Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval. World's first 3D printed high tibial osteotomy (HTO) device and procedure developed at University of Bath given approval for UK trials Bespoke titanium alloy HTO implants that fit perfectly are designed to reduce discomfort for knee osteoarthritis patients Sophisticated 3D scanning aims to make surgery quicker and safer New TOKA process could make earlier intervention possible - saving patients decades of pain before surgery becomes viable Intro A ...

Many of us swing through gates every day -- points of entry and exit to a space like a garden, park or subway. Electronics have gates too. These control the flow of information from one place to another by means of an electrical signal. Unlike a garden gate, these gates require control of their opening and closing many times faster than the blink of an eye. Scientists at the U.S. Department of Energy's (DOE) Argonne National Laboratory and the University of Chicago's Pritzker School of Molecular Engineering have devised a unique means of achieving effective gate operation with a form of information processing called electromagnonics. Their pivotal discovery allows real-time control of information transfer between microwave photons and magnons. And it could result in a new generation ...

An important new study by researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory has yielded critical fresh insights into the lithium production process and how it relates to long-term environmental sustainability, particularly in the area of transportation with batteries and electric vehicles. The paper, "Energy, Greenhouse Gas, and Water Life Cycle Analysis of Lithium Carbonate and Lithium Hydroxide Monohydrate from Brine and Ore Resources and Their Use in Lithium Ion Battery Cathodes and Lithium Ion Batteries," in the journal ...

Prof. PAN Jianwei and Prof. ZHANG Jun from University of Science of Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. CHU Tao's group from Zhejiang University, realized the fastest and miniaturized real-time quantum random number generator (QRNG) with the record-breaking output rate of 18.8 Gbps by combing a state-of-the-art photonic integrated chip with the optimized real-time post processing. The study was published in Applied Physics Letters on June 29. Random number exists in many fields such as information security and cryptology industries. Different from other random number generators, QRNG, as the key part in quantum communication system, embraces the characteristics ...

Prof. DU Jiangfeng, Prof. RONG Xing, and their colleagues from the Key Laboratory of Micromagnetic Resonance, University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS), set the most stringent laboratory constraint on the exotic spin- and velocity-dependent interaction at the micrometer scale. This study was published in Physical Review Letters. The search for dark matter, dark energy, and extra forces is important for the understanding of the existence of the matter that accounts for about a quarter of the universe, but little progress has been made. It is necessary to theoretically and experimentally find particles outside the Standard Model, a tradition ...

Shells of tamarind, a tropical fruit consumed worldwide, are discarded during food production. As they are bulky, tamarind shells take up a considerable amount of space in landfills where they are disposed as agricultural waste. However, a team of international scientists led by Nanyang Technological University, Singapore (NTU Singapore) has found a way to deal with the problem. By processing the tamarind shells which are rich in carbon, the scientists converted the waste material into carbon nanosheets, which are a key component of supercapacitors - energy storage devices that are used in automobiles, buses, electric vehicles, trains, and elevators. The study reflects ...

Osaka, Japan - When things get too much, we're often advised to "take a load off," but when it comes to bone maintenance, doing the opposite can be a good thing. Researchers from Japan have discovered some key mechanisms of how physical load stimulates bone growth. In a study published July 13, 2021 at 11 a.m. ET in Cell Reports, researchers from the National Cerebral and Cardiovascular Center Research Institute have revealed that the expression of the peptide osteocrin (OSTN) is influenced by load - decreasing when load is reduced, and increasing when it is added. Bones and skeletal muscles are strengthened by the load associated with exercise, preventing bone and muscle atrophy, and maintaining bone and muscle strength is important for maintaining physical activity. ...

Researchers from Kumamoto University, Japan have found that a component derived from turmeric essential oil, aromatic turmerone (ar-turmerone), and its derivatives act directly on dopaminergic nerves to create a neuroprotective effect on tissue cultures of a Parkinson's disease model. This appears to be due to enhanced cellular antioxidant potency from the activation of Nrf2. The researchers believe that the ar-turmerone derivatives identified in this study can be used as new therapeutic agents for Parkinson's disease. Parkinson's disease is a neurodegenerative disease caused by the ...

When it comes to the medicinal and therapeutic properties of Cannabis sativa, an unsolved mystery is whether there exists an "entourage effect," whereby the pain-relieving effects of the plant as a whole are greater than any of its individual parts. New research from the University of Arizona Health Sciences has found evidence that favors the entourage effect theory and positions Cannabis terpenes, the part of the plant that provides flavor and aroma, as a promising new target for pain therapies that would require lower doses and produce fewer side effects. "A lot of people are taking cannabis and cannabinoids for pain," said lead researcher John Streicher, PhD, a member ...

An associate professor of marketing at The University of Texas at Arlington says digital avatars can replace a sales force and customer service employees at a fraction of the cost. In this context, avatars are typically computer-generated representations of people. UTA Associate Professor Fred Miao says they can fill the void in interactive assistance that a majority of shoppers says they want. "An Accenture survey of online shoppers shows that 62% never completed their purchases because there was no real-time customer service or support. That Accenture survey also shows that 90% of those shoppers wanted some sort of interactive assistance during the shopping process," said Miao, faculty fellow of the John Merrill Endowed Professorship ...

Sea-level rise threatens to produce more frequent and severe flooding in coastal regions and is expected to cause trillions of dollars in damages globally if no action is taken to mitigate the issue. However, communities trying to fight sea-level rise could inadvertently make flooding worse for their neighbors, according to a new study from researchers at The University of Texas at Arlington and the Stanford Natural Capital Project published in Proceedings of the National Academy of Sciences. Michelle Hummel, an assistant professor of civil engineering at UTA, was lead author of the report, which shows how seawalls constructed along the San Francisco Bay shoreline ...

UW researchers reveal new aspects of gum disease and body's protective response SEATTLE - A team led by University of Washington researchers has, for the first time, identified and classified how different people respond to the accumulation of dental plaque, the sticky biofilm that gathers on teeth. Their work, recently published in the journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), sheds important new light on why some people may be more prone to serious conditions that lead to tooth loss and other problems. Left unchecked, plaque buildup can induce gingivitis, or gum inflammation. Gingivitis, ...

CORVALLIS, Ore. - Oregon State University scientists are beginning to unravel the key microorganisms that contribute to the fermentation of kombucha, research that is already aiding large-scale kombucha producers in the fast-growing industry. Kombucha is a fermented tea drink that has been homebrewed around the world for centuries, but in recent years has become widely popular with a global market size expected to grow from $1.3 billion in 2019 to $8.1 billion by 2027, according to an industry report. Several large producers, including Humm and Brew Dr., are based in Oregon. Kombucha is produced by fermenting sugared tea using a symbiotic culture of bacteria and yeast, commonly referred to as SCOBY, and adding flavorings to enhance the taste. But ...

Vaccine skepticism among young adults may stall efforts to achieve herd immunity - a threshold in which approximately 80 percent of a population is vaccinated against the coronavirus. A study by UC San Francisco researchers found that about one in four unvaccinated people aged 18 to 25 said that they "probably will not" or "definitely will not" get the COVID-19 vaccination, despite the fact that this demographic has been found to be more likely than other age-groups to transmit coronavirus, jeopardizing the health of older unvaccinated adults and facilitating ...

Each fingertip has more than 3,000 touch receptors, which largely respond to pressure. Humans rely heavily on sensation in their fingertips when manipulating an object. The lack of this sensation presents a unique challenge for individuals with upper limb amputations. While there are several high-tech, dexterous prosthetics available today - they all lack the sensation of "touch." The absence of this sensory feedback results in objects inadvertently being dropped or crushed by a prosthetic hand. To enable a more natural feeling prosthetic hand interface, researchers from Florida Atlantic University's ...

New data on macaw movements gathered by the Texas A&M University College of Veterinary Medicine & Biomedical Sciences' (CVMBS) The Macaw Society has the potential to greatly improve conservation strategies for the scarlet macaw, as well as similar species of large parrots. While the overall conservation status of the scarlet macaw is listed as "least concern" by the International Union for Conservation of Nature, the species is declining across much of Central America and in other parts of its range in South America. The species also shares its habitat with numerous endangered species and influences the ecosystems in which ...

The concept of interoperability describes the ability of different systems to communicate. This is a major challenge in biomedical research, and in particular, in the field of personalised medicine, which is largely based on the compilation and analysis of numerous datasets. For instance, the COVID-19 pandemic has shown that even when the technical, legal and ethical constraints are lifted, the data remain difficult to analyse because of semantic ambiguities. Under the auspices of the Swiss Personalized Health Network (SPHN) and in close collaboration with representatives from all five Swiss university ...

Superconductivity is a physical phenomenon where the electrical resistance of a material drops to zero under a certain critical temperature. Bardeen-Cooper-Schrieffer (BCS) theory is a well-established explanation that describes superconductivity in most materials. It states that Cooper pairs of electrons are formed in the lattice under sufficiently low temperature and that BCS superconductivity arises from their condensation. While graphene itself is an excellent conductor of electricity, it does not exhibit BCS superconductivity due to the suppression of electron-phonon interactions. This is also the reason that most 'good' conductors such as gold and copper are 'bad' ...

The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against the SARS-CoV-2 virus. "mRNAs are a central component of all living things on our planet. Without them life as we know it would not function," says Elmar Wolf. Wolf is a professor for tumour system biology at the Department of Biochemistry and Molecular Biology at the University of Würzburg. With his research team, he has now deciphered new details about the formation of mRNA which provide novel insights into how a fundamental process inside cells works: the transcription. The team ...

A team of researchers, affiliated with UNIST has succeeded in developing a new optical microscope technology, capable of deeper imaging beyond the biological tissues. This breakthrough has been led by Professor Jung-Hoon Park and his research team in the Department of Biomedical Engineering at UNIST. Optical imaging technology has emerged as an essential research tool for biomedical studies due to its high resolution and good tomography capability. However, the limited penetration depth of the optical microscope makes it difficult to observe biological tissues of more than 100 μm thickness. This is because strong light scattering, caused by various components ...

New York, NY--July 13, 2021--The past decade has witnessed scandal after scandal over private images maliciously or accidentally made public. A new study from computer scientists at Columbia Engineering reveals what may be the first way to encrypt personal images on popular cloud photo services, such as those from Google, Apple, Flickr and others, all without requiring any changes to -- or trust in -- those services. Smartphones now make it easy for virtually everyone to snap photos, with market research firm InfoTrends estimating that people now take more than a trillion photos each year. The limited ...

A new study reveals the strategies that stop bandits from illegally fishing in Australian waters--but warns there is a cost to the region's poorer countries. Co-author Dr Brock Bergseth, from the ARC Centre of Excellence for Coral Reef Studies at James Cook University, said poachers are simply following the recurring history of human fishing: intensively fish and devastate local resources, then move further afield to--in these cases--fish illegally or poach in other countries' waters. "Millions of people rely on fish and seafood and when offered no alternative choice, will chose banditry and illegal fishing ...

A new method of DNA testing on cocoa beans could revolutionise the chocolate industry, offering consumers greater reassurance about the origins and ethics of their beloved confectionery, and giving the global cocoa industry a precision tool to help end slavery and child labour. Researchers from the University of Bath, University of the West of England, and Surrey Business School have proven a low-cost method which compares DNA in chocolate products to the cocoa when it is farmed. This means cocoa can be reliably traced back from an individual chocolate bar to the specific farms which cultivated the cocoa in it, a major advance on current fairtrading, certification and sustainability practices. "This has the potential to ...

What the fruit fly is to zoologists, the thale cress is to botanists. The widespread herb with the botanical name Arabidopsis thaliana serves them as a model organism from which knowledge can be gained for other plants. It is therefore extremely well researched - also genetically. For example, it is now known that the genetic material of Arabidopsis thaliana (its genome) comprises around 125 million base pairs. It's like having a Lego manual in front of you that is 125 million letters long and contains everything you need to know to build an Arabidopsis plant. Similar to humans, different Arabidopsis specimens are generally not genetically identical. If you were to compare the construction manual of all plants of this species, you would encounter differences in about 10 million places, ...

Dr. Iair Arcavi, a Tel Aviv University researcher at the Raymond and Beverly Sackler Faculty of Exact Sciences, participated in a study that discovered a new type of stellar explosion - an electron-capture supernova. While they have been theorized for 40 years, real-world examples have been elusive. Such supernovas arise from the explosions of stars 8-9 times the mass of the sun. The discovery also sheds new light on the thousand-year mystery of the supernova from A.D. 1054 that was seen by ancient astronomers, before eventually becoming the Crab Nebula, that we know today. A supernova is the explosion of a star following a ...