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The way a fish swims reveals a lot about its personality, say scientists

2021-02-23
The way a fish swims reveals a lot about its personality, say scientists Personality has been described in all sorts of animal species, from ants to apes. Some individuals are shy and sedentary, while others are bold and active. Now a new study published in Ecology and Evolution has revealed that the way a fish swims tells us a lot about its personality. This new research suggests experts can reliably measure animal personality simply from the way individual animals move, a type of micropersonality trait, and that the method could be used to help scientists understand about personality differences in wild animals. A team of biologists and mathematicians from Swansea University and the University of Essex filmed the movements of 15 three-spined stickleback ...

B cells continue to work against SARS-CoV-2 months after infection, but do not recognize mutant

2021-02-23
A new analysis of B cells and more than 1,000 different monoclonal antibodies from 8 patients with COVID-19 shows that, contrary to previous hypotheses, protective B cell responses to the SARS-CoV-2 spike protein remain stable and continue to evolve over a 5-month period, many months after the initial period of active viral replication. However, a large proportion of the neutralizing antibodies generated from these long-lasting B cells did not efficiently recognize various emerging SARS-CoV-2 variants from Brazil and South Africa. These results - from an academia-industry collaboration - will help inform the design of future COVID-19 vaccines that work to constrain viral evolution and stimulate ...

Scientists identify potential contributor to hyper immune responses in patients with severe COVID-19

2021-02-23
Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease. Their data support the ongoing investigation of anti-cytokine therapies that target this cell subset, called tissue-resident memory-like Th17 cells (Trm17). To date, the bulk of research on immune responses to COVID-19 has mainly focused on T cells in the blood, while the role of tissue-specific immune cells in the inflamed lung has remained unclear. Accumulating evidence suggests that one of the causes of ...

Mouse study shows bacteriophage therapy could fight drug-resistant Klebsiella pneumoniae

Mouse study shows bacteriophage therapy could fight drug-resistant Klebsiella pneumoniae
2021-02-23
WHAT: Using viruses instead of antibiotics to tame troublesome drug-resistant bacteria is a promising strategy, known as bacteriophage or "phage therapy." Scientists at the National Institutes of Health have used two different bacteriophage viruses individually and then together to successfully treat research mice infected with multidrug-resistant Klebsiella pneumoniae sequence type 258 (ST258). The bacterium K. pneumoniae ST258 is included on a CDC list of biggest antibiotic resistance threats in the United States. High rates of morbidity and mortality are associated with untreated K. pneumoniae infections. Phage therapy has been pursued for about a century, though conclusive research studies are rare and clinical results--from ...

'Walking' molecule superstructures could help create neurons for regenerative medicine

Walking molecule superstructures could help create neurons for regenerative medicine
2021-02-23
Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries. And imagine if they could "grow" these neurons in the laboratory from a patient's own cells using a synthetic, highly bioactive material that is suitable for 3D printing. By discovering a new printable biomaterial that can mimic properties of brain tissue, Northwestern University researchers are now closer to developing a platform capable of treating these conditions using regenerative medicine. A key ingredient to the discovery is the ability to control the self-assembly processes of molecules within the ...

Fibre-integrated, high-repetition-rate water window soft X-ray source

Fibre-integrated, high-repetition-rate water window soft X-ray source
2021-02-23
Bright, coherent soft X-ray radiation (SXR) is used in many scientific applications such as advanced absorption spectroscopy or lens-less imaging, and in fundamental research e.g. to produce extremely short isolated optical pulses. Therefore, the generation, control, and detection of this type of short-wavelength light is highly important in fields like fundamental atomic physics, solid-state physics, the semiconductor industry, material science and biology. To date, high photon flux in the soft X-ray spectral region is mostly delivered by large-scale facilities like synchrotrons or free electron lasers. An alternative is to use high-order harmonic generation (HHG) sources, which are currently driven by pulsed laser systems with ...

Artificial pancreas system upgraded with AI algorithm

Artificial pancreas system upgraded with AI algorithm
2021-02-23
Diabetes is on the rise worldwide. It is a permanent condition that requires care over a life time. To help manage it, an artificial pancreas system, which automatically measures blood sugar levels to infuse the appropriate amount of insulin into the blood, has now become smarter thanks to AI learning. A research team, led by Professor Sung-Min Park and Ph.D. candidate Seunghyun Lee and M.S. candidate Jiwon Kim of POSTECH's Department of Convergence IT Engineering and Electrical Engineering, has newly developed a reinforcement learning (RL) based AI algorithm that calculates the ...

Alzheimer Europe sets out recommendations to improve data sharing in dementia research

Alzheimer Europe sets out recommendations to improve data sharing in dementia research
2021-02-23
Luxembourg, 23 February 2021 - At an online European Parliament workshop hosted by Deirdre Clune MEP (Ireland), Alzheimer Europe launched a new report "Data Sharing in Dementia Research", which reviews recent changes in EU research policy and sets out recommendations to improve data sharing in dementia research. In this report, Alzheimer Europe evaluates the legal and policy landscapes that dementia researchers have had to navigate since the launch of Horizon 2020 in 2013. The report identifies key barriers and enablers for data sharing. It maps the Horizon 2020 dementia research portfolio, assessing the scale of EU investment in dementia research and the use of clinical ...

Saki monkeys get screen time for more control over their lives in captivity

2021-02-23
Helsinki, Finland--Technology helps humans maintain connections, get work done, and relax after a long day. How it can best improve the lives of animals, particularly those in captivity, however, has remained an open question. Scientists from Aalto University, in collaboration with Korkeasaari Zoo, have designed and built an on-demand video device for white-faced saki monkeys to activate as and when they like. While enrichment systems for zoo animals have been around for some time, very few offer animals the ability to choose when and how they use the device, even though choice and control are known to promote animal welfare. 'We were very much interested in how we can give animals control over their ...

Reimagined US-Middle East strategy would lean less on arms sales, more on dev't/governance

2021-02-23
U.S. policies in the Middle East are built on outdated "legacy" aid packages, massive arms sales and a disproportionate focus on the Iranian threat that fail to advance American interests - or help the region's people - and need to be rethought, according to a new RAND Corporation report. The United States devotes an overwhelming share of foreign military financing to just three countries - Israel, Egypt and Jordan, which received 81% of the $6 billion spent globally in 2019. If policymakers were to pursue an alternative strategy outlined by RAND researchers, ...

The magic angle of twisted graphene

The magic angle of twisted graphene
2021-02-23
Graphene, a two-dimensional material composed exclusively of carbon, has revealed extraordinary properties, including thermal and electrical conductivity, transparency, and flexibility. When combined, these properties become particularly interesting in the age of touch screens and flexible electronics! 'Unlike 3D materials, graphene has a height reduced to the ultimate dimension of the atom. It's therefore a carbon atom plane,' explains Prof. Jean-Christophe Charlier, a specialist in nanoscopic physics at the Institute of Condensed Matter and Nanosciences of UCLouvain. In a study published in Nature, the scientist and his team dissected the behaviour of electrons when two layers of graphene superimposed at an ...

Drifter or homebody? Study first to show where whitespotted eagle rays roam

2021-02-23
Its muscular body shape and large pectoral fins are perfect for long-distance travel, yet movement patterns of the whitespotted eagle ray (Aetobatus narinari) remain a mystery. Researchers from Florida Atlantic University's Harbor Branch Oceanographic Institute in collaboration with Mote Marine Laboratory & Aquarium, the University of Florida and the Florida Fish and Wildlife Conservation Commission, are the first to conduct a multiyear study examining large-scale movements of whitespotted eagle rays in United States waters. Between 2016 and 2018, scientists fitted 54 rays with acoustic transmitters ...

Largest comprehensive Middle East GWAS reveals Arab genetic risk factors

Largest comprehensive Middle East GWAS reveals Arab genetic risk factors
2021-02-23
Doha, Qatar - (February 23, 2021) - A group of researchers at Qatar Foundation have reported the first and largest genetic association study in the Middle East, that has been published online in Nature Communications - a leading a peer-reviewed, open access, scientific journal published by Nature Research. The study titled "Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits" highlights a vital piece of information wherein now there is a better understanding of the genetic risk factors that are specific to the Arab population, including those that are shared with other ethnicities. Qatar was among the first countries to launch its own large-scale, national genome project. Qatar Genome ...

New features of a gene defect that affects muzzle length and caudal vertebrae in dogs

New features of a gene defect that affects muzzle length and caudal vertebrae in dogs
2021-02-23
A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health. The variant was found in several Bulldog and Pit Bull type breeds, and it was shown to result in caudal vertebral anomalies and shortening of the muzzle. The DLV2 variant may also affect the development of the heart. Dog breeding is often focused on appearance. In some breeds, the ideal body shape is bulky, with a broad head and short muzzle, short legs and a very short and kinked tail, also known as a "screw tail". In a previous study in the United States, screw tail was linked to a variant in the DVL2 gene. The variant has become enriched ...

Sustainable but smartly: Tackling security and privacy issues in smart agriculture

2021-02-23
According to recent estimates, there will be roughly 10 billion people to feed in 2050. Agricultural production will need to increase by almost 56% to guarantee food security globally, without converting more land for agriculture (in line with environmental and climate targets). This unprecedented challenge has ushered in the era of "smart agriculture," which promises to revolutionize food production by combining agricultural techniques with information technology, automation, and artificial intelligence. This new era, called "Agriculture 4.0," could ensure sustainable food production for the entire world. However, as communities gradually embrace smart agriculture, it is important to understand how to manage the security and privacy risks associated with the integration of ...

CDDEP report highlights tremendous burden from infectious diseases in SEAR countries

2021-02-23
Washington, DC / New Delhi, India - Researchers at CDDEP, in collaboration with leading experts in the field, have produced the "Infectious Diseases in the South-East Asia Region" report, which examines cross-boundary challenges in communicable disease control in countries in the South-and South-East Asia region. The report emphasizes infectious diseases related to other sources of disease burden in the region and communicates overall trends in the health and economic burden they impose. Despite substantial progress in recent years, which has seen reductions in deaths from HIV and malaria and an increase ...

The invisible smallest particles matter for the air we breathe

The invisible smallest particles matter for the air we breathe
2021-02-23
Researchers of the University of Helsinki have resolved for the first time, how the ultrafine particles of atmosphere effect on the climate and health. Atmospheric air pollution kills more than 10,000 people every day. The biggest threat to human health has been assumed to be the mass accumulation of atmospheric particles with diameter smaller 2.5 μm: the higher the mass and loss of visibility, the bigger the threat. The researchers of the Institute for Atmospheric and Earth System Research (INAR) at the University of Helsinki together with collaborators in China discovered that if we want to solve the accumulation of the biggest particles, we need to start with the smallest. Until recent ...

Whale Sharks show remarkable capacity to recover from injuries

Whale Sharks show remarkable capacity to recover from injuries
2021-02-23
A new study has for the first time explored the rate at which the world's largest fish, the endangered whale shark, can recover from its injuries. The findings reveal that lacerations and abrasions, increasingly caused through collisions with boats, can heal in a matter of weeks and researchers found evidence of partially removed dorsal fins re-growing. This work, published in the journal Conservation Physiology, comes at a critical time for these large sharks, that can reach lengths of up to 18 metres. Other recent studies have shown that as their popularity within the wildlife tourism sector increases, so do interactions with humans and boat traffic. As a result, these ...

New therapeutic target for Huntington's treatment

New therapeutic target for Huntingtons treatment
2021-02-23
Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms. A new study conducted by the University of Barcelona has identified a type of ribonucleic acid (RNA) as a potential therapeutic target for the treatment of the disease. These are the small RNA, or sRNAs, molecules that do not code proteins but have important functions in the regulation of gene expression. According to the study, sRNAs would ...

Terahertz imaging of graphene paves the way to industrialisation

Terahertz imaging of graphene paves the way to industrialisation
2021-02-23
X-ray scans revolutionised medical treatments by allowing us to see inside humans without surgery. Similarly, terahertz spectroscopy penetrates graphene films allowing scientists to make detailed maps of their electrical quality, without damaging or contaminating the material. The Graphene Flagship brought together researchers from academia and industry to develop and mature this analytical technique, and now a novel measurement tool for graphene characterisation is ready. The effort was possible thanks to the collaborative environment enabled by the Graphene Flagship European consortium, with participation by scientists from Graphene Flagship partners DTU, Denmark, IIT, Italy, Aalto University, Finland, AIXTRON, UK, imec, Belgium, Graphenea, Spain, Warsaw ...

Seasonal variation in daylight influences brain function

Seasonal variation in daylight influences brain function
2021-02-23
Seasons have an impact on our emotions and social life. Negative emotions are more subdued in the summer, whereas seasonal affective disorder rates peak during the darker winter months. Opioids regulate both mood and sociability in the brain. In the study conducted at the Turku PET Centre, Finland, researchers compared how the length of daylight hours affected the opioid receptors in humans and rats. "In the study, we observed that the number of opioid receptors was dependent on the time of the year the brain was imaged. The changes were most prominent in the brain regions that control emotions and sociability. The changes in the opioid receptors caused by the variation in the amount of daylight could be an important factor in seasonal affective disorder," ...

New sensor paves way to low-cost sensitive methane measurements

New sensor paves way to low-cost sensitive methane measurements
2021-02-23
WASHINGTON -- Researchers have developed a new sensor that could allow practical and low-cost detection of low concentrations of methane gas. Measuring methane emissions and leaks is important to a variety of industries because the gas contributes to global warming and air pollution. "Agricultural and waste industries emit significant amounts of methane," said Mark Zondlo, leader of the Princeton University research team that developed the sensor. "Detecting methane leaks is also critical to the oil and gas industry for both environmental and economic reasons because natural gas is mainly composed of methane." In ...

Hormone helps prevent muscle loss in mice on high fat diets, USC study finds

2021-02-23
A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings present new possibilities for treating muscle-wasting conditions associated with age, obesity or cancer, according to scientists from the University of Southern California Leonard Davis School of Gerontology. The research, published this month in the American Journal of Physiology-Endocrinology and Metabolism, addresses the related problems of age and obesity-induced muscle loss, conditions which can lead to increased risk of falls, diabetes and other negative health impacts. It also adds to a growing number of findings describing beneficial effects of MOTS-c, ...

Don't focus on genetic diversity to save our species

Dont focus on genetic diversity to save our species
2021-02-23
Scientists at the University of Adelaide have challenged the common assumption that genetic diversity of a species is a key indicator of extinction risk. Published in the journal PNAS, the scientists demonstrate that there is no simple relationship between genetic diversity and species survival. But, Dr Joao Teixeira and Dr Christian Huber from the University of Adelaide's School of Biological Sciences conclude, the focus shouldn't be on genetic diversity anyway, it should be on habitat protection. "Nature is being destroyed by humans at a rate never seen before," says computational biologist Dr Huber. "We burn ...

More than 87,000 scientific papers on coronavirus since pandemic

2021-02-23
COLUMBUS, Ohio - Scientists from around the world have published more than 87,000 papers about coronavirus between the start of the COVID-19 pandemic and October 2020, a new analysis shows. Even given the importance of the pandemic, researchers were surprised by the huge number of studies and other papers that scientists produced on the subject in such a short time. "It is an astonishing number of publications - it may be unprecedented in the history of science," said Caroline Wagner, co-author of the study and associate professor in the John Glenn College of Public Affairs at The Ohio State University. "Nearly all of the scientific community around the world turned its attention to this one issue." Wagner conducted the analysis with Xiaojing Cai from Zhejiang University in ...
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