Simulated High-altitude exposure for 24-hours is well tolerated by adolescents and adults with single-ventricle physiology after Fontan-palliation
The researchers conducted a study over four days, including overnight stays, with 18 subjects at :envihab, the DLR medical research centre in Cologne. At a simulated altitude of 2500 meters above sea level, the influence of hypoxia (oxygen deficiency) on various hemodynamic and metabolic parameters was investigated. The central venous pressure via a catheter and the blood flow in the lungs using real-time magnetic resonance imaging were evaluated. The results showed that neither the pulmonarypressure nor the blood flow changed significantly. All patients able to tolerate a longer stay at altitude of 24 to 30 hours without complications. Oxygenation ...
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