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Galactic gamma ray bursts predicted last year show up right on schedule

Galactic gamma ray bursts predicted last year show up right on schedule
2021-07-13
Magnetars are bizarre objects -- massive, spinning neutron stars with magnetic fields among the most powerful known, capable of shooting off brief bursts of radio waves so bright they're visible across the universe. A team of astrophysicists has now found another peculiarity of magnetars: They can emit bursts of low energy gamma rays in a pattern never before seen in any other astronomical object. It's unclear why this should be, but magnetars themselves are poorly understood, with dozens of theories about how they produce radio and gamma ray bursts. The recognition of this unusual pattern of gamma ray activity ...

Bacteria are key to vaginal health, UArizona health sciences researchers say

2021-07-13
Bacterial vaginosis is the most common and recurrent gynecological condition affecting nearly 30% of women between the ages of 15 and 44, according to the U.S. Centers for Disease Control and Prevention. A University of Arizona Health Sciences-led study recently identified a specific bacteria family and uncovered how it contributes to bacterial vaginosis, paving the way for new insights into disease prevention and treatment. Led by Melissa Herbst-Kralovetz, PhD, a member of the BIO5 Institute and associate professor of basic medical sciences at the College of Medicine - Phoenix, researchers found that members of the Veillonellaceae bacteria family contribute to an increase in inflammation and cell death, and alter the acidity of the cervical microenvironment. These changes support bacterial ...

Microcrystal electron diffraction supports a new drug development pipeline

Microcrystal electron diffraction supports a new drug development pipeline
2021-07-13
CAMBRIDGE July 13, 2021 - To date, solving structures of potential therapeutics using X-ray diffraction (XRD) has been an assumed, pivotal step in the drug development process. But a recent paper by a team of researchers led by NanoImaging Services shows how microcrystal electron diffraction (MicroED) is growing to obtain the structures of potential pharmaceuticals. Three-dimensional crystal structures that show the relative positions of atoms, bonds and intramolecular interactions are needed to understand stability, reactivity, solubility and, ultimately, suitability ...

COVID-19 hospitalization and mortality: Sex differences

COVID-19 hospitalization and mortality: Sex differences
2021-07-13
New Rochelle, NY, July 13, 2021--Males with COVID-19 had significantly higher rates of hospitalization and of transfer to the intensive care unit (ICU) according to a new study. A higher percentage of males died of COVID-19 compared to females, as reported in the study published in the peer-reviewed Journal of Women's Health. Click here to read the article now. Joanne Michelle Gomez, MD, Rush University Medical Center, and coauthors, studied the first 8,108 positive COVID-19 patients that presented to the Rush University System from March 1-June 21, 2020. Nineteen percent of males required hospitalization, compared to 13% of females. ...

"Long COVID": More than a quarter of COVID-19 patients still symptomatic after 6 months

2021-07-13
In a new study of adults from the general population who were infected with COVID-19 in 2020, more than a quarter report not having fully recovered after six to eight months. Those findings are described this week in the open-access journal PLOS ONE by Milo Puhan and colleagues at the University of Zurich, Switzerland. While initial public health responses to the SARS-CoV-2 virus focused on reducing the acute burden of COVID-19, a growing body of evidence indicates that the infection can also result in longer-term physical and mental health consequences. These long-term consequences, currently referred to as "post-COVID-19 syndrome" or "Long Covid" are ...

Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality

Allocating COVID-19 vaccines based on health and socioeconomics could reduce mortality
2021-07-13
COVID-19 vaccination strategies in the United States are informed by individual characteristics such as age and occupation. A study published in the open access journal PLOS Medicine by Sasikiran Kandula and Jeffrey Shaman of Columbia University, New York, United States suggests that including socioeconomic indicators as prioritization criteria for vaccination may help minimize severe outcomes, particularly deaths. Efforts to reduce COVID-19 mortality rates in the US have focused on prioritizing vaccination initially for those at a higher risk of severe outcomes. The effectiveness of population-level ...

Allocating COVID vaccines based on health and socioeconomic factors could cut mortality

Allocating COVID vaccines based on health and socioeconomic factors could cut mortality
2021-07-13
An estimated 43 percent of the variability in U.S. COVID-19 mortality is linked with county-level socioeconomic indicators and health vulnerabilities, with the strongest association seen in the proportions of people living with chronic kidney disease and living in nursing homes. The study by Columbia University Mailman School of Public Health researchers suggests that allocating vaccines based on these factors could help minimize severe outcomes, particularly deaths. Results are published in the open-access journal PLOS Medicine. "It is well known that COVID-19 deaths are concentrated in communities with underlying ...

Global study reveals effectiveness of protected areas

Global study reveals effectiveness of protected areas
2021-07-13
Researchers have conducted a global study on the effectiveness of recently established protected areas in preventing forest loss The study explores protected area performance by countries, with South Africa, Cambodia, Latvia, Guatemala, Uruguay, Brazil and New Zealand leading the way in the effectiveness of their protected areas The research team estimated that overall, protected areas established between 2000-2012 prevented 86,062 square kilometers of forest loss If all countries had protected areas that were as effective as their top-performing neighbor, then an additional 33,020 square kilometers of forests would have been saved Machine learning found that agricultural ...

Species of gut bacteria linked to enhanced cognition and language skills in infant boys

2021-07-13
The University of Alberta-led research followed more than 400 infants from the CHILD Cohort Study (CHILD) at its Edmonton site. Boys with a gut bacterial composition that was high in the bacteria Bacteroidetes at one year of age were found to have more advanced cognition and language skills one year later. The finding was specific to male children. "It's well known that female children score higher (at early ages), especially in cognition and language," said Anita Kozyrskyj, a professor of pediatrics at the U of A and principal investigator of the SyMBIOTA (Synergy in Microbiota) laboratory. "But when it comes to gut microbial ...

Air pollution exposure linked to poor academics in childhood

2021-07-13
Children exposed to elevated levels of air pollution may be more likely to have poor inhibitory control during late childhood and poor academic skills in early adolescence, including spelling, reading comprehension, and math skills. Difficulty with inhibition in late childhood was found to be a precursor to later air pollution-related academic problems. Interventions that target inhibitory control might improve outcomes. Results of the study by researchers at the Columbia Center for Children's Environmental Health (CCCEH) at Columbia University Mailman School of Public Health and Columbia University Irving Medical Center are published in the journal Environmental ...

Lesbian, gay, bisexual smokers are at a higher risk for smoking menthol cigarettes

2021-07-13
Compared with heterosexual smokers, menthol cigarette smoking is higher among lesbian, gay and bisexual cigarette smokers, according to a Rutgers-led study, especially among bisexual and lesbian/gay female cigarette smokers. The study, published in the journal Nicotine & Tobacco Research, examined national data from 2015 to 2019 of individuals ages 18 years and older by sex and sexual identity and found that among smokers, 54 and 50 percent of bisexual and lesbian/gay females smokers preferred menthol cigarettes, respectively, compared with 39 percent of smokers overall. This study comes in the wake of plans by the U.S. Food and Drug Administration to ban menthol cigarettes; a move that researchers say is ...

5D imaging of ultrafast phenomena

5D imaging of ultrafast phenomena
2021-07-13
Information-rich optical imaging can provide multidimensional information to enable observation and analysis of a detected target, contributing insights into mysterious and unknown worlds. With its ability to capture dynamic scenes on picosecond—and even femtosecond—timescales, ultrafast multidimensional optical imaging has important applications in the detection of the ultrafast phenomena in physics, chemistry, and biology. While pump-probe-based ultrafast imaging can acquire high-resolution multidimensional information, it cannot adequately capture unstable or irreversible transient scenes. Fortunately, compressed ultrafast photography (CUP), based ...

Rats prefer to help their own kind; humans may be similarly wired

Rats prefer to help their own kind; humans may be similarly wired
2021-07-13
A decade after scientists discovered that lab rats will rescue a fellow rat in distress, but not a rat they consider an outsider, new research from the University of California, Berkeley, pinpoints the brain regions that drive rats to prioritize their nearest and dearest in times of crisis. It also suggests humans may share the same neural bias. The findings, published today, Tuesday, July 13, in the journal eLife, suggest that altruism, whether in rodents or humans, is motivated by social bonding and familiarity rather than sympathy or guilt. "We have found that the group identity ...

Long-term memory setup requires a reliable delivery crew

Long-term memory setup requires a reliable delivery crew
2021-07-13
JUPITER, FL - The brain is wired for learning. With each experience, our neurons branch out to make new connections, laying down the circuitry of our long-term memories. Scientists call this trait plasticity, referring to an ability to adapt and change with experience. For plasticity to happen, our neurons' synapses, or connection points, must constantly remodel and adapt, too. The mechanics underlying neurons' synaptic plasticity have become clearer, thanks to new research from the lab of Scripps Research neuroscientist Sathya Puthanveettil, PhD. Scientists have learned that synaptic plasticity requires a complex relay from the neuron's cell body to its dendrite arms and its synapse junctions. Like a 24-hour port and highway network, an internal ...

Farm marketing success linked to natural, cultural assets

2021-07-13
ITHACA, N.Y. - Direct farm marketing efforts, such as farmers markets and roadside stands, are more successful in communities with more nonprofits, social enterprises and creative industries, according to a team including Cornell University researchers, who created a nationwide database of assets to help municipalities craft community-specific development plans. While many municipalities seek to encourage direct-to-consumer (DTC) marketing - an important factor in farmers' livelihoods - the success of their efforts hinges on a wide array of community resources, or capital assets, with natural and cultural ...

The two-thousand-year-old mystery of the havoc-wreaking worm

The two-thousand-year-old mystery of the havoc-wreaking worm
2021-07-13
AMHERST, Mass. - Humans have known for over two thousand years that shipworms, a worm-like mollusk, are responsible for damage to wooden boats, docks, dikes and piers. Yet new research from the University of Massachusetts Amherst published in Frontiers in Microbiology reveals that we still don't know the most basic thing about them: how they eat. "It's unbelievable," says Reuben Shipway, adjunct assistant professor in microbiology at UMass Amherst, research fellow at the Centre for Enzyme Innovation at the University of Portsmouth, UK, and one of the paper's authors. "The ancient Greeks wrote about them, Christopher Columbus lost his fleet due to what he called 'the havoc which the worm had wrought,' and, today, shipworms cause billions of dollars of damage a year." Shipworms ...

Eating whole grains linked to smaller increases in waist size, blood pressure, blood sugar

2021-07-13
Middle- to older-aged adults who ate at least three servings of whole grains daily had smaller increases in waist size, blood pressure, and blood sugar levels over time compared to those who ate less than one-half serving per day, according to new research. Published July 13, 2021, in the Journal of Nutrition, the study by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University examined how whole- and refined-grain intake over time impacted five risk factors of heart disease: Waist size, blood pressure, blood sugar, triglyceride, and HDL ("good") cholesterol. Using data from the Framingham Heart Study Offspring ...

How well do consumers understand their dairy purchases?

2021-07-13
Philadelphia, July 13, 2021 - Consumers may have less trust in food processes that they don't understand, and animal-based foods may be subject to more uninformed scrutiny than other foods due to consumers' perception of higher risk. Dairy producers can benefit from understanding how consumers interpret unfamiliar terms and claims on dairy product labels. In a new END ...

COVID-causing coronavirus following predictable mutational footsteps

COVID-causing coronavirus following predictable mutational footsteps
2021-07-13
New research from the University of Nebraska-Lincoln has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem to run in the family -- or at least the genus of coronaviruses most dangerous to humans. After comparing the early evolution of SARS-CoV-2 against that of its closest relatives, the betacoronaviruses, the Nebraska team found that SARS-CoV-2 mutations are occurring in essentially the same locations, both genetically and structurally. The mutational similarities between SARS-CoV-2 and its predecessors, including the human-infecting SARS-CoV-1 and MERS-CoV, could help inform predictions of how the COVID-causing virus will continue to evolve, the researchers ...

Taming the Huntington's disease proteome: Mass spectrometry may provide answers

2021-07-13
Amsterdam, July 13, 2021 - Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease. This END ...

What you say in the first minute after a vaccine can be key in reducing a child's distress

2021-07-13
YorkU pain research finds what you say in the first minute after a vaccine can be key in reducing a child's future distress New study finds it's not just what say, but when you say it that can keep preschoolers calmer during vaccinations TORONTO, July 13, 2021 - As we look forward to a fall with hopefully one of the most important vaccination uptakes of children in a generation, a new study provides insights to help parents with reducing post-vaccination distress in younger kids. The study, published in END ...

US-wide, non-white neighborhoods are hotter than white ones

US-wide, non-white neighborhoods are hotter than white ones
2021-07-13
WASHINGTON--In cities and towns across the United States, neighborhoods with more Black, Hispanic and Asian residents experience hotter temperatures during summer heatwaves than nearby white residents, a new study finds. It is the first to show that the trend, documented in some major cities, is widespread, even in small towns, nationwide.   According to the new nationwide study, these racial disparities exist because non-white neighborhoods tend to be more densely built up with buildings and pavement that trap heat and have fewer trees to cool the landscape.    "Urban climate is different from temperatures outside the city," said co-author Susanne Benz, an ...

Are silver nanoparticles a silver bullet against microbes?

Are silver nanoparticles a silver bullet against microbes?
2021-07-13
Antimicrobials are used to kill or slow the growth of bacteria, viruses and other microorganisms. They can be in the form of antibiotics, used to treat bodily infections, or as an additive or coating on commercial products used to keep germs at bay. These life-saving tools are essential to preventing and treating infections in humans, animals and plants, but they also pose a global threat to public health when microorganisms develop resistance to them, a concept known as antimicrobial resistance. One of the main drivers of antimicrobial resistance is the misuse and overuse of antimicrobial agents, which includes silver nanoparticles, ...

Study: Racial/ethnic and language inequities in ways patients obtain COVID-19 testing

2021-07-13
The COVID-19 pandemic caused an unprecedented disruption to health care delivery, with resources shifted toward telehealth services and mass viral testing. While early studies in the pandemic highlighted differences in health care utilization among patients with commercial insurance, data from publicly insured or uninsured "safety-net" patient populations continue to emerge. A recent study from researchers at the University of Minnesota and Hennepin Healthcare Research Institute (HHRI) is among the first to examine how different socio-demographic groups used telehealth, outpatient (i.e., clinic), emergency department and inpatient (i.e., hospital) care to test for SARS-CoV-2, the virus that causes COVID-19. ...

Higher-order topological superconductivity in monolayer Fe(Te,Se)

Higher-order topological superconductivity in monolayer Fe(Te,Se)
2021-07-13
In particle physics, a Majorana Fermion is charge neutral and its antiparticle is just itself. In condensed matter physics, a Majorana zero mode (MZM) is a quasi-particle excitation, which appears in the surfaces or edges of topological superconductors. Unlike the ordinary particles or quasi-particles that obey boson or fermion statistics, MZM obeys non-abelian statistics, a key property that makes MZM the building block for realizing topological quantum computation. Currently major experimental efforts focus on heterostructures made of superconductors and spin-orbit coupled systems (such as semiconducting nano-wires and topological insulators), where evidences of MZMs have been found. Unambiguous detection and manipulation of MZMs in these heterostructures, ...
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