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The ‘Rapunzel’ virus: an evolutionary oddity

The ‘Rapunzel’ virus: an evolutionary oddity
2023-03-14
A recent study in the Journal of Biological Chemistry has revealed the secret behind an evolutionary marvel: a bacteriophage with an extremely long tail. This extraordinary tail is part of a bacteriophage that lives in inhospitable hot springs and preys on some of the toughest bacteria on the planet. Bacteriophages are a group of viruses that infect and replicate in bacteria and are the most common and diverse things on Earth. “Bacteriophages, or phages for short, are everywhere that bacteria are, including the dirt and water around you and in your own body’s microbial ecosystem as well,” said Emily Agnello, a graduate student at the University of ...

New treatment can improve cardiac pump function in patients with heart failure

2023-03-14
A clinical study by researchers at Karolinska Institutet and Karolinska University Hospital in Sweden shows that the hunger hormone ghrelin can increase the heart’s pump capacity in patients with heart failure. The results have been published in the European Heart Journal. Millions of people worldwide live with heart failure, a condition in which the pump function of the heart is reduced, such as after a myocardial infarction or angina. In heart failure, the heart muscle is weakened, leaving the heart unable to pump the amount of blood needed to provide the body with sufficient oxygen ...

Lasers and chemistry reveal how ancient pottery was made — and how an empire functioned

Lasers and chemistry reveal how ancient pottery was made — and how an empire functioned
2023-03-14
Peru’s first great empire, the Wari, stretched for more than a thousand miles over the Andes Mountains and along the coast from 600-1000 CE. The pottery they left behind gives archaeologists clues as to how the empire functioned. In a new study in the Journal of Archaeological Science: Reports, researchers showed that rather than using “official” Wari pottery imported from the capital, potters across the empire were creating their own ceramics, decorated to emulate the traditional Wari style. To figure it out, the scientists analyzed the pottery’s chemical make-up, with help from laser beams. “In this study, ...

Carnegie Mellon University researchers develop soft robot that shifts from land to sea with ease

Carnegie Mellon University researchers develop soft robot that shifts from land to sea with ease
2023-03-14
Most animals can quickly transition from walking to jumping to crawling to swimming if needed without reconfiguring or making major adjustments.  Most robots cannot. But researchers at Carnegie Mellon University have created soft robots that can seamlessly shift from walking to swimming, for example, or crawling to rolling. "We were inspired by nature to develop a robot that can perform different tasks and adapt to its environment without adding actuators or complexity," said Dinesh K. Patel, a post-doctoral fellow in the Morphing Matter Lab in the School of Computer Science's Human-Computer Interaction Institute. "Our bistable actuator ...

Future cargo ships could be powered by wind to fight climate change

Future cargo ships could be powered by wind to fight climate change
2023-03-14
Scientists to retrofit large shipping vessels with ultramodern sails in efforts to cut carbon emissions University of Southampton initiative will investigate how modern vessels perform on the ocean when fitted with the wing-sails Funding from Innovate UK to investigate the potential of the technology and decarbonise the UK’s maritime sector   SHIPS of the future could once again be powered by wind if a pioneering project which retrofits large vessels with ultramodern wing-sails proves successful in cutting carbon emissions. Scientists ...

Molecular biologist Shixin Liu receives Vilcek Prize for Creative Promise in Biomedical Science

Molecular biologist Shixin Liu receives Vilcek Prize for Creative Promise in Biomedical Science
2023-03-14
Shixin Liu receives the Vilcek Prize for Creative Promise in Biomedical Science for developing cutting-edge biophysical tools to directly visualize and understand the physiological function of nanometer-scale biomolecular machines such as those that carry out genome replication and gene transcription. The Vilcek Prize for Creative Promise is a $50,000 prize awarded annually by the Vilcek Foundation as part of its prizes program. Awarded annually since 2006, the Vilcek Foundation prizes recognize and celebrate immigrant contributions to scientific research and discovery, and to artistic and cultural advancement in the United States. In addition ...

Researchers develop enhanced genetic animal model of Down syndrome

Researchers develop enhanced genetic animal model of Down syndrome
2023-03-14
National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared to a previously studied Down syndrome mouse model. The results of this study, published in Biological Psychiatry, may help researchers develop more precise treatments to improve cognition in people with Down syndrome.  Scientists found that the new mouse model, known as Ts66Yah, had memory difficulties and behavior traits, but the symptoms were not as severe as seen with the ...

Climate change alters a human-raptor relationship

Climate change alters a human-raptor relationship
2023-03-14
Ithaca, NY— Bald Eagles and dairy farmers exist in a mutually beneficial relationship in parts of northwestern Washington State. According to a new study, this "win-win" relationship has been a more recent development, driven by the impact of climate change on eagles' traditional winter diet of salmon carcasses, as well as by increased eagle abundance following decades of conservation efforts. The research is published in the journal Ecosphere.   "The narrative ...

A mechanistic and probabilistic method for predicting wildfires

A mechanistic and probabilistic method for predicting wildfires
2023-03-14
Spanning long distances across variable terrains, electric power systems can spark wildfires in the event of dry weather and high winds. This may occur when conductor cables oscillate in such a way to become close to the surrounding vegetation. Data from the California Department of Forestry and Fire Protection shows that between 2016-2020, at least five of the top 20 most destructive California wildfires started from power systems. Paired with the extreme weather conditions and nearby vegetation, ...

This is what happens when your phone is spying on you

This is what happens when your phone is spying on you
2023-03-14
Smartphone spyware apps that allow people to spy on each other are not only hard to notice and detect, they also  will easily leak the sensitive personal information they collect,  says a team of computer scientists from New York and San Diego.  While publicly marketed as tools to monitor underage children and employees using their employer’s equipment, spyware apps are also frequently used  by abusers to covertly spy on a spouse or a partner. These apps  require little to no technical expertise from the abusers; offer detailed installation ...

New, non-invasive imaging tool maps uterine contractions during labor

2023-03-14
Researchers funded by the National Institutes of Health have developed a new imaging tool, called electromyometrial imaging (EMMI), to create real-time, three-dimensional images and maps of contractions during labor. The non-invasive imaging technique generates new types of images and metrics that can help quantify contraction patterns, providing foundational knowledge to improve labor management, particularly for preterm birth. The small study is supported in part by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) through its Human ...

Regional ECT, lithium, and clozapine use linked to lower suicide rates in male adolescents

2023-03-14
A new study from Karolinska Institutet suggests that electroconvulsive therapy (ECT), lithium, and clozapine may reduce suicide rates in adolescent men with severe mental illness, consistent with previous findings in adults. The study, published in Nature Communications, compared treatment and suicide rates across different regions in Sweden. Annually, there are 800,000 suicide deaths worldwide. Suicide is the leading cause of death among teenagers and young adults, with up to 90 percent of those affected having a serious psychiatric illness ...

Imaging tech produces real-time 3D maps of uterine contractions during labor

Imaging tech produces real-time 3D maps of uterine contractions during labor
2023-03-14
Researchers at Washington University School of Medicine in St. Louis have developed new imaging technology that can produce 3D maps showing the magnitude and distribution of uterine contractions in real time and across the entire surface of the uterus during labor. Building on imaging methods long used on the heart, this technology can image uterine contractions noninvasively and in much greater detail than currently available tools, which only indicate the presence or absence of a contraction. The ...

Tech could help BC farmers reach customers, mitigate climate change impacts

2023-03-14
Technology exists that the BC government could leverage to help small farmers connect directly with consumers and also mitigate climate change impacts, say new findings from UBC Okanagan. Dr. John Janmaat and Dr. Joanne Taylor co-authored new research that examines how farmers in the Okanagan and Cariboo regions of BC are adapting compared to farmers in China’s Shaanxi province. One of the key differences was how Chinese farmers used technology and social media, an option that’s not as widely used in ...

High winds can worsen pathogen spread at outdoor chicken farms

High winds can worsen pathogen spread at outdoor chicken farms
2023-03-14
PULLMAN, Wash. – Farmers who keep their chickens outdoors may want to watch the weather. A study of chicken farms in the West found that high winds increased the prevalence of Campylobacter in outdoor flocks, a bacterial pathogen in poultry that is the largest single cause of foodborne illness in the U.S. Researchers found that about 26% of individual chickens had the pathogen at the “open environment” farms in the study, which included organic and free-range chicken farms. High winds the week prior to sampling and the farms’ location in more intensive agricultural settings were linked to a greater prevalence of ...

Environmental justice scholar Joan Martinez-Alier named 2023 Holberg Prize Laureate

Environmental justice scholar Joan Martinez-Alier named 2023 Holberg Prize Laureate
2023-03-14
Joan Martinez-Alier is Professor Emeritus at the Institute of Environmental Science and Technology, at the Universitat Autònoma de Barcelona (ICTA-UAB). He will receive the award of NOK 6,000,000 (approx. EUR 550,000) during an 8 June ceremony at the University of Bergen, Norway. Martinez-Alier receives the Holberg Prize for his ground-breaking research in ecological economics, political ecology and environmental justice. He is known for criticizing established economic theory and traditional approaches to economic growth. Martinez-Alier is also a major figure and leading public intellectual in the burgeoning movement for ’degrowth’. Degrowth ...

Glucose-dependent insulinotropic polypeptide prevents diet-induced obesity in mice

Glucose-dependent insulinotropic polypeptide prevents diet-induced obesity in mice
2023-03-14
The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive. Recently, researchers demonstrated acute feeding inhibition and lowered body weight in mice with diet-induced obesity treated with GIPFA-085, a long-acting GIPRA. Their findings provide a scientific basis for GIP therapy for diabetes and obesity. Obesity, ...

Protecting messengers of the gods: Conservation of Nara Park deer has resulted in unique genetic lineage

Protecting messengers of the gods: Conservation of Nara Park deer has resulted in unique genetic lineage
2023-03-14
The existing wildlife of a region is heavily shaped over generations by environmental factors and human activity. Activities like urbanization and hunting are known to reduce wildlife populations. However, some cultural or religious practices have, on occasion, preserved local animal populations. For instance, the forests around religious shrines in Japan have historically forbidden hunting and, as a consequence, provide refuge for certain animal species. A well-known example of this is the Japanese sika deer (Cervus nippon), which has historically been considered a holy creature.   A revered ...

British public back ban on selling junk foods at checkouts study shows

British public back ban on selling junk foods at checkouts study shows
2023-03-14
Shoppers join food industry and health experts in backing UK plans to ban high fat, salt and sugar products from checkouts, store entrances and aisle ends Consumers and retailers were asked about the impact of new government legislation aiming to restrict how unhealthy food is sold Scientists behind investigation say ban can curb impulse buys that cause obesity – but warn of loopholes and limited resources that could undermine health benefits   A ban on selling junk foods from store entrances, aisle ends and checkouts should continue after a new study found the plans were largely backed by the British public and food industry. Legislation ...

EPND launches its Cohort Catalogue, facilitating discovery of over 60 neurodegeneration research cohorts from 17 countries across Europe

EPND launches its Cohort Catalogue, facilitating discovery of over 60 neurodegeneration research cohorts from 17 countries across Europe
2023-03-14
On 14 March, the European Platform for Neurodegenerative Diseases (EPND) launched its Cohort Catalogue. Featuring an extensive list of international cohorts across the neurodegenerative disease spectrum, the Cohort Catalogue is a central, open, accessible repository for researchers to discover ongoing studies and search metadata by disease area, biosample availability, imaging and cognitive data, and more.  The EPND consortium brings together experts in neurodegeneration research, data science, diagnosis and treatment from 29 public and private organisations. Funded by ...

Help Harry Help Others and Aston University join forces to develop pioneering treatment of brain tumors in children

Help Harry Help Others and Aston University join forces to develop pioneering treatment of brain tumors in children
2023-03-14
Birmingham based charity, Help Harry Help Others and Aston University researchers, are working together to develop a pioneering pre-surgical diagnostic tool, which could see the eventual outcome of children with brain tumours drastically improve. Help Harry Help Others, which became a registered charity in September 2012 and marked its 10th anniversary last year, was founded by Georgie Moseley, following the passing of her son Harry. Despite fighting an inoperable brain tumour, Harry raised over £750,000 for cancer research in the last two years of his life, before he passed away ...

Machine learning helps researchers separate compostable from conventional plastic waste with ‘very high’ accuracy

2023-03-14
Disposable plastics are everywhere: Food containers, coffee cups, plastic bags. Some of these plastics, called compostable plastics, can be engineered to biodegrade under controlled conditions. However, they often look identical to conventional plastics, get recycled incorrectly and, as a result, contaminate plastic waste streams and reduce recycling efficiency. Similarly, recyclable plastics are often mistaken for compostable ones, resulting in polluted compost. Researchers at University College London (UCL) have published a paper in Frontiers ...

Observations open door to improved luminous efficiency of organic LEDs

Observations open door to improved luminous efficiency of organic LEDs
2023-03-14
Electroluminescence is the production of light with an electrical current, without relying on heat or chemical reactions. This makes electroluminescent lights reliable and highly efficient: they are used as backlights in digital watches and in the displays of Apollo space shuttle guidance computers. Like OLEDs, light-emitting electrochemical cells (LECs)—which emit light through electroluminescence—have undergone many technological advancements. Close examination of the processes that lead to luminescence is essential ...

Rice labs seek RNA programming for ‘smart’ antibiotics

Rice labs seek RNA programming for ‘smart’ antibiotics
2023-03-14
HOUSTON – (March 13, 2023) – Synthetic biologists at Rice University are embarking on a three-year project to create “genetically encoded antibiotics,” strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria. “Most bacteria pose no danger to human health,” said James Chappell, an assistant professor of biosciences and bioengineering at Rice. “The question for us as synthetic biologists is, ‘Can we create genetic programs that move through microbial communities and precisely remove only the bad actors from those communities?’” Thanks ...

Attracting stem cells and facilitating bone regeneration by adhesive protein

Attracting stem cells and facilitating bone regeneration by adhesive protein
2023-03-14
One of the key factors of success in a dental implant is the condition of the periodontium around the implant. A higher long-term success rate of dental implants requires sufficient and healthy alveolar bone. In those cases where lack of alveolar bone renders setting an implant difficult, the bone should be regenerated sufficiently to receive the implant, whether before or during the implant surgery. Development of osteogenic barrier coating material for implants by a Korean research team is expected to improve the success rate of alveolar bone grafting.   Three research teams led by Professor Hyung Joon Cha of the Chemical Engineering ...
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