Family out-of-pocket expenditure on dental care
2024-03-19
Alexandria, VA, USA – A study aiming to determine if poorer families pay more for dental care as a proportion of their total income than richer families. was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.
The abstract, ...
11th ARDD Meeting Announces initial stellar speaker lineup and XPRIZE Healthspan Team Summit
2024-03-19
According to the United Nations, the proportion of people aged over 65 now outnumber children younger than 5. The enormous growth in the elderly population is posing a socioeconomic challenge to societies worldwide, and necessitates new sweeping interventions for age-associated diseases. This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target the aging process ensuring everyone lives a healthier and longer life. Welcome to the 11th Aging Research and Drug Discovery Meeting.
This year, ARDD is proud to be a partner of XPRIZE ...
Cell therapy approach harnesses the immune system in a different way to stop cancer
2024-03-19
NOTE TO EDITORS: High-resolution b-roll, soundbites and images are available for download at https://bit.ly/3PfnX5Y
COLUMBUS, Ohio – A new cancer treatment that uses a person’s own immune cells has been approved by the U.S. Food and Drug Administration (FDA) for treating the most dangerous type of skin cancer. Now this form of cellular therapy (tumor-infiltrating lymphocyte – or TIL therapy) is showing promise in advanced lung cancers through clinical trials underway at The Ohio State University Comprehensive Cancer ...
Artificial intelligence algorithms for understanding the determinants of oral health
2024-03-19
Alexandria, VA, USA – A study aiming to use AI and predictive models to forecast the likelihood of permanent tooth loss, as an indicator of overall oral health, based on various behavioral and lifestyle factors was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.
The abstract, “Artificial Intelligence Algorithms for Understanding the Determinants of Oral Health” was presented during ...
Predicting oral cancer-related mortality among adults using machine learning approach
2024-03-19
Alexandria, VA, USA – A study aiming to predict oral cancer-related mortality among adults in the United States and identify the predictors of oral cancer-related mortality using the Machine Learning Approach. was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.
The abstract, “Predicting Oral Cancer-Related Mortality among Adults Using Machine Learning Approach” was presented ...
Harnessing biomaterial-based FTY720 immunotherapy to accelerate oral wound healing
2024-03-19
Alexandria, VA, USA – A study aiming to deliver Fingolimod (FTY720) loaded polymer scaffolds to enhance oral wound healing by modulating pro-regenerative immune cell migration associated with improved vascularization and tissue remodeling was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.
The abstract, “Harnessing Biomaterial-Based ...
Oral health behaviors associated with mental health disorders
2024-03-19
Alexandria, VA, USA – A study aiming to examine oral hygiene self-care behavior among patients with self-reported mental health disorders was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.
The abstract, “Oral Health Behaviors Associated with Mental Health Disorders” was presented during the ...
Researchers develop deep learning model to predict breast cancer
2024-03-19
OAK BROOK, Ill. – Researchers have developed a new, interpretable artificial intelligence (AI) model to predict 5-year breast cancer risk from mammograms, according to a new study published today in Radiology, a journal of the Radiological Society of North America (RSNA).
One in 8 women, or approximately 13% of the female population in the U.S., will develop invasive breast cancer in their lifetime and 1 in 39 women (3%) will die from the disease, according to the American Cancer Society. Breast ...
Social activities can prevent cognitive decline in care facility residents
2024-03-19
Social activities such as interactions with others and participation in organised events can prevent cognitive decline in long-term care facility. Research from Amsterdam UMC, carried out among 3600 patients in 42 Dutch and Belgian care homes, shows that participation in social activities offers a protective effect for those with no, or little, cognitive impairment. These results are published today in the Journal of Alzheimer's Disease.
"Cognitive decline in long-term care residents is relatively common, a Canadian study showed that almost a quarter of residents cognitively declined after a year of residency," ...
BU study finds coping is related to longevity in older men
2024-03-19
(Boston)—Coping is defined as cognitive and behavioral efforts to manage stressors that people believe exceed their ability and resources to respond to effectively. While previous research has linked stressor characteristics, such as the type of event and its duration, and how stressed people feel in response to them, to higher mortality risk, far fewer studies have considered the long-term health consequences of how we manage stressors (coping) in large-scale studies.
In a new study from ...
MRI and lumbar puncture not necessarily required to manage CAR T-cell therapy complications
2024-03-19
(WASHINGTON, March 19, 2024) – Magnetic resonance imaging (MRI) and lumbar puncture (LP) may not always be necessary for diagnosing and managing a serious neurological complication associated with CAR T-cell therapy, according to a new Blood Advances study. Findings further validated the use of the electroencephalogram (EEG) – a noninvasive test measuring electrical activity in the brain – in managing this neurotoxicity.
“When treating patients for CAR T-cell associated toxicities, we typically follow pretty ...
Empty “backpacks” activate the immune system against cancer
2024-03-19
Most of the white blood cells in your body are a type of cell called neutrophils. Despite their high numbers, they are less well understood than other immune cells, in part because they have very short lifespans: an average neutrophil lives for only eight hours. However, recent work has shown that neutrophils are very flexible cells, capable of dialing inflammation up or down, especially in the context of cancer. This makes them attractive targets for immunotherapy, which aims to tweak the immune system to more potently attack disease. But neutrophil-based ...
Dehydration is rampant among Florida farm workers, new study shows
2024-03-19
Nearly all farm workers who participated in a recent study in Florida were dehydrated at the end of their shifts, and more than half were still dehydrated the following morning.
The study, a partnership between the University of Illinois Chicago and the Farmworker Association of Florida, used urine samples collected first thing in the morning, at lunch and at the end of a shift to assess the risk of dehydration over five days in May 2021 and May 2022 at a vegetable farm in southern Florida. A total of 111 workers, most of them men from Mexico and Guatemala, participated in the study, which is published in the journal ...
Climate change graphics are important, so make them simple
2024-03-19
When the “hockey stick” graph, which illustrated a steep increase in global temperatures, was published in 1998, it reshaped the world’s understanding of climate change. A quarter-century later, with climate change now wreaking havoc around the world, graphics depicting global warming are more important than ever to inform policymaking.
However, a recent USC-led study reveals that some graphics developed for reports by the Intergovernmental Panel on Climate Change (IPCC) are too complex, even for the intended audiences of policymakers and practitioners.
Researchers recommend limiting each graphic, which the IPCC refers to as “figures,” ...
Rising rates of head and facial injuries from exercise and weightlifting
2024-03-19
Waltham — March 18, 2024 — Numbers of craniofacial injuries related to exercise and weightlifting have increased sharply over the past decade, reports a study in The Journal of Craniofacial Surgery. The journal is published in the Lippincott portfolio by Wolters Kluwer.
"Incidence of craniofacial injury significantly increased between 2013 and 2022, illuminating the need for better education and risk mitigation strategies," according to the new research by Rohan Mangal, MSc, and colleagues of University of Miami. Rates of exercise-related head and facial injuries appear higher for men than women, and ...
A breakthrough in solid-state electrolytes for all-solid-state batteries: Twice the quality with streamlined processes
2024-03-19
Korea Electrotechnology Research Institute (KERI) has reached a significant milestone with the publication of a groundbreaking study in a globally esteemed journal, marking a crucial stride toward the commercialization of all-solid-state batteries, free from the inherent risks of explosion and fire.
Dr. Park Jun-woo of the KERI Next-Generation Battery Research Center and Sung Junghwan (student researcher at the UST KERI Campus) have successfully engineered a revolutionary technology. This technology, focused on the "size-controlled ...
Circulating tumor DNA levels predict treatment outcomes for patients with gastroesophageal cancer treated with a novel immunotherapy combination
2024-03-19
Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.
The study tracked minimal residual disease (the amount of cancer left following treatment) by analyzing circulating tumor DNA (ctDNA), showing how these ...
Association between miR-492 rs2289030 G>C and susceptibility to neuroblastoma in Chinese children from Jiangsu province
2024-03-19
Neuroblastoma is a heterogeneous solid tumor that originates extracranially from neuroblasts. Previous research has demonstrated that miR-492 polymorphisms can contribute to cancer susceptibility. However, their specific involvement in susceptibility to neuroblastoma has yet to be fully clarified.
Background and objectives
Neuroblastoma is a heterogeneous solid tumor that originates extracranially from neuroblasts. Previous research has demonstrated that miR-492 polymorphisms can contribute to cancer susceptibility. However, their specific involvement in susceptibility to neuroblastoma has yet to be fully clarified.
In this study, we focused on miRNA-492, which has been reported to ...
Choosing over the counter drugs for COVID 19? It’s complicated
2024-03-19
COVID-19 illness may include symptoms such as a sore throat, fever, cough and fatigue. In January, the United States Centers for Disease Control and Prevention (CDC) issued its most recent guidelines for the use of over the counter (OTC) drugs for COVID-19. Specifically, its guidelines state that most people with COVID-19 have mild illness and can recover at home while treating symptoms with OTC medicines such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil).
Researchers from Florida Atlantic University’s Schmidt College ...
Binghamton University’s Speech and Language Pathology program receives accreditation candidacy
2024-03-19
BINGHAMTON, N.Y. -- The new Master of Science in Speech and Language Pathology (MS-SLP) program at Binghamton University’s Decker College of Nursing and Health Sciences has achieved a significant milestone toward accreditation by the Council on Academic Accreditation in Audiology and Speech-Language Pathology (CAA). The council recently awarded the program accreditation candidacy for five years, beginning Feb. 1, 2024, and running through Jan. 31, 2029.
The decision was based on a thorough review of all candidacy materials for the program, including the application, site visit report and the program’s ...
Characterizing salps as predators of marine microbes
2024-03-19
A huge fraction of global flows of carbon and other nutrients passes through marine microbes, little is known about their causes of death—information that in many cases determines where those nutrients will go. Recent work on microbial death via viral lysis and protistan predation is helping close the gap, but there remains a missing source of microbial mortality. Anne Thompson and colleagues explore the role played by salps, pelagic tunicates that feed by pumping seawater through mucous mesh nets, filtering out and capturing particles such as preferred microbes. Salps send ...
Four PPPL researchers featured in the Physics of Plasmas Early Career Collection
2024-03-19
The U.S. Department of Energy’s Princeton Plasma Physics Laboratory (PPPL) made a strong showing in this year’s Early Career Collection from the scientific journal Physics of Plasmas. The collection represents the top papers from all areas of plasma physics research authored by people who defended their dissertations less than five years before the journal article was submitted.
“The first authors of the pieces in the 2023 Early Career Collection have made a notable contribution to the field of plasma and show significant promise. I look forward to ...
Does AI help or hurt human radiologists’ performance? It depends on the doctor
2024-03-19
One of the most touted promises of medical artificial intelligence tools is their ability to augment human clinicians’ performance by helping them interpret images such as X-rays and CT scans with greater precision to make more accurate diagnoses.
But the benefits of using AI tools on image interpretation appear to vary from clinician to clinician, according to new research led by investigators at Harvard Medical School, working with colleagues at MIT and Stanford.
The study findings suggest that individual clinician differences shape the interaction between human ...
Scientists identify Achilles heel of lung cancer protein
2024-03-19
Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
The study was led by the Science and Technology Facilities Council (STFC) Central Laser Facility (CLF) and used advanced laser imaging techniques to identify structural details of a mutated protein which help it to evade drugs that target it.
It is published (19/03/2024) in the journal, Nature Communications and lays the groundwork for future research into ...
Insulin affects the recycling of cellular power plants
2024-03-19
The hormone insulin controls many cellular processes and adapts them to the body’s current energy supply. One of the insulin-regulated processes is the quality control of cellular power plants in neurons, Angelika Harbauer and her team at the Max Planck Institute for Biological Intelligence discovered. When sufficient energy is available in the body, insulin facilitates the elimination of defective mitochondria. When energy is scarce or when the insulin signal is interrupted, mitochondrial recycling is reduced and cells continue to use their old power plants, even potentially damaged ones. The continued operation of faulty mitochondria could affect ageing ...
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