A new study by investigators from Brigham and Women's Hospital examined the relationship between active lifestyles and the risk of obstructive sleep apnea (OSA). The study followed around 130,000 men and women in the United States over a follow-up period of 10-to-18 years and found that higher levels of physical activity and lower levels of sedentary behavior were associated with a lower risk of OSA. Their results are published in the European Respiratory Journal. "In our study, higher levels of physical activity and fewer hours of TV watching, and sitting either at work or away from home ...

Not enough progress has been made to address physical inactivity worldwide, with adolescents and people living with disabilities (PLWD) among the least likely populations to have the support needed to meet the World Health Organization (WHO)'s physical activity guidelines. Global efforts to improve physical activity have stalled, with overall deaths caused by physical activity remaining at more than 5 million people per year. [1] Physical inactivity is linked to an increased risk of non-communicable diseases (NCDs) such as heart disease, diabetes, and some cancers and costs at least $54 billion per year in direct health care costs of which $31 billion is paid by the public sector. The slow progress to improve physical activity worldwide ...

Alexandria, Va., USA - The International Association for Dental Research (IADR) announced David Williams, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK, as the 2021 recipient of the IADR Gold Medal Award. Williams was recognized during the Opening Ceremonies of the virtual 99th General Session & Exhibition of the IADR, held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021. Williams is a Professor of Global Oral Health at Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK. He is currently Co-Chair ...

Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published. Up to half of the 45 million people worldwide who are living with Alzheimer's disease will experience psychotic episodes, a figure that is even higher in some other forms of dementia. Psychosis is linked to a faster deterioration in dementia. Despite this, there is no approved safe and effective treatment for these particularly distressing symptoms. In people with dementia, widely-used antipsychotics lead to sedation, falls and increased risk of deaths. Pimavanserin works by blocking serotonin 5HT2A ...

EAST LANSING, Mich. - In the wild, inheriting advantageous physical traits may be the difference between a long life and a short one. But for the spotted hyena, another kind of inheritance, one that has nothing to do with genetics, turns out to be extremely important for health and longevity -- social networks inherited from their mothers. A new study, based on 27 years of observational data from Michigan State University Distinguished Professor Kay Holekamp, expands a previously established theoretical model of spotted hyena social networking to show how these networks emerge, how long they last and how they affect a hyena's life trajectory. The paper is featured as the front cover for the journal Science. "There ...

Two recently published studies available on the National Institutes of Health (NIH) website indicate Epstein-Barr virus (EBV) reactivation may play a role both in the development of long COVID symptoms, as well as severe COVID-19 cases. The first evidence linking EBV reactivation to long COVID symptoms was discovered by Gold et al. (2021) and published in Pathogens. This study can be viewed on the NIH website here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233978/ "We ran Epstein-Barr virus serological tests on COVID-19 patients at least 90 days after testing positive for SARS-CoV-2 infection, comparing EBV ...

Alexandria, Va., USA - Walter Siqueira, University of Saskatchewan, Saskatoon, Canada, presented the poster "Self-collected Saliva and Courier Service - A Feasible Diagnostic Strategy for COVID-19" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021. Saliva has been proposed as a convenient and cost-effective biofluid for diagnostic purposes and in vitro studies have shown that the addition of stabilizers to saliva preserves it for up to 7-10 days at room temperature, but its translational application ...

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so. "Your chances of dying increase by 5-fold when you get infected by E. faecalis that can make cytolysin compared to those that cannot," said Wilfred van der Donk (MMG), a professor of chemistry and investigator of the Howard Hughes Medical Institute. "Cytolysin is an important molecule and it has been known since the 1930s, our lab determined the ...

Researchers from the University of Southern California (USC) Department of Computer Science and NVIDIA have unveiled a new simulator for robotic cutting that can accurately reproduce the forces acting on a knife as it slices through common foodstuffs, such as fruit and vegetables. The system could also simulate cutting through human tissue, offering potential applications in surgical robotics. The paper was presented at the Robotics: Science and Systems (RSS) Conference 2021 on July 16, where it received the Best Student Paper Award. In the past, researchers have had trouble creating intelligent ...

Los Alamos, N.M., July 21, 2021--A team of scientists at Los Alamos National Laboratory propose that modulated quantum metasurfaces can control all properties of photonic qubits, a breakthrough that could impact the fields of quantum information, communications, sensing and imaging, as well as energy and momentum harvesting. The results of their study were released yesterday in the journal Physical Review Letters, published by the American Physical Society. "People have studied classical metasurfaces for a long time," says Diego Dalvit, who works in the Condensed Matter and Complex Systems group at the Laboratory's Theoretical Division. "But we came up with this new idea, which was to modulate in time and space the optical properties of ...

Northwestern University researchers have developed a new framework using machine learning that improves the accuracy of interatomic potentials -- the guiding rules describing how atoms interact -- in new materials design. The findings could lead to more accurate predictions of how new materials transfer heat, deform, and fail at the atomic scale. Designing new nanomaterials is an important aspect of developing next-generation devices used in electronics, sensors, energy harvesting and storage, optical detectors, and structural materials. To design these materials, researchers create interatomic potentials through atomistic modeling, a computational approach that predicts how these materials behave by accounting for their ...

In a recently published paper, a research team, led by University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science Professor Emeritus Joseph M. Prospero, chronicles the history of African dust transport, including three independent "first" discoveries of African dust in the Caribbean Basin in the 1950s and 1960s. Every year, mineral-rich dust from North Africa's Sahara Desert is lifted into the atmosphere by winds and carried on a 5,000-mile journey across the North Atlantic to the Americas. African dust contains iron, phosphorus and other important nutrients that are essential for life in marine and terrestrial ...

BROOKLYN, New York, Weekday, Month xx, 2021 - The remarkable structural properties of the Venus' flower basket sponge (E. aspergillum) might seem fathoms removed from human-engineered structures. However, insights into how the organism's latticework of holes and ridges influences the hydrodynamics of seawater in its vicinity could lead to advanced designs for buildings, bridges, marine vehicles and aircraft, and anything that must respond safely to forces imposed by the flow of air or water. While past research has investigated the structure of the sponge, there have been few studies of the hydrodynamic fields surrounding and penetrating the organism, and whether, besides improving its mechanical ...

BROOKLYN, New York, Wednesday, July 21, 2021 - This week, at the 38th International Conference on Machine Learning (ICML 21), researchers at the END ...

Efforts to understand cardiac disease progression and develop therapeutic tissues that can repair the human heart are just a few areas of focus for the Feinberg research group at Carnegie Mellon University. The group's latest dynamic model, created in partnership with collaborators in the Netherlands, mimics physiologic loads on engineering heart muscle tissues, yielding an unprecedented view of how genetics and mechanical forces contribute to heart muscle function. "Our lab has been working for a long time on engineering and building human heart muscle tissue, so we can better ...

UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C. The END ...

For more than 30 years, scientists on the U.N.'s Intergovernmental Panel on Climate Change have focused on human-induced climate change. Their fifth assessment report led to the Paris Agreement in 2015 and, shortly after, a special report on the danger of global warming exceeding 1.5 degrees Celsius above pre-industrial levels. The Nobel Prize-winning team stressed that mitigating global warming "would make it markedly easier to achieve many aspects of sustainable development, with greater potential to eradicate poverty and reduce inequalities." In a first-of-its-kind study that combines assessments of the risks of toxic emissions (e.g., fine particulate matter), ...

COLUMBUS, Ohio - Exoskeletons - wearable devices used by workers on assembly lines or in warehouses to alleviate stress on their lower backs - may compete with valuable resources in the brain while people work, canceling out the physical benefits of wearing them, a new study suggests. The study, published recently in the journal Applied Ergonomics, found that when people wore exoskeletons while performing tasks that required them to think about their actions, their brains worked overtime and their bodies competed with the exoskeletons rather than working in harmony with them. The study indicates that exoskeletons may place enough burden on the brain that potential benefits to the body are negated. "It's almost like dancing with a really bad partner," said ...

CHAMPAIGN, Ill. -- A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels. Led by scientists at the University of Illinois Urbana-Champaign, the research team reports the findings in the journal Science Translational Medicine. "Even when a few breast cancer cells do survive, enabling tumors to regrow over several months, the tumors that regrow remain completely ...

Unlike the rest of the body, there is not enough real estate in the brain for stored energy. Instead, the brain relies on the hundreds of miles of blood vessels within it to supply fresh energy via the blood. Yet, how the brain expresses a need for more energy during increased activity and then directs its blood supply to specific hot spots was, until now, poorly understood. Now, University of Maryland School of Medicine and University of Vermont researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions. In their new paper, published on July 21 in Science Advances, ...

Every year, Santa Ana Winds drive some of the largest wildfires in Southern California during autumn and winter, and a new analysis of 71 years of data suggests that the total amount of land burned is determined more by wind speed and power line ignitions than by temperature and precipitation. The findings suggest that maintaining utility lines and carefully planning urban growth to reduce powerline ignitions may help to reduce future losses from Santa Ana-driven autumn and winter fires, which occur far less frequently than summer fires but account for the largest blazes annually. While California's summer fires are typically driven by an abundance of fuels such as dry twigs and logs, and are often ignited by lightning in remote areas, the state's autumn and winter fires are typically ...

To be useful, drones need to be quick. Because of their limited battery life they must complete whatever task they have - searching for survivors on a disaster site, inspecting a building, delivering cargo - in the shortest possible time. And they may have to do it by going through a series of waypoints like windows, rooms, or specific locations to inspect, adopting the best trajectory and the right acceleration or deceleration at each segment. Algorithm outperforms professional pilots The best human drone pilots are very good at doing this and have so far always outperformed autonomous systems in drone racing. Now, a research group at the University of Zurich (UZH) has created an algorithm that can find the quickest ...

Commonly accepted advice to keep a straight back and squat while lifting in order to avoid back pain has been challenged by new Curtin University research. The research examined people who had regularly performed manual lifting through their occupation for more than five years and found those who experienced low back pain as a result were more likely to use the recommended technique of squatting and keeping a straight back, while those without back pain tended not to adhere to the recommended lifting advice. Lead researcher PhD candidate Nic Saraceni from the Curtin School of Allied Health said the study required participants to each perform 100 lifts using two differently weighted boxes, with researchers ...

Every brain function, from standing up to deciding what to have for dinner, involves neurons interacting. Studies focused on neuronal interactions extend across domains in neuroscience, primarily using the approaches of spike count correlation or dimensionality reduction. Pioneering research from Carnegie Mellon University has identified a way to bridge these approaches, resulting in a richer understanding of neuronal activity. Neurons use electrical and chemical signals to relay information throughout the body, and we each have billions of them. Understanding how neurons interact with each other is important, ...

Imagine opening up a book of nature photos only to see a kaleidoscope of graceful butterflies flutter out from the page. Such fanciful storybooks might soon be possible thanks to the work of a team of designers and engineers at CU Boulder's ATLAS Institute. The group is drawing from new advancements in the field of soft robotics to develop shape-changing objects that are paper-thin, fast-moving and almost completely silent. The researchers' early creations, which they've dubbed "Electriflow," include origami cranes that can bend their necks, flower petals ...