The Qing Dynasty in China, after over 250 years, crumbled in 1912. Led by the Complexity Science Hub (CSH), an international research team has pinpointed key reasons behind the collapse, revealing parallels to modern instability and offering vital lessons for the future.   China is considered today to be the world's largest economy (in terms of PPP). However, this position is not new. In 1820, China's economy already held the top spot, accounting for 32.9% of the global GDP. In the interim, there was a period of decline followed by a resurgence. In 1912, after over 250 years in power, the Qing Dynasty collapsed despite being considerably wealthier at the time ...

Scientists from Queen Mary University of London have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. The two genes discovered actively ‘work’ in most human cancer types, meaning the findings could potentially extend to other cancers with elevated levels of the genes. The researchers also looked through a chemical library, commonly used for drug discovery, and found two substances that could target the two genes specifically and make resistant cancer cells almost 30 times more sensitive to ...

Digital information exchange can be safer, cheaper and more environmentally friendly with the help of a new type of random number generator for encryption developed at Linköping University, Sweden. The researchers behind the study believe that the new technology paves the way for a new type of quantum communication. In an increasingly connected world, cybersecurity is becoming increasingly important to protect not just the individual, but also, for example, national infrastructure and banking systems. And there is an ongoing race between hackers and those trying to protect information. The most common way ...

People living with lung conditions, such as asthma and chronic obstructive pulmonary disease (COPD), face even greater risks from climate change, according to an expert report published today (Monday) in the European Respiratory Journal [1]. The report brings together evidence on how the effects of climate change, such as heatwaves, wildfires and flooding, will exacerbate breathing difficulties for millions of people around the world, particularly babies, young children and the elderly. On behalf of the European Respiratory Society, which represents more than 30,000 lung specialists from 160 countries, the authors ...

ChatGPT could help to increase vaccine uptake by debunking myths around jab safety, say the authors of a study published in the peer-reviewed journal Human Vaccines and Immunotherapeutics. The researchers asked the artificial intelligence (AI) chatbot the top 50 most frequently-asked Covid-19 vaccine questions. They included queries based on myths and fake stories such as the vaccine causing Long Covid. Results show that ChatGPT scored nine out of 10 on average for accuracy. The rest of the time it was correct but left some gaps in the information provided, according to the study. Based on these findings, experts who led the study from the GenPoB research group based ...

Humans, like many other species, regulate protein intake more strongly than any other dietary component and so if protein is diluted there is a compensatory increase in food intake. The hypothesis proposes that the dilution of protein in modern-day diets by fat and carbohydrate-rich processed foods is driving increased energy intake as the body seeks to satisfy its natural protein drive - eating unnecessary calories until it does so. This paper, resulting from the Royal Society Discussion Meeting held in London last October, shows that observational, experimental and mechanistic research increasingly supports ...

For roughly 80% of breast cancer survivors, treatment doesn’t end with surgery, radiation and chemotherapy. Instead, for the next five to 10 years, doctors recommend that they take medication to block sex hormones, which can fuel tumor growth and spark recurrence. The drugs are life-saving: They’ve been shown to cut risk of cancer recurrence by as much as half in patients with hormone receptor-positive tumors (HR+)—the most common form of breast cancer. Yet despite their promised benefits, 40% of patients stop taking them early and a third ...

Micro- and nanodisk lasers have recently emerged as promising optical sources and probes for various applications in the fields of nanophotonics and biomedicine. Their ability to achieve lasing at a deterministic wavelength and ultra-narrowband precision is critical for several applications in on-chip photonic communications, on-chip bioimaging, biochemical sensing, and quantum photonic information processing. However, the large-scale fabrication of such precise wavelength micro- and nanodisk lasers remains challenging. Current nanofabrication processes introduce randomness in ...

For more than 30 years, the models that researchers and government agencies use to forecast earthquake aftershocks have remained largely unchanged. While these older models work well with limited data, they struggle with the huge seismology datasets that are now available. To address this limitation, a team of researchers at the University of California, Santa Cruz and the Technical University of Munich created a new model that uses deep learning to forecast aftershocks: the Recurrent Earthquake foreCAST (RECAST). In a paper published today in Geophysical Research Letters, the scientists show how the deep learning model is more flexible ...

(SACRAMENTO, Calif.) — A team of UC Davis and University of Oxford researchers have developed an innovative tool: SparkMaster 2. The open-source software allows scientists to analyze normal and abnormal calcium signals in cells automatically. Calcium is a key signaling molecule in all cells, including muscles like the heart. The new software enables the automatic analysis of distinct patterns of calcium release in cells. This includes calcium "sparks," microscopic releases of calcium within cardiac cells associated ...

Key takeaways Ants can either forage for food as individuals or recruit other members of their colonies to help search for or carry food back to their nests. UCLA biologists found that the strategies ants use to forage play a bigger role in how they build their nests than innate, evolutionary “blueprints” do. When building nests, ants strike a balance between transportation efficiency and architectural constraints. Researchers say that observation could help humans design more efficient transportation systems tailored to specific needs. Could ants’ nests hold the secret to reducing traffic congestion on the 405 Freeway? In a new study, UCLA biologists ...

UNIVERSITY PARK, Pa. — In 2012, when the spotted lanternfly (Lycorma delicatula) arrived in the U.S. from its home in China, scientists, land managers, and growers were understandably concerned that the sap-feeding insect would damage native and commercial trees. New long-term research led by Penn State has discovered that hardwood trees, such as maple, willow and birch, may be less vulnerable than initially thought. “Since the lanternfly was first introduced to the northeastern U.S., the question has been, ‘How at-risk are our forests?’ said Kelli Hoover, professor of entomology at Penn State. “So far, we haven't had a good answer. Our study is the first ...

EAST LANSING, Mich. – Backed by a $26 million federal grant, researchers at three Michigan universities, a leading health care system, and a state agency will continue a long-term study of how exposure to environmental factors during pregnancy and early childhood can impact health for a lifetime.  The funding from the National Institutes of Health, or NIH, is for the second phase of a national research program called ECHO, which stands for the Environmental Influences on Child Health Outcomes, and includes a sample of mothers, infants and children from across the United States. The first phase began in 2016.  “This award shows the research ...

Milwaukee, Wis. – Sept. 1, 2023 – Despite advances in treatment for high cholesterol, heart disease remains the leading cause of death in the U.S. Scientists at the Medical College of Wisconsin (MCW) are investigating the role of a form of cholesterol called very-low-density lipoprotein – and their findings may lead to new treatment options in the future. The research team is led by Ze Zheng, MBBS, PhD, MCW assistant professor of medicine (endocrinology and molecular medicine); co-leader of the MCW Cardiovascular Center’s Atherosclerosis, Thrombosis ...

A planet about 950 light years from Earth could be the Looney Tunes’ Yosemite Sam equivalent of planets, blowing its atmospheric ‘top’ in spectacular fashion.  The planet called HAT-P-32b is losing so much of its atmospheric helium that the trailing gas tails are among the largest structures yet known of an exoplanet, a planet outside our solar system, according to observations by astronomers.  Three-dimensional (3D) simulations on the Stampede2 supercomputer of the Texas Advanced Computing Center (TACC) helped model the flow of the planet’s atmosphere, ...

Michelle Kidder, a senior R&D staff scientist at the Department of Energy’s Oak Ridge National Laboratory, has received the American Chemical Society’s Energy and Fuels Division’s Mid-Career Award for sustained and distinguished contributions to the field of energy and fuel chemistry. She was recognized for her scientific community service, leadership and contributions. Her research focuses on novel material development, methods and advanced characterizations for the separation and reaction chemistry of renewable energy resources including lignin and carbon dioxide.   Kidder, ...

Subho Mukherjee, an R&D associate in the Vehicle Power Electronics Research group at the Department of Energy’s Oak Ridge National Laboratory, has been elevated to the grade of senior member of the Institute of Electrical and Electronics Engineers, or IEEE. Senior IEEE members have made significant contributions to the profession and worked in the engineering field for 10 years or more. As an electrical engineer, Mukherjee focuses on wireless power charging and developing wide bandgap semiconductor-based ...

Researchers from the Cluster of Excellence Centre for the Advanced Study of Collective Behaviour (CASCB) and the Max Planck Institute of Animal Behavior have converted a former barn into a cutting-edge technology lab for complex behavioral analysis. In it, they can now study the intricate behaviour of animal groups. The barn also served as a prototype for the largest swarm behaviour lab at the University of Konstanz: the Imaging Hangar. A major limitation in behavioural research is that scientists can either study animals under highly-controlled, yet often unrealistically simplified and ...

When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) now discovered that immune cells actively generate their own guidance system to navigate through complex environments. This challenges earlier notions about these movements. The researchers’ findings, published in the journal Science Immunology, enhance our knowledge of the immune system and offer potential new approaches to improve human immune ...

Scientists at CeMM, Max Perutz Labs, and St. Anna Children’s Cancer Research Institute in Vienna have achieved a significant advancement in the research of rare immune system disorders. Through a network-based approach, they have reclassified approximately 200 rare diseases. Initial comparisons with clinical data already demonstrate how this can enhance the prediction of treatment efficacy. Moreover, the study reveals for the first time the strong similarities between the molecular mechanisms of rare diseases and ...

Increased withdrawals of groundwater resources are accelerating groundwater depletion rates in India, a groundwater depletion hotspot, a new study finds. The study, published today in the journal Science Advances, is led by University of Oklahoma Department of Geography and Environmental Sustainability assistant professor Nishan Bhattarai. Bhattarai and his collaborators found that under a business-as-usual scenario of groundwater use for irrigation, warming may triple the groundwater depletion rates. Approximately 60% of India’s irrigated agriculture depends on the threatened groundwater. The results of the study indicate that adaptation ...

EMBARGOED FOR RELEASE AT 2 P.M. ET FRIDAY, SEPT. 1, 2023 Photos ANN ARBOR—A new University of Michigan-led study finds that farmers in India have adapted to warming temperatures by intensifying the withdrawal of groundwater used for irrigation. If the trend continues, the rate of groundwater loss could triple by 2080, further threatening India's food and water security. Reduced water availability in India due to groundwater depletion and climate change could threaten the livelihoods of more than one-third of the country's 1.4 billion ...

SAN ANTONIO (Sept. 1, 2023) — What initiates chemical intolerance (CI)? In a newly released survey of thousands of U.S. adults, respondents most frequently cited exposures to biological sources, such as mold and algae “blooms,” and/or fossil fuels, their combustion products and synthetic chemical derivatives such as pesticides, plastics and persistent organic pollutants.  It's an issue in the news, as toxic mold spawned by the moisture left behind by flood waters from Hurricane ...

East Hanover, NJ – September 1, 2023 – Labor Day weekend brings more good news for people with disabilities, with record-breaking highs for labor force participation and employment-to-population ratio, according to today’s National Trends in Disability Employment – semi-monthly update (nTIDE), issued by Kessler Foundation and the University of New Hampshire’s Institute on Disability (UNH-IOD). In comparison, both indicators declined slightly for people without disabilities.  Month-to-Month nTIDE Numbers (comparing July 2023 to August 2023) Based on data from the U.S. Bureau of Labor Statistics (BLS) Jobs Report released ...

New Haven, Conn. — Health benefits that have resulted from reductions in fine particulate air pollution aren’t distributed equally among populations in the U.S., a new Yale-led study finds. Racial and ethnic minorities — and Black people in particular — still experience disproportionately high rates of cardiovascular disease-related deaths caused by exposure to fine particulate matter, according to the research. The findings were published Aug. 31 in Nature Human Behavior. Fine particulate matter, also known as PM2.5, consists of particles or droplets smaller than 2.5 micrometers in diameter, or ...