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Science 2021-07-22

Inheriting mother's friends key to hyena success

EAST LANSING, Mich. - In the wild, inheriting advantageous physical traits may be the difference between a long life and a short one. But for the spotted hyena, another kind of inheritance, one that has nothing to do with genetics, turns out to be extremely important for health and longevity -- social networks inherited from their mothers. A new study, based on 27 years of observational data from Michigan State University Distinguished Professor Kay Holekamp, expands a previously established theoretical model of spotted hyena social networking to show how these networks emerge, how long they last and how they affect a hyena's life trajectory. The paper is featured as the front cover for the journal Science. "There ...
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Long COVID and severe COVID-19 infections associated with Epstein-Barr virus reactivation
Medicine 2021-07-22

Long COVID and severe COVID-19 infections associated with Epstein-Barr virus reactivation

Two recently published studies available on the National Institutes of Health (NIH) website indicate Epstein-Barr virus (EBV) reactivation may play a role both in the development of long COVID symptoms, as well as severe COVID-19 cases. The first evidence linking EBV reactivation to long COVID symptoms was discovered by Gold et al. (2021) and published in Pathogens. This study can be viewed on the NIH website here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233978/ "We ran Epstein-Barr virus serological tests on COVID-19 patients at least 90 days after testing positive for SARS-CoV-2 infection, comparing EBV ...
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Medicine 2021-07-21

Self-collected saliva and courier service -- A feasible diagnostic strategy for COVID-19

Alexandria, Va., USA - Walter Siqueira, University of Saskatchewan, Saskatoon, Canada, presented the poster "Self-collected Saliva and Courier Service - A Feasible Diagnostic Strategy for COVID-19" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021. Saliva has been proposed as a convenient and cost-effective biofluid for diagnostic purposes and in vitro studies have shown that the addition of stabilizers to saliva preserves it for up to 7-10 days at room temperature, but its translational application ...
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How does the structure of cytolysins influence their activity?
Science 2021-07-21

How does the structure of cytolysins influence their activity?

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so. "Your chances of dying increase by 5-fold when you get infected by E. faecalis that can make cytolysin compared to those that cannot," said Wilfred van der Donk (MMG), a professor of chemistry and investigator of the Howard Hughes Medical Institute. "Cytolysin is an important molecule and it has been known since the 1930s, our lab determined the ...
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Technology 2021-07-21

New simulator helps robots sharpen their cutting skills

Researchers from the University of Southern California (USC) Department of Computer Science and NVIDIA have unveiled a new simulator for robotic cutting that can accurately reproduce the forces acting on a knife as it slices through common foodstuffs, such as fruit and vegetables. The system could also simulate cutting through human tissue, offering potential applications in surgical robotics. The paper was presented at the Robotics: Science and Systems (RSS) Conference 2021 on July 16, where it received the Best Student Paper Award. In the past, researchers have had trouble creating intelligent ...
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New quantum research gives insights into how quantum light can be mastered
Technology 2021-07-21

New quantum research gives insights into how quantum light can be mastered

Los Alamos, N.M., July 21, 2021--A team of scientists at Los Alamos National Laboratory propose that modulated quantum metasurfaces can control all properties of photonic qubits, a breakthrough that could impact the fields of quantum information, communications, sensing and imaging, as well as energy and momentum harvesting. The results of their study were released yesterday in the journal Physical Review Letters, published by the American Physical Society. "People have studied classical metasurfaces for a long time," says Diego Dalvit, who works in the Condensed Matter and Complex Systems group at the Laboratory's Theoretical Division. "But we came up with this new idea, which was to modulate in time and space the optical properties of ...
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Technology 2021-07-21

New framework applies machine learning to atomistic modeling

Northwestern University researchers have developed a new framework using machine learning that improves the accuracy of interatomic potentials -- the guiding rules describing how atoms interact -- in new materials design. The findings could lead to more accurate predictions of how new materials transfer heat, deform, and fail at the atomic scale. Designing new nanomaterials is an important aspect of developing next-generation devices used in electronics, sensors, energy harvesting and storage, optical detectors, and structural materials. To design these materials, researchers create interatomic potentials through atomistic modeling, a computational approach that predicts how these materials behave by accounting for their ...
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A history of African dust
Science 2021-07-21

A history of African dust

In a recently published paper, a research team, led by University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science Professor Emeritus Joseph M. Prospero, chronicles the history of African dust transport, including three independent "first" discoveries of African dust in the Caribbean Basin in the 1950s and 1960s. Every year, mineral-rich dust from North Africa's Sahara Desert is lifted into the atmosphere by winds and carried on a 5,000-mile journey across the North Atlantic to the Americas. African dust contains iron, phosphorus and other important nutrients that are essential for life in marine and terrestrial ...
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Science 2021-07-21

How a unique sponge 'goes with the flow' could improve man-made structures

BROOKLYN, New York, Weekday, Month xx, 2021 - The remarkable structural properties of the Venus' flower basket sponge (E. aspergillum) might seem fathoms removed from human-engineered structures. However, insights into how the organism's latticework of holes and ridges influences the hydrodynamics of seawater in its vicinity could lead to advanced designs for buildings, bridges, marine vehicles and aircraft, and anything that must respond safely to forces imposed by the flow of air or water. While past research has investigated the structure of the sponge, there have been few studies of the hydrodynamic fields surrounding and penetrating the organism, and whether, besides improving its mechanical ...
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Medicine 2021-07-21

Dynamic heart model mimics hemodynamic loads, advances engineered heart tissue technology

Efforts to understand cardiac disease progression and develop therapeutic tissues that can repair the human heart are just a few areas of focus for the Feinberg research group at Carnegie Mellon University. The group's latest dynamic model, created in partnership with collaborators in the Netherlands, mimics physiologic loads on engineering heart muscle tissues, yielding an unprecedented view of how genetics and mechanical forces contribute to heart muscle function. "Our lab has been working for a long time on engineering and building human heart muscle tissue, so we can better ...
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New study confirms relationship between toxic pollution, climate risks to human health
Medicine 2021-07-21

New study confirms relationship between toxic pollution, climate risks to human health

For more than 30 years, scientists on the U.N.'s Intergovernmental Panel on Climate Change have focused on human-induced climate change. Their fifth assessment report led to the Paris Agreement in 2015 and, shortly after, a special report on the danger of global warming exceeding 1.5 degrees Celsius above pre-industrial levels. The Nobel Prize-winning team stressed that mitigating global warming "would make it markedly easier to achieve many aspects of sustainable development, with greater potential to eradicate poverty and reduce inequalities." In a first-of-its-kind study that combines assessments of the risks of toxic emissions (e.g., fine particulate matter), ...
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Medicine 2021-07-21

Exoskeletons have a problem: They can strain the brain

COLUMBUS, Ohio - Exoskeletons - wearable devices used by workers on assembly lines or in warehouses to alleviate stress on their lower backs - may compete with valuable resources in the brain while people work, canceling out the physical benefits of wearing them, a new study suggests. The study, published recently in the journal Applied Ergonomics, found that when people wore exoskeletons while performing tasks that required them to think about their actions, their brains worked overtime and their bodies competed with the exoskeletons rather than working in harmony with them. The study indicates that exoskeletons may place enough burden on the brain that potential benefits to the body are negated. "It's almost like dancing with a really bad partner," said ...
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New approach eradicates breast cancer in mice
Medicine 2021-07-21

New approach eradicates breast cancer in mice

CHAMPAIGN, Ill. -- A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels. Led by scientists at the University of Illinois Urbana-Champaign, the research team reports the findings in the journal Science Translational Medicine. "Even when a few breast cancer cells do survive, enabling tumors to regrow over several months, the tumors that regrow remain completely ...
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Medicine 2021-07-21

Study finds calcium precisely directs blood flow in the brain

Unlike the rest of the body, there is not enough real estate in the brain for stored energy. Instead, the brain relies on the hundreds of miles of blood vessels within it to supply fresh energy via the blood. Yet, how the brain expresses a need for more energy during increased activity and then directs its blood supply to specific hot spots was, until now, poorly understood. Now, University of Maryland School of Medicine and University of Vermont researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions. In their new paper, published on July 21 in Science Advances, ...
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Science 2021-07-21

Powerline failures and wind speeds are strongest drivers of land area burned by Santa Ana wind fires

Every year, Santa Ana Winds drive some of the largest wildfires in Southern California during autumn and winter, and a new analysis of 71 years of data suggests that the total amount of land burned is determined more by wind speed and power line ignitions than by temperature and precipitation. The findings suggest that maintaining utility lines and carefully planning urban growth to reduce powerline ignitions may help to reduce future losses from Santa Ana-driven autumn and winter fires, which occur far less frequently than summer fires but account for the largest blazes annually. While California's summer fires are typically driven by an abundance of fuels such as dry twigs and logs, and are often ignited by lightning in remote areas, the state's autumn and winter fires are typically ...
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New algorithm flies drones faster than human racing pilots
Technology 2021-07-21

New algorithm flies drones faster than human racing pilots

To be useful, drones need to be quick. Because of their limited battery life they must complete whatever task they have - searching for survivors on a disaster site, inspecting a building, delivering cargo - in the shortest possible time. And they may have to do it by going through a series of waypoints like windows, rooms, or specific locations to inspect, adopting the best trajectory and the right acceleration or deceleration at each segment. Algorithm outperforms professional pilots The best human drone pilots are very good at doing this and have so far always outperformed autonomous systems in drone racing. Now, a research group at the University of Zurich (UZH) has created an algorithm that can find the quickest ...
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Science 2021-07-21

Study finds lifting advice doesn't stand up for everyone

Commonly accepted advice to keep a straight back and squat while lifting in order to avoid back pain has been challenged by new Curtin University research. The research examined people who had regularly performed manual lifting through their occupation for more than five years and found those who experienced low back pain as a result were more likely to use the recommended technique of squatting and keeping a straight back, while those without back pain tended not to adhere to the recommended lifting advice. Lead researcher PhD candidate Nic Saraceni from the Curtin School of Allied Health said the study required participants to each perform 100 lifts using two differently weighted boxes, with researchers ...
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Medicine 2021-07-21

Take two: Integrating neuronal perspectives for richer results

Every brain function, from standing up to deciding what to have for dinner, involves neurons interacting. Studies focused on neuronal interactions extend across domains in neuroscience, primarily using the approaches of spike count correlation or dimensionality reduction. Pioneering research from Carnegie Mellon University has identified a way to bridge these approaches, resulting in a richer understanding of neuronal activity. Neurons use electrical and chemical signals to relay information throughout the body, and we each have billions of them. Understanding how neurons interact with each other is important, ...
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Origami comes to life with new shape-changing materials
Engineering 2021-07-21

Origami comes to life with new shape-changing materials

Imagine opening up a book of nature photos only to see a kaleidoscope of graceful butterflies flutter out from the page. Such fanciful storybooks might soon be possible thanks to the work of a team of designers and engineers at CU Boulder's ATLAS Institute. The group is drawing from new advancements in the field of soft robotics to develop shape-changing objects that are paper-thin, fast-moving and almost completely silent. The researchers' early creations, which they've dubbed "Electriflow," include origami cranes that can bend their necks, flower petals ...
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Medicine 2021-07-21

Enamel defects as biomarkers for exposure to environmental stressors

Alexandria, Va., USA - IADR President Pamela Den Besten presented and chaired the IADR President's Symposium "Enamel Defects as Biomarkers for Exposure to Environmental Stressors" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021. Enamel pathologies may result from mutations of genes involved in amelogenesis, or from specific environmental ...
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Medicine 2021-07-21

Oral and general health associations using machine learning prediction algorithms

Alexandria, Va., USA - Muthuthanthrige Cooray, Tohoku University, Sendai, Japan, presented the oral session "Oral and General Health Associations Using Machine Learning Prediction Algorithms" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021. General health and oral health are conventionally treated as separate entities within the healthcare delivery, however most general health and oral health problems share common ...
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Environment 2021-07-21

The challenge of capturing carbon

In the race to combat climate change, capturing carbon dioxide (CO2) emissions has been touted as a simple road to reach net-zero emissions by 2050. While the science behind carbon capture is sound, current technologies are expensive and not optimized for all settings. A cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, highlights the current state of carbon capture and work being done to improve the process. Although efficiency improvements and renewable power sources can help, they are often expensive and will not be enough to counter the billions of tons of CO2 sent into the atmosphere each year, writes Associate ...
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Kids eat more fruit and vegetables with longer seated lunch time
Science 2021-07-21

Kids eat more fruit and vegetables with longer seated lunch time

URBANA, Ill. - When kids sit down to eat lunch at school, fruits and vegetables may not be their first choice. But with more time at the lunch table, they are more likely to pick up those healthy foods. If we want to improve children's nutrition and health, ensuring longer school lunch breaks can help achieve those goals, according to research from the University of Illinois. "Ten minutes of seated lunch time or less is quite common. Scheduled lunch time may be longer, but students have to wait in line to get their food. And sometimes lunch periods are shared with recess. This means the amount of time children actually have to eat their meals is much less than the scheduled time," says ...
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