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Environment 2024-08-05

DRI’s STEM education team receives EPA grant to support microplastics education for Nevada students and communities

Reno, Nev. (August 5, 2024) – DRI’s STEM Education Team has received a grant from the Environmental Protection Agency (EPA) to support environmental education in Nevada’s schools. The $100,000 grant will fund the production of additional educational kits known as Greenboxes that raise awareness and understanding of the prevalence and role of microplastics in the environment. “DRI is honored to be awarded this EPA grant, and we are eager to continue our outreach to underserved rural and urban communities across Nevada,” said DRI STEM Education Program Manager Emily McDonald-Williams. “Middle school students ...
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Sex bias in pain management at emergency departments new study reveals
Science 2024-08-05

Sex bias in pain management at emergency departments new study reveals

New study reveals a significant sex bias in pain management at emergency departments, showing that female patients are consistently less likely to receive pain medication prescriptions compared to male patients with similar complaints. This bias persists across different ages, pain levels, and physician sex, indicating a systemic issue. Female patients' pain scores are less frequently recorded, and they spend more time in the emergency department than male patients. The findings highlight the need for urgent policy interventions and training for healthcare ...
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Medicine 2024-08-05

Child Mind Institute paper reveals next frontier in reproducible brain imaging for neuroscience discovery

New York, NY (August 5, 2024) — The Child Mind Institute has released a paper detailing their pioneering study in the journal Nature Human Behaviour titled, "Moving Beyond Processing and Analysis-Related Variation in Resting State Functional Brain Imaging." The research identifies significant challenges in the reproducibility and standardization of functional magnetic resonance imaging (fMRI) used to understand brain function and behavior — and proposes concrete solutions to move the field towards results that translate into real world impact. Along with a diverse team of international collaborators, ...
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Hospital pneumonia diagnoses are uncertain, revised more than half the time, study finds
Medicine 2024-08-05

Hospital pneumonia diagnoses are uncertain, revised more than half the time, study finds

Pneumonia diagnoses are marked by pronounced uncertainty, an AI-based analysis of over 2 million hospital visits has found. More than half the time, a pneumonia diagnosis made in the hospital will change from a patient’s entrance to their discharge—either because someone who was initially diagnosed with pneumonia ended up with a different final diagnosis, or because a final diagnosis of pneumonia was missed when a patient entered the hospital (not including cases of hospital-acquired pneumonia). The study describing the new results publishes August 6th in Annals of Internal Medicine. Barbara Jones, MD, MSCI, pulmonary and critical care physician ...
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Medicine 2024-08-05

Cancer screening estimated to cost $43 billion a year in the United States

Embargoed for release until 5:00 p.m. ET on Monday 5 August 2024     Annals of Internal Medicine Tip Sheet      @Annalsofim     Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.      ----------------------------     1. ...
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Medicine 2024-08-05

Researchers receive 9.5 million grant to study relationship between polyphenol intake, Alzheimer’s prevention, and the brain-gut-microbiome system

UCLA Health researchers, in collaboration with researchers from the Republic of Ireland and Northern Ireland, have received $9.5 million award from the National Institutes of Health (NIH) with support from European funding agencies — The Science Foundation Ireland (SFI) and the Public Health Agency Health & Social Care (HSC) — to study the effects of polyphenols on cognitive health and the brain-gut microbiome system. The proposal, named MAEVE, stands for “Microbiota mediated flavonoid metabolites for cognitive health.” In this interdisciplinary and multicenter study funded through the Tripartite US-Ireland Research & Development Partnership Program, ...
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UH astronomers uncover risks to planets that could host life
Space 2024-08-05

UH astronomers uncover risks to planets that could host life

A groundbreaking study has revealed that red dwarf stars can produce stellar flares that carry far-ultraviolet (far-UV) radiation levels much higher than previously believed. This discovery suggests that the intense UV radiation from these flares could significantly impact whether planets around red dwarf stars can be habitable. Led by current and former astronomers from the University of Hawaiʻi Institute for Astronomy (IfA), the research was recently published in the Monthly Notices of the Royal Astronomical Society. “Few stars have been thought to generate ...
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Environment 2024-08-05

An overlooked side-effect of the housing crisis may be putting Californians at increased risk from climate disasters

In a new article for the journal Proceedings of the National Academy of Sciences, UC Santa Cruz researchers laid out the foundation for their highly-anticipated upcoming study of how lack of affordable housing in urban areas of California may be driving increased development in and near wildlands, leading to more severe climate change impacts.  Since the 1990s, California has led the nation in the growth of Wildland-Urban Interface (WUI) development, with more than one in three households in the state now located immediately next to or within ...
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INT-1B3 miR-193a-3p mimic boosts t cell immunity and induces tumor cell death
Medicine 2024-08-05

INT-1B3 miR-193a-3p mimic boosts t cell immunity and induces tumor cell death

BUFFALO, NY- August 5, 2024 – A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, “INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death.” In this study, researchers Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu ...
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Technology 2024-08-05

Wayne State University professor receives NSF grant to study quantum tunneling

DETROIT — A Wayne State University professor recently received a three-year, $626,467 grant from the National Science Foundation’s Division of Physics. The project, “Probing Nonadiabatic Strong Field Ionization with Phase-Resolved Attoclock,” will research a quantum mechanical process known as quantum tunneling. Wen Li, Ph.D., professor of chemistry in Wayne State’s College of Liberal Arts and Sciences and his research team propose a new technique they have developed to study the process of quantum tunneling, a quantum mechanical phenomenon in which an object such as an electron or atom passes through ...
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Medicine 2024-08-05

Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer. Findings from the multicenter EXTEND trial, published today in the Journal of Clinical Oncology, were first presented at the 2024 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. At a median follow-up of 17.3 months, PFS was 10.3 months in patients who received metastasis-directed therapy (MDT) ...
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New method tracks how psychedelics affect neurons in minutes
Medicine 2024-08-05

New method tracks how psychedelics affect neurons in minutes

Researchers at the University of California, Davis have developed a rapid, noninvasive tool to track the neurons and biomolecules activated in the brain by psychedelic drugs. The protein-based tool, which is called Ca2+-activated Split-TurboID, or CaST, is described in research published in Nature Methods.  There has been mounting interest in the value of psychedelic-inspired compounds as treatments for brain disorders including depression, post-traumatic stress disorder and substance use disorder. Psychedelic ...
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Medicine 2024-08-05

Record number of drug overdoses in one year reported

August 4, 2024-- Drug-involved overdose deaths increased by over 500 percent in 2022 according to a study at Columbia University Mailman School of Public Health, with trends attributed to synthetic opioids. National data shows that fentanyl and heroin in particular attributed substantially to the rise particularly since 2014. However, the study also reports that income protection policies, can have a supportive role in preventing fatal drug overdoses. The findings are reported in the International ...
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Medicine 2024-08-05

Could this new drug turn back the clock on multiple sclerosis?

Could This New Drug Turn Back the Clock on Multiple Sclerosis? Ten years of work, and a little help from the green mamba snake, has resulted in a promising new drug that is already being tested in clinical trials. Multiple sclerosis (MS) degrades the protective insulation around nerve cells, leaving their axons, which carry electrical impulses, exposed like bare wires. This can cause devastating problems with movement, balance and vision; and without treatment, it can lead to paralysis, loss of independence and a shortened lifespan. Now, scientists at UC San Francisco and Contineum Therapeutics have developed a drug that spurs the body to replace the lost insulation, ...
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Greenland fossil discovery reveals increased risk of sea-level catastrophe
Environment 2024-08-05

Greenland fossil discovery reveals increased risk of sea-level catastrophe

The story of Greenland keeps getting greener—and scarier. A new study provides the first direct evidence that the center—not just the edges—of Greenland’s ice sheet melted away in the recent geological past and the now-ice-covered island was then home to a green, tundra landscape. A team of scientists re-examined a few inches of sediment from the bottom of a two-mile-deep ice core extracted at the very center of Greenland in 1993—and held for 30 years in a Colorado storage facility. They were amazed to discover ...
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New biomaterial regrows damaged cartilage in joints
Engineering 2024-08-05

New biomaterial regrows damaged cartilage in joints

Northwestern University scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large-animal model. Although it looks like a rubbery goo, the material is actually a complex network of molecular components, which work together to mimic cartilage’s natural environment in the body.  In the new study, the researchers applied the material to damaged cartilage in the animals’ knee joints. Within just six months, the researchers observed evidence of enhanced repair, including ...
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Science 2024-08-05

Horse miscarriages offer clues to causes of early human pregnancy loss

ITHACA, N.Y. – A study of horses – which share many important similarities with humans in their chromosomes and pregnancies – revealed that 42% of miscarriages and spontaneous abortions in the first two months of pregnancy were due to complications from an extra set of chromosomes, a condition called triploidy. “Over that embryonic period  [up to eight weeks from conception], triploidy had rarely been reported in mammals outside of women,” said Mandi de Mestre, professor of equine medicine at Cornell University. “The study tells us that over the first six weeks ...
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Hydraulic lift technology may have helped build Egypt’s iconic Pyramid of Djoser
Technology 2024-08-05

Hydraulic lift technology may have helped build Egypt’s iconic Pyramid of Djoser

The Pyramid of Djoser, the oldest of Egypt’s iconic pyramids, may have been built with the help of a unique hydraulic lift system, according to a study published August 5, 2024, in the open-access journal PLOS ONE by Xavier Landreau from CEA Paleotechnic Institute, France, and colleagues. The new study suggests that water may have been able to flow into two shafts located inside the pyramid itself, where that water could have been used to help raise and lower a float used to carry the building stones. The Pyramid of Djoser, also known as the Step Pyramid, is believed ...
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Medicine 2024-08-05

Honey added to yogurt supports probiotic cultures for digestive health

URBANA, Ill. – If you enjoy a bowl of plain yogurt in the morning, adding a spoonful of honey is a delicious way to sweeten your favorite breakfast food. It also supports the probiotic cultures in the popular fermented dairy product, according to two new studies from the University of Illinois Urbana-Champaign. “We were interested in the culinary pairing of yogurt and honey, which is common in the Mediterranean diet, and how it impacts the gastrointestinal microbiome,” said Hannah Holscher, associate professor in the Department of Food ...
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Tradition meets transformation for Maasai women
Technology 2024-08-05

Tradition meets transformation for Maasai women

Few communities reveal both the challenges and opportunities presented by cultural globalism more than Maasai communities in northern Tanzania. Traditionally pastoralists, the Maasai ethnic group’s social structure is historically patriarchal, with a man’s prestige measured by the size of his family and by the livestock he owns. The shrinking world has brought change: Urban centers and the promise of jobs are luring young Maasai from communities, and new technologies such as mobile phones are shifting social patterns and structures that ...
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Medicine 2024-08-05

Ochsner Health nurses named to the “Great 100 Nurses of Louisiana” 2024 List

NEW ORLEANS, La. – Ochsner Health proudly announces that 21 Ochsner nurses have been named to the 2024 Great 100 Nurses of Louisiana list by the Great 100 Nurses Foundation. This recognition highlights the contributions and commitment to excellence demonstrated by Ochsner’s nursing staff.  The Great 100 Nurses Foundation was established to honor nurses in Louisiana, North Carolina, Texas and Oklahoma. Each year, the foundation selects 100 nurses throughout Louisiana based on their concern for humanity, ...
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Improved chemokine homing enhances CAR T–cell therapy for osteosarcoma
Medicine 2024-08-05

Improved chemokine homing enhances CAR T–cell therapy for osteosarcoma

(MEMPHIS, Tenn. – August 5, 2024) Chimeric antigen receptor (CAR) T–cell immunotherapy re-engineers a patient’s immune cells to target cancer cells. While successful in some types of leukemia, the approach has yet to realize its potential against pediatric solid tumors. Scientists at St. Jude Children’s Research Hospital have identified a way to improve CAR T–cell homing – a T cell’s ability to navigate effectively to a tumor – for osteosarcoma. Improved homing is a necessary step in designing more successful CAR T–cell therapies. The results were published today in Clinical Cancer ...
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Medicine 2024-08-05

Forecasting climate’s impact on a debilitating disease

In Brazil, climate and other human-made environmental changes threaten decades-long efforts to fight a widespread and debilitating parasitic disease. Now, a partnership between researchers from Stanford and Brazil is helping to proactively predict these impacts.  Schistosomiasis, spread by freshwater snails, affects more than 200 million people in many tropical regions of the world. It can cause stomach pain and irreversible consequences such as enlarged liver and cancer. Public health officials worry that deforestation, rapid urban sprawl, and changing rainfall patterns – such as ...
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Medicine 2024-08-05

Deaths from advanced lung cancer have dropped significantly since immunotherapy became standard-of-care

Since the first immunotherapy drug to boost the body’s immune response against advanced lung cancer was introduced in the United States in 2015, survival rates of patients with the disease have improved significantly. That’s the conclusion of a recent real-world study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. For the research, a team led by Dipesh Uprety, MD, FACP, of the Barbara Ann Karmanos Cancer Institute and the Wayne State University School of Medicine, analyzed data from the National Cancer Institute Surveillance, Epidemiology, and End Results database, which compiles cancer-related data ...
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Science 2024-08-05

Air quality regimes around the world are playing catch up as science evolves and policy ambitions are too blunt, researchers say

The failure to co-ordinate legal, policy and scientific thinking risks “a squandering of opportunity” to improve air quality, concludes new environmental law research, co-led by a UCL academic.  In their Science paper, ‘Harnessing science, policy and law to deliver clean air’, Professors Eloise Scotford (UCL Faculty of Laws), Alastair Lewis (University of York) and Delphine Misonne  (UCLouvain Saint-Louis, Brussels) review recent research and highlight significant risks to achieving clean air globally. Despite significant achievements in air quality law and policy in some parts of the world ...
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