Atrial fibrillation (AF) diagnosis was associated with a 45% increased risk of mild cognitive impairment (MCI) among a cohort of 4.3 million individuals in the UK, according to a new study published in JACC: Advances. These findings suggest that cardiovascular risk factors and multiple comorbidities could further the progression from MCI to dementia in this cohort. MCI is an early stage of cognitive function decline. In some cases it can be reversed, but it can indicate development of early dementia-associated disease. There has not been sufficient research on the development of MCI in AF patients and the subsequent development of dementia, so the authors of this study sought to ...

Flexible three-dimensional (3D) displays drive innovation in the next-generation display technology, as they allow for the creation of versatile and adaptable displays that can be easily manipulated and customized to fit various viewing scenarios.   Printing circularly polarized luminescence (CPL, generated by the intrinsic chirality of luminescent materials) materials on moving, deformable and free-form surfaces serves to fabricate large-scale and high-performance integral imaging 3D displays: CPL provides a helping hand using its unusual optical rotation characteristics to achieve considerable contrast ratio and wide viewing angle.   Scientists led by Professor ...

Zika virus infection in pregnant rhesus macaques slows fetal growth and affects how infants and mothers interact in the first month of life, according to a new study from researchers at the California National Primate Research Center at the University of California, Davis. The work, published Oct. 25 in Science Translational Medicine, has implications for both humans exposed to Zika virus and for other viruses that can cross the placenta, including SARS-CoV2, responsible for the COVID-19 pandemic. “Initially I thought this was a story about Zika, but as I looked at the results I think this is also a story about ...

Scientists have long known that chloroplasts help plants turn the sun’s energy into food, but a new study, led by plant biologists at the University of California, Davis, shows that they are also essential for plant immunity to viral and bacterial pathogens. Chloroplasts are generally spherical, but a small percentage of them change their shape and send out tube-like projections called “stromules.” First observed over a century ago, the biological function of stromules has remained ...

For four years, NASA’s InSight lander recorded tremors on Mars with its seismometer. Researchers at ETH Zurich collected and analysed the data transmitted to Earth to determine the planet’s internal structure. “Although the mission ended in December 2022, we’ve now discovered something very interesting,” says Amir Khan, a Senior Scientist in the Department of Earth Sciences at ETH Zurich. An analysis of recorded marsquakes, combined with computer simulations, paint ...

LAWRENCE — For the past 50 years, standardized tests have been the norm in American schools, a method proponents say determines which schools are not performing and helps hold educators accountable. Yet for the past 20 years, it has become clear that testing has failed to improve education or hold many accountable, according to a University of Kansas researcher whose new book details its history. “An Age of Accountability: How Standardized Testing Came to Dominate American Schools and Compromise Education” by John Rury, professor emeritus of educational leadership & policy studies at KU, tells the story of how testing became ...

October 25, 2023 On the Trail of the Silver King: Researchers at UMass Amherst Reveal Unprecedented Look at Tarpon Migration Culmination of more than five-years’ research, $1.1 million in grants and collaborations with anglers, industry and Bonefish & Tarpon Trust promises to reshape conservation efforts AMHERST, Mass. – New research led by the University of Massachusetts and published recently in Marine Biology unveils a first-of-its-kind dataset, gathered over five years, that gives the finest-grained ...

During the summer of 2022, the Indus River in Pakistan overflowed its banks and swept through the homes of between 30-40 million people. Eight million were permanently displaced, and at least 1,700 people died. Damages to crops, infrastructure, industry, and livelihoods were estimated at $30 billion. In response to this, Stanford researchers from the Natural Capital Project (NatCap) and the Carnegie Institution for Science collaborated on a new way to quickly calculate the approximate depths of ...

Rutgers researchers have used neuroimaging to demonstrate that cocaine addiction alters the brain’s system for evaluating how rewarding various outcomes associated with our decisions will feel. This dampens an error signal that guides learning and adaptive behavior. The observed changes likely propagate a mysterious aspect of some addictive behavior—the tendency to keep doing harmful things that sometimes have no immediate benefit. Those changes also make it harder for long-term users of cocaine to correctly estimate how much benefit they’ll derive from other available actions. Experts have long hypothesized that cocaine and other addictive ...

A new study by UC Davis Health endocrinology researchers has shown a high prevalence of thyroid cancer among transgender female veterans. It’s the first evidence of such a disparity in the transgender female population in the United States. The researchers presented their findings this month at the American Thyroid Association Annual Meeting. The study was prompted by what the doctors noticed while caring for patients. “As a group of physicians, we observed anecdotally through clinical observation that among 50 transgender women in our clinic, two were diagnosed with thyroid ...

FOR IMMEDIATE RELEASE In a mouse study designed to explore the impact of marijuana’s major psychoactive compound, THC, on teenage brains, Johns Hopkins Medicine researchers say they found changes to the structure of microglia, which are specialized brain immune cells, that may worsen a genetic predisposition to schizophrenia. The findings, published Oct. 25 in Nature Communications, add to growing evidence of risk to brain development in adolescents who smoke or eat marijuana products. “Recreational ...

A team of scientists has used multiple space and ground-based telescopes, including NASA’s James Webb Space Telescope, NASA’s Fermi Gamma-ray Space Telescope, and NASA’s Neil Gehrels Swift Observatory, to observe an exceptionally bright gamma-ray burst, GRB 230307A, and identify the neutron star merger that generated an explosion that created the burst. Webb also helped scientists detect the chemical element tellurium in the explosion’s aftermath. Other elements near tellurium on the periodic table – like iodine, which is needed ...

Inspired by the remarkable durability of ancient Roman construction materials in seawater, a University of Texas at Arlington civil engineering researcher is attempting to duplicate Roman concrete by developing 3D-printed materials to restore damaged or dying coral reefs. Warda Ashraf, associate professor in the Department of Civil Engineering, will lead a multidisciplinary team, funded by a $2 million National Science Foundation (NSF) grant, that aims to build 3D-printed artificial reefs. The team’s project is titled “Carbon Sequestration and Coastal Resilience Through 3D Printed Reefs” ...

– By Bonnie Powell Today’s world-changing scientific research is being conducted by collaborators at far-flung national laboratories who require high-speed, low-latency access to high performance computing facilities and specialized instruments. The Energy Sciences Network (ESnet) is proud to announce that it has supercharged the current and future bandwidth for four of the Department of Energy’s (DOE’s) national laboratories and user facilities, unleashing 400 Gigabit per second (400G) capability for Argonne National Laboratory, ...

HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson include positive results from a Phase I trial for patients with TP53-mutant acute myeloid leukemia, a novel machine learning ...

Humans have the ability to learn a new concept and then immediately use it to understand related uses of that concept—once children know how to “skip,” they understand what it means to “skip twice around the room” or “skip with your hands up.”  But are machines capable of this type of thinking? In the late 1980s, Jerry Fodor and Zenon Pylyshyn, philosophers and cognitive scientists, posited that artificial neural networks—the engines that drive artificial intelligence and machine learning— are not capable of making these connections, known as “compositional generalizations.” However, in the decades ...

SEATTLE – T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory – remembering the specific pathogens or the cancer signatures that originally trigger T cells.  Until now, understanding how a T cell forms into a specific role, for example a cell-killing (cytotoxic) T cell or memory T cell, has eluded us. In a paper that will be published online by Cell Reports on October 25, ISB researchers made the breakthrough ...

Researchers at Stockholm University have unveiled the hidden intricacies of how sperm go from passive bystanders to dynamic swimmers. This transformation is a pivotal step in the journey to fertilization, and it hinges on the activation of a unique ion transporter. Imagine sperm as tiny adventurers on a quest to reach the ultimate treasure, the egg. They don't have a map, but they make use of something even more extraordinary: chemo-attractants. These are chemical signals released by the egg that act as siren call, directing and activating the sperm. When these signals bind to receptors on the sperm's surface, it triggers a series of events, starting their movement towards ...

Researchers have developed a new way of improving diagnosis of bipolar disorder that uses a simple blood test to identify biomarkers associated with the condition. The researchers, from the University of Cambridge, used a combination of an online psychiatric assessment and a blood test to diagnose patients with bipolar disorder, many of whom had been misdiagnosed with major depressive disorder. The researchers say the blood test on its own could diagnose up to 30% of patients with bipolar disorder, but that it is even more effective when combined with a digital mental health assessment. Incorporating biomarker ...

Illegal hunting and trading of wildlife in China is becoming a significant threat to biodiversity and public health, according to a new paper by a team of researchers that includes two scholars from the School of Public and International Affairs. It is the first comprehensive assessment of this issue for China. The paper, "Assessing the illegal hunting of native wildlife in China," appears in Nature today. Its co-authors are Dan Liang, Xingli Giam, Sifan Hu, Liang Ma, and David S. Wilcove. Liang is an associate research scholar at SPIA's Center for Policy Research on Energy and the ...

About The Study: In this study with 9,479 participants, racial and ethnic survival disparities were identified in patients with early-stage breast cancer receiving standardized initial care, and potentially at-risk subgroups, for whom focused interventions may improve outcomes, were found.  Authors: Erica T. Warner, Sc.D., of Massachusetts General Hospital in Boston, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2023.39584 Editor’s Note: Please see the article for additional ...

About The Study: Terminating metformin treatment was associated with increased dementia incidence in this study of 12,000 early terminators and 29,000 routine users of metformin. This finding may have important implications for clinical treatment of adults with diabetes and provides additional evidence that metformin is associated with reduced dementia risk.  Authors: Sarah F. Ackley, Ph.D., of Boston University, Boston, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2023.39723) Editor’s Note: Please see the article ...

Researchers at the National Institute of Standards and Technology (NIST) and their colleagues have built a superconducting camera containing 400,000 pixels — 400 times more than any other device of its type. Superconducting cameras allow scientists to capture very weak light signals, whether from distant objects in space or parts of the human brain. Having more pixels could open up many new applications in science and biomedical research. The NIST camera is made up of grids of ultrathin electrical wires, cooled to near absolute zero, in which current moves with no resistance until a wire is struck by a photon. In these superconducting-nanowire cameras, the energy imparted by ...

A study led by UCLA researchers found that the children of parents who experienced adverse childhood experiences (ACEs)– such as abuse, neglect, violence in the home, or loss of a parent – are at increased risk of arrests and convictions by young adulthood. The authors report that their findings suggest that there is a crucial need for prevention of ACE exposure in the first place, as well as efforts to mitigate the impact of ACEs before they have downstream impacts on the next generation of children who are not yet born. The study appears in JAMA ...

Scientists have observed the creation of rare chemical elements in the second-brightest gamma-ray burst ever seen – casting new light on how heavy elements are made. Researchers examined the exceptionally bright gamma-ray burst GRB 230307A, which was caused by a neutron star merger. The explosion was observed using an array of ground and space-based telescopes, including NASA’s James Webb Space Telescope, Fermi Gamma-ray Space Telescope, and Neil Gehrels Swift Observatory. Publishing their findings today in Nature (25 Oct), ...