Lariats: How RNA splicing decisions are made
PROVIDENCE, R.I. [Brown University] — Tiny, transient loops of genetic material, detected and studied by the hundreds for the first time at Brown University, are providing new insights into how the body transcribes DNA and splices (or missplices) those transcripts into the instructions needed for making proteins.
The lasso-shaped genetic snippets — they are called lariats — that the Brown team reports studying in the June 17 edition of Nature Structural & Molecular Biology are byproducts of gene transcription. Until now scientists had found fewer than 100 lariats, mostly ...