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USPSTF reaffirms recommendation of screening for high blood pressure in adults

2021-04-27
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) reaffirms its earlier recommendation of screening for high blood pressure in adults 18 years or older with office blood pressure measurement and obtaining measurements outside of the clinical setting for confirming a diagnosis of high blood pressure before starting treatment. Hypertension affects approximately 45% of adults in the United States and is a major contributing risk factor for heart failure, heart attack, stroke and chronic kidney disease. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation reaffirms its 2015 statement. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2021.4987) Editor's ...

Association of facial paralysis with mRNA COVID-19 vaccines

2021-04-27
What The Study Did: This analysis uses the World Health Organization pharmacovigilance database to explore the potential safety signal of facial paralysis after COVID-19 vaccination. When compared with other viral vaccines, mRNA COVID-19 vaccines did not display a signal of facial paralysis. Authors: Charles Khouri, Pharm.D., of the University Grenoble Alpes and Grenoble Alpes University Hospital in Grenoble, France, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2021.2219) Editor's Note: Please see the article for additional information, including ...

Fair climate policy could help reduce extreme poverty

2021-04-27
Ambitious climate policies could help to reduce extreme poverty in developing countries. This is the result of a new study by scientists of the Potsdam Institute for Climate Impact Research (PIK) - a result that is in contrast to wide-spread assumptions that climate change mitigation comes with a trade-off for poverty reduction. To turn climate policies and poverty reduction into a win-win situation for planet and people, a progressive redistribution of emission pricing revenues and a fair international burden sharing are key. "Climate policies safeguard people from climate change impacts like extreme weather risks or crop failures. Yet they can also imply increased energy and food prices," says Bjoern Soergel from PIK, lead-author of the study. "This could result in an additional ...

California campaign lowers statewide C-section rate, Stanford-led study finds

2021-04-27
A four-year effort has reduced the rate of cesarean sections for low-risk, first-time mothers in California, according to a study led by researchers at the Stanford University School of Medicine and the California Maternal Quality Care Collaborative. The study will be published April 27 in the Journal of the American Medical Association. Several coordinated initiatives to reduce C-sections took place across the state during the 2015-19 study period, including messaging to all hospitals from state agencies and health plans, annual public reporting of hospitals' C-section rates, and a quality improvement program targeting hospitals with the highest rates. The study examined the collective effect of these projects, which have led California to become the first state in the country ...

Solar-powered desalination unit shows great promise

Solar-powered desalination unit shows great promise
2021-04-27
WASHINGTON, April 27, 2021 -- Despite the vast amount of water on Earth, most of it is nonpotable seawater. Freshwater accounts for only about 2.5% of the total, so much of the world experiences serious water shortages. In AIP Advances, by AIP Publishing, scientists in China report the development of a highly efficient desalination device powered by solar energy. The device consists of a titanium-containing layer, TiNO, or titanium nitride oxide, capable of absorbing solar energy. The TiNO is deposited on a special type of paper and foam that allows the solar absorber ...

Polymer-based coatings on metallic implants improve bone-implant integration

Polymer-based coatings on metallic implants improve bone-implant integration
2021-04-27
WASHINGTON, April 27, 2021 -- Traffic accidents, tumor resections, and congenital diseases can cause significant trauma, which can lead to large bone deformations and/or bone loss. Although bone has some capacity to regenerate, large bone defects cannot be healed without major medical procedures. In these situations, metallic implants are widely used, but the bioinertness of such implants poses a major challenge in bone tissue engineering. Bioinert metal implants lack bone integration, loosen over time, and may lead to adverse reactions around the area in which ...

Salk scientists reveal how brain cells in Alzheimer's go awry, lose their identity

Salk scientists reveal how brain cells in Alzheimers go awry, lose their identity
2021-04-27
LA JOLLA--(April 27, 2021) Despite the prevalence of Alzheimer's, there are still no treatments, in part because it has been challenging to study how the disease develops. Now, scientists at the Salk Institute have uncovered new insights into what goes awry during Alzheimer's by growing neurons that resemble--more accurately than ever before--brain cells in older patients. And like patients themselves, the afflicted neurons appear to lose their cellular identity. The findings, published April 27, 2021, in the journal Cell Stem Cell, showed that these brain cells are characterized by markers of stress as well as changes in which the cells become less specialized. ...

Researchers show new holistic approach to genetics and plant breeding

Researchers show new holistic approach to genetics and plant breeding
2021-04-27
The research was conducted at the Department of Food Science at the University of Copenhagen (UCPH FOOD) with professor emeritus Lars Munck as coordinator and builds on earlier work since 1963 at Svaloef Plant Breeding Institute and the Carlsberg Laboratory. A complete picture of the organism The research shows how, with the help of a fast, non-destructive and green analysis method, near-infrared spectroscopy (NIRS), we can obtain a global overview that mirrors how the entire chemical composition of nutrients in a barley grain is changed, for example, by a mutation in a single gene. This is in contrast to current ...

Researchers find mechanism underlying muscle weakness in Becker disease

2021-04-27
Muscle weakness in patients with Becker disease is caused by unusual electrical activity in muscle fibres termed 'plateau potentials' that make them temporarily inactive, says a study published today in eLife. An understanding of these mechanisms and the ion channels involved may help the search for more effective therapies for weakness in Becker disease and other muscle diseases, and help understand how electrical activity is regulated in muscles. Recessive myotonia congenita, also known as Becker disease, is a heritable skeletal muscle disease caused by mutated chloride ...

New 2D superconductor forms at higher temperatures than ever before

New 2D superconductor forms at higher temperatures than ever before
2021-04-27
New interfacial superconductor has novel properties that raise new fundamental questions and might be useful for quantum information processing or quantum sensing. Interfaces in solids form the basis for much of modern technology. For example, transistors found in all our electronic devices work by controlling the electrons at interfaces of semiconductors. More broadly, the interface between any two materials can have unique properties that are dramatically different from those found within either material separately, setting the stage for new discoveries. Like semiconductors, superconducting materials have many important implications for technology, from magnets for MRIs to speeding up electrical connections or perhaps making possible quantum technology. The ...

Exploiting non-line-of-sight paths for terahertz signals in wireless communications

Exploiting non-line-of-sight paths for terahertz signals in wireless communications
2021-04-27
WASHINGTON, April 27, 2021 -- If a base station in a local area network tries to use a directional beam to transmit a signal to a user trying to connect to the network -- instead of using a wide area network broadcast, as base stations commonly do -- how does it know which direction to send the beam? Researchers from Rice University and Brown University developed a link discovery method in 2020 using terahertz radiation, with high-frequency waves above 100 gigahertz. For this work, they deferred the question of what would happen if a wall or other reflector nearby creates a non-line-of-sight (NLOS) path from the base station to the receiver and focused on the simpler situation where ...

Few young adult men have gotten the HPV vaccine, study finds

Few young adult men have gotten the HPV vaccine, study finds
2021-04-27
The COVID-19 vaccine isn't having any trouble attracting suitors. But there's another, older model that's been mostly ignored by the young men of America: the HPV vaccine. Using data from the 2010-2018 National Health Interview Surveys, Michigan Medicine researchers found that just 16% of men who were 18 to 21 years old had received at least one dose of the HPV vaccine at any age. In comparison, 42% of women in the same age bracket had gotten at least one shot of the vaccine. The CDC's Advisory Committee on Immunization Practices recommends two doses of the vaccine ...

Stem cell therapy shows potential to heal intestinal disease in premature infants

2021-04-27
WINSTON-SALEM, NC - April 27, 2021 -- An intestinal bowel disease that affects up to 10 percent of premature infants at a very vulnerable and developmentally crucial time can lead to serious infection and death. Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) are tackling the disease with a human placental-derived stem cell (hPSC) therapy strategy that is showing promising results. Necrotizing enterocolitis is a life-threatening intestinal disease that is a leading cause of mortality in premature infants and treatment options remain elusive. The ...

NYU Abu Dhabi researchers design simulator to help stop the spread of 'fake news'

NYU Abu Dhabi researchers design simulator to help stop the spread of fake news
2021-04-27
Abu Dhabi, UAE, April 27, 2021: As people around the world increasingly get their news from social media, online misinformation has emerged as an area of great concern. To improve news literacy and reduce the spread of misinformation, NYUAD Center for Cybersecurity researcher and lead author Nicholas Micallef is part of a team that designed Fakey, a game that emulates a social media news feed and prompts players to use available signals to recognize and scrutinize suspicious content and focus on credible information. Players can share, like, or fact-check individual articles. In a new study, Fakey: A Game Intervention to Improve News Literacy on Social Media published in the ACM Digital Library, Micallef and his colleagues ...

Household aerosols now release more harmful smog chemicals than all UK vehicles

2021-04-27
Aerosol products used in the home now emit more harmful volatile organic compound (VOC) air pollution than all the vehicles in the UK, new research shows. A new study by the University of York and the National Centre for Atmospheric Science reveals that the picture is damaging globally with the world's population now using huge numbers of disposable aerosols - more than 25 billion cans per year. This is estimated to lead to the release of more than 1.3 million tonnes of VOC air pollution each year, and could rise to 2.2 million tonnes by 2050. The chemicals now used in compressed aerosols ...

Exposure to high heat neutralizes SARS-CoV-2 in less than one second

Exposure to high heat neutralizes SARS-CoV-2 in less than one second
2021-04-27
Arum Han, professor in the Department of Electrical and Computer Engineering at Texas A&M University, and his collaborators have designed an experimental system that shows exposure of SARS-CoV-2 to a very high temperature, even if applied for less than a second, can be sufficient to neutralize the virus so that it can no longer infect another human host. Applying heat to neutralize COVID-19 has been demonstrated before, but in previous studies temperatures were applied from anywhere from one to 20 minutes. This length of time is not a practical solution, ...

Don't go fracking my heart

2021-04-27
The Marcellus Formation straddles the New York State and Pennsylvania border, a region that shares similar geography and population demographics. However, on one side of the state line unconventional natural gas development - or fracking - is banned, while on the other side it represents a multi-billion dollar industry. New research takes advantage of this 'natural experiment' to examine the health impacts of fracking and found that people who live in areas with a high concentration of wells are at higher risk for heart attacks. "Fracking is associated ...

Exercise reduces risk of airway disease

2021-04-27
OAK BROOK, Ill. - Exercise appears to reduce the long-term risk of bronchiectasis, a potentially serious disease of the airways, according to a study published in the journal Radiology. Bronchiectasis is characterized by repeated cycles of inflammation and exacerbations that damage the airways, leaving them enlarged, scarred and less effective at clearing mucus. This creates an environment ripe for infections. Risk increases with age and the presence of underlying conditions like cystic fibrosis. There is no cure. Computed tomography (CT) is used to confirm or rule out the disease in patients with symptoms like shortness of breath ...

Hepatitis C drugs boost Remdesivir's antiviral activity against COVID-19

Hepatitis C drugs boost Remdesivirs antiviral activity against COVID-19
2021-04-27
Remdesivir is currently the only antiviral drug approved in the U.S. for treating COVID-19 patients. In a paper published this week in Cell Reports, researchers from The University of Texas at Austin, Rensselaer Polytechnic Institute (RPI) and the Icahn School of Medicine at Mount Sinai showed that four drugs used to treat hepatitis C render remdesivir 10 times better at inhibiting the coronavirus in cell cultures. These results indicate that a mixture containing remdesivir and a repurposed hepatitis C virus (HCV) drug could potentially function as a combination antiviral therapy for SARS-CoV-2. Such an antiviral could provide an immediate treatment for unvaccinated people who become infected and for vaccinated people whose immunity has waned. Because these hepatitis drugs are already ...

Geographies of death: Study maps COVID-19 health disparities in Greater Santiago

Geographies of death: Study maps COVID-19 health disparities in Greater Santiago
2021-04-27
CHAMPAIGN, Ill. -- People up to age 40 living in economically depressed municipalities in the Greater Santiago, Chile, metropolitan area were three times more likely to die as a result of the infection than their counterparts in wealthier areas, researchers report in the journal Science. People ages 41-80 in low socioeconomic-status municipalities also suffered more from the pandemic than their peers in more affluent areas, the team found. The study used new methods to analyze COVID-19 death counts, reported cases, testing rates and delays in testing results across location, time ...

New method preserves viable fruit fly embryos in liquid nitrogen

2021-04-27
Cryopreservation, or the long-term storage of biomaterials at ultralow temperatures, has been used across cell types and species. However, until now, the practical cryopreservation of the fruit fly (Drosophila melanogaster) -- which is crucial to genetics research and critical to scientific breakthroughs benefiting human health -- has not been available. "To keep alive the ever-increasing number of fruit flies with unique genotypes that aid in these breakthroughs, some 160,000 different flies, laboratories and stock centers engage in the costly and frequent transfer of adults to fresh food, risking contamination and genetic drift," said Li Zhan, a postdoctoral associate with the University of Minnesota College of Science and Engineering and the Center for Advanced ...

UMD studies mangrove genetic diversity in Africa to conserve centers of biodiversity

UMD studies mangrove genetic diversity in Africa to conserve centers of biodiversity
2021-04-27
In collaboration with researchers at the Vrije Universiteit Brussel, a University of Maryland (UMD) postdoctoral researcher recently co-published a large-scale study examining the genetic diversity of mangroves over more than 1,800 miles of coastline in the Western Indian Ocean, including Eastern Africa and several islands. While the mangroves of Asia, Australia, and the Americas have been more extensively studied, little work has been done classifying and highlighting genetic diversity in African mangrove populations for conservation. Similar to other wetlands, mangrove ...

Researchers find breastfeeding linked to higher neurocognitive testing scores

2021-04-27
New research finds that children who were breastfed scored higher on neurocognitive tests. Researchers in the Del Monte Institute for Neuroscience at the University of Rochester Medical Center (URMC) analyzed thousands of cognitive tests taken by nine and ten-year-olds whose mothers reported they were breastfed, and compared those results to scores of children who were not. "Our findings suggest that any amount of breastfeeding has a positive cognitive impact, even after just a few months." Daniel Adan Lopez, Ph.D. candidate in the Epidemiology program who is first author on the study recently ...

Women's football in Japan had a rich history before WWII

Womens football in Japan had a rich history before WWII
2021-04-27
A team of scientists has found that women's football was common across Japan between the Meiji restoration and the start of the Second World War. In the process, they also uncovered the oldest known photograph of women playing football in Japan, from 1916. The history of men's football in Japan is well documented. In particular, the introduction of association football into Japan in the late 19th and 20th centuries has been extensively investigated. The same degree of attention had not been paid to women's football. A team of researchers from six institutions, including Associate Professor Yoshihiro ...

Nature provides inspiration for breakthrough in self-regulating materials

Nature provides inspiration for breakthrough in self-regulating materials
2021-04-27
AMHERST Mass. - Scientists have long sought to invent materials that can respond to the external world in predictable, self-regulating ways. Now, new research conducted at the University of Massachusetts Amherst and appearing in the Proceedings of the National Academy of Sciences brings us one step closer to that goal. For their inspiration, the scientists looked to nature. Lampreys swimming, horses walking, and insects flying: each of these behaviors is made possible by a network of oscillators--mechanisms that produce a repetitive motion, such as wriggling a tail, taking a stride, or flapping a wing. What's more, these natural oscillators can respond to their environment in predictable ways. In ...
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