Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research. This powerful new technique, known as Protein-tag Degree of Labelling (ProDOL), provides a robust and versatile approach for precisely determining labelling efficiencies, the number of proteins that are labelled with fluorescent markers in living cells, in microscopy, a crucial aspect of protein quantification in biological research. The method ...

Since the industrial revolution, microbes have successfully colonized one novel type of habitat after another: for example marine oil spills, plastic floating in the oceans, industrial brownfields, and even the interior of the International Space Station. However, it turns out that one extreme environment harboring a specialized community of highly adapted microbes is much closer to home: inside microwaves. This finding has now been reported for the first time in a study in Frontiers in Microbiology by researchers from Spain. It’s not only important from the perspective of ...

The Institute of Science and Technology Austria (ISTA) today announced it is investing in a state-of-the-art cluster of over 100 NVIDIA H100 Tensor Core GPUs to enhance its computing infrastructure and scale up machine learning for academic research. The latest-generation GPU cluster specializes in training large language models for generative AI and machine learning. The Institute-funded, multi-million investment helps accelerate AI research in the public sphere at scale and consolidates ISTA as a European computational hotspot. In the generative artificial intelligence (AI) era, AI research and ...

AUGUSTA, Ga. (Aug. 8, 2024) – With a new $11.3 million Program Project grant from the National Institutes of Health, experts from the Vascular Biology Center at the Medical College of Georgia at Augusta University are working to better understand the underlying mechanisms of cardiovascular disease. “Blood vessels are critical for the transport of oxygen, nutrients, and immune cells and when they don’t function properly it not only impacts the function of the heart, but other organs such as the lung, eye, brain ...

A new joint study by RMIT and the University of Bristol has revealed secrets to the remarkably steady flight of kestrels and could inform future drone designs and flight control strategies.   Watch video: YouTube  Making drones safer and more stable in turbulent conditions, or in cities where wind gusts from tall buildings make flying more difficult, makes applications like parcel delivery, food delivery and environmental monitoring more feasible, more often.     The study conducted in RMIT’s Industrial Wind Tunnel facility – one of the largest of its kind in ...

In a new study, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer’s disease by effectively jumpstarting the brain's memory circuitry.  If proven to have similar effects in humans, the candidate compound would be novel among Alzheimer’s disease treatments in its ability to revitalize memory and cognition, study authors said.   “There is really nothing like this on the market or experimentally that ...

TUCSON, Ariz., August 7, 2024 – Critical Path Institute (C-Path), whose mission is to lead collaborations that accelerate drug development, advancing better treatments for people worldwide, is proud to announce its inaugural C-Path Global Impact Conference (CGIC), taking place from September 9-11, 2024, at the Washington Marriott at Metro Center.  The conference represents a significant expansion of C-Path’s mission, focusing on critical areas of drug development. These areas highlight ...

Skin-to-skin cuddling with a parent has lasting cognitive benefits for premature babies, according to a new Stanford Medicine study. Preemies who received more skin-to-skin contact, also known as kangaroo care, while hospitalized as newborns were less likely to be developmentally delayed at 1 year of age, the study found. The research, which was published online July 11 in the Journal of Pediatrics, showed that even small increases in the amount of skin-to-skin time made a measurable difference in the babies’ neurologic development during their first year. “It’s ...

Ever since we learned that the surface of planet Mars is cold and dead, people have wondered if there is a way to make it friendlier to life.   In a groundbreaking study published Aug. 7 in Science Advances, researchers from the University of Chicago, Northwestern University, and the University of Central Florida have proposed a revolutionary approach towards terraforming Mars. This new method, using engineered dust particles released to the atmosphere, could potentially warm the Red Planet by more ...

A new global analysis of the dietary habits of children and adolescents from 185 countries revealed that youth, on average, consumed nearly 23% more sugar-sweetened beverages in 2018 compared to 1990. Overall, intakes were similar in boys and girls, but higher in teens, urban residents, and children of parents with lower levels of education. Researchers from the Friedman School of Nutrition Science and Policy at Tufts University published the findings Aug. 7 in The BMJ. The study drew from the Global Dietary Database, a large comprehensive compilation of what people around the world eat or drink, to generate the first global estimates and trends of sugar-sweetened ...

Children and adolescents across the world consumed on average 23% more sugar sweetened beverages (SSBs) in 2018 than they did in 1990, show the results of a study published in The BMJ today. Over the same period, a corresponding rise was seen in the prevalence of obesity among young people. Unhealthy diets, especially intake of sugar sweetened beverages, play a crucial role in obesity. Although tracking the consumption of these drinks by children and adolescents is essential to understanding ...

New evidence published by The BMJ today casts doubt on a much-hyped blood test for the NHS that promises to detect more than 50 types of cancer. The test, called Galleri, has been hailed as a “ground-breaking and potentially life-saving advance” by its maker, the California biotech company Grail, and the NHS is currently running a £150m Grail-funded trial of the test involving more than 100,000 people in England, report Dr Margaret McCartney and investigative journalist Deborah Cohen. NHS England claims the test can identify many cancers that “are difficult to ...

Providing radiotherapy after surgery could prevent breast cancer from returning in the same place for up to 10 years, a long-term study suggests. This protective effect is limited after a decade, when the risk of cancer recurrence is similar to that in those who have not received radiotherapy. The findings provide a more complete picture of the long-term benefits of radiotherapy following breast cancer surgery, experts say. Surgery followed by radiotherapy remains the standard care for women with ...

A new scientific review of 148 studies enrolling over 4.3 million adult chronic pain patients treated with prescription opioid painkillers has found that nearly one in ten patients experiences opioid dependence or opioid use disorder and nearly one in three shows symptoms of dependence and opioid use disorder.  This review provides a more accurate -- and more concerning -- rate of opioid misuse than has previously been calculated.  It was conducted by researchers at the University of Bristol, funded by the National Institute for ...

Mammoths, the massive pre-historic ice age cousins of the modern-day elephant, have always been understood to have inhabited parts of British Columbia, but the question of when has always been a bit woolly. Now, a new study from Simon Fraser University has given scientists the clearest picture yet when the giant mammals roamed Vancouver Island.   As part of SFU researcher Laura Termes’ PhD and published earlier this month in the Canadian Journal of Earth Sciences, the study examined 32 suspected mammoth samples collected on Vancouver Island. Of those samples, just 16 ...

Lafayette, La. – Ochsner Health is excited to announce that Mary Claire Curet, MD, is joining the team at St. Martinville Family Medicine, an Ochsner primary care practice. Dr. Curet, a native of New Iberia, is the first Ochsner Physician Scholar and brings a wealth of knowledge and a deep commitment to her community. “We are thrilled to welcome Dr. Curet to the Ochsner family,” said Leonardo Seoane, MD, Founding Dean of Xavier Ochsner College of Medicine and Executive Vice President and Chief Academic Officer for Ochsner Health. “Her dedication and passion for primary care, particularly in underserved ...

Researchers at Michigan State University have discovered two proteins that work together to determine the fate of cells in plants facing certain stresses. Ironically, a key discovery in this finding, published recently in Nature Communications, was made right as the project's leader was getting ready to destress. Postdoctoral researcher Noelia Pastor-Cantizano was riding a bus to the airport to fly out for vacation, when she decided to share a promising result she had helped gather a day earlier. “I didn’t want to wait ten days until I came back to send it. It took almost two years to get there,” said Pastor-Cantizano, who then worked ...

Irvine, Calif., Aug. 7, 2024 — From costing society an estimated $11 trillion to hindering new discoveries in medicine and preventing access to effective interventions, underrepresentation of women, older adults and minorities in clinical research has several significant consequences, according to recent analyses commissioned by the National Academies of Sciences, Engineering and Medicine.   Jonathan Watanabe, UC Irvine professor of clinical pharmacy practice and director of the campus’s Center for Data-Driven Drugs Research and Policy, ...

How do foraging animals find their food? A new study by New York University researchers shows that lemurs use smell, social cues, and long-term memory to locate hidden fruit—a combination of factors that may have deep evolutionary roots. “Our study provides evidence that lemurs can integrate sensory information with ecological and social knowledge, which demonstrates their ability to consider multiple aspects of a problem,” said anthropologist Elena Cunningham, a clinical professor of molecular pathobiology at NYU College of Dentistry and the lead author of the study, published in the International Journal of Primatology. Animals rely on ...

Scientists at the University of Akron and the University of Pittsburgh have overturned long-held assumptions in new research that finds water can be a help for adhesion. Dr. Ali Dhinojwala, distinguished W. Gerald Austen Endowed Chair and H.A. Morton Professor at The University of Akron’s School of Polymer Science and Polymer Engineering, lead a team whose significant breakthrough — that water can unexpectedly enhance adhesion under controlled conditions — was published Aug. 7 in Science Advances. The implications of this research are profound, particularly in biomedical applications ...

  The first-ever archeological survey in space has provided new insights into how astronauts use and adapt their living space on the International Space Station, which could influence the design of new space stations after the ISS is decommissioned.    Findings from the research team behind the International Space Station Archaeological Project (ISSAP) were published today in the journal PLOS ONE. Archaeologist Justin Walsh of Chapman University is available to discuss the discoveries of the team’s first on-orbit project, the Sampling Quadrangle Assemblages Research Experiment (SQuARE). While Earth-bound archaeologists dig one-meter squares to understand ...

BIRMINGHAM, Ala. – Over the course of life, memory fades with varying degrees, robbing older people of the ability to recollect personal experiences. This progressive, nearly inevitable process has long been hypothesized as a consequence of nature’s removal of dendritic spines, a key component of synapses, from brain neurons as they age. A study published in Science Advances led by researchers at the University of Alabama at Birmingham and Rush University Medical Center, Chicago, Illinois, now provides evidence that the preservation of past life experiences ...

Pregnant mothers have taken part in a clinical study (the UNITY trial) in Birmingham, which has found that nipocalimab, an investigational, fully human, monoclonal antibody, has the potential to improve the survival rate of unborn babies with rare, early-onset fetal anaemia, as a result of haemolytic disease of the fetus and newborn (EOS-HDFN).   The study investigated pregnancies complicated by severe EOS-HDFN (RhD (D) or Kell (K) alloimmunized pregnant individuals with singleton pregnancies) and evaluated the effects of nipocalimab at weekly intervals from 14-35 ...

AUSTIN, Texas — Data from a new investigational drug that could alter the standard treatment for a rare blood disease suggests it has the potential to delay or prevent anemia and the need for intrauterine blood transfusions in babies who are at high risk for the condition, known as Hemolytic Disease of the Fetus and Newborn (HDFN). Results of the Phase 2 clinical trial of the drug nipocalimab were published today in The New England Journal of Medicine. HDFN is a serious condition in which the blood types of the mother and her fetus do not match, potentially causing life-threatening anemia in the baby. The current ...

Organofluorine compounds — sometimes called ‘forever chemicals’ — are increasingly turning up in our drinking water, oceans and even human blood, posing a potential threat to the environment and human health. Now, researchers at The University of Texas at Austin have developed a way to fingerprint them, which could help authorities trace them to their source when they end up in aquifers, waterways or soil. The technique involves passing samples through a strong magnetic field then reading the burst of radio waves their atoms emit. This reveals ...