Disabilities were underreported in clinical trial data and commonly used as a basis for exclusion from trial participation in an analysis of 80 recent trials involving cardiovascular outcomes, according to a study being presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology. Reports estimate that over half of people with heart disease have one or more disabilities related to cognition, mobility, vision, independent living, self-care or hearing as defined by the Centers for Disease Control and Prevention (CDC). However, the new study found that 38% of clinical ...

Experiencing lasting symptoms months after catching COVID-19, also known as long COVID, was found to more than double a person’s likelihood of developing cardiovascular issues, according to a study being presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology. The study—a systematic literature review and meta-analysis of 11 major studies involving a total of 5.8 million people—represents the most comprehensive effort to date to examine cardiovascular complications from long COVID. Estimates of the number of people affected by long COVID vary substantially, but recent surveys suggest about 1 in 7 ...

Men who never married were more than twice as likely to die within about five years after a heart failure diagnosis compared with women of any marital status or men who were previously married, according to a study presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology. The study offers new evidence that a person’s gender and marital status can influence their heart disease risk and prognosis. Heart failure, when the heart muscle becomes too weak ...

Places with higher rates of economic connectedness—linkages between people of lower and higher socioeconomic status as indicated by Facebook friendships—had significantly lower rates of premature death related to heart disease, according to a study presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology. Previous studies have shown that poverty or low socioeconomic status increases a person’s risk of heart disease and premature death. This new study is ...

For people with heart failure, restricting dietary sodium intake to levels below the standard recommended maximum of about 2.3 grams per day does not bring additional benefits and may increase the risk of death, according to findings from nine randomized controlled trials in a new meta-analysis presented at the American College of Cardiology’s Annual Scientific Session Together With the World Congress of Cardiology. Heart failure, in which the heart muscle becomes too weak or stiff to pump blood effectively, is a chronic condition affecting over 6 million adults in the U.S. Physicians recommend a low-sodium diet to reduce blood pressure and avoid common symptoms ...

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient’s brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher. Cerebral small vessel disease, a common disease marked by damage to the cells lining the blood vessels in the brain, is a major driver of cognitive problems and dementia in older adults. However, it can be difficult for doctors to determine whether a patient’s cognitive impairments stem predominately from Alzheimer’s disease or vascular problems, the two most common causes of ...

The university world is international, but grapples with difficulties in integrating students from different countries. New research from Chalmers University of Technology, Sweden, points to a method that both reduces academic and social gaps and increases well-being. The recipe for success is to work in pairs – as chosen by the teacher. There is plenty of research indicating that integration is a decisive factor for a successful student life, both socially and academically, for the individual and for the university. Students who are involved in activities and feel connected to their fellow students can get higher grades and are more likely to continue ...

PULLMAN, Wash. -- An air filter made out of corn protein instead of petroleum products can concurrently capture small particulates as well as toxic chemicals like formaldehyde that current air filters can’t. The research could lead to better air purifiers, particularly in regions of the world that suffer from very poor air quality. Washington State University engineers report on the design and tests of materials for this bio-based filter in the journal Separation and Purification Technology. “Particulate matter is not that challenging to filter but to simultaneously capture various kinds of chemical ...

Patients with hypertension paired with a community health worker (CHW) through their primary care practice were more than three and a half times as likely to achieve blood pressure control within six months compared to patients who were not. New research, led by researchers at NYU Grossman School of Medicine, suggest that similar CHW inventions could help other underserved, immigrant communities experiencing similar disparities. Published online today in the journal Circulation: Cardiovascular Quality and Outcomes, the findings focus on community health workers (CHWs), lay members of a community who usually share ethnicity, language, income level, and/or life experiences with the people ...

Dr. Omar Abdul-Rahman, a leading specialist in pediatric genetic medicine, has been named chief of the Division of Medical Genetics in the Department of Pediatrics at Weill Cornell Medicine and NewYork-Presbyterian Komansky Children’s Hospital, effective March 1. The Division of Medical Genetics provides inpatient and outpatient consultation and medical care for children and adolescents with common and rare genetic conditions, including screening and counseling for inherited disease risk during pregnancy. Dr. Abdul-Rahman, who was recruited ...

Bottom Line: Among cancer patients who developed cardiotoxicity after treatment with immune checkpoint inhibitor (ICI) therapy, those treated with abatacept (Orencia), ruxolitinib, and/or mechanical ventilation as needed had a significantly lower mortality rate than those treated with standard-of-care corticosteroids. Journal in Which the Study was Published: Cancer Discovery, a journal of the American Association for Cancer Research (AACR) Author: Joe-Elie Salem, MD, PhD, a professor at Sorbonne Université, and executive assistant director of one of France’s Clinical Investigation Centers focused on cardio-metabolism Background: Immune checkpoint inhibitors comprise ...

WASHINGTON, D.C.—The U.S. Department of Energy (DOE) today announced awards totaling more than $68 million that will go to 53 small businesses that are solving scientific problems. Projects include developing tools for climate research and advanced materials and technologies for clean energy conversion. Understanding the climate and the ability to convert and store energy are instrumental to meeting President Biden’s goal of a completely clean electrical grid by 2035 and net-zero greenhouse-gas emissions ...

The ongoing opioid epidemic continues to take a heavy toll on American communities, with more than 80,000 opioid-related deaths reported in 2021, according to the National Institutes of Health. Despite the severity of this issue, the neurological mechanisms underlying opioid addiction, withdrawal and relapse are not fully understood. A study recently published in Cell Reports sheds light on the subject. Jun Wang, associate professor in the Department of Neuroscience and Experimental Therapeutics at the Texas A&M University School of Medicine, and members ...

(SEATTLE, Wednesday 22 February 2023) Two newer simplified treatment options are at least as effective as current approaches, according to the results of a world-first international clinical trial into second-line HIV therapy led by the Kirby Institute at UNSW Sydney and presented today at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle. Second-line treatment is the name given to the range of treatment options available to a person for whom the first HIV treatment offered to them does not work. Worldwide, this is about 10% of people ...

Many owners of electric cars have wished for a battery pack that could power their vehicle for more than a thousand miles on a single charge. Researchers at the Illinois Institute of Technology (IIT) and U.S. Department of Energy’s (DOE) Argonne National Laboratory have developed a lithium-air battery that could make that dream a reality. The team’s new battery design could also one day power domestic airplanes and long-haul trucks. The main new component in this lithium-air battery is a solid electrolyte instead of the usual liquid variety. Batteries with solid electrolytes ...

VIDEOS: Interviews, B-Roll https://www.dropbox.com/scl/fo/b1tpiamgunp5ekymyxaks/h?dl=0&rlkey=zk15bee6kru69ebryxaha0g3j YouTube Video. Unlisted & only viewable w/ link until embargo lifts. https://youtu.be/Ceg7R3sw7Qs   Patients with Parkinson’s disease achieved a significant improvement in their tremors, mobility, and other physical symptoms after having a minimally invasive procedure involving focused ultrasound, according to a new study today published in the New England Journal of Medicine. The clinical trial was led by researchers at the ...

A University of Texas at Arlington bioengineering professor is leading a state-funded project that will try to identify what T-cells are detecting in cancerous cells to better craft a personalized cancer immunotherapy. George Alexandrakis received a $250,000 Cancer Prevention and Research Institute of Texas (CPRIT) grant titled “Ultrasensitive Nanosensor-Based Detection of Tumor Immunogenic Peptides to Enable Personalized Cancer Immunotherapy.” “One of the challenges with cancer is that it is so variable. It changes all the time and is different in all people,” Alexandrakis said. ...

Patients experiences of health conditions are slowly being integrated into healthcare AI studies, a review of 25 years of studies has found. In a new paper published in Lancet Digital Health along with an associated opinion piece, experts from the University of Birmingham and University Hospitals Birmingham have looked at more than 600 interventional studies on AI healthcare technologies. While the team, funded by the National Institute for Health and Care Research (NIHR), found that only 24% of studies have a patient reported outcome element included in their study, there has been an increase in the number in recent years with 2021 and 2022 seeing nearly two thirds of all studies ...

Imperial experts are calling for more to be done to limit the potentially harmful impact of toxic tyre particles on health and the environment.  The researchers, from Imperial College London’s Transition to Zero Pollution initiative, warn that even though electric vehicles remove the problem of fuel emissions, we will continue to have a problem with particulate matter because of tyre wear.   Six million tonnes of tyre wear particles are released globally each year, and in London alone, 2.6 million vehicles emit around nine thousand tonnes of tyre wear particles annually.   Despite this, research on the environmental ...

Recommendations from research published today on the diagnosis and treatment of spinal cord damage caused by nitrous oxide abuse have been simultaneously adopted as official clinical practice guidelines by the Association of British Neurologists. The unprecedented speed in translating research into practice is necessary as medical cases of nitrous oxide abuse surge in parallel with increased use of what is now the second most popular recreational drug among young people in the UK. Recreational use of nitrous oxide (N2O - also known as laughing gas) ...

Leesburg, VA, February 23, 2023—According to an accepted manuscript published in ARRS’ American Journal of Roentgenology (AJR), certain reasons for AI tool failure relating to technical factors may be largely preventable through proper acquisition and reconstruction protocols. “The automated AI body composition tools had high technical adequacy rates in a heterogeneous sample of external CT examinations, supporting the tools’ generalizability and potential for broad use,” concluded head researcher B. Dustin Pooler, MD, from the University of ...

New predatory fish species which lived about 360 million years ago may have grown to over 2.5m long, according to analysis of South African fossils ### Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0281333 Article Title: A high latitude Gondwanan species of the Late Devonian tristichopterid Hyneria (Osteichthyes: Sarcopterygii) Author Countries: South Africa, Sweden Funding: PEA: Wallenberg Scholarship (not numbered), from the Knut & Alice Wallenberg Foundation. https://kaw.wallenberg.org PEA: ERC Advanced ...

Influence of US weather conditions on tornado trends since 1980 explored by new model ### Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0281312 Article Title: Long term temporal trends in synoptic-scale weather conditions favoring significant tornado occurrence over the central United States Author Countries: USA Funding: The authors received no specific funding for this work. END ...

Cash transfers in LMICs may help alleviate depression and anxiety symptoms - especially if such transfers are unconditional ### Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0281283 Article Title: Do cash transfers alleviate common mental disorders in low- and middle-income countries? A systematic review and meta-analysis Author Countries: UK, Germany Funding: JS was supported by the Joachim Herz Foundation (https://www.joachim-herz-stiftung.de/en/). AR received funding from the Wellcome Trust (220206/Z/20/Z, ...

Two high status brothers buried in a Bronze Age tomb in Israel were severely ill but apparently had access to rare treatments including trephination, according to a study published February 22, 2023 in the open-access journal PLOS ONE by Rachel Kalisher of Brown University, Rhode Island, and colleagues. In this study, authors examined the remains of two individuals buried in a tomb beneath an elite residence in the archaeological site of Tel Megiddo in Israel. The tomb dates to the Late Bronze Age (around 1550-1450 BC), and DNA testing suggests the buried individuals are brothers. Both skeletons show evidence of disease, providing an opportunity ...