London, United Kingdom – 29 Aug 2024: According to research presented at ESC Congress 2024,1 women with endometriosis have a 20% greater risk of significant cardiac outcomes compared with women without endometriosis.   “For decades, cardiovascular disease (CVD) has been thought of as a man’s disease and risk factors have been considered from the male perspective, for example, including erectile dysfunction in guidelines on CVD risk assessment.2 Yet, 1 in 3 women die from CVD and 1 in 10 women suffer from ...

London, United Kingdom – 29 August 2024: The demands of the working week, often influenced by school or work schedules, can lead to sleep disruption and deprivation. However, new research presented at ESC Congress 2024 shows that people that ‘catch up’ on their sleep by sleeping in at weekends may see their risk of heart disease fall by one-fifth.   “Sufficient compensatory sleep is linked to a lower risk of heart disease,” said study co-author Mr Yanjun Song of the State Key Laboratory ...

London, United Kingdom – 29 August 2024: According to research presented today at ESC Congress 2024,1 patients with stable coronary artery disease who quit smoking at any timepoint after their diagnosis reduced their risk of a major event by almost 50%. In contrast, there was minimal impact on cardiovascular risk in patients who reduced their smoking habits.   The international CLARIFY registry (prospeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY ...

Children can work together to reach a target that benefits a whole group even if it is at a personal cost to themselves, a new study has shown. Researchers invited groups of six to 10-year-olds to take part in a game where they were each given containers of water and could decide how much of it to offer into a common pool. If the group contributed a certain amount of water it resulted in benefits for the whole group, but children also obtained benefits for any water they kept.  At the same time, the ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor Akiko Kojima-Yuasa of the Graduate School of Human Life and Ecology and colleagues. Consuming nucleic acids found in food has been shown to boost the immune system and prevent some diseases. The nucleotides and nucleosides that result from digesting the acids are largely responsible for these beneficial effects. Professor ...

AUGUSTA, Ga. (Aug. 29, 2024) – Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer’s disease, and whether it’s the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem. The hormone therapy, androgen deprivation therapy, known as ADT, treats the cancer by reducing testosterone, which the cancer needs to grow. But androgen is a key regulator of amyloid metabolism and when it’s removed from the equation, more amyloid is left to form the plaques that are a hallmark of Alzheimer’s. “We ...

A new study describing how a prehistoric sea cow was preyed upon by not one, but two different carnivores – a crocodilian and a shark – is revealing clues into both the predation patterns of ancient creatures and the wider food chain millions of years ago. Published in the peer-reviewed Journal of Vertebrate Paleontology, the findings mark one of the few examples of a creature being preyed upon by different animals during the Early to Middle Miocene epoch (23 million to 11.6 million years ago). Predation marks in the skull indicate that the dugongine sea cow, ...

By Jerry Grillo The soundtrack of this story begins with a vaguely recognizable and pleasant groove. But if I stop writing and just listen for a second, the music reveals itself completely. In Freddie Hubbard’s comfortable, lilting trumpet solo over Herbie Hancock’s melodic, repetitive piano vamping, I recognize “Cantaloupe Island.” Then, with my fingers again poised at the keyboard, Freddie and Herbie fade into the background, followed by other instrumental music: captivating — but not distracting — sonic nutrition, feeding my concentration and productivity.  Somewhere, I think, Yiren Ren is studying, focused on her ...

There’s an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic resistant bacteria or ‘superbugs’, researchers from Flinders University and SAHMRI warn. A new study published in the well-respected Journal of Infection, explores the link between the widespread use of antibiotics in residential aged care and the resulting antibiotic resistant bacteria in the gut that can be passed on to other residents. “Commonly ...

A recent study has uncovered alarming insights into the dangers posed by fentanyl-contaminated drug supplies in Australia, including a heightened risk of lethal overdose. The study, titled ‘The gear could be cut with fentanyl which is starting to happen more in Australia’: Exploring Overdose Survivors’ Perspectives on Toxic Supply and Safe Consumption, aimed to explore the role of synthetic opioids in overdoses among Queenslanders. Led by Griffith University’s Dr Timothy Piatkowski, Emma Kill and Steph Reeve in partnership with the Queensland ...

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein stability—a crucial factor in ensuring proteins function correctly and do not cause diseases like Alzheimer's. DeepMind’s AlphaFold algorithm, which can accurately predict a protein’s structure from ...

DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand breaks (DSBs) in DNA. To counteract DNA damage, cells engage in DNA repair to preserve genetic integrity and ensure cell survival as failure to repair DSBs has serious health complications like increased risk of cancer. DSBs are repaired by two mechanisms called non-homologous end joining (NHEJ) and homologous recombination (HR). NHEJ is the predominant DNA repair mechanism in human somatic cells and is ...

Fuel cells offer a promising solution for clean energy with advantages over traditional electric power systems, including extended driving range and higher energy density. Despite these benefits, the high costs and durability concerns associated with fuel cell stacks have limited their commercialization. The durability of membrane electrode assemblies (MEAs), a key component of proton exchange membrane fuel cells (PEMFCs), is particularly affected by the frame sealing structure, which is often overlooked in research. The study, conducted by Tiankuo Chu ...

An international group of researchers has developed a novel approach that enhances the efficiency of the oxygen evolution reaction (OER), a key process in renewable energy technologies. By introducing rare earth single atoms into manganese oxide (MnO2), the group successfully modulated oxygen electronic states, leading to unprecedented improvements in OER performance. Their findings were published in the journal Nano Energy on June 10, 2024. Transition-metal-based oxides have been widely explored for their potential as active OER catalysts. However, the capacity of these catalysts is hindered by the adsorbate evolution mechanism, which ...

The concurrency control in deterministic databases, i.e., deterministic concurrency control, ensures that each transaction batch produces a unique result. In this way, replicas can process transactions in batches without communicating with each other to ensure consistency, which is simpler and more efficient than non-deterministic databases in achieving high availability through replication. Early deterministic concurrency control protocols, e.g. Calvin, Bohm, PWV, rely on the prior knowledge of the read-write set, which is impractical in most scenarios. The state-of-the-art Ari breaks this limitation. However, Aria has three issues. First, ...

The National Science Foundation has announced a $22 million grant to establish a “BioFoundry” laboratory for the study of extreme microorganisms with collaborating facilities at UC Riverside, UC Santa Barbara, and Cal Poly Pomona. The BioFoundry for Extreme and Exceptional Fungi, Archaea, and Bacteria, or ExFAB, will focus on developing techniques to learn from nature’s more unusual microorganisms. These microbes are considered “extreme” because they have unusual nutritional requirements, grow at extremely high or low temperatures, or grow without ...

(Santa Barbara, Calif.) — This week, the National Science Foundation announced the award of a six-year, $22M grant to UC Santa Barbara under its biofoundries program for the establishment of the BioFoundry for Extreme and Exceptional Fungi, Archaea and Bacteria (ExFAB), a collaboration led by UC Santa Barbara (UCSB), together with UC Riverside (UCR), and Cal Poly Pomona (CPP). ExFAB establishes the nation’s first biofoundry that focuses on largely untapped and unexplored extreme microbes. UCSB's award is one of only five grants made under NSF's BioFoundry program during this funding cycle, which awarded ...

Misconceptions about dyslexia are held by professionals who assess children for the learning difficulty, according to a new study which calls for evidence-based standardised assessment procedures. The research, led by Durham University, found that almost half of dyslexia professionals in the study believed at least one unproven indicator for dyslexia, which could lead to children being misdiagnosed. In a survey of 275 dyslexia professionals, the most common myth – which is not backed up by solid evidence – was that people with dyslexia read letters in reverse order, believed by 61 per cent of specialists. Just over 30 per cent of professionals also ...

A recently developed block copolymer could help push the limits of integration and miniaturization in semiconductor manufacturing, report scientists in Tokyo Tech and TOK. Chemically tailored for reliable directed self-assembly, the proposed compound can arrange itself into perpendicular lamellar structures whose half-pitch width is less than 10 nanometers, outperforming conventional and widely used block copolymers. Miniaturization is one of the fundamental qualities of modern electronics and is largely responsible for the incredible increments in performance witnessed ...

Researchers at Macquarie University have developed a new way to produce ultraviolet (UV) light sensors, which could lead to more efficient and flexible wearable devices. The study, published in the journal Small in July, shows how acetic acid vapour – essentially vinegar fumes – can rapidly improve the performance of zinc oxide nanoparticle-based sensors without using high-temperatures for processing. Co-author Professor Shujuan Huang, from the School of Engineering at Macquarie University, says: “We found by briefly exposing the sensor to vinegar vapour, adjoining ...

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes might prevent dementia, providing greater benefits with longer treatment, suggests a large study from Korea published by The BMJ today.  As this study was observational, the researchers note that the effect size could have been overestimated and say randomised controlled trials are now needed to confirm these findings. According to the World Health Organization, the number of people with dementia globally is expected to reach 78 million ...

Girls with mental illness or neurodevelopmental conditions are less likely than their peers to be vaccinated with the HPV vaccine that protects against future cervical cancer. This is according to a new registry study from Karolinska Institutet in Sweden published in The Lancet Public Health. The study involved more than 115,000 girls covered by the Swedish school-based human papillomavirus (HPV) vaccination programme. The vaccine, which prevents cervical cancer, among other things, is offered to all children in Sweden and given by school health services. Significant ...

Scientists are on the verge of a cancer breakthrough after working out how the body’s immune system targets cells devastated by the disease. A new study has discovered that our natural killer cells, from the immune system which protect against disease and infections, instinctively recognise and attack a protein that drives cancer growth. The experts say that by hijacking this protein, known as XPO1, they may be able to activate more killer cells to destroy the disease. Scientists from the University of Southampton, working with experts worldwide, led the study and now believe it could offer new ...

Geriatrics experts have long known that collaboration is key to delivering quality, patient-centered care to older adults. That’s why USC’s Interprofessional Education and Collaboration for Geriatrics (IECG) trains up to 150 students annually from seven health professions to teach the importance of teamwork in meeting the complex needs of the elderly. Now, a study published in the Journal of Interprofessional Care highlights the long-term impact of IECG on USC health sciences graduates. Researchers surveyed graduates one to three years after completing IECG to assess how the program influenced their practice. The findings were significant: 81% ...

New Haven, Conn. — More than two decades ago, a research team in the lab of David Hafler, a Yale researcher who at the time was at Harvard, discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an underlying cause of autoimmune disease, specifically multiple sclerosis (MS). For many years, however, the mechanism behind this dysfunction has remained unclear. In a new Yale-led study, a team of researchers finds that this loss of immune regulation is triggered by an increase in PRDM1-S, a protein involved in immune function, ...