A research team at The Hastings Center has been approved for $1.5 million in funding by the Patient-Centered Outcomes Research Institute (PCORI) to study organizational trustworthiness as it relates to community-engaged research. Led by Virginia A. Brown, PhD, a research scholar at The Hastings Center, the study will be the first to investigate the role of organizational trustworthiness in shaping research engagement processes and outcomes. Measures to assess organizational trustworthiness as it relates to research ...

Philadelphia, August 13, 2024 – Research into reducing greenhouse gas emissions from livestock has increased exponentially as the dairy and agriculture sectors work together toward shared sustainability and efficiency goals. While this progress has been made in all areas of dairy science research, from genetics to animal health and welfare, dairy nutrition has emerged as a particularly impactful area for emission reduction. In a new invited review in the Journal of Dairy Science, a preeminent voice in sustainability and dairy nutrition synthesizes ...

By modifying a plant intracellular immune receptor (NLR), researchers have developed a potential new strategy for resistance to rice blast disease, one of the most important diseases threatening global food security. The collaborative team from the UK and Japan have recently published their research in PNAS. This could have implications for future approaches to crop protection and ultimately global food supply stability.  The research was led from the Department of Biochemistry and Metabolism at the John Innes Centre, with partners at The Sainsbury Laboratory, University of East Anglia, and the Division of Genomics and Breeding, Iwate Biotechnology Research Center, Japan. For a ...

With a new polymer that only attracts certain substances from solutions when electrically activated, researchers have taken a major step towards sustainable chemical separation. A team based at the University of Illinois Urbana-Champaign has reported the first demonstration of selective electrochemical separation driven by halogen bonding in the journal JACS Au. This was achieved by engineering a polymer that modulates the charge density on a halogen atom when electricity is applied. The polymer then attracts only certain targets – such as halides, oxyanions, and even organic molecules – from organic solutions, ...

NEW YORK, August 13, 2024 — A recently published study in Ecological Applications details how trees in New York City and Boston are more negatively impacted by heat waves and drought than trees of the same species in nearby rural forests. The finding, made by researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC), highlights the challenges urban trees face in the context of climate change and underscores the importance of tailored urban forestry management as ...

JUPITER, Fla. — Children born with a damaged gene needed for healthy brain development, SYNGAP1, experience seizures, sensory processing disorders, difficulty speaking, intellectual disability, and autism-like behaviors. It’s a condition without any treatments, one that’s hard both on parents and children, said Gavin Rumbaugh, Ph.D., a neuroscientist at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology. Rumbaugh and a team of scientists from the institute have been awarded a five-year grant from the National Institute of Mental Health worth $7.7 million to work toward a treatment. Their goal is to ...

Depression is common among people with likely incurable cancer – understandably so. But studies have shown that it can be treated, and if the goal is for individuals to be able to engage as much as possible with family, friends, hobbies or whatever gives them joy and purpose in whatever amount of time they have, then treating depression becomes imperative.   That’s not so easy, though, as patients may face a shortage of mental health workers, difficulties with transportation and continuing stigma around mental health issues.   Evan Graboyes, M.D., a head and neck surgical oncologist and director of Survivorship ...

New research from Memorial Sloan Kettering Cancer Center (MSK) found patients with non-small cell lung cancer brain metastases may benefit from up-front stereotactic radiosurgery; identified a connection between antibiotic use and autoimmune diseases; and uncovered a previously unknown structural role for messenger RNAs in the cytoplasm of cells. Patients with non-small cell lung cancer brain metastases may benefit from upfront stereotactic radiosurgery For patients with non-small cell lung cancer that has spread to the brain, targeted therapies called ...

A study involving 22 Parkinson’s disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality. When the patients took the drug, the number of times they woke up during the night fell 25% and the amount of time they remained awake fell 30% on average.  The investigation was conducted with FAPESP’s support by researchers at São Paulo State University (UNESP) in Brazil, and the University of Grenoble Alpes (UGA) in France. An article reporting the results is published in ...

Tailoring light with Nanomaterials Metamaterials, engineered at the nanoscale, exhibit unique properties not found in naturally occurring materials. These properties arise from their nanoscale building blocks, which, until now, have been challenging to observe directly due to their size being smaller than the wavelength of light. The team's research overcomes this limitation by employing a new microscopy technique that can simultaneously reveal both the nano and macro structures of these materials. A New Window into the Nano World The key finding of this research is a methodological breakthrough that enables the visualization of structures previously too small to be seen ...

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptor with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ...

Our nation’s security depends on the effective detection of nuclear materials at our borders and beyond. To address this challenge, Rensselaer Polytechnic Institute (RPI) physicist Moussa N’Gom, Ph.D., is leading research aimed at developing a quantum sensing probe to detect and characterize special nuclear materials precisely and without contact. Special nuclear materials are only mildly radioactive but can be used in nuclear explosives. The research is being conducted through RPI’s participation in the Consortium ...

The atmosphere within a group can influence the outcome of strategic decision-making, according to a new study co-authored by Bayes Business School (formerly Cass).  Paula Jarzabkowski, Professor of Strategic Management at Bayes, along with researchers from University of Queensland, Macquarie University and Leuphana University of Lüneburg, found that different atmospheres led to people speaking and interacting in different ways that changed how they made sense of the strategy.   For instance, when the atmosphere was pensive, people were cautious about the way to proceed, whereas, when it was curious they felt ...

The Institute of Intelligent Medical Research (IIMR) of BGI Genomics, in collaboration with Sweden’s Uppsala University, has published the largest multi-omics study of colorectal cancer (CRC) to date. The study aimed to understand the functional and prognostic impact of cancer-causing somatic mutations, revealing new genetic alterations and developing a new molecular classifier of tumor variants. This research was published in the journal Nature on August 7th, 2024. Unveiling New Genetic Landscapes The researchers analyzed the whole genomes and transcriptomes ...

WASHINGTON, Aug. 13, 2024 – Key to winning a cricket match is tricking the other team’s batters – no small feat as bowlers bowl cricket balls nearly 100 miles per hour. In recent years, a bowling technique that has become popular involves keeping the arm almost entirely horizontal during delivery, notably used by Sri Lankan stars Lasith Malinga and Matheesha Pathirana. The aerodynamics of such deliveries have perplexed sports physicists. In Physics of Fluids, by AIP Publishing, researchers have started to unravel the mysteries of how ...

WASHINGTON, Aug. 13, 2024 – Mars has a notoriously inhospitable environment, with temperatures that fluctuate dramatically over the course of a Martian day and average minus 80 degrees Fahrenheit. Its surface is mostly covered in red dust, with terrain typified by craters, canyons, and volcanoes. And its atmosphere is extremely thin, comprising only about 1% of the density of Earth’s. Needless to say, measuring wind speeds on the red planet is challenging. Martian landers have been able capture measurements — some gauging the cooling rate of heated materials ...

About The Study: The findings of this cohort study of patients with comorbid posttraumatic stress disorder (PTSD) and type 2 diabetes suggest that PTSD is a modifiable risk factor associated with a modest reduction in microvascular complications. Further research is needed to determine whether findings are similar in non-Veterans Health Administration health care settings.  Corresponding Author: To contact the corresponding author, Jeffrey F. Scherrer, PhD, email jeffrey.scherrer@health.slu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.27569) Editor’s ...

About The Study: In this 1-year prospective cohort study of children with smartwatches, continuous outdoor exposure with at least 15 minutes accompanied with no less than 2,000 lux sunlight intensity was associated with less myopic shift. These findings suggest that future outdoor interventions should focus not only on the overall time outdoors but also on the effective outdoor exposure patterns, as a means to effectively prevent myopia (nearsightedness) in children.  Corresponding Authors: To ...

Ann & Robert H. Lurie Children’s Hospital of Chicago, in partnership with University of Utah Health, has been approved for $12 million in research funding by the Patient-Centered Outcomes Research Institute (PCORI) for a study that will compare two ways to use antibiotics in young children with mild pneumonia, one of the leading reasons children seek acute care, who are well enough to be cared for at home. The first approach is to prescribe and give antibiotics immediately, which is the current standard of care. The second way is to prescribe an antibiotic but not give it unless the child’s symptoms worsen or ...

PCORI announces $165 million in funding for new health research   Approved awards support patient-centered comparative clinical effectiveness research (CER) on telehealth interventions, heart care and various health concerns Aug. 13, 2024 WASHINGTON, D.C. – The Patient-Centered Outcomes Research Institute (PCORI) today announced the approval of funding awards totaling more than $165 million for new patient-centered comparative clinical effectiveness research (CER), as well as research to improve methods and strengthen the science of engagement in patient-centered CER. Among the 10 CER studies awarded, three will evaluate the effectiveness of telehealth interventions ...

(COLUMBUS, Ohio) – Researchers from the Center for Injury Research and Policy and Central Ohio Poison Center at Nationwide Children’s Hospital have found more than an estimated 8,000 visits to U.S. emergency departments (EDs) associated with water beads from 2007 through 2022, and the number of these visits increased rapidly by more than 130% from 2021 to 2022. In a study published in American Journal of Emergency Medicine, researchers analyzed 16 years of data and call for a more comprehensive regulatory approach to prevent water bead-associated injuries. The increase in ...

A Macquarie University team proposes using genetically engineered black soldier flies (Hermetia illucens) to address worldwide pollution challenges and produce valuable raw materials for industry, including the USD $500 billion global animal feed market.  In a new paper published on 24 July in the journal Communications Biology, scientists at Macquarie University outline a future where engineered flies could transform waste management and sustainable biomanufacturing, addressing multiple United Nations Sustainable Development Goals (SDGs).  Synthetic biologist Dr Kate Tepper is lead author of the paper and a Postdoctoral Research Fellow at Applied BioSciences, Macquarie University. “One ...

OAK BROOK, Ill. – A new study of more than 10,000 non-smoking adults found that solid lung nodules were present in a considerable portion of study participants. Non-smokers are traditionally thought to be at low risk for lung nodules and lung cancer. The results of the study were published today in Radiology, a journal of the Radiological Society of North America (RSNA). Incidental lung nodules are common findings on chest CT and in high-risk groups are more likely to be a sign of early-stage lung cancer. Because most previous research on the prevalence and size of lung nodules has typically been ...

(COLUMBUS, Ohio) – As the nation’s youth mental health crisis continues, providers continue to find ways to help address gaps in care. Patients who receive care for suicidal thoughts and behaviors need extra support as they transition after they are discharged from inpatient care or the emergency department. Caring Contacts are validating messages sent to patients via text messages, postcards or letters to offer patients ongoing care and support without placing any demands (such as reminders to attend their next appointment). At Nationwide ...

WASHINGTON, Aug. 13, 2024 — The American Chemical Society (ACS) is hosting ACS Fall 2024, its virtual and in-person meeting, with the theme “Elevating Chemistry.” It will take place in Denver on Aug. 18-22. About 10,000 presentations will feature cutting-edge developments on a range of scientific topics at ACS Fall 2024. Embargoed press releases and videos are available to members of the media on the EurekAlert! website. Reporters can also email newsroom@acs.org to request access to the embargoed content. View the ACS Fall 2024 schedule for a full list of in-person, hybrid ...