In preclinical models, the subcutaneously implanted device continuously monitored vital signs and delivered naloxone automatically and rapidly when it detected opioid overdose The opioid epidemic continues to have devastating effects in the United States, exacerbated by the increasing presence of fentanyl in illicit opioids. Naloxone is an effective antidote, but it usually requires rapid administration from a bystander. Now, researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare ...

As the Paris Olympics captured the world’s attention this month, it proved apparent that winning medals often hinged on the success of teamwork. While such an approach clearly works in sports, new research suggests teamwork is not always the desired method … especially for young scientists trying to find an academic job. “We found that if your team size in your discipline is large, your prospects for an academic career go down,” said Donna Ginther, the Roy A. Roberts Distinguished Professor of Economics at the University of Kansas. Her paper titled “The rise of teamwork and career prospects in academic science” ...

An international research team led by the Centre for Microbiology and Environmental Systems Science (CeMESS) at the University of Vienna has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source. This unique ability opens new avenues for targeted cultivation of these enigmatic microbes and could also provide a key to reducing agricultural nitrous oxide emissions. The research findings were recently published as an article in the prestigious journal Nature. Nitrification, the conversion of ammonia via nitrite to nitrate, is ...

High-end bicycles used for high-profile road races such as the Tour de France are vulnerable to cybersecurity attacks targeting the bike’s wireless gear shifting system.  In recent years, bicycle manufacturers have adopted wireless gear-shifting technology, which gives riders better control over changing gears. The technology is not vulnerable to the physical issues that plague mechanical systems. However, the way the wireless systems were built created critical cybersecurity vulnerabilities, which a team of computer scientists from the University of California ...

A major international study has explained how bread wheat helped to transform the ancient world on its path to becoming the iconic crop that today sustains a global population of eight billion.  “Our findings shed new light on an iconic event in our civilisation that created a new kind of agriculture and allowed humans to settle down and form societies,” said Professor Brande Wulff, a wheat researcher at KAUST (King Abdullah University of Science and Technology) and one of the lead ...

A new technique developed at Lawrence Berkeley National Laboratory (Berkeley Lab) will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species. The approach, called barcoded overexpression bacterial shotgun library sequencing, or Boba-seq, is described in a paper published August 5 in Nature Communications.   “There is so much genetic dark matter – ...

Annapolis, MD; August 14, 2024—A common variety of consumer insecticide sprays is mostly ineffective and of "little to no value" in eliminating cockroach infestations, a new study shows. Residual insecticides are designed to be sprayed on surfaces where cockroaches are likely to appear, exposing them to the toxic ingredient when they move across the surface later. But laboratory testing by researchers at the University of Kentucky and Auburn University shows that the residues have little effect on German cockroaches (Blattella germanica), ...

Philadelphia, August 14, 2024 – Researchers from the Center for Injury Research and Prevention (CIRP) at Children’s Hospital of Philadelphia (CHOP) found discrepancies between crash reports and hospital data that might paint an incomplete or inaccurate picture of how crashes impact the safety of child passengers. Enhancing the quality of injury data reported in crash reports can aid researchers in assessing the effectiveness of various transportation safety strategies for children. The findings were recently published by ...

August 14, 2024, TORONTO — A new round of awards from the Ontario Institute for Cancer Research (OICR) will jumpstart eight promising studies that could change how cancers are diagnosed and treated. OICR announced the results of its Pre-Clinical Acceleration Team Awards — part of the Institute’s Clinical Translational Pathway, which helps advance new discoveries so they can benefit people affected by cancer. The winning research teams are based across Ontario and are tackling some of the most common and hardest to treat cancers. They are developing solutions to find cancer earlier, diagnose it more ...

MIAMI (August 14, 2024) – Communities impacted by increased wildfire activity and smoke can use a population health-based action plan to help alleviate health risks, particularly for those with chronic obstructive pulmonary disease (COPD) and asthma, according to a new perspective article. The article is published in the July 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal. COPD is an inflammatory lung disease, comprising several conditions, ...

UNIVERSITY PARK, Pa. — Early life exposure to ‘forever chemicals’ in the environment permanently disrupts the gut microbiome in mice, contributing to the development of metabolic disease in later life, according to new research led by Penn State. The results, published today (Aug. 14) in the journal Environmental Health Perspectives, suggest that human exposure to these chemicals during early childhood may be contributing to the recent epidemic of metabolic disorders, including obesity and type 2 diabetes among adults. The researchers focused specifically on 2,3,7,8-tetrachlorodibenzofuran ...

Over the course of nearly five months in 2022, NASA's Perseverance rover collected rock samples from Mars that could rewrite the history of water on the Red Planet and even contain evidence for past life on Mars. But the information they contain can't be extracted without more detailed analysis on Earth, which requires a new mission to the planet to retrieve the samples and bring them back. Scientists hope to have the samples on Earth by 2033, though NASA's sample return mission may be delayed. "These samples are the reason why our mission was flown," said paper ...

Among the many devasting impacts in the aftermath of a hurricane are power outages, which can take days or even weeks to restore. Communities grappling with the loss of electricity may encounter obstacles in accessing vital services, including food, fuel and health care. In 2018, Hurricane Michael, a Category 5 storm, wreaked havoc in Florida as it made landfall in the United States. It was strongest recorded to hit the Florida Panhandle with winds of nearly 161 miles per hour and storm surge reaching heights ...

In 2017, the Minamata Convention on Mercury went into effect, designed to help curb mercury emissions and limit exposure across the globe. However, a new study of mercury levels in soil suggests that the treaty’s provisions might not be enough. The study published in ACS’ Environmental Science & Technology estimates that soil stores substantially more mercury than previously thought, and it predicts that increases in plant growth due to climate change may add even more. Mercury is a persistent environmental pollutant, moving through air, water and soil, and accumulating within plants ...

Noble gases have a reputation for being unreactive, inert elements, but more than 60 years ago Neil Bartlett demonstrated the first way to bond xenon. He created XePtF6, an orange-yellow solid. Because it’s difficult to grow sufficiently large crystals that contain noble gases, some of their structures — and therefore functions — remain elusive. Now, researchers have successfully examined tiny crystallites of noble gas compounds. They report structures of multiple xenon compounds in ACS Central ...

Cancer is a complex disease characterized by uncontrolled cell growth, significantly impacting global health. Head and neck cancers rank as the sixth most prevalent cancers worldwide, with a higher incidence in South-central Asia. Oral squamous cell carcinoma (OSCC) is the predominant malignancy in this category, posing a significant health concern due to its high mortality and often late-stage diagnosis. The significance of early detection and appropriate screening measures cannot be overstated, as they play a pivotal role in improving survival rates and reducing the disease burden. Overview ...

In collaboration with the Tianqiao and Chrissy Chen Institute, the American Association for the Advancement of Science (AAAS) is announcing the establishment of the Chen Institute and Science Prize for Al Accelerated Research. Submissions are now open for the first year of the prize, which will be awarded in 2025. The prize will recognize young researchers who apply techniques in artificial intelligence (AI) – such as machine learning, natural language processing, or computer vision – to help the life sciences research community solve important problems and accelerate their work. Successful applicants will have made a fundamental advance that would not have been ...

More efficient and longer-lasting fuel cells are essential for fuel cell-powered heavy-duty hydrogen vehicles to be an alternative to combustion fuelled counterparts. Researchers at Chalmers University of Technology, Sweden, have developed an innovative method to study and understand how parts of fuel cells degrade over time.  This is an important step towards the improved performance of fuel cells and them becoming commercially successful. Hydrogen is a fuel alternative that is becoming increasingly interesting for heavy-duty vehicles.  Hydrogen-powered vehicles only emit water vapour as exhaust, and if the hydrogen is produced using renewable energy, it is completely free ...

A new, air-powered computer sets off alarms when certain medical devices fail. The invention is a more reliable and lower-cost way to help prevent blood clots and strokes — all without electronic sensors. Described in a paper in the journal Device, the computer not only runs on air, but also uses air to issue warnings. It immediately blows a whistle when it detects a problem with the lifesaving compression machine it is designed to monitor. Intermittent pneumatic compression or IPC devices are leg sleeves that fill with air periodically and ...

PULLMAN, Wash. – Evaluators who want to avoid appearing prejudiced may overcorrect and give women inflated performance feedback, new research indicates, which is a practice that could ultimately hinder their ability to improve and advance. A Washington State University-led research team investigated the connection between overly positive performance reviews and “protective paternalism,” the belief that women need to be handled carefully and shielded from harm. While it may be well-intentioned, ...

A new study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also plays a crucial role in gene regulation. This study demonstrates that both the linear sequence of DNA and its three-dimensional configuration are linked to friendly behavior shaped by dog domestication, providing new insights into the molecular mechanisms underlying social traits. Behavioral traits such as sociability are influenced by numerous genes, their interactions, environmental factors, and individual life experiences. Because ...

Research Highlights: Adults in white-collar jobs in Canada with high job strain and for whom significant efforts are met with low rewards (such as low salary or recognition) may face a 97% increased risk for developing the irregular heart rhythm condition known as atrial fibrillation, or AFib or AF, compared to workers not exposed to these work stressors. Separately, high job strain alone was associated with an 83% higher risk of developing AFib, and effort-reward imbalance alone was associated with a 44% greater risk. Recognizing and addressing these stressors at work may be an effective strategy ...

If it’s ever felt like everything in your body is breaking down at once, that might not be your imagination. A new Stanford Medicine study shows that many of our molecules and microorganisms dramatically rise or fall in number during our 40s and 60s. Researchers assessed many thousands of different molecules in people from age 25 to 75, as well as their microbiomes — the bacteria, viruses and fungi that live inside us and on our skin — and found that the abundance of most molecules ...

The COVID-19 pandemic and the lockdown measures to prevent contagion resulted in extensive disruptions in children’s and adolescents’ everyday lives. A new study in Child Development from the Aarhus University Hospital in Denmark, University of California, Riverside and University of California, Davis in the United States, investigated personal memories (i.e., memories for episodes experienced in one’s own life) about the first lockdown in Denmark in Spring 2020 among children and adolescents and how this may have impacted their psychological well-being over the following year.  For context, in ...

CLEVELAND, Ohio (August 14, 2024)—With more than 24 million people globally living with dementia without a cure in sight, there is a lot of focus on ways to prevent and delay cognitive impairment. A new study suggests that severe menopause symptoms such as hot flashes and depression can negatively affect cognitive function in postmenopausal women. Results of the study are published online today in Menopause, the journal of The Menopause Society. In conjunction with our aging population, dementia diagnoses are on the rise. It ...