Primary Care Poised to Provide Clinical Guidance, Answers About COVID-19 Testing, Vaccine Administration Researchers examined the role of primary care physicians and other clinicians in delivering vaccinations in the United States. They used two main datasets to create an in-depth analysis of services delivered to Medicare patients, followed by analysis of the Agency for Healthcare Research and Quality's 2017 Medical Expenditure Panel Survey (MEPS) to determine where patients are getting vaccinated and by whom. In the 2017 Medicare Part B Fee-For-Service, primary care physicians provided the largest share of services for vaccinations (46%), followed by mass immunizers (45%), then nurse practitioners/physician ...

Humans are no stranger to coronavirus (CoV) pandemics. Just like SARS-CoV-2 (the virus that causes COVID-19), another member of the coronavirus family--SARS-CoV--caused the severe acute respiratory syndrome (SARS) epidemic across parts of Asia in 2003. But, its spread was contained way faster than COVID-19. So, what makes SARS-CoV-2 so contagious? Both SARS-CoV and SARS-CoV-2 viruses bear "spike proteins" which get inside our cells by binding to a protein called angiotensin-converting enzyme 2 (ACE2) that is found in our cells. However, the SARS-CoV-2 spike (S) protein has been found to have a higher binding affinity (10 to 20 times that of SARS-CoV) to ACE2, thus establishing ...

An international research team, including physics from Russia, has created new glasses for protection against X-ray and gamma radiation. Scientists could select new components that improved the characteristics of the samples and allowed to reduce the amount of lead in the glass composition. Physicists engineered several samples of glasses. One of the latest results - glasses based on barium fluoride - was described by the team in the Optic magazine. But the best results have bismuth borate glasses. Its radiation protection characteristics (mean-free-path, half-value layer) are better than commercial ...

HERSHEY, Pa. -- Electroconvulsive therapy, which may be effective at lowering long-term risks of suicide and death among patients with certain mood disorders, may result in longer hospital stays and increased health care costs, according to Penn State College of Medicine researchers. They said delivering the therapy in outpatient settings may make the treatment more cost-effective. Electroconvulsive therapy (ECT) -- which involves passing small electric currents through the brain to trigger brief seizures while a patient is under anesthesia -- is seldom utilized in the U.S. due ...

Community Health Workers Can Play a Role in Identifying Health-Related Social Needs in Patients Addressing patients' health-related social needs, like housing and food security, is integral to patient care. Federally Qualified Health Centers are leaders in screening for and addressing patients' health-related social needs. However, screening practices vary. This variation is relatively unexplored, particularly with regards to organizational and state policy influences. Study authors conducted in-person, qualitative interviews at Michigan FQHCs to examine how screening approaches vary ...

While several biology techniques have undergone significant technical advances that have allowed their high-throughput implementation, assessing the resistance levels of plant varieties to microbial pathogens remains an arduous and time-consuming task. In response to this, Pujara and collaborators took advantage of the naturally occurring luminescence of a deep-sea shrimp to engineer a light-producing bacterial reporter that allows the quantification of plant resistance levels through imaging. The Nanoluc luciferase (NL) from Oplophorus gracilirostris is a small protein characterized by its high stability and strong brightness. The researchers exploited these features to produce a light emitting bacterial strain from the Pseudomonas syringae species, ...

The Earth contains about one trillion species of microbes -- only about one-tenth of which have been identified. A single human can house 100 trillion microbes, creating a single microbiome that serves an ecosystem of microbes. Microbes connect and transform in myriad ways, creating and combining and separating microbiomes anew. How can we begin to parse out how microbiomes differ, how they are similar, how they evolved and how they may change in the future? An international team of researchers may have the answer. They published a scale-free, fully connected search-based network to explore the connectedness ...

Kumara Raja Sundar, MD, a family physician at Kaiser Permanente of Washington, uses two media synchronicity theory principles - conveyance and convergence - as a framework for choosing the right medium of care for his patients. In this essay, Sundar discusses how operating within this framework changed his own practice and decision making during the COVID-19 pandemic, particularly with the use of telemedicine versus in-person clinic visits. The theory of conveyance focuses on transmitting and processing diverse information to understand a situation. It requires time to analyze data, create patterns and make conclusions. Convergence focuses on discussing pre-processed information to achieve a mutual understanding of it. ...

HOUSTON - A phase II study led by researchers from The University of Texas MD Anderson Cancer Center found that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% objective response rate in patients with advanced malignant peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 expression status and tumor mutation burden. Trial results indicated that the combination was safe and effective in patients with disease progression or intolerance to previous chemotherapy ...

A consortium of modern slavery experts, led by the University of Nottingham, have assisted the Greek government to tackle a humanitarian crisis unfolding in the strawberry fields of southern Greece. Using satellite technology to identify migrant settlements - a technique pioneered by the university's Rights Lab - and working with the Greek authorities, the experts then developed a decision model for which they could prioritise victims that were at highest risk. Leading the study, the Rights Lab combined different data sources and methods to build a set of criteria measuring the extent of labour exploitation in a settlement. The academics then validated these criteria with a government agency and a Non-Governmental ...

The sun provides a daunting source of electromagnetic disarray - chaotic, random energy emitted by the massive ball of gas arrives to Earth in a wide spectrum of radio frequencies. But in that randomness, Stanford researchers have discovered the makings of a powerful tool for monitoring ice and polar changes on Earth and across the solar system. In a new study, a team of glaciologists and electrical engineers show how radio signals naturally emitted by the sun can be turned into a passive radar system for measuring the depth of ice sheets and successfully tested it on a glacier in Greenland. The technique, ...

The treatment of many medical issues like abnormal gait and muscular disorders require an accurate sensing of applied pressure. In this regard, flexible pressure sensors that are simple, lightweight, and low-cost, have garnered considerable attention. These sensors are designed and manufactured through "additive manufacturing," or what is more commonly called "3D printing," using conductive polymer composites as their building blocks. However, all 3D-printed pressure sensors developed so far are limited to sensing applied forces along a single direction only. This is hardly enough for real ...

CHAMPAIGN, Ill. -- Sharing ideas in an online learning environment has a distinct advantage over sharing personal details in driving learner engagement in massive open online courses, more commonly known as MOOCs, says new research co-written by a University of Illinois Urbana-Champaign expert who studies the intersection of marketing and digital environments. Online learning engagement can be increased by nearly one-third by simply prompting students to share course ideas in a discussion forum rather than having them share information about their identity or personal motivations for enrolling, said Unnati Narang, a professor of business administration at the Gies College ...

RESEARCH TRIANGLE PARK, N.C. -- Army-funded research identified a new chemistry approach that could remove micropollutants from the environment. Micropollutants are biological or chemical contaminants that make their way into ground and surface waters in trace quantities. Using a pioneering imaging technique, Cornell University researchers obtained a high-resolution snapshot of how ligands, molecules that bind to other molecules or metals, interact with the surface of nanoparticles. In doing so, they made an unexpected breakthrough discovery. They determined that by varying the concentration of an individual ligand they could control the shape of the particle it attached too. This approach could ...

When there is a gas leak in a large building or at an industrial site, human firefighters currently need to go in with gas sensing instruments. Finding the gas leak may take considerable time, while they are risking their lives. Researchers from TU Delft (the Netherlands), University of Barcelona, and Harvard University have now developed the first swarm of tiny - and hence very safe - drones that can autonomously detect and localize gas sources in cluttered indoor environments. The main challenge the researchers needed to solve was to design the Artificial Intelligence for this complex task that would fit in the tight computational and memory constraints of the tiny drones. They solved this challenge by means of bio-inspired navigation and search strategies. The scientific ...

A new study finds forensics researchers use terms related to ancestry and race in inconsistent ways, and calls for the discipline to adopt a new approach to better account for both the fluidity of populations and how historical events have shaped our skeletal characteristics. "Forensic anthropology is a science, and we need to use terms consistently," says Ann Ross, corresponding author of the study and a professor of biological sciences at North Carolina State University. "Our study both highlights our discipline's challenges in discussing issues ...

Super-thin carbon molecular sieve (CMS) membranes may not be best for separating industrially important chemical mixtures. However, ensuring the CMS film thickness is just right could enable more energy-efficient purification of chemical products, KAUST researchers have shown. CMS membranes, as their name suggests, can purify mixtures of liquids or gases by permitting only certain molecules to pass through their subnanometer-sized pores. Currently, the chemical industry mainly uses heat-based processes such as distillation to separate product mixtures, but these processes consume about 10 percent of global energy output. "This situation is highly unsustainable," says Wojciech Ogieglo, a research scientist at KAUST. "We believe that a good ...

The premise of heated tobacco (HT) is simple: tobacco leaf is heated, never burnt, so avoiding many harmful by-products of combustion for the user. The exhaled 'mist' is correctly termed an aerosol, which is almost invisible and far less dense and pungent than the exhaled smoke from combustible cigarettes. Another advantage of HT is that there are no 'side-stream' emissions to impact air quality (or disturb bystanders - these emissions form part of the ambient smoke that's often known as environmental tobacco smoke (ETS) or 'second-hand' smoke), because unlike a combustible cigarette there is no constantly burning tip. Our previous research suggests that, unlike cigarettes, using our Pulze heated tobacco device causes no negative impact on indoor air quality ...

Researchers have found evidence for an anomalous phase of matter that was predicted to exist in the 1960s. Harnessing its properties could pave the way to new technologies able to share information without energy losses. These results are reported in the journal Science Advances. While investigating a quantum material, the researchers from the University of Cambridge who led the study observed the presence of unexpectedly fast waves of energy rippling through the material when they exposed it to short and intense laser pulses. They were able to make these observations by using a microscopic speed camera that can track small and very fast movement on a scale that is challenging with many other techniques. This technique probes the material with two light pulses: the first one disturbs it ...

In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer's disease. A peptide is a fragment of a protein, and one of the key hallmarks of Alzheimer's disease is the build-up of a specific peptide known as amyloid-β. The team demonstrated that with the aid of ultrasound, their molecule can cross the blood-brain barrier in mice, targeting the part of the brain where the damaging peptide most often accumulates. Alzheimer's disease is the most common form of dementia, affecting approximately 50 million people worldwide. There is a pressing need to develop drugs ...

Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval. World's first 3D printed high tibial osteotomy (HTO) device and procedure developed at University of Bath given approval for UK trials Bespoke titanium alloy HTO implants that fit perfectly are designed to reduce discomfort for knee osteoarthritis patients Sophisticated 3D scanning aims to make surgery quicker and safer New TOKA process could make earlier intervention possible - saving patients decades of pain before surgery becomes viable Intro A ...

Many of us swing through gates every day -- points of entry and exit to a space like a garden, park or subway. Electronics have gates too. These control the flow of information from one place to another by means of an electrical signal. Unlike a garden gate, these gates require control of their opening and closing many times faster than the blink of an eye. Scientists at the U.S. Department of Energy's (DOE) Argonne National Laboratory and the University of Chicago's Pritzker School of Molecular Engineering have devised a unique means of achieving effective gate operation with a form of information processing called electromagnonics. Their pivotal discovery allows real-time control of information transfer between microwave photons and magnons. And it could result in a new generation ...

An important new study by researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory has yielded critical fresh insights into the lithium production process and how it relates to long-term environmental sustainability, particularly in the area of transportation with batteries and electric vehicles. The paper, "Energy, Greenhouse Gas, and Water Life Cycle Analysis of Lithium Carbonate and Lithium Hydroxide Monohydrate from Brine and Ore Resources and Their Use in Lithium Ion Battery Cathodes and Lithium Ion Batteries," in the journal ...

Prof. PAN Jianwei and Prof. ZHANG Jun from University of Science of Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. CHU Tao's group from Zhejiang University, realized the fastest and miniaturized real-time quantum random number generator (QRNG) with the record-breaking output rate of 18.8 Gbps by combing a state-of-the-art photonic integrated chip with the optimized real-time post processing. The study was published in Applied Physics Letters on June 29. Random number exists in many fields such as information security and cryptology industries. Different from other random number generators, QRNG, as the key part in quantum communication system, embraces the characteristics ...

Prof. DU Jiangfeng, Prof. RONG Xing, and their colleagues from the Key Laboratory of Micromagnetic Resonance, University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS), set the most stringent laboratory constraint on the exotic spin- and velocity-dependent interaction at the micrometer scale. This study was published in Physical Review Letters. The search for dark matter, dark energy, and extra forces is important for the understanding of the existence of the matter that accounts for about a quarter of the universe, but little progress has been made. It is necessary to theoretically and experimentally find particles outside the Standard Model, a tradition ...