University of Utah paleontologists David Peterman and Kathleen Ritterbush know that it's one thing to use math and physics to understand how ancient marine creatures moved through the water. It's another thing to actually put replicas of those creatures into the water and see for themselves. They're among the scientists who are, through a range of methods including digital models and 3-D printed replicas, "de-fossilizing" animals of the past to learn how they lived. Peterman, Ritterbush and their colleagues took 3-D printed reconstructions of fossil cephalopods to actual water tanks (including a University of Utah swimming pool) to see how their shell structure may have been tied to their movement and lifestyle. Their research is published in PeerJ ...

Bottom Line: The investigational therapeutic ficlatuzumab in combination with chemotherapy showed signs of clinical efficacy in patients with relapsed/refractory acute myeloid leukemia. Journal in Which the Study was Published: Blood Cancer Discovery, a journal of the American Association for Cancer Research Author: Senior author Charalambos Andreadis, MD, professor of clinical medicine at the University of California, San Francisco (UCSF), and first author Victoria Wang, MD, PhD, an assistant professor of hematology and oncology at UCSF Background: "Only about half of patients with acute myeloid leukemia (AML) will achieve long-term disease control," said ...

Byron Bay (16/7/2021) - A new study from WCS and WWF reveals that nearly 20 percent of tropical Intact Forest Landscapes (IFLs) overlap with concessions for extractive industries such as mining, oil and gas. The total area of overlap is 376,449 square miles (975,000 square kilometers), about the size of Egypt. Mining concessions overlap most with tropical IFLs, at 11.33 percent of the total area, while oil and gas concessions overlap with 7.85 percent of the total area. IFLs are globally important for conserving biodiversity and fighting climate change. ...

Oncotarget published "Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab" which reported that a disappearance of RAS mutations in the plasma of about 50% of mCRCs treated with bevacizumab-based chemotherapy has been reported. Using next-generation sequencing and real-time PCR approaches, these authors characterized the primary tumor and paired liver metastases in 28 RAS mutant mCRCs. RAS mutant alleles are at the same percentage in PT and liver metastases in the control group, while a significant reduction of the level ...

Hiroshi Tanimoto, Director of the Earth System Division at the National Institute for Environmental Studies (NIES), Japan, and Astrid Müller together with their international research team, have developed a new method to evaluate satellite observations of XCO2 over open ocean areas, which are currently inaccessible through established validation network sites. In the new approach, a reference CO2 dataset is formulated by combining cargo ship and passenger aircraft observations which were conducted in cooperation with operators of the private sector. (Background) After the Paris Agreement entered into force, commitment to reduce greenhouse gas emissions are being expedited. CO2 is the most important anthropogenically produced greenhouse ...

Researchers from National University of Singapore and Stanford University published a new paper in the Journal of Marketing that investigates how rural consumers in India shift their expenditures towards branded consumption when they migrate to urban areas. The study, forthcoming in the Journal of Marketing, is titled "The Economic and Social Impacts of Migration on Brand Expenditure: Evidence from Rural India" and is authored by Vishal Narayan and Shreya Kankanhalli. With Covid-19 disrupting work patterns and increased investment in rural employment, many of India's 450 million internal migrants are returning to their villages. Consumer goods companies view this as an opportunity to grow their presence in rural markets, with migrants serving as unofficial brand ambassadors ...

A team of researchers from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the University of Liège and the Helmholtz Institute Erlangen-Nürnberg for Renewable Energy have developed a microswimmer that appears to defy the laws of fluid dynamics: their model, consisting of two beads that are connected by a linear spring, is propelled by completely symmetrical oscillations. The Scallop theorem states that this cannot be achieved in fluid microsystems. The findings have now been published in the academic journal Physical Review Letters. Scallops can swim in water by quickly clapping their shells together. They are large enough to still be able to move forwards through the moment of inertia while the scallop ...

The UK government's latest pandemic plan involves recklessly exposing millions of people to the acute and long-term effects of mass infection, warn experts in The BMJ today. A strategy that chooses mass infection in the young now over vaccination in order to achieve greater population immunity to protect the vulnerable in winter, is "unethical and unscientific" say Dr Deepti Gurdasani and colleagues. Instead of allowing infections to rise, they urge the government to take urgent actions to inform and protect the public and prepare for autumn. These include outlining a long-term strategy for pandemic control, keeping basic measures ...

A team of researchers from Stanford University and the University of Leuven in Belgium has further elucidated an intriguing process that could be an important step toward a methanol fuel economy with abundant methane as the feedstock, an advance that could fundamentally change how the world uses natural gas. Methanol - the simplest alcohol - is used to make various products, like paints and plastics, and as an additive to gasoline. Rich in hydrogen, methanol can drive new-age fuel cells that could yield significant environmental benefits. If natural gas, of which methane ...

In a new study from University of California San Diego School of Medicine, researchers have confirmed that patients taking statin medications had a 41 percent lower risk of in-hospital death from COVID-19. The findings were published July 15, 2021 in PLOS ONE and expand upon prior research conducted at UC San Diego Health in 2020. Statins are commonly used to reduce blood cholesterol levels by blocking liver enzymes responsible for making cholesterol. They are widely prescribed: The Centers for Disease Control estimates that 93 percent of patients who use a cholesterol-lowering drug use a statin. "When faced with this virus at the beginning of the pandemic, there was a lot of speculation ...

Undeniably the shark movie to end all shark movies, the 1975 blockbuster, Jaws, not only smashed box office expectations, but forever changed the way we felt about going into the water - and how we think about sharks. Now, more than 40 years (and 100+ shark movies) on, people's fear of sharks persists, with researchers at the University of South Australia concerned about the negative impact that shark movies are having on conservation efforts of this often-endangered animal. In a world-first study, conservation psychology researchers, UniSA's Dr Briana Le Busque and Associate Professor Carla Litchfield have evaluated how sharks are portrayed in movies, finding that ...

CHAMPAIGN, Ill. -- A new study shows that it is possible to use mechanical force to deliberately alter chemical reactions and increase chemical selectivity - a grand challenge of the field. The study led by University of Illinois Urbana-Champaign researcher Jeffrey Moore and Stanford University chemist Todd Martinezz demonstrates how external mechanical forces alter atomic motions to manipulate reaction outcomes. The study findings are published in the journal Science. "We think of chemical reactions as molecules moving on a surface of potential energy in the way hikers follow the contour map of mountains and valleys along a trail," said lead author Yun ...

Scientists on the hunt for an unconventional kind of superconductor have produced the most compelling evidence to date that they've found one. In a pair of papers, researchers at the University of Maryland's (UMD) Quantum Materials Center (QMC) and colleagues have shown that uranium ditelluride (or UTe2 for short) displays many of the hallmarks of a topological superconductor--a material that may unlock new ways to build quantum computers and other futuristic devices. "Nature can be wicked," says Johnpierre Paglione, a professor of physics at UMD, the director of QMC and senior author on one of the papers. "There could be other reasons we're seeing all this wacky stuff, but ...

A new national study published in Public Health Nutrition on July 15 found that Americans experiencing food insufficiency were three times as likely to lack mental health support during the COVID-19 pandemic than those not experiencing food insufficiency. The most extreme form of food insecurity, food insufficiency occurs when families do not have enough eat. Among a nationally representative sample of 68,611 adults who participated in the US Census Household Pulse Survey in October 2020, 11% reported food insufficiency. Of those, 24% also reported an unmet mental health need compared to 9% of food-sufficient adults. "Hunger, exhaustion, and stress related to not getting enough food to eat may lead ...

A national study published in the Journal of Pediatrics found that Emergency Department (ED) visits by youth for self-harm were nearly 40 percent higher in rural areas compared to urban settings. Strikingly, ED visits by youth for self-inflicted firearm injuries were three times more common in rural areas. Youth from rural areas presenting to the ED for suicidal ideation or self-harm also were more likely to need to be transferred to another hospital for care, which underscores the insufficient mental health resources in rural hospitals. "Our study used pre-pandemic data, and we know that increased attention to youth mental health is even more pressing now everywhere, ...

WINSTON-SALEM, NC, July 15, 2021 - Answering a charge from the National Science Board, the RegenMed Development Organization (ReMDO), through its RegeneratOR Workforce Development Initiative, has released the results of a national survey of regenerative medicine biomanufacturing knowledge, skills, and abilities needed for successful employment in the regenerative medicine field. The National Science Board called for the creation of a skilled technical workforce driven by science and engineering in its 2019 report, "The Skilled Technical Workforce: Crafting America's Science and Engineering Enterprise." "The RegeneratOR initiative ...

A screening tool used to evaluate the need for endometrial cancer biopsies in women frequently misses the signs of this cancer in Black women, according to a new study released today in JAMA Oncology. Dr. Kemi Doll, the lead researcher, and a gynecologic oncologist with the University of Washington School of Medicine, says that the results of the study suggest that the current non-invasive option of transvaginal ultrasound, or TVUS, to determine the appropriateness of a biopsy is not sufficiently accurate or racially equitable with regards to Black women. "Black women have an over 90% higher mortality rate after diagnosis of endometrial cancer when compared with White women in the U.S.," Doll said. "This is a long-standing disparity ...

The arrival of plants on land about 400 million years ago may have changed the way the Earth naturally regulates its own climate, according to a new study led by researchers at UCL and Yale. The carbon cycle, the process through which carbon moves between rocks, oceans, living organisms and the atmosphere, acts as Earth's natural thermostat, regulating its temperature over long time periods. In a new study, published in the journal Nature, researchers looked at samples from rocks spanning the last three billion years and found evidence of a dramatic change in how this cycle functioned about 400 million years ago, when plants started to colonise land. Specifically, the researchers noted a ...

Add this to the list of real-life spidey senses: Harvard researchers have shown that jumping spiders are able to tell the difference between animate objects and inanimate objects -- an ability previously known only in vertebrates, including humans. Using a specialized treadmill system and a point-light display animation, the team of scientists found that these spiders are able to recognize biological motion. This type of motion refers to the visual movements that come from living organisms when they are moving. The visual cue is how people, even babies, can tell someone is another person just by the way their bodies move. Many animals can do this, too. The ability, which is critical for survival, is evolutionarily ancient since it is so widespread ...

Reducing greenhouse gas emissions (GHGs) and nitrogen water pollution from agriculture are top environmental priorities in the United States. Key to achieving climate goals is helping producers navigate carbon markets, while also helping the environment and improving farm income. A new tool developed by a University of Minnesota research team allows farmers to create a budget balance sheet of any nitrogen reduction plans and see the economic and environmental cost, return and margins, all customized to fields under their management. "With these numbers in mind, farmers can make more informed decisions on ...

(LOS ANGELES) - Many bodily functions in humans are manifested by mechanical deformations to the skin - from the stretching, bending and movement of muscles and joints to the flutter of a pulse at the wrist. These mechanical changes can be detected and monitored by measuring different levels of strain at various points throughout the body. In recent years, much attention has been focused on wearable sensors to measure these strains for use in personal health monitoring. Some of these sensors can detect high-level (40-100%) strains, such as those associated with the movements of fingers ...

A new protein-based vaccine candidate combined with a potent adjuvant provided effective protection against SARS-CoV-2 when tested in animals, suggesting that the combination could add one more promising COVID-19 vaccine to the list of candidates for human use. The protein antigen, based on the receptor binding domain (RBD) of SARS-CoV-2, was expressed in yeast instead of mammalian cells - which the authors say could enable a scalable, temperature-stable, low-cost production process well suited for deployment in the developing world. In a study by Maria Pino and colleagues, the adjuvant ...

Concern has grown about prison systems' use of extended solitary confinement as a way to manage violent and disruptive incarcerated people. A new study identified groups that are more likely to be placed in extended solitary management (ESM). The study found that individuals sent to ESM differed considerably from the rest of the prison population in terms of mental health, education, language, race/ethnicity, and age. The study, by researchers at Florida State University and the University of Cincinnati, appears in Justice Quarterly, a publication of the Academy of Criminal Justice Sciences. "Many ...

URBANA, Ill. - Corn growers can choose from a wide array of products to make the most of their crop, but the latest could bring seaweed extract to a field near you. The marine product is just one class in a growing market of crop biostimulants marketed for corn. Biostimulants benefit crops and soil, but the dizzying array of products has farmers confused, according to Fred Below, corn and soybean researcher at the University of Illinois. "Farmers hear the term 'plant biostimulant' and think they all do the same thing, and can be used in the same way at the same time. But that's not the case. There's huge confusion ...

Earth's climate was relatively stable for a long period of time. For three billion years, temperatures were mostly warm and carbon dioxide levels high - until a shift occurred about 400 million years ago. A new study suggests that the change at this time was accompanied by a fundamental alteration to the carbon-silicon cycle. "This transformation of what was a consistent status quo in the Precambrian era into the more unstable climate we see today was likely due to the emergence and spread of new life forms," said Professor Philip Pogge von Strandmann, a geoscientist at Johannes ...