New study highlights success of financial toxicity tumor board in reducing cancer treatment costs
2025-04-29
CHARLOTTE, N.C. – April 29, 2025 – Financial toxicity, the financial distress linked to cancer treatment, significantly impacts patient outcomes. To combat this, the Atrium Health Levine Cancer Institute established a Financial Toxicity Tumor Board in 2019.
The board is the first known institutional-level intervention of its kind, functioning like a traditional disease-focused multidisciplinary tumor board, but with a singular focus on financial distress. It includes participants from all areas of the cancer center ...
CAD/CAM shows clinical benefits in jaw reconstruction, reports Plastic and Reconstructive Surgery
2025-04-29
April 29, 2025 — For patients undergoing jaw reconstruction after surgery for head and neck cancer, computer-aided design and manufacturing (CAD/CAM) techniques can improve some key clinical outcomes, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.
"Our experience suggests that CAD/CAM techniques offer several benefits in patients undergoing free fibula ...
Missed school is an overlooked consequence of climate change
2025-04-29
In brief:
· Exposure to tropical cyclones during early childhood significantly reduces school enrollment.
· The effect is greater in areas unaccustomed to frequent storms.
· Girls shoulder an uneven share of the burden.
· Possible solutions include increased investment in disaster preparedness, resilient infrastructure, and community-based adaptation programs.
New Stanford-led research sheds light on an overlooked climate consequence: the impact of tropical cyclones on schooling opportunities and education in low- and ...
Reasons why anxiety and depression promote low self-belief revealed
2025-04-29
Researchers at UCL have uncovered why individuals who experience anxiety and depression often struggle with persistent low self-belief in their abilities.
A new study, published in Nature Communications, examined two large groups of people (230 and 278 participants) to measure their “confidence” when doing individual jobs and their “self-belief” when judging their overall performance of these individual jobs collectively.
They found that those with symptoms of anxiety and depression tended to build their overall self-belief by focusing their attention on jobs where ...
UMass Amherst graduate student’s discovery shows that even neutral molecules take sides when it comes to biochemistry
2025-04-29
AMHERST, Mass. — A new study led by a pair of researchers at the University of Massachusetts Amherst turns long-held conventional wisdom about a certain type of polymer on its head, greatly expanding understanding of how some of biochemistry’s fundamental forces work. The study, released recently in Nature Communications, opens the door for new biomedical research running the gamut from analyzing and identifying proteins and carbohydrates to drug delivery.
The work involves a kind of polymer made up of neutral ...
Electroactive biofiltration dynamic membrane: A new hope for wastewater treatment
2025-04-29
A recent study published in Engineering presents a novel approach to wastewater treatment and membrane fouling mitigation. The research, led by Zhiwei Wang from Tongji University, focuses on the development of an electroactive biofiltration dynamic membrane (EBDM).
The increasing scarcity of freshwater resources and the need for more efficient wastewater treatment have driven the search for innovative solutions. Anaerobic membrane bioreactors (AnMBRs) have shown promise, but membrane fouling remains a significant ...
Disparities in breast reconstruction persist after ACA, reports Plastic and Reconstructive Surgery
2025-04-29
April 29, 2025 — Despite steady increases in rates of immediate breast reconstruction (IBR) after mastectomy, racial disparities in IBR have persisted in the years since implementation of the Affordable Care Act (ACA), reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.
"Our study demonstrates that Hispanic women are more likely to undergo ...
Making magnetic biomaterials
2025-04-29
What if doctors could guide life-saving treatments through the body using only a magnet?
An interdisciplinary collaboration at the University of Pittsburgh’s Swanson School of Engineering is bringing that concept closer to reality with the development of silk iron microparticles (SIMPs)—tiny, magnetic, and biodegradable carriers designed to precisely deliver drugs and treatments to sites in the body like aneurysms or tumors.
Led by Pitt alumna Ande Marini (BioE PhD ‘25), now a postdoctoral scholar in cardiothoracic surgery at Stanford University, David Vorp, John A. Swanson Professor of bioengineering, and Justin Weinbaum, research ...
Synchrotron in a closet: Bringing powerful 3D X-ray microscopy to smaller labs
2025-04-29
Images
For the first time, researchers can study the microstructures inside metals, ceramics and rocks with X-rays in a standard laboratory without needing to travel to a particle accelerator, according to a study led by University of Michigan engineers.
The new technique makes 3D X-ray diffraction—known as 3DXRD—more readily accessible, potentially enabling quick analysis of samples and prototypes in academia and industry, as well as providing more opportunities for students.
3DXRD reconstructs 3D images using X-rays taken at multiple angles, similar to a CT scan. Instead of the imaging device rotating about ...
Multiscale fibrous reinforcements yield high-performance construction composite
2025-04-29
A recent study published in Engineering by Peizhao Zhou and Peng Feng from Tsinghua University introduces a novel construction material—flexible ultra-high performance reinforced cementitious composite (FHPRC). This material holds great potential for revolutionizing the construction industry with its excellent mechanical properties.
The research focuses on the concept of multiscale fibrous reinforcements in cementitious matrices. By carefully tailoring the types, sizes, and volume fractions of fibers, the researchers optimized the tensile ...
Using “shallow shadows” to uncover quantum properties
2025-04-29
It would be difficult to understand the inner workings of a complex machine without ever opening it up, but this is the challenge scientists face when exploring quantum systems. Traditional methods of looking into these systems often require immense resources, making them impractical for large-scale applications.
Researchers at UC San Diego, in collaboration with colleagues from IBM Quantum, Harvard and UC Berkeley, have developed a novel approach to this problem called “robust shallow shadows.” This technique allows scientists to extract essential information from quantum systems more efficiently and accurately, even in the presence of real-world noise and imperfections.
Imagine ...
China’s EV ultrafast charging stations: Challenges, solutions, and costs
2025-04-29
A new study published in Engineering delves into the future of ultrafast charging stations for electric vehicles (EVs) in China, exploring charging patterns, grid impacts, solutions, and upgrade costs. As the global EV market continues to expand rapidly, with China leading the way in EV adoption, understanding these aspects is crucial for sustainable development.
The research team, led by Yang Zhao, Xinyu Chen and Michael B. McElroy, analyzed real-world charging data from over 15,000 EVs at ...
AACR: New CAR T cell therapy benefits patients with advanced thyroid cancers
2025-04-29
Phase I trial demonstrates lasting responses and encouraging safety profile in two aggressive thyroid cancer subtypes, suggesting further progress for CAR T cell therapy in solid tumors
One patient experienced a complete response, and one patient had a partial response
This type of cancer has limited treatment options, and most patients have a poor prognosis of six months or less
AIC100 is a CAR T cell therapy that targets the ICAM-1 protein on tumor cells
ABSTRACT: CT206
CHICAGO, APRIL 29, 2025 ― A new chimeric antigen receptor (CAR) T cell therapy called AIC100, which targets the ICAM-1 protein, demonstrated encouraging responses and an acceptable safety ...
AcrOSS platform: Advancing safe UAS operations in critical areas
2025-04-29
In a recent development in the field of unmanned aircraft systems (UAS), a research team from the University of Salento in Italy has designed and tested a novel platform named AcrOSS. The details of this platform are published in Engineering, aiming to enhance the safety and efficiency of UAS operations in critical areas.
The widespread use of UAS in civil airspace, especially for beyond visual line-of-sight (BVLOS) operations, faces numerous challenges. The AcrOSS project, funded by the Italian Ministry for Research, focuses on developing ...
Quantum computing paves the way for low-carbon building operations
2025-04-29
A new study published in Engineering presents an innovative approach to building energy management that combines quantum computing with model predictive control (MPC), aiming to enhance energy efficiency and drive decarbonization in buildings.
Buildings are major energy consumers, contributing significantly to global energy use and greenhouse gas emissions. To address these issues, researchers Akshay Ajagekar and Fengqi You from Cornell University developed an adaptive quantum approximate optimization-based MPC strategy. This strategy is designed for buildings equipped with battery energy storage and renewable energy generation systems, such as photovoltaic (PV) panels.
The heart ...
HonorHealth Research Institute presents new findings in decades-long quest to conquer aggressive pancreatic cancer
2025-04-29
PHOENIX, Ariz. — April 30, 2025 — HonorHealth Research Institute’s new downtown Phoenix laboratory has produced its first study, centered on a promising new treatment for pancreatic cancer, one of the most aggressive and difficult to treat of all malignancies.
Study results were presented April 29 in Chicago at the annual meeting of the 58,000-member American Association for Cancer Research (AACR), the world’s largest professional organization of cancer investigators, caregivers and patient advocates.
Study findings indicate that a newly discovered drug, RMC-6236, also known as Daraxonrasib, is a powerful inhibitor of RAS (including KRAS, NRAS and HRAS). These ...
HonorHealth Research Institute is the first of 50 sites worldwide to treat a patient in a new clinical study aimed at melanoma
2025-04-29
SCOTTSDALE, Ariz. — April 29, 2025 — HonorHealth Research Institute recently treated the first patient in a 50-site international clinical trial that will test a new type of therapy aimed at difficult-to-treat melanoma, an aggressive type of skin cancer.
This new therapy targets PRAME, a peptide commonly found in melanoma tumors. The therapy uses the patient’s own manufactured and enhanced immune system T cells to create billions of new patient specific cells to attack melanoma, even after the cancer has spread to other parts of the body.
“We are excited about the potential of this new type of cellular therapy,” said Justin Moser, M.D., an associate ...
Surviving cancer, still suffering: Survey reveals gaps in follow‑up care
2025-04-29
Over 70% said mental health was not addressed during treatment
Less than a third had information about survivorship care
Northwestern oncologists are launching new survivorship clinic based on findings
Findings apply broadly to survivors of many cancers
CHICAGO --- More Americans are beating cancer than ever, yet many still grapple with treatment’s long shadow — especially on their mental health.
A new Northwestern Medicine study found most head-and-neck cancer survivors who underwent ...
A scientific method for flawless cacio e pepe
2025-04-29
WASHINGTON, April 29, 2025 – The beloved Italian pasta cacio e pepe is perhaps best known for two things: being delicious and being frustratingly difficult to cook. At first glance, it looks like a simple recipe, containing only three ingredients: pasta, pecorino romano cheese, and black pepper. But as anyone who has tried to make it will know, the cheese will often clump when added to the hot pasta water, turning what is supposed to be a smooth, creamy sauce into a stringy, sticky mess.
In Physics of Fluids, by AIP Publishing, researchers from the University of Barcelona, the Max Planck Institute for the Physics of Complex Systems, the University of Padova, and the Institute of Science ...
Uptake of and disparities in semaglutide and tirzepatide prescribing for obesity in the US
2025-04-29
About The Study: Semaglutide and tirzepatide prescriptions within Epic-affiliated health care systems increased slightly between 2021 and 2024, but their uptake remained limited, with only 3% of eligible patients having ever received a prescription during that period. Furthermore, there were disparities in prescribing of varying magnitude based on race and ethnicity, social vulnerability, and urbanicity, although the absolute differences were small compared with the overall underutilization.
Corresponding Author: To contact the corresponding author, Yuan Lu, ScD, email y.lu@yale.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2025.4735)
Editor’s ...
Bridging the AI gap in medicine: new framework targets family doctor education
2025-04-29
(Toronto, April 28, 2025) A team of Canadian researchers has developed a curriculum framework to help train future family physicians in the use of artificial intelligence (AI), addressing a critical gap in medical training as digital tools become more common in patient care. Published in JMIR Medical Education, the study, “Curriculum Framework for AI Training in Postgraduate Family Medicine Education (AIFM-ed): Mixed Methods Study,” introduces the AIFM-ed framework to guide the integration of AI into family medicine training programs.
As the health care system evolves, many medical professionals feel unprepared for the growing influence of AI in diagnostics, treatment, ...
Prenatal and perinatal factors of life’s essential 8 cardiovascular health trajectories
2025-04-29
About The Study: Pre-pregnancy overweight or obesity, smoking during pregnancy, and formula-feeding in the first 6 months of life were each associated with adverse cardiovascular health trajectories early in life in this cohort study. Future work should examine whether interventions that address these factors would be effective in optimizing cardiovascular health in children.
Corresponding Author: To contact the corresponding author, Izzuddin M. Aris, PhD, email izzuddin_aris@hphci.harvard.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.7774)
Editor’s ...
Maternal hypertension and adverse neurodevelopment in a cohort of preterm infants
2025-04-29
About The Study: In this preterm cohort study, maternal hypertensive disorders of pregnancy were independently associated with adverse cognitive and language development, with accentuated associations observed in preeclampsia-exposed preterm infants, emphasizing the clinical importance of recognizing hypertensive disorders of pregnancy as a risk, enabling targeted risk management strategies for closer monitoring and aggressive early intervention in affected populations.
Corresponding Author: To contact the corresponding author, Nehal A. Parikh, DO, MS, email nehal.parikh@cchmc.org.
To access the embargoed study: Visit our For The Media website at this ...
Menstrual cycle length changes following vaccination against influenza alone or with COVID-19
2025-04-29
About The Study: In this cohort study of individuals with regular menstrual cycles, influenza vaccine given alone or in combination with a COVID-19 vaccine was associated with a small but temporary change in menstrual cycle length. These findings may help clinicians confirm the utility of vaccination for patients with concerns about menstrual adverse effects of vaccination.
Corresponding Author: To contact the corresponding author, Alison Edelman, MD, MPH, email edelmana@ohsu.edu.
To access the embargoed study: ...
Study suggests dance and lullabies aren’t universal human behaviors
2025-04-29
Social singing and dance are often assumed to be hard-wired into the human condition; studies have supported the conclusion that these are common across cultures. But new research from a University of California, Davis, anthropologist challenges the idea that dance and lullabies are universal among humans. The study, published April 29 in Current Biology, draws on 43 years of research with the Northern Aché, an Indigenous population in Paraguay.
“Aside from church singing introduced by missionaries, Northern Aché adults sing alone and in a limited number of contexts,” said study author Manvir Singh, an assistant ...
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