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DOE renews CABBI for five more years

DOE renews CABBI for five more years
2023-03-17
The U.S. Department of Energy (DOE) has committed another round of funding to the University of Illinois Urbana-Champaign to lead the second phase of its Bioenergy Research Center — one of four large-scale DOE-funded research centers focused on innovation in biofuels, bioproducts, and a clean energy future for the country. Earlier today the DOE announced a five-year extension of funding for the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), to a total of $237.9 million for the period from 2017 to 2027. CABBI ...

Study attempts to identify bacterial indicator species of obesity and metabolic syndrome in adult and pediatric patients

2023-03-17
Alexandria, VA – A study aiming to identify biomarker species associated with obesity and metabolic syndrome (MetS) was presented at the 52nd Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 47th Annual Meeting of the CADR. The AADOCR/CADR Annual Meeting & Exhibition took place at the Oregon Convention Center in Portland on March 15-18, 2023. The study, led by Tanveer Vasdev of the University of Iowa, analyzed 208 saliva and subgingival samples from periodontally, healthy, frequency-matched patients belonging to adult and pediatric obesity and MetS. Bacterial ...

Aging | Senescence-associated exosomes transfer fibrosis to neighboring cells

Aging | Senescence-associated exosomes transfer fibrosis to neighboring cells
2023-03-17
“This shows that SA-EXOs can serve as potent SASP mediators that activate invasive characteristics in neighboring cells.” BUFFALO, NY- March 17, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, “Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells.” Radiation-induced fibrosis is a common side effect of radiotherapy, which is the most common ...

Sutharshan named ORNL deputy for operations

Sutharshan named ORNL deputy for operations
2023-03-17
Balendra Sutharshan has been named chief operating officer for Oak Ridge National Laboratory. He will begin serving as ORNL’s deputy for operations and as executive vice president, operations, for UT-Battelle LLC effective April 1. He will succeed Alan Icenhour, who is retiring this spring after serving in the role since 2021. UT-Battelle operates ORNL for the Department of Energy. Sutharshan joined ORNL in February 2021 as the associate laboratory director for the Isotope Science and Engineering Directorate. Under his leadership, ISED has achieved remarkable growth in isotope research and development, as well as production ...

Carnegie Mellon to lead NASA Space Technology Research Institute

Carnegie Mellon to lead NASA Space Technology Research Institute
2023-03-17
In space travel, custom parts for vehicles such as rockets and satellites are often needed quickly to accommodate changes in design, as well as for repair and functionality purposes. Additive manufacturing is an ideal technology to meet these needs, as components can be made through a relatively short cycle of design, build, and test. However, this cycle must be continually refined in order to ensure the quality and reliability of the 3D printed parts. A new NASA Space Technology Research Institute (STRI) led by Carnegie Mellon University seeks to shorten the cycle required to design, manufacture, and test parts that can withstand ...

DOE announces $590 million to increase bioenergy research

2023-03-17
WASHINGTON, D.C. — The U.S. Department of Energy (DOE) today announced $590 million to renew its four existing Bioenergy Research Centers (BRCs). This funding will help support the Department’s research into the next generation of sustainable, cost-effective bioproducts and bioenergy from domestic biomass resources, which is critical to reducing harmful greenhouse gas emissions, ensuring future energy security, and creating new economic opportunities in rural areas. Since their inception, the BRCs have made groundbreaking scientific contributions to and advancements ...

The University of Queensland-Ochsner Health Medical Program celebrates high residency match; see Ochsner’s full Match Day results for 2023

2023-03-17
NEW ORLEANS, La. – The University of Queensland-Ochsner Health (UQ-Ochsner) Doctor of Medicine (MD) program and Ochsner Graduate Medical Education on March 17 celebrated Match Day 2023 – a rite of passage in which applicants from around the globe learn who has been selected for which U.S. residency program to start the next chapter of medical training. This year, 78 medical graduates from UQ-Ochsner’s Class of 2022 entered the match and received a 96% match rate through the National Residency Match Program (NRMP) – one that exceeded the national match rate for U.S. medical schools. Leonardo ...

On World Sleep Day, new research reveals the socioeconomic impact of insomnia on global populations

2023-03-17
Insomnia is the most common sleep disorder and exacts a significant toll on an individual’s mental and physical health, quality of life and productivity. But the consequences of insomnia go well beyond the individual, with cascading effects on families, employers and global economies.  Amid growing evidence that the condition is increasing globally, new research from RAND Europe, funded by Idorsia Pharmaceuticals Ltd, Switzerland and published on World Sleep Day 2023, reveals the societal ...

Researcher-community partnership uses collaborative process to yield novel insights

Researcher-community partnership uses collaborative process to yield novel insights
2023-03-17
RIVERSIDE, Calif. -- Until recently, psychologist Kalina Michalska had never used community-based participatory research, or CBPR, in her work, but now she can’t imagine not using it. CBPR, which dates to the early 1930s, is an intensive research approach that involves partnerships between researchers and community members throughout the research process, giving communities a voice in how the research proceeds and allowing them to make use of the findings more effectually. The study led by Michalska, an ...

Boosting survival of a beneficial bacterium in the human gut

2023-03-17
New Haven, Conn. — The microbes that inhabit the gut are critical for human health, and understanding the factors that encourage the growth of beneficial bacterial species — known as “good” bacteria — in the gut may enable medical interventions that promote gut and overall human health. In a new study, Yale researchers have uncovered a novel mechanism by which these bacteria colonize the gut. Specifically, the Yale team discovered that one of the most abundant beneficial species found in the human gut showed an increase in colonization potential when experiencing carbon limitation — a finding that could yield novel clinical ...

International Society for Autism Research (INSAR) 22nd Annual Meeting to be held in Stockholm, Sweden May 3- 6, 2023

2023-03-17
The International Society for Autism Research (INSAR) will hold its 2023 Annual Meeting – the organization’s 22nd – from Wednesday, May 3 through Saturday, May 6, 2023, bringing together a global, multidisciplinary group of hundreds of autism researchers, clinicians, advocates, self-advocates, and students to exchange the latest scientific learnings and discoveries that are advancing the expanding understanding of autism and its complexities. This year’s meeting will be held in-person in Stockholm, Sweden at Stockholmsmässan, the largest exhibition facility in the Nordic region. The INSAR ...

Genomic study of ancient humans sheds light on human evolution on the Tibetan Plateau

Genomic study of ancient humans sheds light on human evolution on the Tibetan Plateau
2023-03-17
The Tibetan Plateau, the highest and largest plateau above sea level, is one of the harshest environments settled by humans. It has a cold and arid environment and its elevation often surpasses 4000 meters above sea level (masl). The plateau covers a wide expanse of Asia—approximately 2.5 million square kilometers—and is home to over 7 million people, primarily belonging to the Tibetan and Sherpa ethnic groups. However, our understanding of their origins and history on the plateau is patchy. Despite a rich archaeological context spanning the plateau, ...

Key role identified for nervous system in severe allergic shock

2023-03-17
DURHAM, N.C. – A key feature of the severe allergic reaction known as anaphylaxis is an abrupt drop in blood pressure and body temperature, causing people to faint and, if untreated, potentially die.   That response has long been attributed to a sudden dilation and leakage of blood vessels. But in a study using mice, Duke Health researchers have found that this response, especially body temperature drop, requires an additional mechanism – the nervous system.   Appearing online March 17 in the journal Science Immunology, the study could ...

Researchers develop biodegradable, biorecyclable glass

Researchers develop biodegradable, biorecyclable glass
2023-03-17
Everyone is familiar with glass—from putting on eyeglasses, pushing open the window, standing in front of a mirror, to holding a water glass. Glass is ubiquitous in nature and essential to human life. But the widespread use of persistent, non-biodegradable glass that cannot be naturally eliminated causes long-term environmental hazards and social burdens. To solve this problem, a research group led by Prof. YAN Xuehai from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences has developed a family of eco-friendly glass of biological origin fabricated from biologically derived amino acids or peptides. The ...

Qubits put new spin on magnetism: Boosting applications of quantum computers

Qubits put new spin on magnetism: Boosting applications of quantum computers
2023-03-17
LOS ALAMOS, N.M., March 17, 2023 — Research using a quantum computer as the physical platform for quantum experiments has found a way to design and characterize  tailor-made magnetic objects using quantum bits, or qubits. That opens up a new approach to develop new materials and robust quantum computing. “With the help of a quantum annealer, we demonstrated a new way to pattern magnetic states,” said Alejandro Lopez-Bezanilla, a virtual experimentalist in the Theoretical Division at Los Alamos National Laboratory. ...

New combination of drugs works together to reduce lung tumors in mice

New combination of drugs works together to reduce lung tumors in mice
2023-03-17
LA JOLLA—(March 17, 2023) Cancer treatments have long been moving toward personalization—finding the right drugs that work for a patient’s unique tumor, based on specific genetic and molecular patterns. Many of these targeted therapies are highly effective, but aren’t available for all cancers, including non-small cell lung cancers (NSCLCs) that have an LKB1 genetic mutation. A new study led by Salk Institute Professor Reuben Shaw and former postdoctoral fellow Lillian Eichner, now an assistant professor ...

Biomarkers show promise for identifying early risk of pancreatic cancer

2023-03-17
DURHAM, N.C. – A research team at Duke Health has identified a set of biomarkers that could help distinguish whether cysts on the pancreas are likely to develop into cancer or remain benign.   Appearing online March 17 in the journal Science Advances, the finding marks an important first step toward a clinical approach for classifying lesions on the pancreas that are at highest risk of becoming cancerous, potentially enabling their removal before they begin to spread.   If successful, the biomarker-based approach could address the biggest impediment to decreasing the ...

Discovery of root anatomy gene may lead to breeding more resilient corn crops

Discovery of root anatomy gene may lead to breeding more resilient corn crops
2023-03-17
UNIVERSITY PARK, Pa. — A new discovery, reported in a global study that encompassed more than a decade of research, could lead to the breeding of corn crops that can withstand drought and low-nitrogen soil conditions and ultimately ease global food insecurity, according to a Penn State-led team of international researchers.  In findings published March 16 in the Proceedings of the National Academy of Science, the researchers identified a gene encoding a transcription factor – a protein useful for converting DNA into RNA – that triggers a genetic sequence responsible for the development of an important trait enabling corn roots ...

New study shows social media content opens new frontiers for sustainability science researchers

2023-03-17
With more than half of the world’s population active on social media networks, user-generated data has proved to be fertile ground for social scientists who study attitudes about the environment and sustainability.   But several challenges threaten the success of what's known as social media data science. The primary concern, according to a new study from an international research team, is limited access to data resulting from restrictive terms of service, shutdown of platforms, data manipulation, censorship and regulations.   The study, published online March ...

East and West Germans show preference for different government systems 30 years on

2023-03-17
Even after 27 years of reunification, East Germans are still more likely to be pro-state support than their Western counterparts, a new study published in the De Gruyter journal German Economic Review finds. Of the sample studied, 48% of respondents from the East said it was the government’s duty to support the family compared to 35% from the West.  The study led by Prof. Nicola Fuchs-Schündeln of Goethe University Frankfurt, Germany builds on her earlier work which evaluated results from the German Socio-Economic Panel, a regular survey of around 15,000 households. The survey has been running in the federal ...

NASA announces future launch for USU-led space weather mission

NASA announces future launch for USU-led space weather mission
2023-03-17
NORTH LOGAN, UTAH - NASA has announced that the launch of the Utah State University Space Dynamics Laboratory and College of Science-led Atmospheric Waves Experiment, or AWE, is scheduled for December 2023. The NASA-funded instrument will launch from Cape Canaveral Space Force Station to the International Space Station. AWE Principal Investigator Michael Taylor from USU’s College of Science leads a team of scientists that will provide new details about how the weather on Earth interacts with, and affects, space weather. To do that, the AWE instrument, measuring about 54 centimeters by 1 meter and weighing less than 57 kilograms, will peer into Earth’s ...

Quantum sensing in outer space: New NASA-funded research will build next-gen tech to better measure climate

Quantum sensing in outer space: New NASA-funded research will build next-gen tech to better measure climate
2023-03-17
Texas Engineers are leading a multi-university research team that will build technology and tools to improve measurement of important climate factors by observing atoms in outer space.  They will focus on the concept of quantum sensing, which use quantum physics principles to potentially collect more precise data and enable unprecedented science measurements. These sensors could help satellites in orbit collect data about how atoms react to small changes in their environment, and using that to infer the ...

Scientists identify the mechanisms leading to resistance to lung cancer treatment with Sotorasib, the first KRAS inhibitor

Scientists identify the mechanisms leading to resistance to lung cancer treatment with Sotorasib, the first KRAS inhibitor
2023-03-17
A collaborative study carried out by the groups of Matthias Drosten, principal investigator at the Cancer Research Center (CSIC- University of Salamanca), and Mariano Barbacid, head of the Experimental Oncology group at the CNIO, reveals the mechanisms responsible for the development of tumor resistance to Sotorasib, the first approved inhibitor against the KRAS oncogene. The study, recently published in the Journal of Clinical Investigation, shows that lung tumor cells can rapidly adapt to this drug by increasing the number of copies of the mutated KRAS gene targeted by the treatment and by increased expression of xenobiotic pathways that limit ...

Fossil site is ‘Rosetta Stone’ for understanding early life

Fossil site is ‘Rosetta Stone’ for understanding early life
2023-03-17
Fossil site is ‘Rosetta Stone’ for understanding early life Leading edge technology has uncovered secrets about a world-renowned fossil hoard that could offer vital clues about early life on earth. Researchers who analysed the 400 million-year-old-cache, found in rural north-east Scotland, say their findings reveal better preservation of the fossils at a molecular level than was previously anticipated. Fresh scrutiny of the exquisitely preserved treasure trove from Aberdeenshire has enabled scientists to identify the chemical fingerprints of the various organisms within ...

3D-printed revolving devices can sense how they are moving

3D-printed revolving devices can sense how they are moving
2023-03-17
Integrating sensors into rotational mechanisms could make it possible for engineers to build smart hinges that know when a door has been opened, or gears inside a motor that tell a mechanic how fast they are rotating. MIT engineers have now developed a way to easily integrate sensors into these types of mechanisms, with 3D printing. Even though advances in 3D printing enable rapid fabrication of rotational mechanisms, integrating sensors into the designs is still notoriously difficult. Due to the complexity of the rotating parts, sensors are typically embedded manually, after the device has already ...
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