Association of radiation facility volume with survival for men with very high-risk prostate cancer
2023-08-08
About The Study: The findings of this study suggest that the expertise and resources that accompany high-volume treatment facilities are associated with improved outcomes for men with very high-risk prostate cancer, but further investigation is needed to identify the specific causes for this association.
Authors: Sagar A. Patel, M.D, of Emory University in Atlanta, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi: ...
Management of acetaminophen poisoning in the US and Canada
2023-08-08
About The Study: This study provides a consensus statement on consistent evidence-based recommendations for medical, pharmacy, and nursing education and practice to optimize care of patients with acetaminophen poisoning.
Authors: Richard C. Dart, M.D., Ph.D., of the University of Colorado School of Medicine in Denver, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi: 10.1001/jamanetworkopen.2023.27739)
Editor’s Note: Please ...
Study finds women who consumed sugar sweetened beverage daily had higher risk of developing liver cancer and chronic liver disease
2023-08-08
Approximately 65% of adults in the United States consume sugar sweetened beverages daily. Chronic liver disease is a major cause of morbidity and mortality worldwide and can result in liver cancer and liver disease-related mortality. Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, led one of the first studies to look at the association between intake of sugar-sweetened beverages, artificially sweetened beverages, and incidence of liver cancer and chronic liver disease mortality. Results are published in JAMA.
“To our knowledge, ...
How to increase acceptance of an RSV vaccine? Explain the FDA’s vaccine approval process
2023-08-08
PHILADELPHIA – A new study finds that people are more likely to recommend that a pregnant family member or friend get vaccinated to protect the infant from RSV illness if they are shown a chart outlining the rigorous process a vaccine undergoes to be approved by the Food and Drug Administration (FDA).
The experiment was conducted by an Annenberg Public Policy Center (APPC) team as part of a May 31-June 6, 2023, nationally representative panel survey on RSV, vaccination, and maternal health. Researchers found that 57% of those in a group exposed to a flowchart of the FDA vaccine approval process (see Appendix 1) were very or somewhat likely to recommend the RSV vaccine to a pregnant ...
Ammonia as a carbon-free hydrogen carrier for fuel cells: a perspective
2023-08-08
Due to the environmental and energy problems caused by fossil fuels, the search for alternative clean and renewable energy solutions has never been more urgent. Among these, hydrogen (H2) is emerging as a leading contender in the energy sector for both stationary and mobile applications. However, the commercial utilization of hydrogen fuel cells is hindered by the challenges of handling and transporting hydrogen due to its low volumetric energy density.
Fortunately, ammonia (NH3) is emerging as a promising hydrogen carrier due to its high hydrogen content (17.6 wt%) and potential economic benefits for energy production. When used as a fuel, it produces only ...
Elevated MRI enhancement ups cancer risk in women with very dense breasts
2023-08-08
OAK BROOK, Ill. – A machine learning model found that background parenchymal enhancement (BPE) on breast MRI is an indicator of breast cancer risk in women with extremely dense breasts, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA).
Women with extremely dense breasts are at a three- to six-times higher risk of developing breast cancer compared to women who have fatty breasts. Since mammography is less sensitive in detecting early-stage breast cancer in women with dense breasts, women between the ages ...
Does that MDS diagnosis need a second opinion?
2023-08-08
MIAMI, FLORIDA (EMBARGOED UNTIL AUG. 8, 2023 AT 10 A.M. ET) – Blood disorders known as myelodysplastic syndromes/neoplasms (MDS) are difficult to diagnose – and are commonly misdiagnosed – putting patients at increased risk for treatment mistakes and other potentially harmful consequences, according to researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations.
Their findings, published Aug. 8 in Blood Advances, a peer-reviewed journal of the American Society of Hematology, highlight the vital need for strong coordination between clinicians and skilled pathologists to ensure ...
Overlooked CO2 emissions induced by air pollution control devices in China's coal-fired power plants
2023-08-08
To combat this issue, China has implemented various environmental regulations, including the widespread use of air pollution control devices (APCDs) in CFPPs. While APCDs have successfully reduced air pollutants, their electricity consumption has led to indirect carbon dioxide (CO2) emissions. The extent of these CO2 emissions has remained uncertain, prompting researchers to delve deeper into this overlooked environmental concern.
In a new study published in Volume 17 of the journal Environmental Science and Ecotechnology, researchers from Shandong University conducted a study revealing that the proportion of APCD CO2 emissions in total ...
Brain stimulation improves walking in patients with Parkinson’s disease
2023-08-08
Gait-related disturbances adversely affect the quality of life of patients with Parkinson’s disease (PD), a condition affecting millions worldwide. Although various pharmacological, surgical, and rehabilitative treatments exist, their effectiveness is limited. Now, a team of researchers from Japan has successfully addressed this limitation. Using a novel neuromodulation approach that incorporates gait-combined closed-loop transcranial electrical stimulation, the team demonstrated significant gait improvements in patients with various neurological disorders including PD.
Parkinson’s disease ...
Creating pollen-free trees to combat hay fever
2023-08-08
Pollinosis, or hay fever, makes people miserable around the world, and Japanese cedar (Cryptomeria japonica) pollen is a significant cause of the suffering in the 38.8% of Japanese people who are allergic. Japanese cedar is also the country's most important timber species. A single mature tree produces on the order of three hundred million grains of pollen. Saneyoshi Ueno and colleagues investigated the genes required to produce this massive amount of genetic material. Previous research by Ueno’s team identified ...
SwRI launches Engine for Automatic Biomechanical Evaluation (ENABLE™) markerless analysis tool
2023-08-08
SAN ANTONIO — August 8, 2023 – Southwest Research Institute is launching its new Engine for Automatic Biomechanical Evaluation (ENABLE™) markerless biomechanics system during the American Society of Biomechanics (ABS) Annual Conference, August 8-11, in Knoxville, Tennessee. ABS attendees can see a demonstration by visiting Booth No. 11.
ENABLE is a user-friendly markerless motion capture system that leverages artificial intelligence, computer vision algorithms and biomechanical modeling. The key advantage of ENABLE is it efficiently captures ...
Spatial dimension of macrophage heterogeneity in liver diseases
2023-08-08
This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research.
The liver is a vital organ heavily populated with macrophages, which represent key players of the innate immune response but also hold key functions in the maintenance of a healthy organ. Liver macrophages are mostly distributed across two populations of different origins and functions during homeostasis and disease: liver resident macrophages (referred to as Kupffer cells, KCs), and monocytic macrophages derived from the bone-marrow (MoMFs). The KC: MoMF ratio, as well as their respective spatial distribution through the liver, are increasingly ...
Host adaptation drives genetic variation in Lyme disease bacteria
2023-08-08
A study looks at the mechanisms behind genetic variation in the bacteria that cause Lyme disease. Lyme disease is the most common vector-transmitted disease in the United States, with around 476,000 human cases annually. Most Lyme disease is caused by the bacteria Borrelia burgdorferi (Bb), which is transmitted by ticks and can infect a wide range of mammals and birds. Matthew Combs and colleagues analyzed the genetic diversity of Bb, specifically focusing on the pathogen’s outer surface protein C (ospC) gene, a well-known virulence factor that is essential for survival of the pathogen inside the tick and the early stages of infection in vertebrates. ...
Antimicrobial resistance poses threat in all 35 countries in the Americas
2023-08-08
***Embargo 14:00 UK / 10:00 BRT / 9:00 ET / 6:00 PT Tuesday, August 8, 2023***
SEATTLE, Wash. August 8, 2023 – 569,000 deaths were linked to bacterial antimicrobial resistance (AMR) in all 35 countries of the WHO Region of the Americas, according to a new peer-reviewed paper published in The Lancet Regional Health – Americas. This analysis on the burden of AMR in the Americas is the most comprehensive yet for the region, providing data for 35 countries, 23 bacterial pathogens, and 88 pathogen-drug combinations.
The ...
Parenting a 3-year-old robot
2023-08-08
Humans are social creatures and learn from each other, even from a young age. Infants keenly observe their parents, siblings or caregivers. They watch, imitate and replay what they see to learn skills and behaviors.
The way babies learn and explore their surroundings inspired researchers at Carnegie Mellon University and Meta to develop a new way to teach robots how to simultaneously learn multiple skills and leverage them to tackle unseen, everyday tasks. The researchers set out to develop a robotic AI agent with manipulation abilities equivalent to a 3-year-old child.
The team has announced RoboAgent, an artificial intelligence agent that leverages passive observations and active ...
Study compares youth detained for sex trafficking with more serious offenders
2023-08-08
Every year in the United States, about 1.7 million youth run away from home, which places them at risk for sex trafficking and prostitution. Sadly, most youth tend to fall victim to sex trafficking between the ages of 12 to 14.
While federal and state laws have been enacted to protect these runaway youth, they continue to be arrested, charged and detained for prostitution. Detaining youth who should not legally be considered offenders and who have extensive histories of victimization and mental health issues only exacerbates their underlying vulnerabilities that may have led them to run away or be sexually exploited in the first place.
There is ...
Insilico Medicine joins Montreal Chamber of Commerce to drive continued innovation
2023-08-08
Insilico Medicine (“Insilico”), a clinical stage generative artificial intelligence (AI) drug discovery company, has announced that it is now a member of the Chamber of Commerce of Metropolitan Montreal, demonstrating its commitment to the vibrant business community of Montreal and to fostering economic growth in the region. Insilico will officially launch its AI R&D Center in Montreal later this fall.
As a new member of the Chamber of Commerce of Metropolitan Montreal, Insilico brings its innovative expertise ...
'Crushing' chemical innovations at the heart of newly expanded NSF Center
2023-08-08
NEW YORK, August 8, 2023 — CUNY ASRC researcher Adam Braunschweig’s lab is part of a newly awarded $20 million center from the U.S. National Science Foundation to understand the atomic-scale mysteries of "crushing" chemistry. The multi-institutional award will establish the Center for the Mechanical Control of Chemistry (CMCC), which will conduct work to understand how the mechanical application of force can enable new advances in chemistry and make industrial processes cheaper and more environmentally friendly.
“I’m excited that my lab is playing a part in research ...
Bighorn sheep associations: understanding tradeoffs of sociality and implications for disease transmission
2023-08-08
Sociality plays a pivotal role in the lives of many animal species, influencing mating success, survival rates, and susceptibility to diseases. In the challenging environment of bighorn sheep populations, sociality is believed to have evolved for its fitness benefits. However, the delicate balance of costs and benefits associated with sociality can vary at different scales, leading to diverse interpretations of animal behavior.
New research titled "Bighorn sheep associations: understanding tradeoffs of sociality and implications for disease transmission" has been published in PeerJ Life & Environment. The study, ...
Lead poisoning from Ayurvedic medicines: rare but cautionary
2023-08-08
An article in CMAJ (Canadian Medical Association Journal) highlights a case of lead toxicity from Ayurvedic medicines in a young woman, and the complexity in diagnosing the rare condition https://www.cmaj.ca/lookup/doi/10.1503/cmaj.230592.
"Given that lead toxicity is uncommon and its presentation nonspecific, patients are often seen by many health care providers before the diagnosis is made," writes Dr. Julian Gitelman, Dalla Lana School of Public Health, University of Toronto, with coauthors. "A careful exposure history is essential to suggest the diagnosis."
The patient, a 39-year-old woman, visited the emergency department 3 times in 6 weeks ...
Holidaymakers be warned: Short, intense sun-seeking trips can disrupt skin’s microbiome
2023-08-08
Skin, the largest organ of the human body, is home to a vast array of bacteria, fungi, and viruses – microorganisms that compose the skin microbiota. Among other things, these microbial populations, which are organized in complex community structures, protect against pathogens.
Prolonged exposure to UVR is associated with damage to DNA in skin cells, inflammation, and premature skin aging, yet intentional sun-seeking behaviors remain common.
Due to a lack of studies focusing on how individual behavior influences UVR-associated microbiota shifts, and how this may relate to skin health, ...
New Antarctic extremes ‘virtually certain’ as world warms
2023-08-08
Extreme events in Antarctica such as ocean heatwaves and ice loss will almost certainly become more common and more severe, researchers say.
With drastic action now needed to limit global warming to the Paris Agreement target of 1.5°C, the scientists warn that recent extremes in Antarctica may be the tip of the iceberg.
The study reviews evidence of extreme events in Antarctica and the Southern Ocean, including weather, sea ice, ocean temperatures, glacier and ice shelf systems, and biodiversity on land and sea.
It concludes that Antarctica’s fragile environments “may well be subject to considerable stress and ...
Three-dimensional printing achieves precision light control for structural coloration
2023-08-08
The world's first 3D printing technology that can be used in transparent displays and AR devices has been developed, which implements the physical phenomenon of chameleon's changing skin color or peacock's beautiful feather color.
Dr. Jaeyeon Pyo’s team at KERI has succeeded in realizing a three-dimensional diffraction grating that can precisely control the path of light based on 'nanoscale 3D printing technology'. This is a novel technology that can utilize the principle of structural color observed in nature ...
Well-designed digital health platforms can improve the quality of life for people with Parkinson’s disease and their caregivers
2023-08-08
Philadelphia, August 8, 2023 – There is a need to better deliver information on medical nutrition therapy for patients with Parkinson’s disease (PD). Findings of a new study in the Journal of Nutrition Education and Behavior, published by Elsevier, show digital health serves as an additional health service resource, which increases the healthcare provider’s abilities to collect current visual and objective data, thereby decreasing patient and caregiver burden and medical expenses.
Lead author Dara Lyn LoBuono, PhD, RD, assistant professor in health and exercise science at Rowan ...
Bat activity lower at solar farm sites, study finds
2023-08-08
The activity level of six bat species was significantly reduced at solar farm sites, researchers have observed.
Their findings, published today in Journal of Applied Ecology, have the potential to impact and inform planning legislation and policy so that the benefits of solar power are reaped without impacting wildlife.
Renewable technologies are important in meeting energy demands sustainably. This is of vital importance given the roles of fossil fuels in producing carbon dioxide, a key driver of climate change. Renewable energy is growing at a rapid pace globally, with solar photovoltaic power ...
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