AURORA, Colo. (January 16, 2024) – Researchers from the University of Colorado Anschutz Medical Campus have found that a team intervention, provided by phone, leads to persistent improvements in depression, anxiety, and quality of life for people managing chronic illnesses. Additionally, researchers found that the improvement in quality of life results last months after intervention concludes. In a study, published today in JAMA, researchers observe the impact a telecare intervention program, called ADAPT, has on veterans suffering from poor quality of life as a result ...

An experiment outlined by a UCL (University College London)-led team of scientists from the UK and India could test whether relatively large masses have a quantum nature, resolving the question of whether quantum mechanical description works at a much larger scale than that of particles and atoms. Quantum theory is typically seen as describing nature at the tiniest scales and quantum effects have not been observed in a laboratory for objects more massive than about a quintillionth of a gram, or more precisely 10^(-20)g. The new experiment, described in a paper published in Physical Review Letters and involving researchers at UCL, the University of Southampton and ...

16 January 2024 – EMBO is pleased to announce that ten life scientists have been awarded EMBO Installation Grants, which support group leaders who will move to, or have recently moved to, countries participating in the scheme. The scientists’ inspiring research spans a wide range of biological processes: ageing, tumour biology, gut-brain axis communication, microbiota and gene editing tools are among the topics they are exploring. One installation grantee will establish a laboratory in the Czech Republic, one in Greece, two in Hungary, ...

The use of dual metal sulfides, specifically ZnS/CuS, shows marked improvement in electrochemical stability and performance when included in the design of flexible lithium-ion capacitors over the use of transition metal sulfides and carbon fiber materials.   Technology is becoming more and more integrated with daily life, especially wearable, flexible tech and smart devices. Transition metal sulfide (TMS) materials are popular among choices for anodes in developing flexible lithium-ion capacitors ...

Uncertainty estimation is critical to improving the reliability of deep neural networks. A research team led by Aydogan Ozcan at the University of California, Los Angeles, has introduced an uncertainty quantification method that uses cycle consistency to enhance the reliability of deep neural networks in solving inverse imaging problems. This research was published Dec. 21 in Intelligent Computing, a Science Partner Journal. Deep neural networks have been used to solve inverse imaging problems, such as image denoising, ...

The Aston Institute for Membrane Excellence (AIME) will be set up with a £10m grant from Research England AIME will be led by Professor Roslyn Bill from Biosciences and Professor Paul Topham from Chemical Engineering and Applied Chemistry The globally unique institute will use biomimetic polymer membranes for applications such as water purification and drug development Aston University will establish the Aston Institute for Membrane Excellence (AIME), a globally unique, cross-disciplinary institute to develop novel biomimetic membranes, after receiving a major grant of £10m from Research England. AIME will be led by Professor Roslyn Bill, from the School ...

In early 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a highly contagious and pathogenic virus, made its alarming debut and quickly spread worldwide, causing the novel coronavirus (COVID-19) pandemic that threatened human health and public safety. While the world was brought to a standstill, hospitals and health care systems entered unchartered territory and quickly adapted to the evolving health crisis to care for their community and keep potentially sick patients and health care workers from spreading the virus. The magnitude of response involved the reinforced universal masking of health care ...

Cambridge, Mass., Jan. 16, 2024 - A team of researchers from the ADA Forsyth Institute and University of North Carolina (UNC), Chapel Hill used single-cell transcriptomic analysis to successfully map dental pulp stem cells (DPSC) and periodontal ligament stem cells (PDLSC) and found remarkable differences between them. The study, which appeared in the Journal of Dental Research, provides the most detailed analysis of these stem cells to date, identifying the entire genome of the stem cells and their potential differentiation trajectories. “Dental pulp and periodontal ligament stem cells both have the potential to develop into any type of cell in the body,” ...

Neuroscientists from the University of Vienna and the Karolinska Institute in Stockholm have investigated whether playing violent video games leads to a reduction in human empathy. To do this, they had adult test subjects play a violent video game repeatedly over the course of an experiment lasting several weeks. Before and after, their empathic responses to the pain of another person were measured. It was found that the violent video game had no discernible effect on empathy and underlying brain activity. These results have now been published in the renowned journal eLife. Video games have become an integral part of the everyday life of many ...

WASHINGTON (Jan. 16, 2024) – Artificial intelligence (AI) has the potential to detect rheumatic heart disease (RHD) with the same accuracy as a cardiologist, according to new research demonstrating how sophisticated deep learning technology can be applied to this disease of inequity. The work could prevent hundreds of thousands of unnecessary deaths around the world annually.    Developed at Children’s National Hospital and detailed in the latest edition of the Journal of the American Heart Association, the new AI system combines the power of novel ultrasound probes with portable electronic ...

Knowing a patient’s weight is necessary for many weight-based medications such as thrombolytics, anticoagulants and numerous cardiovascular medications. Scaling drugs to a patient’s weight prevents adverse events from overtreatment and treatment failure due to underdosing. Inaccurate weight estimations may lead to inaccurate drug doses, which could cause patient harm.  However, in the emergency department (ED) during resuscitative care, measuring weight is often impossible. Moreover, little is known about the relative accuracy of different methods currently used to weigh patients during emergency care. For example, ...

TORONTO (16 January 2024) – As part of its pioneering approach to drug discovery, the Canadian nonprofit Conscience announced today that its first open science competition has resulted in the identification of seven promising molecules, or “hits,” that show potential for new, more effective drugs for familial Parkinson’s disease.  This first competition in Conscience’s CACHE (Critical Assessment of Computational Hit-Finding Experiments) Challenge series was funded by The ...

From inside an operating room in Barquisimeto, Venezuela, electrophysiologist Maria Milagros Arends, M.D., threads wires from a pacemaker through the veins and into the heart muscle of a patient.  This pacemaker, which regulates the heartbeat and can be lifesaving, was once in the body of another person. It has been recycled, or “reconditioned”— donated, tested, sterilized and shipped from the United States to the South American country for implantation.  “We have a waiting list of around 300 people who could potentially lose their lives in less than a month,” ...

CHAMPAIGN, Ill. — A new study links increased use of acetaminophen during pregnancy – particularly in the second trimester – to modest but noticeable increases in problems with attention and behavior in 2-, 3- and 4-year-olds. The study adds to a growing body of evidence linking the frequent use of acetaminophen in pregnancy to developmental problems in offspring. The findings are detailed in the journal Neurotoxicology and Teratology. The research is part of the Illinois Kids Development Study at the University of Illinois Urbana-Champaign, which explores how environmental ...

Monoclonal antibodies (mAbs) are laboratory-designed proteins that mimic the immune system's antibodies. To date, many therapeutic mAbs belonging to the immunoglobulin G (IgG) class of antibodies, have been approved for the treatment of cancer and autoimmune diseases. Cell lines such as the Chinese hamster ovary (CHO) cells are generally used to produce mAbs. Notably, the production and manufacture of mAbs are regulated by critical quality attributes (CQAs) to ensure their safety and efficacy in treatment. An important CQA for mAbs is the N-linked glycosylation present at a specific position (Asn297). N-linked glycans consist of N-acetylglucosamine (GlcNAc), mannose (Man), fucose ...

DALLAS, JANUARY 16, 2024 — A patient’s oral health can be an indicator of overall health and well-being. Research shows that chronic gum inflammation may be associated with other chronic diseases including coronary artery disease and diabetes.[1] In addition, certain bacteria that live in the mouth can travel through the bloodstream to other parts of the body, including the heart and lungs. Oral bacteria, including viridans group streptococcal (VGS), can cause infective endocarditis, an infection of the inner ...

PULLMAN, Wash. – While it is well known that cannabis can cause the munchies, researchers have now revealed a mechanism in the brain that promotes appetite in a set of animal studies at Washington State University. The discovery, detailed in the journal Scientific Reports, could pave the way for refined therapeutics to treat appetite disorders faced by cancer patients as well as anorexia and potentially obesity. After exposing mice to vaporized cannabis sativa, researchers used calcium imaging technology, which is similar to a brain MRI, to determine how their brain cells responded. They observed that cannabis activated a set of cells in the hypothalamus when the rodents anticipated ...

Osaka, Japan – Imagine stoplights and cars communicating with each other to optimize the flow of traffic. This isn’t science fiction – it’s the Internet of Things (IoT), i.e., objects that sense their surroundings and respond via the internet. As the global population rises and such technologies continue to develop, you might wonder – what will power this digital world of tomorrow? Wind, solar, yes. Something all around us might not immediately come to mind though – heat. Now, in a study recently published in Nature Communications, a multi-institutional research team including Osaka University has unveiled a ...

The ocean is the world’s largest habitat, yet much of its biodiversity is still unknown. A study published in Frontiers in Science marks a significant breakthrough, reporting the largest and most comprehensive database of marine microbes to date – matched with biological function, location, and habitat type.   “The KMAP Global Ocean Gene Catalog 1.0 is a leap toward understanding the ocean’s full diversity, containing more than 317 million gene groups from marine organisms around ...

Highlights: Research teams share findings and progress on projects aimed at harnessing digital solutions — including text messaging, smartphone apps, wearable devices and artificial intelligence — to improve health, reduce health care disparities, empower people to better manage their health and wellness and enhance patient/clinician connectivity in a special issue of the Journal of the American Heart Association. Topics in this issue include: the effectiveness of an “EyePhone” smartphone application to diagnose ...

In the US, approximately 37.9 million people, or 11.4% of the population, lived below the poverty line in 2022. It has been well demonstrated that poverty negatively affects physical and mental health. For example, people living in poverty run a greater risk of mental illness, heart disease, hypertension, and stroke, and have a higher mortality and lower life expectancy. The mechanisms by which poverty impacts on health outcomes are manifold: for example, people experiencing poverty have reduced access to healthy food, clean water, safe housing, education, and healthcare. Now, researchers have shown for the first time that the effects of poverty may combine in ...

A new study led by a University of Florida College of Public Health and Health Professions researcher finds that people with chronic inflammation living in poverty have more than double the risk of dying from heart disease and nearly triple the risk of dying from cancer within the next 15 years. The findings are based on data representing 95 million Americans ages 40 and over. While chronic inflammation and poverty are each known to increase mortality risk, when combined, the two factors appear ...

Despite major disruptions to health care systems during the COVID-19 pandemic, there was no significant increase in preventable conditions or deaths in children according to a large study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221726. To understand the effect of the pandemic on pediatric health care use and children's health, researchers looked at data on emergency visits, hospital admissions and deaths for children aged 0–17 years ...

Cannabis is not an effective treatment for opioid addiction, a new peer-reviewed study of thousands of people being treated for opioid use disorder suggests.    Experts, publishing their results today in The American Journal of Drug and Alcohol Abuse, have found that cannabis is having no significant effect on peoples’ use of opioids, taken outside of medical guidance.    The findings have substantial implications for U.S treatment programmes, some of which still require patients to abstain from cannabis before they qualify for potentially life-saving treatment. This is based on ...

Philadelphia, January 16, 2024 – Vaccination against SARS-CoV-2, the virus that causes COVID-19, reduces the risk of serious acute illness in children and adolescents. However, its role in protecting against persistent health problems in the months after COVID-19, or “long COVID,” was less clear. Now, researchers from 17 health systems in the U.S., in work led by investigators at the Children’s Hospital of Philadelphia (CHOP), have found that vaccination provides moderate protection against ...