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Advanced MRI scans help identify one in three concussion patients with ‘hidden disease’
Medicine 2024-08-09

Advanced MRI scans help identify one in three concussion patients with ‘hidden disease’

Offering patients with concussion a type of brain scan known as diffusion tensor imaging MRI could help identify the one in three people who will experience persistent symptoms that can be life changing, say Cambridge researchers. Around one in 200 people in Europe every year will suffer concussion. In the UK, more than 1 million people attend Emergency Departments annually with a recent head injury. It is the most common form of brain injury worldwide. When a patient in the UK presents at an Emergency Department with head injury, they ...
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Medicine 2024-08-09

Psychological bias links good deeds to a belief in God, research says

Experiments conducted by UC Merced researchers find that people who perform good deeds are far more likely to be thought of as religious believers than atheists. Moreover, the psychological bias linking kindness and helpfulness with faith appears to be global in scale. Research on the mental link between moral behavior and religious belief goes back more than a decade. Prior research, however, emphasized the dark side of this equation, with participants asked whether they assumed it was more probable that a serial killer believed in God or was an atheist (people in nations all over the planet thought the latter ...
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Environment 2024-08-09

Greenland megatsunami led to week-long oscillating fjord wave

In September 2023, a megatsunami in remote eastern Greenland sent seismic waves around the world, piquing the interest of the global research community. The event created a week-long oscillating wave in Dickson Fjord, according to a new report in The Seismic Record. Angela Carrillo-Ponce of GFZ German Research Centre for Geoscience and her colleagues identified two distinct signals in the seismic data from the event: one high-energy signal caused by the massive rockslide that generated the tsunami, and one very long-period (VLP) signal that lasted over a week. Their analysis of the VLP signal—which was detected as far as 5000 kilometers away—suggests ...
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Medicine 2024-08-08

Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy

Gene therapy could potentially cure genetic diseases but it remains a challenge to package and deliver new genes to specific cells safely and effectively. Existing methods of engineering one of the most commonly used gene-delivery vehicles, adeno-associated viruses (AAV), are often slow and inefficient.  Now, researchers at the Broad Institute of MIT and Harvard have developed a machine-learning approach that promises to speed up AAV engineering for gene therapy. The tool helps researchers engineer the protein shells of AAVs, called capsids, to have multiple desirable ...
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Medicine 2024-08-08

Bacteria encode hidden genes outside their genome—do we?

NEW YORK, NY (Aug. 8, 2024) -- Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene’s code affect health. This linear rule of life was thought to govern all forms of life—from humans down to bacteria. But a new study by Columbia researchers shows that bacteria break that rule and can create free-floating and ephemeral genes, raising the possibility that similar genes exist outside ...
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Assistant professor's $1.1M NASA grant to develop computational tool aiding hypersonic vehicle design
Technology 2024-08-08

Assistant professor's $1.1M NASA grant to develop computational tool aiding hypersonic vehicle design

STARKVILLE, Miss.—NASA is awarding a Mississippi State University assistant professor a $1.13 million grant to develop a new simulation tool to aid the design of hypersonic vehicles used in space exploration. Vilas Shinde of MSU’s Department of Aerospace Engineering won the grant to develop a new flow stability and transition analysis tool, which will aid researchers and aircraft designers in understanding and predicting changes associated with the boundary layer—air flow in the vicinity of an aircraft’s ...
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Medicine 2024-08-08

Houston Methodist study shows new, more precise way to deliver medicine to the brain

Houston Methodist researchers have discovered a more accurate and timely way to deliver life-saving drug therapies to the brain, laying the groundwork for more effective treatment of brain tumors and other neurological diseases. In a study published this month in Communications Biology, an open access journal from Nature Portfolio, investigators used an electric field to infuse medicine from a reservoir outside the brain to specific targets inside the brain. This adds a new dimension to the 30-year-old process of injecting therapeutics into the brain through ...
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Science 2024-08-08

A ‘thank you’ goes a long way in family relationships

URBANA, Ill. – You’ve probably heard that cultivating gratitude can boost your happiness. But in marriage and families, it’s not just about being more grateful for your loved ones — it’s also important to feel appreciated by them. Researchers at the University of Illinois Urbana-Champaign have previously explored the positive impact of perceived gratitude from romantic partners for couples’ relationship quality. In a new study, they show the benefits of perceived gratitude ...
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Science 2024-08-08

How a legal loophole allows unsafe ingredients in US foods

The Food and Drug Administration (FDA) is tasked with overseeing the safety of the U.S. food supply, setting requirements for nutrition labeling, working with companies on food recalls, and responding to outbreaks of foodborne illness. But when it comes to additives already in our food and the safety of certain ingredients, FDA has taken a hand-off approach, according to a new article in the American Journal of Public Health. The current FDA process allows the food industry to regulate itself when it comes to thousands of added ...
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Medicine 2024-08-08

USC researchers develop AI model that predicts the accuracy of protein–DNA binding

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments. The tool, called Deep Predictor of Binding Specificity (DeepPBS), is a geometric deep learning model designed to predict protein–DNA binding specificity from protein–DNA complex structures. DeepPBS ...
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Increasing solid-state electrolyte conductivity and stability using helical structure
Science 2024-08-08

Increasing solid-state electrolyte conductivity and stability using helical structure

Solid-state electrolytes have been explored for decades for use in energy storage systems and in the pursuit of solid-state batteries. These materials are safer alternatives to the traditional liquid electrolyte—a solution that allows ions to move within the cell—used in batteries today. However, new concepts are needed to push the performance of current solid polymer electrolytes to be viable for next generation materials. Materials science and engineering researchers at the University of Illinois Urbana-Champaign have explored the role of helical secondary structure on the conductivity of solid-state peptide polymer ...
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The threat of mpox has returned, but public knowledge about it has declined
Science 2024-08-08

The threat of mpox has returned, but public knowledge about it has declined

PHILADELPHIA – It has been two years since the World Health Organization declared a global health emergency over an outbreak of mpox, a disease endemic to Africa that had spread to scores of countries. Now, in the summer of 2024, a deadlier version of the infectious disease has spread from the Democratic Republic of Congo to other African nations, the strain that originally hit the United States has shown signs of a resurgence, and this week the Centers for Disease Control and Prevention (CDC) issued a new alert on mpox to health care providers. But while the American public quickly learned about the disease during the summer of 2022, as ...
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Medicine 2024-08-08

How does traumatic brain injury progress to Alzheimer’s disease?

RIVERSIDE, Calif. -- A traumatic brain injury, or TBI, is caused by a contusion to the head that may result in injury to the brain. This type of injury combined with the inherited genetic risk factors can result in the accelerated development of Alzheimer’s disease and related dementia, or ADRD. TBIs range from mild to severe, with the majority being mild. They are especially common in adolescents engaging in contact sports and in the elderly who tend to fall with greater frequency as they age. Regardless of the source, TBI and how it progresses to ADRD is an understudied area of research. A $3.5 million grant to the University of California, ...
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Researchers find unexpectedly large methane source in overlooked landscape
Science 2024-08-08

Researchers find unexpectedly large methane source in overlooked landscape

When Katey Walter Anthony heard rumors of methane, a potent greenhouse gas, ballooning under the lawns of fellow Fairbanks residents, she nearly didn’t believe it. “I ignored it for years because I thought ‘I am a limnologist, methane is in lakes,’” she said. But when a local reporter contacted Walter Anthony, who is a research professor at the Institute of Northern Engineering at University of Alaska Fairbanks, to inspect the waterbed-like ground at a nearby golf course, she started to pay attention. Like others in Fairbanks, they lit “turf bubbles” on fire and confirmed the presence of methane ...
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Royal Commission for AlUla collaborates with SETI Institute to support development of Alula Manara Observatory
Science 2024-08-08

Royal Commission for AlUla collaborates with SETI Institute to support development of Alula Manara Observatory

Royal Commission for AlUla Collaborates with SETI Institute to Support Development of AlUla Manara Observatory   Experts from SETI Institute will support the advancement of telescope technology and data analysis at AlUla Manara Observatory.  The collaboration will enhance the future observatory's capabilities as it welcomes global scientists, researchers, and tourists interested in astronomy and space science. Ambitions to foster curiosity, knowledge sharing, and upskilling local capabilities in astronomical and space sciences field Mountain View, CA , 8 August 2024 -- The Royal Commission for AlUla (RCU) and SETI Institute ...
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Cutting a few calories won’t hurt your workout
Science 2024-08-08

Cutting a few calories won’t hurt your workout

A new UC Riverside study demonstrates that calorie restriction doesn’t deter mice from exercising, challenging the belief that dieting drains workout energy. The study, published in the journal Physiology & Behavior, shows that cutting calories by 20% did not significantly reduce the distance that mice voluntarily chose to run each day.  The researchers set out to understand what happens to mice when the amount of food available to them is reduced.  The findings, they hoped, would be relevant ...
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Study reveals ways in which 40Hz sensory stimulation may preserve brain’s ‘white matter’
Medicine 2024-08-08

Study reveals ways in which 40Hz sensory stimulation may preserve brain’s ‘white matter’

Early-stage trials in Alzheimer’s disease patients and studies in mouse models of the disease have suggested positive impacts on pathology and symptoms from exposure to light and sound presented at the “gamma” band frequency of 40 Hz. A new study zeroes in on how 40Hz sensory stimulation helps to sustain an essential process in which the signal-sending branches of neurons, called axons, are wrapped in a fatty insulation called myelin. Often called the brain’s “white matter,” myelin protects axons and insures better ...
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Record-breaking recovery of rocks that originated in Earth’s mantle could reveal secrets of planet’s history
Space 2024-08-08

Record-breaking recovery of rocks that originated in Earth’s mantle could reveal secrets of planet’s history

Scientists have recovered the first long section of rocks that originated in the Earth’s mantle, the layer below the crust and the planet’s largest component. The rocks will help unravel the mantle’s role in the origins of life on Earth, the volcanic activity generated when it melts, and how it drives the global cycles of important elements such as carbon and hydrogen, according to the team. The nearly continuous 1,268 metres of mantle rock was recovered from a “tectonic window,” a section ...
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Medicine 2024-08-08

Surprise: infected bacteria fight back with “hidden” genes that halt cell growth, slow viral spread

Researchers have uncovered a surprising way bacteria defend themselves: when a bacterium is infected, bacterial enzymes that copy genetic information from RNA into DNA synthesize genes whose protein products help shut down cell growth. This prevents further viral spread in the neighboring bacterial population. The results highlight the potential for other “hidden” genes, like the one found here, to be unearthed in different biological contexts. Bacteria defend themselves from viral ...
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Medicine 2024-08-08

Early prenatal exposure to famine increases Type 2 diabetes risk in adulthood, shows study of historical Ukraine event

Prenatal exposure to famine significantly increases the risk of developing Type 2 diabetes mellitus (T2DM) in adulthood, according to a new study of people impacted by the 1932-1933 Holodomor famine in Ukraine. While the immediate and short-term effects of famines on mortality and morbidity are well-documented, deciphering famines’ long-term health consequences – as this study did – has been more difficult. Previous research has suggested a link between prenatal nutrition and adult health ...
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Environment 2024-08-08

Marine algae use massive enzymes of unprecedented size to biosynthesize fish-killing toxins

Marine algae Prymnesium parvum use massive enzymes dubbed PKZILLAs – some of the largest proteins ever to be identified in nature – to make large and complex prymnesin neurotoxins responsible for mass fish kills during harmful algal blooms worldwide, researchers report. “The discovery and initial characterization of the prymnesin PKZILLA gigasynthases now elucidates the long-standing question about how microalgae biosynthesize their giant polyketide polyether molecules,” write the authors. It also expands ...
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Earth Science 2024-08-08

Record-breaking 1.2-kilometer drill core unveils new insights into Earth's mantle

A record-breaking 1268-meter drill core into Earth’s mantle, collected from the Mid-Atlantic Ridge in the North Atlantic, has provided a deep and detailed mineralogical glimpse of the oceanic mantle. The findings reveal new insights into mantle composition, Earth’s deep geology, and the potential biogeochemical conditions involved in the origins of life. Understanding the Earth’s mantle is crucial for comprehending important details of the Earth system, including terrestrial magmatism, crust formation, and the cycling ...
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Medicine 2024-08-08

American College of Cardiology issues guide for managing in-patient heart failure

The American College of Cardiology has issued updated guidance on managing patients hospitalized for heart failure (HF) to provide a decision-making pathway that tailors therapy to clinical trajectory to better manage disease. The updated Expert Consensus Decision Pathway incorporates the latest evidence to provide guidance for clinicians to use at the point of care in conjunction with the 2022 ACC/AHA Heart Failure Guideline. Heart failure refers to several conditions that can affect the way the heart works, its structure or both. Over time, heart failure makes ...
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Medicine 2024-08-08

Type 2 diabetes cases more than doubled seven decades after exposure to famine

Researchers at Columbia University Mailman School of Public Health, the University of North Carolina at Chapel Hill and at the National Academy of Sciences of Ukraine used the setting of the man-made Ukrainian Holodomor famine of 1932-1933 to examine the relation between prenatal famine and adult Type 2 diabetes mellitus (T2DM). They studied 128,225 Type 2 diabetes cases diagnosed between 2000-2008 among 10,186,016 male and female Ukrainians born between 1930 and 1938. Individuals who were exposed in early gestation to the famine had a more than two-fold likelihood of developing Type 2 diabetes compared to those ...
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Science 2024-08-08

Millions of years for plants to recover from global warming

In brief: Disruption of the functioning of vegetation due to warming can lead to the failure of climate regulating mechanisms for millions of years. Vegetation changes can alter the planet’s climate equilibrium. Geological and climatic history provide insight into the effects of global warming today. Scientists often seek answers to humanity’s most pressing challenges in nature. When it comes to global warming, geological history offers a unique, long-term perspective. Earth’s geological ...
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