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Ivermectin treatment in humans for reducing malaria transmission

2021-06-30
Malaria still kills millions. Researchers are excited by a new intervention: giving people a drug which kills mosquitoes that bite them. Incredibly, this is a reality, as the drug ivermectin, widely used for the control of parasite infections such as lymphatic filariasis and onchocerciasis, appears to do this. With some mosquitoes now resistant to the insecticides used in treated bed nets, this is a potentially important new control measure. LSTM's Dr Rebecca Thomas and Dr Joseph Okebe, together with Dr de Souza from the Noguchi Memorial Institute for Medical Research (NMIMR(link is external)), University of Ghana, first examined the experimental evidence that giving the drug to people kills the mosquitoes that bite them. All included studies showed large effects of ivermectin on ...

A future ocean that is too warm for corals might have half as many fish species

A future ocean that is too warm for corals might have half as many fish species
2021-06-30
Predicting the potential effects of coral loss on fish communities globally is a fundamental task, especially considering that reef fishes provide protein to millions of people. A new study led by the University of Helsinki predicts how fish diversity will respond to declines in coral diversity and shows that future coral loss might cause a more than 40% reduction in reef fish diversity globally. Corals increasingly bleach and often die when the water warms. What happens to fish if there are no alternative reefs to swim to? The few fish species that feed on corals will inevitably starve, but the rest might find alternative rocky habitat to persist. As yet, it has been hard to ...

Detailed simulation of air flow after sneezing to study the transmission of diseases

2021-06-30
By the beginning of April 2021, the number of people infected during the COVID-19 pandemic had risen to more than 130 million people of whom more than 2.8 million died. The SARS-CoV-2 virus responsible for COVID-19 is transmitted particularly by droplets or aerosols emitted when an infected person speaks, sneezes or coughs. This is how the viruses and other pathogens spread through the environment and transmit infectious diseases when they are inhaled by someone else. The capacity of these particles to remain suspended in the air and to spread in the environment depends largely on the size and nature of the air flow generated by the expiration of air. As with other airborne infectious diseases such as tuberculosis, common flu ...

Severe cannabis intoxication and rates of ingestion in children rise after legalization

2021-06-30
Significantly higher rates of child intensive care admissions for unintentional cannabis poisonings have been seen following legalization of the drug in Canada. Researchers from The Hospital for Sick Children (SickKids), based in Toronto, found a four-fold increase in unintentional poisonings in children under the age of 12 and a three-fold increase in intensive care admissions for severe cannabis poisoning in the first two years following cannabis legalization. However, the overall number of visits per month for cannabis intoxications to the SickKids Emergency Department (ED) remained consistent when comparing the pre- and post-legalization ...

NIST laser 'comb' systems now measure all primary greenhouse gases in the air

NIST laser comb systems now measure all primary greenhouse gases in the air
2021-06-30
Researchers at the National Institute of Standards and Technology (NIST) have upgraded their laser frequency-comb instrument to simultaneously measure three airborne greenhouse gases -- nitrous oxide, carbon dioxide and water vapor -- plus the major air pollutants ozone and carbon monoxide. Combined with an earlier version of the system that measures methane, NIST's dual comb technology can now sense all four primary greenhouse gases, which could help in understanding and monitoring emissions of these heat-trapping gases implicated in climate change. The newest comb system can also help assess urban air quality. These NIST instruments identify gas signatures by precisely measuring the amounts of light ...

Fecal records show Maya population affected by climate change

Fecal records show Maya population affected by climate change
2021-06-30
A McGill-led study has shown that the size of the Maya population in the lowland city of Itzan (in present-day Guatemala) varied over time in response to climate change. The findings, published recently in Quaternary Science Reviews, show that both droughts and very wet periods led to important population declines. These results are based on using a relatively new technique involving looking at stanols (organic molecules found in human and animal faecal matter) taken from the bottom of a nearby lake. Measurements of stanols were used to estimate changes in population size and to examine how they align with information about climate variability and changes in vegetation drawn from other biological and archaeological sources. By using the technique, the researchers were able ...

Buttoned up biomolecules

2021-06-30
Increasing our understanding of cellular processes requires information about the types of biomolecules involved, their locations, and their interactions. This requires the molecules to be labeled without affecting physiological processes (bioorthogonality). This works when the markers are very quickly and selectively coupled using small molecules and "click chemistry". In the journal Angewandte Chemie, a team of researchers has now introduced a novel type of click reaction that is also suitable for living cells and organisms. As an example, labeling biomolecules allows for the localization and characterization of tumors ...

COVID-19-mRNA vaccine induces good immune response against coronavirus variants

2021-06-30
A new Finnish study shows that 180 health care workers who had received two doses of the Pfizer and Biontech vaccine have very good antibody responses against the SARS-CoV-2 virus. The immune response was as strong against the alpha variant (formerly the UK variant) but was somewhat decreased against the beta variant (formerly the South Africa variant). Finnish researchers from the University of Turku and University of Helsinki together with Turku University Hospital, Helsinki University Hospital, and the Finnish Institute for Health and Welfare studied the immune response induced by the coronavirus vaccinations, which started in Finland in December. The researchers analysed vaccine responses ...

Eel products in the EU and the UK need better regulation

2021-06-30
Growing in popularity, unagi kabayaki - grilled freshwater eel in soy sauce - can be found on the menu of many Japanese restaurants, and is stocked by Asian shops and in specialist supermarkets. But new research tracing the DNA of eel fillets used for this dish has found that fraudulent food labelling is rife, with a third of the products violating EU regulations on the provision of food information. With certain species of eels now endangered, the researchers say that accurate labelling on these products is vital if the global eel trade is to be sustainable. The European eel is a critically ...

Floods may be nearly as important as droughts for future carbon accounting

2021-06-30
Plants play an essential role in curbing climate change, absorbing about one-third of the carbon dioxide emitted from human activities and storing it in soil so it doesn't become a heat-trapping gas. Extreme weather affects this ecosystem service, but when it comes to understanding carbon uptake, floods are studied far less than droughts - and they may be just as important, according to new research. In a global analysis of vegetation over more than three decades, Stanford University researchers found that photosynthesis - the process by which plants take up carbon dioxide from the atmosphere - was primarily influenced by floods and heavy rainfall nearly as often as droughts in many locations. The paper, published in Environmental Research Letters on June ...

Mixing it up: A low-cost way to make efficient, stable perovskite solar cells

Mixing it up: A low-cost way to make efficient, stable perovskite solar cells
2021-06-30
A key component of next-generation solar panels can be created without expensive, high-temperature fabrication methods, demonstrating a pathway to large scale, low-cost manufacturing for commercial applications. Nickel oxide (NiO) is used as an inexpensive hole-transport layer in perovskite solar cells because of its favourable optical properties and long-term stability. Making high-quality NiO films for solar cells usually requires an energy intensive and high-temperature treatment process called thermal annealing, which is not only costly, but also incompatible with plastic substrates, until now precluding the use of ...

Thinking in 3D improves mathematical skills

2021-06-30
Spatial reasoning ability in small children reflects how well they will perform in mathematics later. Researchers from the University of Basel recently came to this conclusion, making the case for better cultivation of spatial reasoning. Good math skills open career doors in the natural sciences as well as technical and engineering fields. However, a nationwide study on basic skills conducted in Switzerland in 2019 found that schoolchildren achieved only modest results in mathematics. But it seems possible to begin promoting math skills from a young ...

Thermal imaging offers early alert for chronic wound care

Thermal imaging offers early alert for chronic wound care
2021-06-30
New research shows thermal imaging techniques can predict whether a wound needs extra management, offering an early alert system to improve chronic wound care. It is estimated that 1-2% of the population will experience a chronic wound during their lifetime in developed countries - in the US, chronic wounds affect about 6.5 million patients with more than US$25 billion each year spent by the healthcare system on treating related complications.* The Australian study shows textural analysis of thermal images of venous leg ulcers (VLUs) can detect whether a wound needs extra management as early as week two for clients receiving treatment at home. The clinical study by RMIT University and Bolton Clarke, published in the Nature journal Scientific Reports, is the first to investigate ...

Extreme events: Ecosystems offer cost effective protection

2021-06-30
Decision-makers around the world are increasingly interested in using ecosystem solutions such as mangroves, coral reefs, sand dunes and forests on steep slopes to help buffer the impacts from hazard events and protect populations. But what evidence exists to show the efficacy of nature-based solutions over man-made protective measures to reduce the impacts of the increasing numbers of hazard events humanity faces due to climate change? An international, multi-disciplinary team of 28 researchers has examined nearly 20 years' worth of peer-reviewed studies on the impacts of ecosystem-based disaster ...

Study associates organic food intake in childhood with better cognitive development

2021-06-30
A study analysing the association between a wide variety of prenatal and childhood exposures and neuropsychological development in school-age children has found that organic food intake is associated with better scores on tests of fluid intelligence (ability to solve novel reasoning problems) and working memory (ability of the brain to retain new information while it is needed in the short term). The study, published in Environmental Pollution, was conceived and designed by researchers at the Barcelona Institute for Global Health (ISGlobal)--a centre supported by the "la Caixa" Foundation--and ...

Introducing the world's thinnest technology -- only two atoms thick

2021-06-30
A scientific breakthrough: Researchers from Tel Aviv University have engineered the world's tiniest technology, with a thickness of only two atoms. According to the researchers, the new technology proposes a way for storing electric information in the thinnest unit known to science, in one of the most stable and inert materials in nature. The allowed quantum-mechanical electron tunneling through the atomically thin film may boost the information reading process much beyond current technologies. The research was performed by scientists from the Raymond and Beverly Sackler School of Physics and Astronomy and Raymond and Beverly Sackler School of Chemistry. The group includes Maayan Vizner Stern, Yuval Waschitz, Dr. Wei Cao, Dr. Iftach Nevo, Prof. Eran Sela, Prof. Michael Urbakh, ...

5-minute workout lowers blood pressure as much as exercise, drugs

5-minute workout lowers blood pressure as much as exercise, drugs
2021-06-30
Working out just five minutes daily via a practice described as "strength training for your breathing muscles" lowers blood pressure and improves some measures of vascular health as well as, or even more than, aerobic exercise or medication, new CU Boulder research shows. The study, published June 29 in the Journal of the American Heart Association, provides the strongest evidence yet that the ultra-time-efficient maneuver known as High-Resistance Inspiratory Muscle Strength Training (IMST) could play a key role in helping aging adults fend off cardiovascular disease - the nation's leading killer. In the United States alone, 65% of adults over age 50 have ...

Employed individuals more likely to contract the flu, study shows

Employed individuals more likely to contract the flu, study shows
2021-06-30
A University of Arkansas researcher and international colleagues found that employed individuals, on average, are 35.3% more likely to be infected with the flu virus. The findings confirm a long-held assumption about one prevalent way illness spreads and could influence government policy on public health and several issues for private companies, from optimal design and management of physical work spaces to policy decisions about sick leave and remote work. To track influenza incidence, Dongya "Don" Koh, assistant professor of economics in the Sam M. Walton College of Business, and colleagues relied on nationally representative data from the Medical ...

College students experience significant grief reactions during global pandemic

2021-06-30
A new study shows that colleges students are experiencing significant grief reactions in response to the COVID-19 pandemic. The paper, "College Student Experiences of Grief and Loss Amid the COVID-19 Global Pandemic," was recently published in OMEGA - Journal of Death and Dying. "This study aimed to identify the most common non-death losses and grief reactions experienced by undergraduate and graduate college students amid the pandemic," said author Erica H. Sirrine, Ph.D., director of Social Work at St. Jude Children's Research Hospital. "What we found is that students ...

Researchers create better method to predict offshore wind power

Researchers create better method to predict offshore wind power
2021-06-30
New Brunswick, N.J. (June 28, 2021) - Rutgers researchers have developed a machine learning model using a physics-based simulator and real-world meteorological data to better predict offshore wind power. The findings appear in the journal Applied Energy. Offshore wind is rapidly maturing into a major source of renewable energy worldwide and is projected to grow by 13% in the next two decades and 15-fold by 2040 to become a $1 trillion industry, matching capital spending on gas- and coal-fired power generation. In the United States, for instance, New York and New Jersey recently awarded two offshore ...

Rattlesnakes may like climate change

Rattlesnakes may like climate change
2021-06-30
When it comes to climate change, not all organisms will lose out. A new Cal Poly study finds that rattlesnakes are likely to benefit from a warming climate. A combination of factors makes a warming climate beneficial to rattlesnakes that are found in almost every part of the continental United States but are especially common in the Southwest. Rattlers are experts at thermoregulation. Researchers found that, when given a choice, the snakes prefer a body temperature of 86-89 degrees Fahrenheit, a much warmer temperature than they generally experience in nature. The average ...

Reducing need for blood transfusion during heart surgery is focus of new practice guideline

2021-06-30
CHICAGO (June 30, 2021) -- Four leading medical specialty societies released a new clinical practice guideline today that includes recommendations for reducing blood loss during heart surgery and improving patient outcomes. The document, a multidisciplinary collaboration among The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, the American Society of ExtraCorporeal Technology, and the Society for the Advancement of Patient Blood Management, is available online in The Annals of Thoracic Surgery and two other journals. "As medicine evolves and we learn more, it always is important to review past ...

In-situ structural evolution of Zr-doped Na3V2(PO4)2F3 coated by N-doped carbon for SIB

In-situ structural evolution of Zr-doped Na<sub>3</sub>V<sub>2</sub>(PO<sub>4</sub>)<sub>2</sub>F<sub>3</sub> coated by N-doped carbon for SIB
2021-06-30
Na3V2(PO4)2F3(NVPF), a cathode material used in sodium-ion batteries (SIB), features ultrafast Na+ migration and high structural stability because of its three-dimensional open framework. However, the poor intrinsic electronic conductivity of NVPF often leads to high polarization, low Coulombic efficiency, and unsatisfactory rate performance, which hinder its commercial application. Recently, a group led by Prof. Shuangqiang Chen and Prof. Yong Wang from Shanghai University synthesized zirconium-doped NVPF nanoparticles coated with a nitrogen-doped ...

Breakthrough for tracking RNA with fluorescence

Breakthrough for tracking RNA with fluorescence
2021-06-30
Researchers at Chalmers University of Technology, Sweden, have succeeded in developing a method to label mRNA molecules, and thereby follow, in real time, their path through cells, using a microscope - without affecting their properties or subsequent activity. The breakthrough could be of great importance in facilitating the development of new RNA-based medicines. RNA-based therapeutics offer a range of new opportunities to prevent, treat and potentially cure diseases. But currently, the delivery of RNA therapeutics into the cell is inefficient. For new therapeutics to fulfil ...

Slowing down grape ripening can improve berry quality for winemaking

2021-06-30
Wine grapes are particularly finicky when it comes to their environment. For instance, heatwaves and droughts lead to earlier berry ripening and lackluster wine. And these types of episodes are expected to intensify as Earth's climate changes. Now, researchers reporting in ACS' Journal of Agricultural and Food Chemistry have tweaked growing conditions for Cabernet Sauvignon grapes to slow down their ripening, which increased the levels of compounds associated with wine's characteristic floral and fruity notes. As grapes ripen and change color from light green to deep red, sugars and aroma compounds accumulate in the berries. But, when they ripen quickly because of heat or water stress, the resulting fruits produce ...
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