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New guidance to help diagnose hoarding disorder

2023-05-04
Experts from Anglia Ruskin University (ARU) have published new guidance to help doctors correctly diagnose hoarding disorder. Hoarding disorder affects around 2% of the population but remains a largely misunderstood mental health condition. It was only added to the International Classification of Diseases in 2019, having previously been classified under Obsessive Compulsive Disorder (OCD). Published in the British Journal of General Practice, the new guidance was written by Dr Sharon Morein and Dr Sanjiv Ahluwalia of Anglia Ruskin University (ARU) in Cambridge, England, to help health professionals spot the signs of hoarding disorder and intervene. ARU experts have also organised a free ...

GlyNAC supplementation improves cognitive decline and brain health in aging

2023-05-04
As people get older, they aspire to live healthy lives as free as possible from the natural decline of cognitive abilities that occurs with aging. At Baylor College of Medicine, researchers have been studying the biological underpinnings of age-associated cognitive decline and developing nutritional strategies to promote healthy brain aging. They report today in the journal Antioxidants that supplementing GlyNAC – a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione – improved or reversed age-associated cognitive decline in old mice and improved ...

Three NYU faculty elected to the National Academy of Sciences

2023-05-04
Three New York University faculty have been elected to the National Academy of Sciences: Moses Chao, a professor at NYU Grossman School of Medicine; Glennys Farrar, a professor in NYU’s Department of Physics; and Subhash Khot, a professor in NYU’s Courant Institute of Mathematical Sciences. This year’s election of 120 new members and 23 international members were chosen “in recognition of their distinguished and continuing achievements in original research,” the academy announced.  Moses Chau, a professor of cell biology, psychiatry, and neuroscience and physiology and part of ...

Criteria for selecting who can enroll in multiple myeloma clinical trials may exclude patients from racial and ethnic minorities

2023-05-04
(WASHINGTON, May 4, 2023) – Numerous studies have shown that people from racial and ethnic minority groups are underrepresented in clinical trials of new medical treatments for multiple myeloma. A study published today in Blood suggests that, for clinical trials of new treatments for multiple myeloma (a type of blood cancer), one reason for this underrepresentation may be that the parameters set to determine who can – and cannot – enroll in trials disproportionately exclude minority patients.  “Our ...

Wistar scientists discover innate tumor suppression mechanism

Wistar scientists discover innate tumor suppression mechanism
2023-05-04
PHILADELPHIA — (MAY 4, 2023) — The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ago, researchers have so far been unsuccessful at determining exactly how it works. Now, in a recent study published in Cancer Discovery, a journal of the American Association for Cancer Research, researchers at The Wistar Institute have uncovered a key mechanism ...

Wind energy from a 3D printer

Wind energy from a 3D printer
2023-05-04
A pilot project for energy self-sufficient schools is now starting in the County of Friesland, Northern Germany, in which school buildings will be equipped with vertical-axis wind turbines. This will be facilitated by a research group led by Professor Uygun from Constructor University. This group is studying and developing vertical wind turbines, which will be produced in its own 3D printer on the campus in Bremen and will be tested in practice within this project. This creates a fully functional test field that provides important data and experience for technology transfer. In the current energy ...

Escorting a key immune protein to its demise to control inflammation

Escorting a key immune protein to its demise to control inflammation
2023-05-04
Monash University researchers have discovered a key mechanism in the body’s immune system that helps control the inflammatory response to infection. The discovery could help pave the way for more targeted therapies in a range of inflammatory conditions, such as autoimmunity and neuroinflammatory disease. The innate immune system is the body’s first line of defence against pathogens. Innate immune proteins detect foreign bodies such as bacteria and viruses and respond by mounting a protective inflammatory ...

Nutrition research continues to support the health benefits of regular watermelon consumption

2023-05-04
There’s no question that watermelon is both delicious and nutritious, but new research underscores this nutrient-rich fruit’s contributions to overall diet quality and heart health. A recent study published in Nutrients suggests that watermelon can increase nutrient intake and overall diet quality in both children and adults.1 The study analyzed National Health and Nutrition Examination Survey (NHANES) data and found that total diet quality was higher in watermelon consumers as compared to non-consumers. ...

National Comprehensive Cancer Network honors cancer leaders who guide the future of care

National Comprehensive Cancer Network honors cancer leaders who guide the future of care
2023-05-04
PLYMOUTH MEETING, PA [May 4, 2023] —The National Comprehensive Cancer Network® (NCCN®) has announced the 2023 recipients of awards honoring individuals who made a remarkable difference in improving the lives of people with cancer over the past year. 2023 NCCN Award Recipients: Theresa J. Franco, MSN, RN, Vice President, Cancer Clinical Operations, Nebraska Medicine NCCN Board of Producers Award recipient for exemplary service of NCCN’s mission F. Marc Stewart, MD, Professor, Vice Chair, Department of Hematology and ...

Local entrepreneurs tackling social change, health inequity invited to apply for financial grants

2023-05-04
DALLAS, May 4, 2023 — A recent study revealed that, in the United States, Black and Latinx entrepreneurs receive only 2.6% of venture capital investment. [1]  The American Heart Association®, the world’s leading nonprofit organization focused on longer, healthier lives for all, has opened the application window for submissions to the EmPOWERED to Serve Business Accelerator™. The Accelerator program has been established to support local communities, small businesses, social entrepreneurs and innovators who are working to increase health equity and create groundbreaking social change at the zip code level. Now in its seventh year, the Business ...

Marine seagrass meadows show resilience to ‘bounce back’ after die-offs

Marine seagrass meadows show resilience to ‘bounce back’ after die-offs
2023-05-04
In Florida alone, thousands of acres of marine seagrass beds have died. Major seagrass die-offs also are occurring around the world. Stressors such as high temperature, hypersalinity and hypoxia or lack of oxygen affect seagrasses’ ability to resist and recover from these stressor-related mortality events or when disturbances lead to seagrass die-off events. Seagrass die-offs also are linked to exposure to sediment-derived hydrogen sulfide, a well-known phytotoxin that accumulates as seagrass ecosystems become more enriched in nutrients. While hydrogen sulfide intrusion into seagrass tissue is considered a leading cause of recurring mortality ...

Engineering molecular interactions with machine learning

Engineering molecular interactions with machine learning
2023-05-04
In 2019, scientists in the joint School of Engineering and School of Life Sciences Laboratory of Protein Design and Immunoengineering (LPDI) led by Bruno Correia developed MaSIF: a machine learning-driven method for scanning millions of protein surfaces within minutes to analyze their structure and functional properties. The researchers’ ultimate goal was to computationally design protein interactions by finding optimal matches between molecules based on their surface chemical and geometric ‘fingerprints’. Four years later, they have achieved ...

High school students learn the basics of base editing to cure “GFP-itis”

2023-05-04
Genome editing is used to modify the genes of living organisms to elicit certain traits, such as climate-resilient crops or treating human disease at the genetic level. It has become increasingly popular in agriculture, medicine and basic science research over the past decade, and will continue to be relevant and utilized well into the future. Given this prevalence, researchers at the University of California San Diego have started an outreach program that introduces genome-editing technologies to high school students. Assistant Professor of Chemistry and Biochemistry Alexis Komor, and Ph.D. candidates Mallory ...

Awardees named for $15 million research project on CVD health impacts of chronic stress

2023-05-04
DALLAS, May 4, 2023 — Teams of research scientists from three universities will lead an innovative $15 million project to study the biological mechanisms of chronic stress that can increase cardiovascular disease risk. The Strategically Focused Research Network (SFRN) on Biologic Pathways of Chronic Psychosocial Stressors on Cardiovascular Health of the American Heart Association, the world’s leading voluntary organization dedicated to a world of longer, healthier lives, will focus on learning more about how the body responds to chronic stress, as well as how certain interventions may help reduce health risks. Chronic stress is recognized as an independent ...

Understanding self-directed ageism

2023-05-04
The study led by Professor Julie Henry from UQ’s School of Psychology looked at why self-directed ageism is common. Cognitive changes make it difficult for older people to challenge internalised ageist beliefs. Image: Adobe. “Older people are regularly exposed to ageism such as negative assumptions about their worth, capacity or level of understanding, as well as jokes about older age,” Professor Henry said. “At the same time, as we grow older, we rely more strongly on prior knowledge and cues from our environment to guide how we feel, think and ...

Amsterdam UMC leads an AI-powered hunt for high-risk vascular patients

2023-05-04
Every year 18 million people die from cardiovascular disease. Making it the deadliest disease in the world. Currently studies focus mainly on the heart, leaving the influence of vascular disease on these large numbers of deaths often out of sight. Despite vascular disorders being a trustworthy indicator for death from heart disease.  VASCUL-AID, a large European study led by Amsterdam UMC, will therefore focus on using AI to predict the worsening of vascular disease in people with an aortic aneurysm or peripheral ...

Chimpanzees combine calls to communicate new meaning

Chimpanzees combine calls to communicate new meaning
2023-05-04
Similar to humans, chimpanzees combine vocalizations into larger communicatively meaningful structures. UZH researchers suggest that this ability might be evolutionarily more ancient than previously thought. A key feature of human language is our ability to combine words into larger compositional phrases i.e. where the meaning of the whole is related to the meaning of the parts. Where this ability came from or how it evolved, however, is less clear. Chimpanzees, our closest-living relative, are known to produce a number of different vocalizations to manage their ...

In first in-utero brain surgery, doctors eliminated symptoms of dangerous condition

2023-05-04
Research Highlights: Using ultrasound guidance, researchers successfully repaired a potentially deadly vascular malformation, called vein of Galen malformation, deep in the brain of a fetus before birth. The malformation, which has massively high blood flow, often leads to heart failure, severe brain injury or possibly death soon after birth. The first in-utero embolization repair was successfully performed on a fetus at 34 weeks and 2 days gestational age. Fetal ultrasound showed an immediate drop in abnormal blood flow through the ...

Team performs first-of-its-kind, in-utero procedure to fix deadly vascular malformation

2023-05-04
In a first, a team from Brigham and Women’s Hospital and Boston Children’s Hospital successfully treated an aggressive vascular malformation in an infant’s brain before birth, avoiding potentially fatal symptoms after delivery. Collaborating researchers and clinicians from Boston Children’s Hospital and Brigham and Women’s Hospital have prevented a deadly developmental condition by treating an aggressive vascular malformation in an infant’s brain before birth. The case, which is the first-ever, in-utero cerebrovascular surgery in the United States, ...

Indigenous people in South America are twice as likely to die from wildfires

Indigenous people in South America are twice as likely to die from wildfires
2023-05-04
A new study, published in IOP Publishing’s journal Environmental Research: Health, reveals that Indigenous people in the Amazon Basin are twice as likely to die prematurely from smoke exposure due to wildfires than the broader South American population. Regions in Peru, Bolivia and Brazil are identified as particular hotspots for smoke exposure, with mortality rates rising to as high as 6 times that of the general population.  The results show that smoke from wildfires in South America account for approximately 12,000 premature deaths every year from 2014 to 2019, with ...

Restricting flavored e-cigarettes may reduce their use among teens and young adults: Study

Restricting flavored e-cigarettes may reduce their use among teens and young adults: Study
2023-05-04
PISCATAWAY, NJ—Getting many adolescents and young adults to stop using e-cigarettes may be as simple as doing away with flavored versions of the product, according to new research in the Journal of Studies on Alcohol and Drugs. This study suggests that a large majority of current users may discontinue their use if the product became available in the tobacco version only.  “The restriction of the availability for certain e-cigarette e-liquid flavors has been considered by various regulatory ...

Alumna named BioOne Ambassador for doctoral work in biological sciences

Alumna named BioOne Ambassador for doctoral work in biological sciences
2023-05-04
Chelsea Kross, a University of Arkansas alumna in biological sciences, earned a 2023 BioOne Ambassador award for her submission “Not all frogs can make it in the city: Using the landscape for targeted conservation,” which summarized research done while working toward her Ph.D. The award recognizes early career researchers in biological, ecological and environmental sciences who demonstrate creative approaches to science communication. “Communicating complex research is critically important to fostering public understanding and support for the sciences,” said Lauren Kane, president and CEO of BioOne. “The 2023 BioOne ...

Remote aerobic walking exercise training feasible for improving cognitive processing speed in persons with multiple sclerosis

Remote aerobic walking exercise training feasible for improving cognitive processing speed in persons with multiple sclerosis
2023-05-04
East Hanover, NJ. May 3, 2023 – Results of a pilot study funded by Kessler Foundation showed that remote aerobic walking exercise training is a feasible and highly promising method for improving cognitive processing speed impairment in fully ambulatory persons with multiple sclerosis (MS). The findings of this single-blind randomized control trial support the design of a randomized, controlled trial in large sample of persons with MS The study, titled "Feasibility of Remotely Delivered and Supported Aerobic Walking Exercise Training for Cognitive Processing Speed Impairment in Fully Ambulatory Persons with Multiple Sclerosis," (doi: ...

Offering genetic testing at the point of care may increase uptake

2023-05-04
Genetic testing for hereditary cancers, such as breast, colon, pancreatic, and ovarian cancer, helps at-risk individuals understand their familial risk for these diseases and make informed decisions about next steps in care. But fewer than 20 percent of at-risk patients utilize this testing, and even fewer engage in genetic counseling after referral, often due to clinical workflow challenges or barriers to care. Amid national efforts to increase access to genetic testing, a new study led by a Boston University School of Public Health researcher has identified a streamlined approach in clinical settings that may help advance ...

Early life abuse may be linked to greater risk of adult premature death

2023-05-04
Physical and sexual abuse in childhood and adolescence could be associated with a greater risk of adult premature death (before age 70), finds research published by The BMJ today. This study extends and refines the existing evidence in this area, and highlights the importance of providing trauma informed care for those who have experienced child abuse, say the researchers. Early life abuse is a global public health issue because it substantially contributes to child death and a range of long term consequences during adulthood. However, the association of childhood or adolescent abuse with total and cause specific premature death during adulthood ...
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