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Longevity gene from naked mole rats extends lifespan of mice
Science 2023-08-23

Longevity gene from naked mole rats extends lifespan of mice

In a groundbreaking endeavor, researchers at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse’s lifespan. Naked mole rats, known for their long lifespans and exceptional resistance to age-related diseases, have long captured the attention of the scientific community. By introducing a specific gene responsible for enhanced cellular repair and protection into mice, the Rochester researchers have opened exciting possibilities for unlocking the secrets of aging and extending human lifespan. “Our study provides a proof of principle ...
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Science 2023-08-23

Ice-free preservation method holds promise to protect reefs

As ocean temperatures rise, coral reefs face increasing threats as ecosystem damage has accelerated in recent decades. The ability to preserve and revive biodiverse coral samples has become an essential priority for the health and future of the world’s oceans. A Texas A&M University-led interdisciplinary team of researchers demonstrated that live coral can be preserved through a new technique called “isochoric vitrification.” This process takes selected coral fragments through the stages of cryopreservation, ...
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Editorial: A macrophage is a macrophage is a macrophage—in metastasis
Science 2023-08-23

Editorial: A macrophage is a macrophage is a macrophage—in metastasis

“We hope that these results will inform future attempts at anti-macrophage therapy and lead to better outcomes for patients in the not-too-distant future.”  BUFFALO, NY- August 23, 2023 – A new editorial paper was published in Oncotarget's Volume 14 on June 6, 2023, entitled, “A macrophage is a macrophage is a macrophage—in metastasis.” In this new editorial, researcher Thomas T. Tapmeier from Monash University, Hudson Institute of Medical Research and University of Oxford discusses a recent study he co-authored on how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma. Macrophages have important roles ...
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Deforestation limits nesting habitat for cavity-nesting birds
Environment 2023-08-23

Deforestation limits nesting habitat for cavity-nesting birds

With an extendable pole fitted with a small camera, Alison Ke could get a clear view of the inside of a nest box, including one time when a small, green Pacific parrotlet laid eggs. Ke, who earned a Ph.D. in ecology from UC Davis, led a research project to find out how converting rainforest to farmland affects the habitat of birds who rely on tree holes, or cavities, for nesting. Ke worked closely with local scientists and community members to study birds around the Mache-Chindul Ecological Reserve, an area in northwest Ecuador that has experienced rapid deforestation and agricultural expansion in the past 50 years. Their study, ...
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Medicine 2023-08-23

Brain lesions associated with memory loss in multiple sclerosis linked to common brain circuit

Between 30 to 50 percent of people living with multiple sclerosis (MS) will experience memory problems but the cause is uncertain. Brain lesions are the hallmark imaging sign used to diagnose MS and are often associated with memory dysfunction. However, increased MS brain lesions are not specific to memory problems and are also associated with fatigue, walking difficulty and other common MS symptoms. Previous studies that attempted to align the anatomy of lesions associated with memory problems in MS led to conflicting ...
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Science 2023-08-23

2024 Hertz Fellowship application now open

The Fannie and John Hertz Foundation, an organization dedicated to empowering the nation’s most promising innovators in science and technology, announced today that it is accepting applications for the 2024 Hertz Fellowship awards. The Hertz Foundation has been granting fellowships to empower the nation’s most promising young minds in science and technology since 1963. Hertz Fellows receive five years of funding, which offers flexibility and freedom from the traditional constraints of graduate training and the independence needed to pursue research to advance our ...
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Medicine 2023-08-23

Mayo researchers find vaccine may reduce severity of long-haul COVID symptoms

ROCHESTER, Minn. — Getting a COVID-19 vaccine may not only reduce a person's risk of getting long-haul COVID, but also could mean fewer symptoms for people who develop the condition. Mayo Clinic researchers discovered that long-haul COVID patients who were vaccinated before contracting the virus were less likely to experience symptoms such as abdominal pain, chest pain, dizziness, and shortness of breath, according to a study published in the Journal of Investigative Medicine. The study is believed to be among the first to examine COVID-19 vaccines' potential to reduce ...
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MSU research suggests natural selection can slow evolution, maintain similarities across generations
Science 2023-08-23

MSU research suggests natural selection can slow evolution, maintain similarities across generations

MSU research suggests natural selection can slow evolution, maintain similarities across generations Highlights: New research from Michigan State University suggests that natural selection, famous for rewarding advantageous differences in organisms, can also preserve similarities. Reporting in the journals New Phytologist and Evolution, the researchers worked with a plant called wild radish and its stamens, or pollen-producing parts, two of which are short and four are long. Roughly 55 million years ago, wild radish ancestors had stamens of equal length. The team selectively bred — or artificially selected — ...
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Science 2023-08-23

New modeling method helps to understand extreme heat waves

ITHACA, N.Y. - To prepare for extreme heat waves around the world – particularly in places known for cool summers – climate-simulation models that include a new computing concept may save tens of thousands of lives. The concept, called “ensemble boosting,” uses computationally efficient modeling to simulate a large set of extreme but plausible heat waves, all while avoiding hundreds of hours of expensive calculations on large computers. The study on the new modeling method, led by scientists at ETH Zurich, Switzerland and Cornell University, was published Aug. ...
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Science 2023-08-23

Insurance data reveal that vasectomies are becoming more common in the U.S.

In the wake of the 2022 Supreme Court ruling in Dobbs v. Jackson Women's Health Organization that overturned Roe v. Wade, researchers at the University of Chicago set out to investigate whether anticipation of restricted abortion access increased interest in vasectomies in the preceding years. In a new analysis, they found that vasectomy rates in the United States witnessed a remarkable surge from 2014 to 2021, as more men opted for the outpatient surgical procedure that offers permanent contraception by preventing ...
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Researchers target lifecycle of parasite behind Chagas disease
Medicine 2023-08-23

Researchers target lifecycle of parasite behind Chagas disease

Almost everything about insects called kissing bugs is revolting, from the insidious way they bite people’s faces at night to drink their blood while they sleep to the way they spread disease through their poop. Some carry a parasite called Trypanosoma cruzi that causes Chagas disease, a leading cause of disability and premature death in the Americas. Left untreated, Chagas disease can cause serious heart and digestive problems. It’s showing up more and more in patients in the United States. Now researchers at the University of Cincinnati are investigating ...
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Science 2023-08-23

Better or different? How brand differentiation affects pay and profits

DURHAM, N.C. -- New research finds brands that leverage a reputation for quality to pay employees less risk eroding profits. The paper, published online June 12 in the Journal of Marketing Research and authored by researchers from Duke University, London Business School and Texas A&M University, shows that vertical brand differentiation (being perceived as better) is associated with lower pay, whereas horizontal brand differentiation (being perceived as different) is associated with higher pay. High-quality brands taking advantage of brand cachet to pay employees less erodes profits due to negative effects on employee productivity ...
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ORNL wins six R&D 100 research awards
Science 2023-08-23

ORNL wins six R&D 100 research awards

Technologies developed by researchers at the Department of Energy’s Oak Ridge National Laboratory have received six 2023 R&D 100 Awards.   R&D World magazine announced the winners from their selection of finalists announced last week. The winners will be recognized at the organization’s award ceremony November 16 in San Diego, California. “ORNL strives to deliver technological solutions for the nation’s toughest problems,” said interim ORNL Director Jeff Smith. “This year’s R&D 100 Awards are a reminder of how hard our scientists and engineers work to accomplish that feat.” Often referred ...
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Education levels and child age shaped caregivers’ concerns amid Covid-19 pandemic, NIH study suggests
Medicine 2023-08-23

Education levels and child age shaped caregivers’ concerns amid Covid-19 pandemic, NIH study suggests

A caregiver’s education level and their child’s age played large roles in determining their primary sources of stress during the COVID-19 pandemic, researchers found in a recent study by NIH’s Environmental influences on Child Health Outcomes (ECHO) Program. Caregivers who had less than a high school education were less likely to work remotely and were more worried about finances, childcare, and access to necessities like food. Caregivers with a master’s degree or higher reported greater concern about social distancing and impacts on their work. The ...
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Social Science 2023-08-23

There’s a growing split in the middle of the economic distribution for Americans nearing retirement age

A study by health policy researchers at Columbia University Mailman School of Public Health and University of Southern California projects that the expected health and economic well-being of Americans nearing retirement age in the lower half of the economic distribution today is no better than that of their counterparts more than two decades ago. The focus of most policy efforts has been to support the most disadvantaged, generally considered the lowest 15 percent of the population with respect to financial resources. Less attention has been drawn to those between the 15th and ...
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Science 2023-08-23

Lower-middle class Americans near retirement are worse off than 20 years ago, new USC and Columbia study shows

Lower-middle class Americans nearing retirement age are worse off than their counterparts more than two decades ago, while upper-middle Americans have largely seen their life expectancy and wealth improve. Policymakers, meanwhile, overlook the lower middle group of Americans who don’t qualify for many assistance programs. That’s according to a new study by the USC Schaeffer Center for Health Policy & Economics and the Columbia University Mailman School of Public Health. Using data from the Health and Retirement Survey and a microsimulation called the Future Elderly Model, researchers estimated future life expectancy and disability for cohorts of individuals ...
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Medicine 2023-08-23

Small study suggests long COVID may affect more people than previously thought

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, AUGUST 23, 2023 MINNEAPOLIS – Millions of Americans were exposed to SARS-CoV-2, the virus that causes COVID-19, early in the pandemic but could not get diagnosed due to testing limitations. Many of those people developed a post-viral syndrome with symptoms similar to those of long COVID.  In a new study of a small group of those people, their immune response shows that 41% had evidence of SARS-CoV-2 exposure. The study is published in the August 23, 2023, online issue of Neurology® Neuroimmunology & Neuroinflammation, an official journal of the American Academy of Neurology. Long COVID was defined as symptoms persisting ...
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Medicine 2023-08-23

A new targeted treatment shows promise for select patients with stomach cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker. Results from the GLOW study, published July 31 in Nature Medicine, together with results from the parallel SPOTLIGHT study that evaluated zolbetuximab with an alternative standard chemotherapy, prompted the ...
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Shift work may impair memory and cognition, per data on nearly 50,000 Canadian adults
Social Science 2023-08-23

Shift work may impair memory and cognition, per data on nearly 50,000 Canadian adults

Exposure to night shift work and rotating shift work is associated with an increased risk of cognitive impairment among middle-aged and older adults, according to a new study published this week in the open-access journal PLOS ONE by Durdana Khan of York University, Canada, and colleagues. Previous research has established that shift work, which refers to any work schedule that occurs outside the traditional 9am to 5pm working hours, has significant health impacts. In the new work, the researchers analyzed data on 47,811 adults in the Canadian Longitudinal Study. The dataset included ...
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Opportunistic sperm and northern bottlenose whales frequently observed swimming behind deep-sea trawler net to feed on escaping fish
Science 2023-08-23

Opportunistic sperm and northern bottlenose whales frequently observed swimming behind deep-sea trawler net to feed on escaping fish

Sperm and northern bottlenose whales were frequently observed following a trawler off the coast of Newfoundland to feed on fish escaping from the net as it was hauled in, according to a study published August 23, 2023 in the open-access journal PLOS ONE by Usua Oyarbide from Plentzia Marine Station–Univ Basque Country, Spain, and colleagues. In this study, the authors looked at how cetaceans interacted with a deep-sea trawler fishing in the western North Atlantic off the coast of Newfoundland in 2007. Oyarbide tracked whale encounters over 50 days between July 20 and September 13, 2007, while onboard the trawler as a North Atlantic Fisheries Organization observer. Sperm whales (Physeter ...
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Scientists solve mystery of why thousands of octopus migrate to deep-sea thermal springs
Social Science 2023-08-23

Scientists solve mystery of why thousands of octopus migrate to deep-sea thermal springs

In 2018, researchers from NOAA’s Monterey Bay National Marine Sanctuary and Nautilus Live observed thousands of octopus nesting on the deep seafloor off the Central California coast. The discovery of the “Octopus Garden” captured the curiosity of millions of people around the world, including MBARI scientists. For three years, MBARI and collaborators used high-tech tools to monitor the Octopus Garden and learn exactly why this site is so attractive for deep-sea octopus. In a new study published today in Science Advances, a team of researchers from MBARI, NOAA's Monterey Bay National Marine Sanctuary, Moss Landing Marine Laboratories, the University ...
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Malaysian rock art found to depict elite–Indigenous conflict
Science 2023-08-23

Malaysian rock art found to depict elite–Indigenous conflict

A team of researchers led by the Griffith Centre for Social and Cultural Research in collaboration with The Sarawak Museum Department have become the first to date drawings of Gua Sireh Cave in Sarawak, uncovering a sad story of conflict in the process. The limestone cave of Gua Sireh in western Sarawak (Malaysian Borneo) is famous for the hundreds of charcoal drawings lining the walls of its main chambers, attracting hundreds of visitors each year. Approximately 55km southeast of Sarawak’s Capital, Kuching, the site is managed by the Bidayuh (local Indigenous peoples) in collaboration with The Sarawak Museum Department, ...
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How a cup of water can unlock the secrets of our Universe
Space 2023-08-23

How a cup of water can unlock the secrets of our Universe

Researchers from Queen Mary University of London have made a discovery that could change our understanding of the universe. In their study published in Science Advances, they reveal, for the first time, that there is a range in which fundamental constants can vary, allowing for the viscosity needed for life processes to occur within and between living cells. This is an important piece of the puzzle in determining where these constants come from and how they impact life as we know it.  In 2020, the same team found that the viscosity of liquids is determined by fundamental physical constants, setting a limit on how runny a ...
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How neurons grow comfortable in their own skin
Medicine 2023-08-23

How neurons grow comfortable in their own skin

Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell.  If affirmed in further studies, the findings could eventually help researchers develop therapies to regenerate damaged or diseased nerves, the authors say, or better understand what goes awry in congenital neuropathies, conditions in individuals born with ...
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A better understanding of myalgic encephalomyelitis/chronic fatigue syndrome could benefit long COVID patients
Medicine 2023-08-23

A better understanding of myalgic encephalomyelitis/chronic fatigue syndrome could benefit long COVID patients

Amsterdam, August 23, 2023 – While myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID are not the same disease, they appear to have features of overlapping biological and symptomatic presentations. Many people with Long COVID meet the diagnostic criteria of ME/CFS. Long COVID scientists and clinicians could expedite research and care protocols by utilizing information and experiences gained from the ME/CFS community. A special section of WORK: A Journal of Prevention, Assessment & Rehabilitation aims to provide a ...
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