pain

Evidence-based guidelines enable optimal treatment of common low-back pain
2012-10-01
AUGUSTA, Ga. – While scientific evidence suggests that less is typically more when it comes to diagnosing and treating low-back pain in the U.S., the number of expensive imaging exams and surgeries done on patients continues to rise, researchers say. More than 25 percent of American adults report at least one episode of acute low-back pain in the past three months and the annual total price tag is about $100 billion, according to a study in an issue of the Journal of the American College of Radiology focusing on health care reform. "For the great majority of patients, ...

Longest fiber-optic sensor network developed

Longest fiber-optic sensor network developed
2012-10-01
This press release is available in Spanish.Montserrat Fernández-Vallejo, a telecommunications engineer and graduate of the UPNA-Public University of Navarre, has experimentally developed various fibre-optic sensor networks for the remote monitoring of large infrastructures. Specifically, she has managed to develop the largest network so far in existence —measuring 250 km—, which is equipped with a multiplexing capability, (which enables two or more information channels to be combined within a single transmission medium). This technological development in the field of ...

EARTH: Risky business: Modeling catastrophes

2012-10-01
Alexandria, VA – The probability that a given natural hazard could become a natural disaster is higher today than at any previous point in history, largely because of population growth putting more people and infrastructure in harm's way. Who pays for the damage and how is value and risk assessed? Much of it comes down to insurance and reinsurance agencies, which are relying more and more on sophisticated catastrophe modeling tools to help gauge when the next disaster will strike, and how much it will cost. Catastrophe modeling has only been around for a couple of decades, ...

Baby communication gives clues to autism

2012-10-01
CORAL GABLES, FL -- Approximately 19 percent of children with a sibling diagnosed with Autism Spectrum Disorder (ASD) will develop Autism due to shared genetic and environmental vulnerabilities, according to previous studies. For that reason, University of Miami (UM) psychologists are developing ways to predict the occurrence of ASD in high-risk children, early in life, in hopes that early intervention will lead to better outcomes in the future. Their findings are published in the journal Infancy. The study is one of the first to show that measures of non-verbal communication ...

Eliminating visual clutter helps people with mild cognitive impairment

Eliminating visual clutter helps people with mild cognitive impairment
2012-10-01
A new study from Georgia Tech and the University of Toronto suggests that memory impairments for people diagnosed with early stage Alzheimer's disease may be due, in part, to problems in determining the differences between similar objects. The findings also support growing research indicating that a part of the brain once believed to support memory exclusively – the medial temporal lobe - also plays a role in object perception. The results are published in the October edition of Hippocampus. Mild cognitive impairment (MCI) is a disorder commonly thought to be a precursor ...

Researchers halt autoimmune disease myasthenia gravis in mice

2012-10-01
Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body. The technique, the result of more than 10 years of work, holds promise for a highly specific therapy for the progressively debilitating muscle-weakening human disorder, one that avoids the need for long-term, systemic immunosuppressant drugs that control the disease but may create unwanted side effects. The research, ...

Advance directives: Implementation leaves much to be desired

2012-10-01
Advance directives are not widespread among the elderly. This was revealed by a cross-sectional study of 11 German nursing homes performed by Sarah Sommer and her colleagues and presented in the latest issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2012; 109(37): 577). In the year 2007, only 11% of the nursing home residents had a personally signed advance directive, while a further 1.4% had a proxy directive, i.e., a document signed not by the resident but by a representative. Few of the advance directives made any provision for an acute health crisis. ...

Trapping weevils and saving monarchs

2012-10-01
This press release is available in Spanish.Ensuring the monarch butterfly's survival by saving its milkweed habitat could result from U.S. Department of Agriculture (USDA) studies initially intended to improve detection of boll weevils with pheromone traps. Charles Suh and his colleagues at the Agricultural Research Service (ARS) Areawide Pest Management Research Unit in College Station, Texas, have found a pheromone formula that is attractive to a major milkweed pest, the milkweed stem weevil. The discovery stems from research originally designed to help improve ...

Macrophage accumulation of triglycerides yields insights into atherosclerosis

2012-10-01
Bethesda, MD—A research report appearing in the Journal of Leukocyte Biology helps explain how specific immune cells, called macrophages, accumulate triglycerides to support their function. Because a characteristic finding in atherosclerosis is the accumulation of fat in macrophages in the arterial wall, understanding how macrophages accumulate triglycerides may lead to new approaches toward slowing or stopping the development of atherosclerosis. "Activation of macrophages leads to the accumulation of triglycerides in macrophages by multiple pathways that may have beneficial ...

Genetic activity in the entire genome of multicellular fungi analysed at a stroke

2012-10-01
With a combination of microscopic laser scissors and modern sequencing methods, biologists at the Ruhr-Universität have analyzed the activity of genes in the entire genome of certain fungi in one fell swoop. Especially with organisms in the millimetre size range, it is a particular challenge because little cell material is available. The scientists of the RUB Department of General and Molecular Botany took advantage of the method to investigate the development of small multicellular fungi. The results are reported in the journal BMC Genomics. Gene activity differs from ...

How sexual power can be disempowering

2012-10-01
Gender roles and norms play a key role in sexual behavior between men and women. It is often assumed that men should dominate women sexually. This assumption may lead to loss of both power and the ability to control sexual behavior among women and men, as well as lead to increased sexual risk-taking, such as not using a female condom. The new study, by Dr. Lisa Rosenthal from Yale University in the US, and her colleagues, is published online in Springer's journal Sex Roles. Social dominance orientation is a measure of people's level of support for social power inequalities ...

Study questions association between common heartburn drugs and risk of pneumonia

2012-10-01
Previous studies that have associated the use of proton pump inhibitors (PPI) – which include popular anti-heartburn medications like Prilosec and Nexium – with an increased incidence of pneumonia may not have found a true cause-and-effect relationship. A study that has been released online by the Journal of General Internal Medicine outlines a strategy for determining when the results of such observational studies may have been distorted by unmeasured factors and then finds that may be the case with the association between PPIs and pneumonia risk. "Our study is the ...

PET predicts early response to treatment for head and neck cancer patients

2012-10-01
Reston, Va. (October 1, 2012) – Determining the optimal treatment course and predicting outcomes may get easier in the future for patients with head and neck sqaumous cell carcinomas (HNSCCs) with the use of an investigational imaging agent. Research published in the October issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) imaging with 3'-deoxy-3'F-18-fluorothymidine (18-F-FLT) during treatment and early follow-up has the potential to predict therapeutic responses and identify patients needing close follow-up to detect persistent or ...

Radiology is front and center in health care reform

Radiology is front and center in health care reform
2012-10-01
AUGUSTA, Ga. – While it's leveling off, a decade of increased use of sophisticated, expensive, imaging studies has put radiologists and their specialty front and center in health care reform, says the chair of an academic radiology department. That seemingly dubious distinction gives radiologists the chance to take a leadership role in reducing costs, optimizing utilization and improving patient care, said Dr. James V. Rawson, Chair of the Medical College of Georgia Department of Radiology at Georgia Health Sciences University. Rawson and Dr. Ruth Carlos, Professor ...

Tobacco contains highly toxic compounds not regulated by law

Tobacco contains highly toxic compounds not regulated by law
2012-10-01
Researchers from the University of Alicante (Spain) have analysed ten brands of cigarettes and found that the concentrations of certain harmful and carcinogenic substances vary significantly from one brand to another. Until now legislation has not covered these compounds and only establishes limits for nicotine, tar and carbon monoxide. Scientists have also developed catalysts to reduce the harmful products in tobacco. In accordance with current legislation, cigarette packets indicate the nicotine, tar and carbon monoxide concentrations in order to confirm that these ...

Camels give President Obama's Alzheimer's plan a lift

2012-10-01
Bethesda, MD—President Obama's national plan to fight Alzheimer's disease just got a lift thanks to a team of international researchers whose recent discovery may lead to enhanced imaging of and improved drug delivery to the brain. A research report appearing in The FASEB Journal, describes an entirely new class of antibody discovered in camelids (camels, dromedaries, llamas, and alpacas) that is able to cross the blood-brain barrier, diffuse into brain tissue, and reach specific targets. Having such antibodies, which are naturally available, may be part of a "game changer" ...

Therapeutic time window important factor for cord blood cell transplantation after stoke

2012-10-01
Putnam Valley, NY. (Oct. 1, 2012) – A research team from Germany has found that optimal benefit and functional improvement for ischemic stroke results when human umbilical cord blood mononuclear cells (hUCB MNCs) are transplanted into rat stroke models within 72 hours of the stroke. Their study is published in the current issue of Cell Transplantation (21:6), now freely available on-line at: http://www.ingentaconnect.com/content/cog/ct/. "Ischemic stroke is one of the most frequent causes of death and the most common reason for permanent disabilities in adults in ...

MRI images transplanted islet cells with help of positively charged nanoparticles

2012-10-01
Tampa, Fla. (Oct. 1, 2012) – In a study to investigate the detection by MRI of six kinds of positively-charged magnetic iron oxide nanoparticles designed to help monitor transplanted islet cells, a team of Japanese researchers found that the charged nanoparticles they developed transduced into cells and could be visualized by MRI while three kinds of commercially available nanoparticles used for controls could not. The study is published in a recent special issue of Cell Medicine [3(1)], now freely available on-line at: http://www.ingentaconnect.com/content/cog/cm. "Our ...
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