Molecules in the spotlight: Snapshots reveal the eternal dance of particles
2025-08-07
FRANKFURT. Most of us find it difficult to grasp the quantum world: According to Heisenberg’s uncertainty principle, it’s like observing a dance without being able to see simultaneously exactly where someone is dancing and how fast they’re moving – you always must choose to focus on one. And yet, this quantum dance is far from chaotic; the dancers follow a strict choreography. In molecules, this strange behavior has another consequence: Even if a molecule should be completely frozen at absolute zero, it never truly comes to rest. The atoms it is made of perform a constant, never-ending quiet dance driven by so-called ...
What drives anaphylactic response in food allergies
2025-08-07
New research in mice reveals that food-induced anaphylaxis is driven by distinct immune pathways involving inflammatory lipids called leukotrienes. The findings, published across two separate studies, identify genetic and cellular factors that influence susceptibility to severe allergic reactions and point to the potential of the drug Zileuton to block this life-threatening response. Food allergies arise when the immune system mounts an exaggerated response to certain proteins found in foods. This reaction is typically driven by Immunoglobulin E (IgE) antibodies, which recognize dietary allergens and activates mast cells throughout the body. In severe ...
A thoughtful approach to governing emerging quantum technologies
2025-08-07
In a Policy Forum, Mateo Aboy and colleagues argue that, instead of turning immediately to rigid regulation to govern emerging quantum technologies, the community should apply a standards-based governance approach tailored to the early, technically focused stage of development. Quantum technologies are poised to revolutionize everything from computing to medicine, offering performance leaps that far surpass the limits of current systems. Yet, this promise comes with complex governance challenges, as these powerful tools ...
What makes the teeth of chitons iron hard?
2025-08-07
A group of marine mollusks called chitons produce extraordinarily tough teeth, which they use to scrape algae off rocks for food. Now, researchers report the protein RTMP1 (radular teeth matrix protein 1) appears to guide the precise formation of the iron-based mineral magnetite in the ultra-hard teeth of chitons. The findings mark the first known instance of an iron oxide-forming protein in a eukaryote, offering new insights into biomineralization and potential inspiration for novel materials design. Throughout the animal kingdom, many organisms ...
New antibody targeting approach, tested in mice, improves distribution and safety of Alzheimer’s immunotherapies
2025-08-07
A newly engineered antibody transport vehicle targeting the transferrin receptor enables enhanced delivery of anti-amyloid antibodies to the brains of mouse models of Alzheimer’s disease, researchers report. According to the study, the approach preserves key immune functions, such as microglial clearance of plaques, while offering a safer and more effective delivery strategy for anti–amyloid immunotherapies. Alzheimer’s disease (AD) is marked by the buildup of amyloid-β (Aβ) protein plaques in the brain. ...
UC Irvine scientist takes a lesson from ultrahard, wear-resistant mollusk teeth
2025-08-07
Irvine, Calif. — Researchers at the University of California, Irvine and Japan’s Okayama and Toho universities conducted a first-of-its-kind study to understand how chitons, mollusks that feed on algae growing on intertidal rocks, develop such hard, wear-resistant and magnetic teeth, and what they learned is inspiring new ways to produce advanced materials for a variety of applications. The results were published today in Science.
In its study, the team unveiled the process by which chiton-specific, iron-binding ...
ICFO researchers overcome long-standing bottleneck in single photon detection with twisted 2D materials
2025-08-07
The ability to detect single photons (the smallest energy packets constituting electromagnetic radiation) in the infrared range has become a pressing need across numerous fields, from medical imaging and astrophysics to emerging quantum technologies. In observational astronomy, for example, the light from distant celestial objects can be extremely faint and require exceptional sensitivity in the mid-infrared. Similarly, in free-space quantum communication—where single photons need to travel across vast distances—operating in ...
New scaffold technology helps combat traumatic brain injury by restoring copper balance
2025-08-07
Traumatic brain injury (TBI) remains one of the leading causes of disability worldwide. Recent research has developed a novel electrospun scaffold loaded with copper oxide (CuO@PG), which aims to restore copper homeostasis and modulate inflammation in TBI. The study shows that CuO@PG scaffolds significantly reduce neuronal pyroptosis (a form of programmed cell death), alleviate brain swelling, and improve motor and cognitive functions in animal models. These findings provide a promising therapeutic approach to mitigate the neurodegenerative effects ...
Bone metastases cultivate immature immune cells to resist immunotherapy
2025-08-07
AUGUST 7, 2025, NEW YORK – Many major cancers, including those of the lung, breast and prostate gland, spread to the bones as they progress. These bone metastases are often debilitating, even deadly. They are also notoriously resistant to all kinds of treatment, including immunotherapy.
Now a Ludwig Cancer Research study has identified in the microenvironment of bone tumors a key architect of that resistance. Researchers co-led by Taha Merghoub and Tao Shi of the Ludwig Collaborative Laboratory at Weill Cornell Medicine with colleagues at Nanjing ...
Liming can help enhance carbon capture in agricultural fields
2025-08-07
Adding crushed calcium carbonate — limestone — to agricultural fields can remove tons of carbon dioxide from the atmosphere each year while improving crop yields, a Yale-led study published in Nature Water found.
Greenhouse gases in the atmosphere hit a record high in 2024 reaching over 420 parts per million. The U.N. Intergovernmental Panel on Climate Change (IPCC) has identified carbon removal as one key tool in limiting warming to 1.5 C above pre-industrial levels to help mitigate climate change. To reach that target, 15 billion tons of carbon would have to be removed from the atmosphere each year.
“There ...
National study urges expanded vaccine screening in emergency departments
2025-08-07
RIVERSIDE, Calif. -- About 49% of people are unaware of one or more vaccines recommended for them. Further, 86% have not received one or more of these vaccines.
These are the findings of a University of California, Riverside-led study published today in Morbidity and Mortality Weekly Reports. The study is the first national comprehensive vaccine surveillance study conducted in emergency departments, or EDs — the only health care access point for millions of underserved Americans.
“Vaccination screening is one of the most fundamental public health interventions,” ...
Simple color-changing sensor quickly identifies poisonous gases
2025-08-07
Not all poisonous gases have a smell or a color. But a tiny grid of pastel- and candy-colored squares that effectively “sniffs” out hazardous chemicals in the air such as chlorosarin — a highly toxic nerve agent — could help detect them. Researchers report in ACS Sensors that the colorful patterns in their inexpensive and durable paper-based sensor array changed in the presence of poisonous gases, allowing for quick and accurate measurements within minutes.
Electronic noses, ...
Exosomes found to play a double role in tumor growth and immune response
2025-08-07
Tiny extracellular vesicles known as exosomes are emerging as key regulators of the tumor microenvironment (TME), influencing how cancer progresses, spreads, and responds to treatment. In a new review published in Med Research, researchers from Haikou Affiliated Hospital of Central South University Xiangya School of Medicine explore the dual nature of exosomes—highlighting their roles in both tumor promotion and immune modulation.
“Exosomes are not just passive carriers,” said Dr. Jiachong Wang, co-corresponding author of the paper. “They actively shape tumor biology by transferring RNAs, proteins, and ...
Announcing Gordian Biotechnology as Tier 5 Sponsor of ARDD 2025
2025-08-07
The University of Copenhagen is excited to announce Gordian Biotechnology as a Tier 5 Sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the biopharmaceutical industry that will transpire on August 25 - August 29, 2025 on-site at the Ceremonial Hall, University of Copenhagen, and online.
Gordian Biotechnology is a therapeutics company transforming how the industry discovers and develops treatments for age-related diseases. By integrating pooled screening in naturally occurring disease models, single-cell analysis, and in vivo gene therapy, ...
Disconnection between brain regions explains why some people don’t enjoy music
2025-08-07
Ten years ago, researchers discovered a small group of people who derive no pleasure from music despite having normal hearing and the ability to enjoy other experiences or stimuli. The condition, “specific musical anhedonia,” is caused by a disconnect between the brain’s auditory and reward networks. In a paper publishing August 7 in the Cell Press journal Trends in Cognitive Sciences, the team that discovered specific musical anhedonia describes the brain mechanisms behind the condition and discusses how understanding it could reveal other differences in how people experience ...
An interstellar mission to a black hole? Astrophysicist thinks it’s possible.
2025-08-07
It sounds like science fiction: a spacecraft, no heavier than a paperclip, propelled by a laser beam and hurtling through space at the speed of light toward a black hole, on a mission to probe the very fabric of space and time and test the laws of physics. But to astrophysicist and black hole expert Cosimo Bambi, the idea is not so far-fetched.
Reporting in the Cell Press journal iScience, Bambi outlines the blueprint for turning this interstellar voyage to a black hole into a reality. If successful, this century-long mission could return data from nearby ...
Earth’s natural CO2 vacuum cleaners
2025-08-07
Natural weathering processes are removing CO2 from the air in a wide range of environments across continents and ocean. Until recently these ‘CO2 vacuum cleaners’ were often studied separately, without properly examining their complex interactions. Now, an international team of earth scientists is proposing an integrated vision of the many factors that influence the removal of atmospheric CO2 from the highest mountain peaks to the deep ocean floor, including their various interactions. The so-called weathering continuum provides a much more complete picture on what controls and regulates the natural removal of CO2, which could ...
It's not all about size
2025-08-07
To the point
Power relationships between female and male gorillas: They are less strictly male-biased than previously thought. Females can overpower males despite the extreme male-biases in size and strength.
Revisiting traditional gender narratives: Females that overpower males have priority of access to food over these males, challenging the traditional narrative that females and males compete over different resources (females over food and males over females).
Over 50 years ago, the idea that males had universal ...
Cost-effectiveness of 2023-2024 COVID-19 vaccination in US adults
2025-08-07
About The Study: In this modeling study, economic favorability of COVID-19 vaccination varied by age. Cost-effectiveness results for individuals in the 2 older age groups were favorable and generally robust to changes in parameter inputs, while results for the younger age group were sensitive to parameter input changes. As the evidence base for COVID-19 vaccination and burden of illness evolves, it may be important to continue to update and revise the economic evaluation of vaccination. The Advisory Committee on Immunization Practices considered these results in its decision to recommend vaccination with the 2023 to 2024 COVID-19 mRNA ...
Demographics, lifestyle, comorbidities, prediabetes, and mortality
2025-08-07
About The Study: Stratified analyses in this study revealed that prediabetes was significantly associated with mortality only among younger adults (ages 20-54), highlighting the importance of age-specific interventions. Lifestyle behaviors, limited health care access, and life stage challenges may contribute to the increased mortality risk in younger adults. Early-onset health problems in this group may also reflect stronger genetic predispositions, leading to more rapid disease progression and more severe health outcomes. These findings underscore ...
Climate change: Perito Moreno Glacier retreat has recently accelerated substantially
2025-08-07
The Perito Moreno Glacier in Argentina — often described as one of the most stable glaciers in Patagonia — is retreating far more rapidly than previously thought, according to a paper in Communications Earth & Environment. The results show that, over the last few years, the glacier has retreated by as much as 800 metres in some areas, and that it may collapse and retreat by several kilometres in the near future.
The Perito Moreno Glacier is a 30-kilometre-long glacier in the Argentine Patagonia, fed by the Southern Patagonian Ice Field in the Andes and terminating in ...
Population history of the Southern Caucasus
2025-08-07
To the point
Stable genetic ancestry: Despite significant cultural changes, populations in the Southern Caucasus have maintained remarkably constant genetic ancestry for over 5,000 years.
Genetic contributions during the Bronze Age: Although local genetic continuity was predominant, there were partial genetic contributions from the Eurasian Steppe and from Anatolia during the Bronze Age.
Cultural influences: Practices such as cranial deformation were adopted primarily through cultural influences, rather than solely through migration.
New insights into the Southern Caucasus region: This research highlights the Southern Caucasus as ...
Biomarkers reveal risk of cardiovascular disease in type 2 diabetes
2025-08-07
Quick facts: Clinical research, 752 individuals with type 2 diabetes, quantitative study, DNA methylation as a way to identify epigenetic biomarkers in blood.
People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people. Therefore, biomarkers that help us understand which individuals are at risk of being affected are needed.
A research team led from Lund University in Sweden, followed 752 people who, when the study started, were newly diagnosed with type 2 diabetes. ...
UVA harnesses AI to improve brain cancer care
2025-08-07
University of Virginia School of Medicine scientists are tapping the power of artificial intelligence to enhance and accelerate treatment for glioblastoma, the deadliest brain cancer.
UVA researcher Bijoy Kundu, PhD, and colleagues are developing an AI imaging approach to distinguish between tumor progression and brain changes caused by tumor treatment. It now can take months to make that distinction, leaving doctors uncertain if the tumor is growing and stalling important care decisions.
Kundu’s AI approach is already outperforming ...
MIT imaging tech promises deepest looks yet into living brain tissue at single-cell resolution
2025-08-07
Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus. In a new study, a team of MIT scientists and engineers demonstrates a new microscope system capable of peering exceptionally deep into brain tissues to detect the molecular activity of individual cells by using sound.
“The major advance here is to enable us to image deeper at single-cell resolution,” ...
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