Measuring hemoglobin levels with AI microscope, microfluidic chips
2021-02-23
WASHINGTON, February 23, 2021 -- One of the most performed medical diagnostic tests to ascertain the health of patients is a complete blood count, which typically includes an estimate of the hemoglobin concentration. The hemoglobin level in the blood is an important biochemical parameter that can indicate a host of medical conditions including anemia, polycythemia, and pulmonary fibrosis.
In AIP Advances, by AIP Publishing, researchers from SigTuple Technologies and the Indian Institute of Science describe a new AI-powered imaging-based tool to estimate hemoglobin levels. The setup was developed in conjunction with a microfluidic chip and ...
Effect of layperson-delivered, empathy-focused program of telephone calls on loneliness, depression, anxiety during COVID-19 pandemic
2021-02-23
What The Study Did: A randomized clinical trial, this study reports that a layperson-delivered, empathy-oriented telephone call program reduced loneliness, depression and anxiety compared with the control group and improved the general mental health of participants within four weeks.
Authors: Maninder K. Kahlon, Ph.D., of the University of Texas at Austin, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(10.1001/jamapsychiatry.2021.0113)
Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and ...
COVID-19 communication
2021-02-23
What The Article Says: In this narrative medicine essay, a medical school professor expresses gratitude for the caring and empathy expressed by the team caring for her mother hospitalized with COVID-19 and emphasizes the importance of humanity and compassion over facts and statistics for families physically separated from their critically ill loved ones.
Authors: Lisa M. Meeks, Ph.D., of the University of Michigan Medical School in Ann Arbor, is the author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2021.0119)
Editor's ...
Tobacco exposure in kids, risk of increased blood pressure
2021-02-23
What The Study Did: Researchers investigated whether children and adolescents who smoked or lived with a smoker had an increased risk of elevated blood pressure.
Authors: Rebecca V. Levy, B.M., B.Ch., M.Sc., of the Montefiore Medical Center in Bronx, New York is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2020.37936)
Editor's Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and ...
Simply speaking while infected can potentially spread COVID-19
2021-02-23
WASHINGTON, February 23, 2021 -- COVID-19 can spread from asymptomatic but infected people through small aerosol droplets in their exhaled breath. Most studies of the flow of exhaled air have focused on coughing or sneezing, which can send aerosols flying long distances.
However, speaking while near one another is also risky since the virus can be ejected by merely talking.
In Physics of Fluids, by AIP Publishing, scientists in Japan use smoke and laser light to study the flow of expelled breath near and around two people conversing in various relative postures commonly found in the service industry, such as in hair salons, medical exam rooms, or long-term care facilities. ...
Low-level jets create winds of change for turbines
2021-02-23
WASHINGTON, February 23, 2021 -- As one of the leading sources of clean and renewable energy, global wind power capacity has increased more than fivefold over the past decade, leading to larger turbines and pushing wind technology to its limits.
"These much larger turbines are operating in very different atmospheric layers than smaller turbines used 5-10 years ago," said Srinidhi Gadde, one of the authors of a paper in the Journal of Renewable and Sustainable Energy, from AIP Publishing, that examines the impacts of turbine height. "At these scales, local meteorology and extreme shear events, which frequently occur, can impact ...
Parasitic plants conspire to keep hosts alive
2021-02-23
The plant that encourages kissing at Christmas is in fact a parasite, and new research reveals mistletoe has an unusual feeding strategy.
Like other plants, mistletoe is capable of using sunlight to create its own food, a process called photosynthesis. However, it prefers to siphon water and nutrients from other trees and shrubs, using "false roots" to invade its hosts.
"Plants are autotrophic, they make their own food. Humans are heterotrophic, we eat it," explained UC Riverside plant-insect ecologist Paul Nabity. "Mistletoe are mostly heterotrophic, but they can switch if they want to."
Nabity's team found when two mistletoes invade the same tree, they increase photosynthesis to get the nutrients they need, essentially sharing the ...
Kittens could hold key to understanding deadly diarrheal disease in children
2021-02-23
Kittens could be the model for understanding infectious, sometimes deadly, diarrheal disease in both animals and children, according to new research from North Carolina State University.
Diarrheagenic Escherichia coli (DEC) bacteria cause lethal diarrheal disease in children worldwide, killing up to 120,000 children under the age of five annually. Atypical enteropathic Escherichia coli (aEPEC) are a form of DEC increasingly associated with diarrheal disease in humans and in kittens.
"We were looking for causes of infectious diarrhea in kittens, which has a high mortality rate, and came across this pathogen," says Jody Gookin, FluoroScience Distinguished Professor in Veterinary Scholars Research Education at NC State and corresponding ...
Genetic tool improves estimation of prostate cancer risk in diverse ethnic/racial groups
2021-02-23
Building upon previous research, an international team led by scientists at University of California San Diego School of Medicine, has validated a more inclusive and comprehensive genetic tool for predicting age of onset of aggressive prostate cancer, a disease that killed more than 33,000 American men in 2020.
Reporting in the February 23, 2021 online edition of Nature Communications, the researchers describe the performance of a polygenic hazard score (PHS) -- a mathematical estimate of an individuals' age-specific genetic risk for developing a disease -- in a multi-ethnic patient population.
"Genetic tools to predict a man's lifetime risk of prostate cancer might allow us to target cancer screening efforts to the men who are most likely to need it. We are ...
University of Minnesota researchers develop two new rapid COVID-19 diagnostic tests
2021-02-23
MINNEAPOLIS/ST.PAUL (02/23/2021) -- University of Minnesota Medical School researchers have developed two new rapid diagnostic tests for COVID-19 - one to detect COVID-19 variants and one to help differentiate with other illnesses that have COVID-19-like symptoms. The findings were recently published in the journal Bioengineering.
Although many people are hopeful about COVID-19 vaccines, widespread vaccine distribution isn't predicted to be available until several months from now. Until that happens, the ability to diagnose COVID-19 quickly and accurately is crucial to help minimize loss of life and ...
Protective ship coatings as an underestimated source of microplastic pollution
2021-02-23
Shipping traffic can be a major source of tiny plastic particles floating in the sea, especially out in the open ocean. In a paper published in the scientific journal Environmental Science & Technology, a team of German environmental geochemists based at the University of Oldenburg's Institute of Chemistry and Biology of the Marine Environment and led by Dr Barbara Scholz-Boettcher for the first time provides an overview of microplastics mass distribution in the North Sea.
The scientists found that most of the plastic particles in water samples taken from the German Bight, an area in the south-eastern corner of the North Sea which encompasses some of the world's busiest shipping lanes, originate from binders used in marine paints. "Our hypothesis is that ships leave ...
New blood pressure-lowering guidelines could benefit 25 million americans with chronic kidney disease
2021-02-23
A recommendation for more intensive blood pressure management from an influential global nonprofit that publishes clinical practice guidelines in kidney disease could, if followed, benefit nearly 25 million Americans, according to an analysis led by researchers at the Johns Hopkins Bloomberg School of Public Health.
The new recommendation from Kidney Disease: Improving Global Outcomes, a global nonprofit that develops evidence-based clinical practice guidelines in kidney disease, is aimed at doctors to help them to reduce blood pressure for chronic kidney disease patients whose systolic blood pressure levels are over 120 mmHg. Blood pressure can be reduced using antihypertensive medications and lifestyle modifications. ...
Multi-ethnic neighborhoods in England retain diversity unlike in the U.S.
2021-02-23
Multi-ethnic neighborhoods in England retain their diversity and are much more stable than such neighborhoods in the U.S., according to geographers from the U.S. and U.K. The team examined how neighborhood diversity has changed on a national scale from 1991 to 2011 using U.K. Census data.
Past studies of this kind have often focused on neighborhoods in which the presence of two or three different ethnic groups constituted a diverse neighborhood but this study applied a more rigorous standard. A multi-ethnic neighborhood had to have at least five or more ethnic groups represented and no group could represent more ...
'Good bacteria' in breast milk changes over time
2021-02-23
The cocktail of beneficial bacteria passed from mother to infant through breast milk changes significantly over time and could act like a daily booster shot for infant immunity and metabolism. The research, conducted by scientists from Montreal and Guatemala and published in Frontiers in Microbiology, has important implications for infant development and health.
Researchers discovered a range of microbiome species never before identified in human milk. Until now, relatively little was known about the role microbiome bacteria play in breast milk. These bacteria are thought to protect the infant gastrointestinal tract and improve aspects of long-term health, such as allergy ...
Toxins from one bacterial species contribute to genetic diversity of others
2021-02-23
A toxin produced by bacteria as a defence mechanism causes mutations in target bacteria that could help them survive, according to a study published today in eLife.
The finding suggests that competitive encounters between bacterial cells could have profound consequences on the evolution of bacterial populations.
When bacterial cells come into contact, they often produce toxins as a defence mechanism. Although it is known that the bacteria producing these toxins have a competitive advantage, exactly how the toxins affect the recipient cells is less clear.
"Undergoing intoxication is not always detrimental for cells - there are scenarios in which encountering a toxin could provide a benefit, such as generating antibiotic ...
Biopolymer-coated nanocatalyst can help realize a hydrogen fuel-driven future
2021-02-23
To combat climate change, shifting from fossil fuels to clean and sustainable energy sources is imperative. A popular candidate in this regard is hydrogen, an eco-friendly fuel that produces only water when used. However, the efficient methods of hydrogen production are usually not eco-friendly. The eco-friendly alternative of splitting water with sunlight to produce hydrogen is inefficient and suffers from low stability of the photocatalyst (material that facilitates chemical reactions by absorbing light). How does one address the issue of developing a stable and efficient photocatalyst?
In a study recently published in Applied Catalysis B: Environmental, ...
A memory without a brain
2021-02-23
Having a memory of past events enables us to take smarter decisions about the future. Researchers at the Max-Planck Institute for Dynamics and Self-Organization (MPI-DS) and the Technical University of Munich (TUM) have now identified how the slime mold Physarum polycephalum saves memories - although it has no nervous system.
The ability to store and recover information gives an organism a clear advantage when searching for food or avoiding harmful environments. Traditionally it has been attributed to organisms that have a nervous system.
A new study authored by Mirna Kramar (MPI-DS) and Prof. Karen Alim (TUM and MPI-DS) challenges this view by uncovering the surprising abilities of a highly dynamic, single-celled organism to store and ...
'Problem of missing ice' finally solved by movement of the earth's crust
2021-02-23
During ice ages, the global mean sea level falls because large amounts sea water are stored in the form of huge continental glaciers. Until now, mathematical models of the last ice age could not reconcile the height of the sea level and the thickness of the glacier masses: the so-called Missing Ice Problem. With new calculations that take into account crustal, gravitational and rotational perturbation of the solid Earth, an international team of climate researchers has succeeded in resolving the discrepancy, among them Dr. Paolo Stocchi from the Royal Netherlands Institute for Sea Research (NIOZ). The study, now published in the ...
Actively preparing or watching others prepare food can lead to eating more
2021-02-23
During this unique study, a team of researchers led by Professor Jane Ogden from the University of Surrey investigated the impact of actively preparing or watching others prepare food (e.g., on a cooking show) versus distraction away from this focus. Researchers sought to understand how this may affect the amount of food consumed and influence the desire to continue eating.
To investigate this further, eighty female participants were recruited and assigned to one of four groups: active food preparation (preparing a cheese wrap within 10 minutes), video food preparation (watching a video of a researcher preparing a cheese wrap), distraction ...
Fat cells may influence how the body reacts to heart failure, study shows
2021-02-23
University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients.
In a recent study published in the American Journal of Physiology, Jason Dyck, professor of pediatrics in the Faculty of Medicine & Dentistry and director of the U of A's Cardiovascular Research Centre, found that mice with heart failure that were treated with a drug blocking the release of fat into the bloodstream from fat cells saw less inflammation in the heart and throughout the body, and had better outcomes than a control group.
"Many people believe that, by definition, heart failure is only ...
LSU Health New Orleans study finds disadvantaged census tracts linked to COVID incidence
2021-02-23
New Orleans, LA - An LSU Health New Orleans School of Public Health study reports a positive association between social vulnerability and COVID-19 incidence at the census tract level and recommends that more resources be allocated to socially vulnerable populations to reduce the incidence of COVID-19. The findings are published in Frontiers in Public Health, available END ...
Gay men who 'sound gay' encounter more stigma and discrimination from heterosexual peers
2021-02-23
Gay men are more likely than lesbian women to face stigma and avoidant prejudice from their heterosexual peers due to the sound of their voice, a new study in the British Journal of Social Psychology reports. Researchers also found that gay men who believe they sound gay anticipate stigma and are more vigilant regarding the reactions of others.
During this unique study researchers from the University of Surrey investigated the role of essentialist beliefs -- the view that every person has a set of attributes that provide an insight into their identity -- of heterosexual, lesbian ...
First DNA extracted from modern, ancient and fossil tropical shells
2021-02-23
In Wonderland, Alice drank a potion to shrink herself. In nature, some animal species shrink to escape the attention of human hunters, a process that takes from decades to millennia. To begin to understand the genetics of shrinking, scientists working at the Smithsonian Tropical Research Institute (STRI) in Panama successfully extracted DNA from marine shells. Their new technique will not only shed light on how animals from lizards to lemurs shrink, it will reveal many other stories hidden in shells.
"Humans are unique as predators," said Alexis Sullivan, doctoral student at Penn ...
Machine learning method identifies precancerous colon polyps
2021-02-23
OAK BROOK, Ill. - A machine learning algorithm helps accurately differentiate benign and premalignant colorectal polyps on CT colonography scans, according to a study published in the journal Radiology.
Colorectal cancer is among the three most common causes of cancer-related death among men and women in industrialized countries. Most types of colorectal cancer originate from adenomatous polyps--gland-like growths on the mucous membrane lining the large intestine--that develop over several years. Early detection and removal of these precancerous polyps can reduce the incidence and mortality of colorectal cancer.
During the last two decades, CT colonography emerged as a noninvasive ...
Innate immune system worsens the situation in severe COVID-19
2021-02-23
Peer review/observational study/people
In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients. This is shown in an Uppsala University study published in the journal Frontiers in Immunology.
Blood contains numerous proteins that constitute the body's primary barrier, by both recognising and destroying microorganisms, including SARS-CoV-2 (the virus that causes COVID-19). These proteins are part of the intravascular innate immune system (IIIS), which consists of certain white blood cells, platelets and what are known as the cascade systems of the blood.
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