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Damon Runyon Cancer Research Foundation awards $3.9 million to exceptional early-career scientists

2023-08-16
The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators. This prestigious Fellowship encourages the nation’s most promising young scientists to pursue careers in cancer research by providing them with independent funding to investigate cancer causes, mechanisms, therapies, and prevention. In July 2023, the Board of Directors announced a 15% ...

Assessing controls on ocean productivity – from space

2023-08-16
Phytoplankton determine how much life the ocean is able to support and play a role in controlling atmospheric carbon dioxide concentrations, thereby regulating our climate. These tiny marine plants depend on sunlight as well as nutrients to thrive – including elements such as iron or nitrogen that can be brought to the ocean surface by currents and upwelling. To understand phytoplankton nutrient limitations in the ocean, scientists typically conduct experiments during research expeditions at sea. However, this approach documents only a tiny fraction of the ocean at a certain point in time. Therefore, an international team of researchers tested if a signal detected by satellites in ...

Medications for chronic diseases affect the body’s ability to regulate body temperature, keep cool

2023-08-16
Medications to treat various chronic diseases may hinder the body’s ability to lose heat and regulate its core temperature to optimal levels. The loss of effective thermoregulation has implications for elderly people receiving treatment for illnesses like cancer, cardiovascular, Parkinson’s disease/dementia and diabetes, particularly during hot weather, according to a review by a team of scientists from various institutions in Singapore. The group, led by Associate Professor Jason Lee from the Human Potential Translational Research Programme at the Yong Loo Lin School of ...

New leaf-tailed gecko from Madagascar is a master of disguise

New leaf-tailed gecko from Madagascar is a master of disguise
2023-08-16
Leaf-tailed geckos are masters of camouflage. Some species have skin flaps around the whole body and head, as well as flattened tails. During the day, they rest head-down on tree trunks with these skin flaps spread out, and blend seamlessly into their surroundings, making them nearly impossible to spot. At night, they awaken to prowl the fine branches of the understory looking for invertebrate prey. “When we first discovered this species in 2000, we already suspected it might be new to science,” says Dr Frank Glaw, curator of herpetology at the Bavarian State Collection of Zoology, lead author on the study. “But ...

MD Anderson research highlights for August 16, 2023

2023-08-16
HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel single-cell sequencing technology that allows for rapid analyses of archived and frozen cells, greater understanding of the ...

Switching ‘spin’ on and off (and up and down) in quantum materials at room temperature

Switching ‘spin’ on and off (and up and down) in quantum materials at room temperature
2023-08-16
Researchers have found a way to control the interaction of light and quantum ‘spin’ in organic semiconductors, that works even at room temperature. Spin is the term for the intrinsic angular momentum of electrons, which is referred to as up or down. Using the up/down spin states of electrons instead of the 0 and 1 in conventional computer logic could transform the way in which computers process information. And sensors based on quantum principles could vastly improve our abilities to measure and study the world around us. An international team of researchers, led by the University of ...

Research finds that molecules in vegetables can help to ease lung infection

Research finds that molecules in vegetables can help to ease lung infection
2023-08-16
Francis Crick Institute press release Under strict embargo: 16:00hrs BST 16 August 2023 Peer reviewed Experimental study Animals Research finds that molecules in vegetables can help to ease lung infection Researchers at the Francis Crick Institute have found that molecules in vegetables like broccoli or cauliflower help to maintain a healthy barrier in the lung and ease infection. The AHR – aryl hydrocarbon receptor – is a protein found at barrier sites like the gut and the lung. Natural molecules in cruciferous vegetables – for example, kale, cauliflower, broccoli, or cabbage – are dietary ...

Collecting clean water from fog

2023-08-16
In countries such as Peru, Bolivia and Chile, it’s not uncommon for people who live in foggy areas to hang up nets to catch droplets of water. The same is true of Morocco and Oman. These droplets then trickle down the mesh and are collected to provide water for drinking, cooking and washing. As much as several hundred litres of water can be harvested daily using a fog net only a few square metres in area. For regions with little rain or spring water, but where fog is a common occurrence, this can be a blessing. One crucial drawback with this method, however, ...

Mental illness following physical assault among children

2023-08-16
About The Study: Children who experienced assault had, on average, a 2 times higher risk of receiving a mental illness diagnosis and were more likely than children who had not experienced assault to present to acute care for mental illness. Early intervention to support mental health of assaulted children is warranted, particularly in the first year following assault.  Authors: Natasha Ruth Saunders, M.D., M.Sc., of the Hospital for Sick Children in Toronto, is the corresponding author.   To ...

Prevalence, factors associated with vaping CBD among adolescents

2023-08-16
About The Study: In this study of 28,000 middle and high school students, the prevalence of vaping cannabidiol (CBD) was high, particularly among e-cigarette users and Hispanic and sexual minority populations. The findings suggest that evidence-based educational campaigns, interventions, and public policy changes are needed to reduce the harmful health outcomes possible with vaping CBD among developing youths.  Authors: Hongying Daisy Dai, Ph.D., of the University of Nebraska Medical Center in Omaha, is the corresponding author.   To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2023.29167) Editor’s ...

Patterns in cancer incidence among people younger than age 50

2023-08-16
About The Study: The incidence rates in the U.S. of early-onset cancer (younger than age 50) increased from 2010 to 2019 in this study of 562,000 patients. Although breast cancer had the highest number of incident cases, gastrointestinal cancers had the fastest-growing incidence rates among all early-onset cancers. These data may be useful for the development of surveillance strategies and funding priorities.  Authors: Daniel Q. Huang, M.B.B.S., M.M.E.D., and Cheng Han Ng, M.B.B.S., of the National University of Singapore, are the corresponding authors.   To access the embargoed study: ...

Scientists find way to wipe a cell’s memory to better reprogram it as a stem cell

Scientists find way to wipe a cell’s memory to better reprogram it as a stem cell
2023-08-16
In a groundbreaking study published today  in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of Medical Research and The University of Western Australia and Professor Jose M Polo from Monash University and the University of Adelaide, the team developed a new method to reprogram human cells to better mimic embryonic stem cells, with significant implications for biomedical and therapeutic uses. In a revolutionary advance in the mid-2000s, it was ...

Paternal depression and risk of depression among offspring

2023-08-16
About The Study: Paternal depression was associated with subsequent offspring depression in this systematic review and meta-analysis including 7.1 million father-child dyads from 16 observational studies. This finding shows the intergenerational transmission of mental health problems and suggests that mental health interventions benefit not only the patient but also the family as a whole, including both parents.  Authors: Berihun Dachew, Ph.D., of Curtin University in Perth, Australia, is the corresponding author.   To ...

Normal graft function after pig-to-human kidney xenotransplant

2023-08-16
About The Study: The findings from this case series show that pig-to-human xenotransplant provided life-sustaining kidney function in a deceased human with chronic kidney disease. Future research in living human recipients is necessary to determine long-term xenograft kidney function and whether xenografts could serve as a bridge or destination therapy for end-stage kidney disease. Authors: Jayme E. Locke, M.D., M.P.H., of the University of Alabama at Birmingham Heersink School of Medicine, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamasurg.2023.2774) Editor’s ...

Blood factor can turn back time in the aging brain

2023-08-16
Blood Factor Can Turn Back Time in the Aging Brain  Platelets are behind the cognitive benefits of young blood, exercise and the longevity hormone klotho  In a remarkable convergence, scientists have discovered that the same blood factor is responsible for the cognitive enhancement that results from young blood transfusion, the longevity hormone klotho, and exercise.     In a trio of papers appearing in Nature, Nature Aging and Nature Communications on August 16, 2023, two UCSF teams and a team from the University of Queensland (Australia), identify platelet ...

How cold temperatures trigger the brain to boost appetite

How cold temperatures trigger the brain to boost appetite
2023-08-16
LA JOLLA, CA—Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures. Mammals automatically burn more energy to maintain normal body temperature when exposed to cold. This cold-activated increase in energy expenditure triggers an increase in appetite and feeding, although the specific mechanism controlling this had been unknown. In the new study, reported on August 16, 2023, in Nature, the researchers identified a cluster of neurons that work as a “switch” for this cold-related, food-seeking behavior in mice. The discovery could lead to potential ...

Microplastic pollution: Plants could be the answer

Microplastic pollution: Plants could be the answer
2023-08-16
Could plants be the answer to the looming threat of microplastic pollution? Scientists at UBC’s BioProducts Institute found that if you add tannins—natural plant compounds that make your mouth pucker if you bite into an unripe fruit—to a layer of wood dust, you can create a filter that traps virtually all microplastic particles present in water. While the experiment remains a lab set-up at this stage, the team is convinced that the solution can be scaled up easily and inexpensively once they find the right industry partner. Microplastics ...

Directly involved war veterans exhibit nearly twice the PTSD symptoms years after 2014 Israel-Gaza conflict, affecting parents' well-being

2023-08-16
Hebrew University researchers, Shahaf Leshem, Eldad Keha, and Prof. Eyal Kalanthroff, have unveiled significant findings regarding the lasting psychological impacts stemming from the 2014 Israel-Gaza military conflict. The study sheds light on the deep repercussions of trauma for both war veterans and their parents. Notably, veterans directly involved in the conflict exhibited nearly twice the level of PTSD symptoms compared to indirectly active veterans, a difference persisting even five years after the conflict. Remarkably, ...

Study finds improved survival for incurable brain tumor, providing ‘a crack in the armor’

Study finds improved survival for incurable brain tumor, providing ‘a crack in the armor’
2023-08-16
Michigan — For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound, called ONC201, nearly doubled survival for patients with diffuse midline glioma (DMG) or diffuse intrinsic pontine glioma (DIPG), compared to previous patients.   The findings are reported by an international team of researcher led by the University of Michigan Health Rogel Cancer Center and the Chad Carr Pediatric Brain Tumor Center.   In addition to reporting on the results of two early stage clinical ...

Pig kidney xenotransplantation performing optimally after 32 days in human body

Pig kidney xenotransplantation performing optimally after 32 days in human body
2023-08-16
NEW YORK, NY, AUGUST 16, 2023 — Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support. This represents the longest period that a gene-edited pig kidney has functioned in a human, and the latest step toward the advent of an alternate, sustainable supply of organs for transplant. Multimedia Materials Available Multimedia materials, including photos and a B-roll package, are available for download. About the Procedure The procedure, performed on July 14, 2023, and led by Robert Montgomery, ...

ASBMB names 2024 award winners

2023-08-16
The American Society for Biochemistry and Molecular Biology announced today the winners of its annual awards. Colleagues and other leaders in the field nominated the winners for making significant contributions to biochemistry and molecular biology and the training of emerging scientists. The recipients will give talks about their work at the society’s 2024 annual meeting, Discover BMB, slated for March 23–26 in San Antonio. In addition to cash prizes ranging from $2,000 to $35,000, each ASBMB award consists of a plaque and transportation ...

New and updated resources published to help guide oncology care in the Middle East and North Africa (MENA)

2023-08-16
PLYMOUTH MEETING, PA [August 16, 2023] — The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—today announced that a library of resources for improving cancer care in the Middle East and North Africa (MENA) has been updated and expanded in collaboration with regional experts. The United States-based non-profit has worked with the King Abdulaziz Medical City in Riyadh, Saudi Arabia, since 2015 to standardize cancer treatment based on the latest evidence and expert-consensus, as part of the MENA-NCCN Regional Coordinating Center. Their efforts have led to the ...

Gray wolf recovery is a success—is that a problem?

2023-08-16
Over the past 30 years, efforts to recover gray wolf populations in the United States have been broadly successful, with many regions now sporting robust populations of the charismatic carnivore. Writing in BioScience, wolf experts David E. Ausband and L. David Mech describe the conservation landscape and also the obstacles that wolves face as their populations expand into their historical ranges.                 "Remarkable wolf conservation success yields remarkable challenges," ...

Common wristbands ‘hotbed’ for harmful bacteria including E. coli, staphylococcus

Common wristbands ‘hotbed’ for harmful bacteria including E. coli, staphylococcus
2023-08-16
The COVID-19 pandemic took disinfecting to new heights. Now, a new study examining a commonly used item might convince you not to let your guard down just yet. Researchers from Florida Atlantic University’s Charles E. Schmidt College of Science tested wristbands of various textures to determine their risk for harboring potentially harmful pathogenic bacteria. Despite being worn daily, routine cleaning of wristbands is generally overlooked or simply ignored. For the study, researchers tested plastic, rubber, cloth, leather ...

What is the next step in preventative therapies for treating liver cancer?

What is the next step in preventative therapies for treating liver cancer?
2023-08-16
Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries. Despite significant progress in diagnosis and treatments, HCC, often diagnosed at late stages, remains a life-threatening disease with an increasing incidence. Therefore, a better understanding of the underlying mechanisms triggering the early steps of tumorigenesis represents a great interest to predict and propose more effective therapeutic ...
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