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Glowing COVID-19 diagnostic test prototype produces results in one minute

Glowing COVID-19 diagnostic test prototype produces results in one minute
2024-01-17
Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? Now, in ACS Central Science, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research. From fireflies ...

Microplastics from natural fertilizers are blowing in the wind more often than once thought

2024-01-17
Though natural fertilizers made from treated sewage sludge are used to reintroduce nutrients onto agricultural fields, they bring along microplastic pollutants too. And according to a small-scale study published in ACS’ Environmental Science & Technology Letters, more plastic particles get picked up by the wind than once thought. Researchers have discovered that the microplastics are released from fields more easily than similarly sized dust particles, becoming airborne from even a slight breeze. Microplastics, or small bits of plastic less than 5 millimeters long, have appeared everywhere from clouds to heart tissues. And with these plastics’ increasing prevalence in ...

New AI makes better permafrost maps

New AI makes better permafrost maps
2024-01-17
LOS ALAMOS, N.M., Jan. 17, 2024 — New insights from artificial intelligence about permafrost coverage in the Arctic may soon give policy makers and land managers the high-resolution view they need to predict climate-change-driven threats to infrastructure such as oil pipelines, roads and national security facilities. “The Arctic is warming four times faster than the rest of the globe, and permafrost is a component of the Arctic that’s changing really rapidly,” said Evan Thaler, a Chick Keller Postdoctoral Fellow at Los Alamos National Laboratory. Thaler is corresponding ...

New study unveils emotional hubs that exist across languages

New study unveils emotional hubs that exist across languages
2024-01-17
Emotions exert a profound influence on human behavior, prompting extensive explorations in the realms of psychology and linguistics. Understanding central emotions also has practical utility since it can help organizations create messages that resonate better with people. For instance, businesses can enhance their connection with their customers, and non-profits can prompt quicker action by skillfully leveraging the salient emotions in humans. Colexification is a phenomenon in which the occurrence of a single word is associated with multiple concepts that share semantic relationships. The analysis of colexification is an innovative linguistic method for ...

Childhood stress linked to higher risk of high blood pressure, obesity, diabetes in adults

2024-01-17
Research Highlights: Consistently high scores of perceived stress during adolescence through adulthood may contribute to worse cardiometabolic health including obesity in young adults.. Researchers suggest the adoption of healthy coping strategies for stress management early in life may help prevent cardiometabolic diseases, from heart disease to Type 2 diabetes. Embargoed until 4 a.m. CT/5 a.m. ET Wednesday, January 17, 2024 DALLAS, January 17, 2024 — Young adults who reported higher stress during their teenage years to adulthood were more likely to ...

US air pollution rates on the decline but pockets of inequities remain

2024-01-17
Over the last decades, air pollution emissions have decreased substantially; however, the magnitude of the change varies by demographics, according to a new study by Columbia University Mailman School of Public Health. The results indicate there are racial/ethnic and socioeconomic disparities in air pollution emissions reductions, particularly in the industry and energy generation sectors. The findings are published in the journal Nature Communications. The research provides a national investigation of air pollution emission ...

Fly brain, mouse brain, worm brain: They all network the same

Fly brain, mouse brain, worm brain: They all network the same
2024-01-17
New York, January 17, 2024 — In all species, brain function relies on an intricate network of connections that allows neurons to send information back and forth between one another, commanding thought and physical activity. But within those networks a small number of neurons share much stronger connections to one another than all the others. These abnormally strong connections—known as “heavy tailed” based on the shape of their distribution—are thought to play an outsized role in brain function.   Researchers ...

Surprisingly simple model explains how brain cells organize and connect

2024-01-17
A new study by physicists and neuroscientists from the University of Chicago, Harvard and Yale describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism. The research, published on January 17, 2024 in Nature Physics, accurately describes neuronal connectivity in a variety of model organisms and could apply to non-biological networks like social interactions as well. “When you’re building simple models to ...

Transforming clinical recording of deep brain activity with a new take on sensor manufacturing

Transforming clinical recording of deep brain activity with a new take on sensor manufacturing
2024-01-17
Sensors built with a new manufacturing approach are capable of recording activity deep within the brain from large populations of individual neurons–with a resolution of as few as one or two neurons–in humans as well as a range of animal models, according to a study published in the Jan. 17, 2024 issue of the journal Nature Communications. The research team is led by the Integrated Electronics and Biointerfaces Laboratory (IEBL) at the University of California San Diego.  The approach is unique in several ways. It relies on ultra-thin, flexible and customizable probes, made of clinical-grade materials, and equipped with sensors that can record extremely localized ...

Role of inherited genetic variants in rare blood cancer uncovered

2024-01-17
Large-scale genetic analysis has helped researchers uncover the interplay between cancer-driving genetic mutations and inherited genetic variants in a rare type of blood cancer. Researchers from the Wellcome Sanger Institute, the University of Cambridge, and collaborators, combined various comprehensive data sets to understand the impact of both cancer-driving spontaneous mutations and inherited genetic variation on the risk of developing myeloproliferative neoplasms (MPN). The study, published today (17 January) in Nature Genetics, describes how inherited genetic variants can influence whether a spontaneous mutation in a particular ...

AI model predicts death, complications for patients undergoing angioplasty, stents

2024-01-17
When a person has one or more blocked arteries, providers may choose to conduct a minimally invasive procedure known as percutaneous coronary intervention, or PCI.  By inflating a balloon and potentially placing a stent, blood can flow more freely from the heart.  Despite carrying less risk than open surgery, stenting and balloon angioplasty can result in complications like bleeding and kidney injury.  Researchers at Michigan Medicine developed an AI-driven algorithm that accurately predicts death and complications after PCI — which could emerge as a tool ...

E-cigarettes help pregnant smokers quit without risks to pregnancy

2024-01-17
A new analysis of trial data on pregnant smokers, led by researchers at Queen Mary University of London, finds that the regular use of nicotine replacement products during pregnancy is not associated with adverse pregnancy events or poor pregnancy outcomes.   The PREP 2 study used data collected from over 1100 pregnant smokers attending 23 hospitals in England and 1 stop-smoking service in Scotland to compare pregnancy outcomes in women who did or did not use nicotine in the form of e-cigarettes (EC) or nicotine patches ...

John Innes Centre researcher honored with prestigious Blavatnik award

John Innes Centre researcher honored with prestigious Blavatnik award
2024-01-17
The pioneering research of Dr Yiliang Ding investigating the structure and function of RNA in living cells has been recognised with a major award.  Yiliang a group leader at the John Innes Centre, is among nine recipients of the 2024 Blavatnik Awards for Young Scientists in the UK, announced today by the Blavatnik Family Foundation and The New York Academy of Sciences.   The awards recognise research that is transforming medicine, technology, and our understanding of the world across three categories: Chemical Sciences, Physical Sciences & Engineering, and ...

Mass-producible miniature quantum memory

Mass-producible miniature quantum memory
2024-01-17
Researchers at the University of Basel have built a quantum memory element based on atoms in a tiny glass cell. In the future, such quantum memories could be mass-produced on a wafer. It is hard to imagine our lives without networks such as the internet or mobile phone networks. In the future, similar networks are planned for quantum technologies that will enable the tap-proof transmission of messages using quantum cryptography and make it possible to connect quantum computers to each other. Like their conventional counterparts, such quantum networks require memory elements in which information can be temporarily stored ...

A new targeted treatment calms the cytokine storm

A new targeted treatment calms the cytokine storm
2024-01-17
Osaka, Japan – Cytokines are chemical messengers that help the body get rid of invading bacteria and viruses, and control inflammation. The body carefully balances cytokines because they help keep the immune system healthy. However, this balance is upset if the immune system overreacts. A serious infection or a severe burn can unleash a cytokine storm in the body. During the storm—also called cytokine release syndrome (CRS)—the body produces too many cytokines, leading to life-threatening inflammation. Interleukin-6 (IL-6) is a key cytokine in the storm because it helps to drive the inflammation that damages ...

Tiny AI-based bio-loggers revealing the interesting bits of a bird’s day

Tiny AI-based bio-loggers revealing the interesting bits of a bird’s day
2024-01-17
Osaka, Japan – Have you ever wondered what wildlife animals do all day? Documentaries offer a glimpse into their lives, but animals under the watchful eye do not do anything interesting. The true essence of their behaviors remains elusive. Now, researchers from Japan have developed a camera that allows us to capture these behaviors. In a study recently published in PNAS Nexus, researchers from Osaka University have created a small sensor-based data logger (called a bio-logger) that automatically detects and records video of infrequent behaviors in wild seabirds without supervision by researchers. Infrequent behaviors, such as diving into the water for food, can ...

SDG-washing found among Canada's top companies

2024-01-17
Canada's biggest companies often speak of their plans to be more sustainable, but a new study found corporations aren't fully backing up those commitments.   A team of University of Waterloo researchers concluded that corporate investing in communities fell despite an increase in companies committing to the United Nation's Sustainable Development Goals (SDGs) over the last decade. Researchers investigated the community investment of Canada's 58 leading private-sector companies as a percentage of their net profit after tax to determine whether introducing SDGs created ...

Enhanced photoelectrochemical water splitting with a donor-acceptor polyimide

Enhanced photoelectrochemical water splitting with a donor-acceptor polyimide
2024-01-17
Polyimide (PI) has emerged as a promising organic photocatalyst owing to its distinct advantages of high visible-light response, facile synthesis, molecularly tunable donor-acceptor structure, and excellent physicochemical stability. However, the synthesis of high-quality PI photoelectrode remains a challenge, and photoelectrochemical (PEC) water splitting for PI has been less studied.   A research group of Huiyan Zhang and Sheng Chu from Southeast University prepared PI films by a ...

Spider venom heart drug a step closer

Spider venom heart drug a step closer
2024-01-17
A spider venom molecule being investigated by a University of Queensland team has met critical benchmarks towards becoming a treatment for heart attack and stroke. Associate Professor Nathan Palpant and Professor Glenn King from UQ’s Institute for Molecular Bioscience have previously shown that the drug candidate Hi1a protects cells from the damage caused by heart attack and stroke. Dr Palpant said a subsequent study has put the drug through a series of preclinical tests designed to mimic real-life treatment scenarios. “These tests are a major step towards helping us understand how Hi1a would work ...

Is soil nitrogen mineralization important in agricultural intensive areas?

Is soil nitrogen mineralization important in agricultural intensive areas?
2024-01-17
Soil nitrogen mineralization (Nmin) is a key process that converts organic N into mineral N that controls soil N availability to plants. However, regional assessments of soil Nmin in cropland and its affecting factors are lacking, especially in relation to variation in elevation. Nitrogen is an essential nutrient for crops but mineral N in soil, the only form that can be absorbed and used by crops, represents only about 1% of total soil N. Although N fertilization is commonly a necessary method for supplying N to crops, N release due to excess N fertilizer in the environment ...

Hepatic TRPC3: an emerging regulator of alcohol-associated liver disease

Hepatic TRPC3: an emerging regulator of alcohol-associated liver disease
2024-01-17
Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.   TRPC (transient receptor potential cation channel protein C) is an evolutionarily conserved non-selective cation channel protein primarily located in the cell membrane with six transmembrane segments. So far four TRPC subfamilies have been identified, categorized into TRPC1, TRPC2, TRPC4/5, and TRPC3/6/7. Among them, TRPC3 is the most well-studied ...

USC Stem Cell study throws our understanding of gene regulation for a loop

USC Stem Cell study throws our understanding of gene regulation for a loop
2024-01-17
The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not random. To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. In a new paper published in Nature Communications, USC Stem Cell scientists from the laboratory ...

A manned submersible found a fault scarp of the 2011 Tohoku-oki megaquake in the Japan Trench

A manned submersible found a fault scarp of the 2011 Tohoku-oki megaquake in the Japan Trench
2024-01-17
Niigata, Japan – On September 4, 2022, a geologist Hayato Ueda in Niigata University boarded a submarine vehicle with a pilot Chris May and had a dive into the Japan Trench within the epicenter area of the 2011 Tohoku-oki megaquake, which caused the devastating tsunami disaster. On the 7,500 m deep trench bottom, they found a 26 m high nearly vertical cliff on the eastern slope of a 60 m high ridge. Previous bathymetric surveys from the sea surface have revealed that the ridge did not exist before, and appeared just after the megaquake ...

Video gamers worldwide may be risking irreversible hearing loss and/or tinnitus

2024-01-17
Video gamers worldwide may be risking irreversible hearing loss and/or tinnitus—persistent ringing/buzzing in the ears—finds a systematic review of the available evidence, published in the open access journal BMJ Public Health.   What evidence there is suggests that the sound levels reported in studies of more than 50,000 people often near, or exceed, permissible safe limits, conclude the researchers.  And given the popularity of these games, greater public health efforts are needed to raise awareness of the potential ...

Enlarged breast tissue in men (gynaecomastia) linked to heightened risk of death

2024-01-17
Men with enlarged breast tissue, not caused by excess weight—a condition formally known as gynaecomastia—may be at heightened risk of an early death before the age of 75, suggests the first study of its kind, published online in the open access journal BMJ Open.   Those with a pre-existing risk factor, such as cancer or circulatory, lung, and gut diseases before diagnosis seem to be most vulnerable, the findings indicate. Enlarged breast tissue in men is usually caused by a hormone imbalance and affects around a third to around two thirds of men, depending on age. It is distinct from what is often dubbed ...
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