WASHINGTON—A vigorous workout does more to suppress hunger levels in healthy adults than does moderate exercise, and females may be especially susceptible to this response, according to a small study published in the Journal of the Endocrine Society. The study examines the effects of exercise intensity on ghrelin levels and appetite between men and women. Ghrelin is known as the “hunger hormone” and is associated with perceptions of hunger. “We found that high intensity exercise suppressed ghrelin levels more than moderate intensity exercise,” said lead author Kara Anderson, Ph.D., of the University ...

PLYMOUTH MEETING, PA [October 24, 2024] — New research published online-ahead-of-print in JNCCN—Journal of the National Comprehensive Cancer Network found that people with newly-diagnosed hormone receptor (HR)-negative, human epidermal growth factor receptor 2 (HER2)-positive breast cancer were more likely to receive timely, guideline-concordant treatment and have longer survival in states that participate in Medicaid expansion under the Affordable Care Act (ACA). A team of researchers—led by the American Cancer Society (ACS), and including Kathryn J. Ruddy, MD, MPH, of the Mayo Clinic ...

Decades after it was first found in Japan, a species of crustacean with unique black-and-white coloring that resembles a panda has been confirmed to be new to science. Melitid amphipods are shrimp-like crustaceans found worldwide. The newly classified Melita panda — named after the charismatic mammal — was first found in the 1990s. Details of the discovery and morphological analysis were published in a ZooKeys article on 21 September. The discovery of the Melita panda highlights the importance of studying species taxonomy, which is the naming and classification of organisms, for conservation efforts. It is impossible to know if a species is in ...

BOSTON (Oct. 24, 2024) – With the rise in incidence of food allergies in children in the past decade, there has been a corresponding increase in the need for professional psychology services due to increased anxiety. A new study being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston showed a more than 50% increase in psychology referrals at one center in 2023 compared to yearly referrals from 2018-2022. “Our center has devoted significant resources to address the psychosocial support needed by many families who have children with food allergies,” ...

BOSTON (Oct. 24, 2024) – Anaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary for those who encounter it. Two new studies being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston show it is not only patients and caregivers who misunderstand how best to treat anaphylaxis: emergency medical professionals often follow incorrect protocols for treating severe allergic reactions. “We know early recognition of anaphylaxis and treatment with epinephrine improves outcomes,” says Sasha Alvarado, DO, Co-Director of Quality ...

BOSTON (Oct. 24, 2024) – About 10% of Americans believe they are allergic to penicillin, and approximately 90% of those patients are not actually allergic. As a result, those with the penicillin allergy label are often prescribed more toxic, dangerous and expensive antibiotics that might not be necessary or effective. A new study being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston showed that syphilis patients labeled as penicillin allergic who are low risk should be delabeled to avoid treatment failure and other negative ...

BOSTON (Oct. 24, 2024) – In many cultures, it is common to burn incense for religious and cultural practices, including meditations, celebrations and spiritual and ancestral worship. A new medically challenging case being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston warns that, for those with allergies and asthma, health problems from burning incense can be a significant risk to adults and children. “Our patient was an 87-year-old woman with history of asthma and COPD, ...

BOSTON (Oct. 24, 2024) – Parents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heightened risk of developing food allergies. The desire to prevent food allergies causes some parents to consider elimination diets, cutting out certain foods from their child’s diet. A new study being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston showed that elimination diets in the case ...

BOSTON (Oct. 24, 2024) – Throughout the Covid pandemic, media widely reported that Black patients were more likely than White patients to refuse vaccines, including the influenza and Covid vaccines. A new study being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston showed that self-identified non-White patients were less likely to demonstrate vaccine-hesitancy than the self-identified White patient group. “We found ...

  BOSTON (Oct. 24, 2024) – Eosinophilic Esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of swallowing difficulties in children and adults. It affects about one in 2,000 people and is part of a spectrum of allergic conditions. A new study being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston investigated the probability of patients with certain atopic (allergic) conditions developing EoE. “We did a separate analysis of four common allergic conditions – asthma, allergic rhinitis, atopic dermatitis and food allergy – to determine ...

BOSTON (Oct. 24, 2024) – People have heard for years that climate change is having a significant impact on plant vegetation patterns and influencing how pollen and mold produce. A new study being presented at this year’s American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston showed that, in Chicago, there has been a significant increase in sensitization to pollens and molds in patients with nasal allergies. “Our goal was to analyze changes in pollen sensitization patterns ...

A single treatment with, a CRISPR-Cas9 based gene editing therapy, is enough to replace the daily medication of patients with hereditary angioedema (HAE), a condition characterized by severe, painful and sudden onset of swelling, sometimes resulting in death. Confirming the findings published earlier this year from researchers from Amsterdam UMC, the University of Auckland and Cambridge University Hospitals NHS Foundation Trust. This phase two study is published today in the New England Journal of Medicine and presented at American College of Allergy, Asthma & Immunology's annual congress on the ...

A collaborative research group, including researchers from Exploratory Research Center on Life and Living Systems and Institute for Molecular Science of National Institutes of Natural Sciences, as well as Nagoya City University, Nagoya University, and University of Tsukuba, has uncovered a new mechanism in the growth of amyloid β (Aβ) fibrils, which are closely associated with Alzheimer’s disease. Using advanced high-speed atomic force microscopy (HS-AFM), the team was able to observe Aβ fibril growth at the molecular ...

A new study1 from researchers at the Friedman School of Nutrition Science and Policy at Tufts University has found that consuming pistachios daily may significantly improve eye health by increasing macular pigment optical density (MPOD), due to the plant pigment lutein, a key factor in protecting the eyes from blue (visible) light and age-related damage. The randomized controlled trial showed that compared to eating a usual diet alone, eating 2 ounces (57 grams) of pistachios per day for 12 weeks as part of a usual diet resulted in a significant increase in MPOD in otherwise healthy middle-aged to older adults. MPOD is an important indicator of eye health, ...

Background and Aims Metabolic dysfunction-associated steatotic liver disease (MASLD) and its more advanced form, metabolic dysfunction-associated steatohepatitis, have emerged as the most prevalent liver diseases worldwide. Currently, lifestyle modification is the foremost guideline-recommended management strategy for MASLD. However, it remains unclear which detrimental signals persist in MASLD even after disease remission. Thus, we aimed to examine the persistent changes in liver transcriptomic profiles following ...

ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and Caris Life Sciences®(Caris) announced today a multi-year research collaboration wherein Caris is pairing its highly sophisticated and comprehensive genomic, transcriptomic and proteomic profiling, advanced artificial intelligence (AI) and machine learning algorithms with ECOG-ACRIN’s immense research capabilities. The first project is underway and leverages the tumor tissue samples from the Trial Assigning Individualized Options for Treatment (Rx) or TAILORx, breast cancer clinical trial. TAILORx is one of the world's largest breast cancer research resources. The TAILORx trial and its associated biospecimen ...

Self-assembling molecules into organized structures is highly valuable for developing new materials. One notable class of these materials is lyotropic chromonic liquid crystals (LCLCs), which are molecular assemblies of amphiphilic π-electronic molecules, with water-absorbing and water-repelling parts. The term “lyotropic” refers to liquid crystal phases that depend on the concentration of the molecules in a solvent, while “chromonic” indicates that these molecules are stacked into columnar assemblies. In a solvent, these structures are stabilized by π–π interactions and hydrophobic effects. Examples of ...

CLEVELAND—Researchers at the Case Western Reserve School of Medicine have found that, when compared to seven other anti-diabetic drugs, semaglutide, a popular diabetes and weight-loss drug, may lower the risk of Alzheimer’s disease in people with type 2 diabetes (T2D). Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills. According to the Alzheimer’s Association, nearly 7 million Americans 65 and older are living with the disease, and there are more deaths from Alzheimer’s than breast and prostate cancer combined. The study, published ...

A UNC Greensboro (UNCG) study following 299 women and their infants from pregnancy to toddlerhood examined mul ple psychological, biological, and social factors in the context of infants’ rapid weight gain. They found infant feeding practices associated with obesity, known as obesogenic practices, are strongly correlated with rapid infant weight gain.   Examples of obesogenic practices described in their recent Pediatric Obesity paper include watching television while feeding a baby, formula feeding, and supplementing a bottle with additional foods.   “The key take ...

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication. The computational tool is called PIONEER (Protein-protein InteractiOn iNtErfacE pRediction). Researchers demonstrated PIONEER’s utility by identifying potential drug targets for dozens of cancers and other complex diseases in a recently published Nature Biotechnology article. Genomic research is key in drug discovery, but it is not always enough on its own, says Feixiong Cheng, PhD, study co-lead author and director of Cleveland Clinic’s Genome Center. When ...

BUFFALO, N.Y. — The key to recovering from traumatic nerve injuries, like those sustained in motor vehicle accidents or gunshot wounds, may be a gene named for the land of everlasting youth in Irish folklore. In a study published today (Oct. 24) in Nature Communications, a University at Buffalo-led research team describes how the gene, called NANOG, can improve the regrowth of damaged nerves and re-establish innervation (the process of nerves growing and connecting with organs or tissues) after traumatic severing of peripheral nerves. The gene’s name is derived from Tír na nÓg, which is a mythical ...

If a phone or other electronic device was made of soft materials, how would that change its use? Would it be more durable? If hospital health monitoring equipment was made of less rigid components, would it make it easier for patients to wear? While electronics of that type may still be far in the future, Virginia Tech researchers have developed an innovative method for constructing the soft electronic components that make them up. The focus of a project from the team of Michael Bartlett, principal investigator and associate professor in the Department of Mechanical Engineering, ...

A study published today in IOP Publishing’s journal Environmental Research Letters, has revealed a staggering $79 billion in annual climate-related costs from the production of common materials in the United States. These costs, which stem from greenhouse gas emissions, are not reflected in current market prices, effectively creating a massive subsidy for carbon-intensive industries.  “High price point is a common reason why low emission alternative materials are not adopted voluntarily by industries. Accounting for the externalized cost of emissions could provide an economic basis for driving innovation and implementation of alternative material production ...

Houston, Texas – In a comprehensive review published in the October 2024 issue of Genomic Psychiatry, researchers have unveiled crucial insights into how two types of hormone receptors collaborate to maintain brain health and potentially prevent neurodegenerative diseases. The study, led by Professor Jan-Åke Gustafsson and colleagues at the University of Houston and Karolinska Institutet, demonstrates that liver X receptors (LXRs) and thyroid hormone receptors (TRs) work together in a previously unrecognized manner to regulate critical brain functions and protect ...

WASHINGTON, D.C. — OCTOBER 24, 2024 — Roughly four in five Americans say they either strongly (48%) or somewhat (31%) support a federal law that requires insurance companies to cover mental health at the same level they do medical or surgical care, including 95% of Democrats, 79% of independents and 67% of Republicans. Despite the widespread support, half of Americans (50%) have little to no trust that health insurers will comply with the law, according to a new West Health-Gallup survey released today. In 2020, less than half of all adults with mental illness received treatment, according to the White House, leading the Biden ...