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Genetic variations associated with traits underlying type 2 diabetes in Mexican-Americans

2014-12-17
WINSTON-SALEM, N.C. - Dec. 17, 2014 - While people of Mexican ancestry are nearly twice as likely to develop Type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin. In an effort to understand why Mexicans are disproportionately affected by the disease, researchers at Wake Forest Baptist Medical Center led the largest study to date to examine the underlying causes. The study is published in the Dec. 17 issue of Diabetes. "Type 2 diabetes is really about how you dispose of your glucose - how long it ...

Even in restored forests, extreme weather strongly influences wildfire's impacts

2014-12-17
DAVIS, Calif. -- The 2013 Rim Fire, the largest wildland fire ever recorded in the Sierra Nevada region, is still fresh in the minds of Californians, as is the urgent need to bring forests back to a more resilient condition. Land managers are using fire as a tool to mimic past fire conditions, restore fire-dependent forests, and reduce fuels in an effort to lessen the potential for large, high-intensity fires, like the Rim Fire. A study led by the U.S. Forest Service's Pacific Southwest Research Station (PSW) and recently published in the journal Forest Ecology and Management ...

Heat boosts phthalate emissions from vinyl crib mattress covers

2014-12-17
The U.S. continues to look at the use and regulation of phthalates, which have been associated with health problems. Of particular concern is the safety of these plastic additives to children. A new study aims to improve our understanding of one possible exposure route for babies: vinyl crib mattress covers. Scientists report in ACS' Environmental Science & Technology that as these covers warm up, they emit more phthalates into the air. Ying Xu and Yirui Liang note that previous studies have linked phthalates, which soften plastics, to potential health effects, including ...

New Notre Dame paper offers novel insights into pathogen behavior

2014-12-17
A new study by a team of researchers that includes University of Notre Dame scientists Joshua Shrout and Mark Alber provides new insights into the behavior of an important bacterial pathogen. Alber, Vincent J. Duncan Family Professor of Applied Mathematics, and Schrout, an associate professor of civil and environmental engineering and earth sciences, studied Pseudomonas aeruginosa, an opportunistic pathogen responsible for both acute and persistent infections. "While this ubiquitous environmental bacterium rarely infects healthy people, it is a common pathogen among ...

Stroke patients experience superior outcomes with intra-arterial treatment vs. tPA

Stroke patients experience superior outcomes with intra-arterial treatment vs. tPA
2014-12-17
ALAMEDA, Calif. - December 17, 2014 - Penumbra, Inc., the market leader in intra-arterial stroke treatment, announced that an independent study published online today in the New England Journal of Medicine found that intra-arterial stroke treatment, including the company's clot extraction technology, was shown to be significantly more effective than medical management with tissue plasminogen activator (tPA), which is the current standard of care. The findings of this randomized, controlled comparative effectiveness trial of stroke treatment have the potential to change ...

New class of synthetic molecules mimics antibodies

New class of synthetic molecules mimics antibodies
2014-12-17
New Haven, Conn. - A Yale University lab has crafted the first synthetic molecules that have both the targeting and response functions of antibodies. The new molecules -- synthetic antibody mimics (SyAMs) -- attach themselves simultaneously to disease cells and disease-fighting cells. The result is a highly targeted immune response, similar to the action of natural human antibodies. "Unlike antibodies, however, our molecules are synthetic organic compounds that are approximately one-twentieth the size of antibodies," said David A. Spiegel, a professor of chemistry at ...

A new strategy for developing drugs to fight cancer and other diseases

2014-12-17
Promising treatments known as biologics are on the market and under development for many serious illnesses such as cancer, but some of them come with high risks, even lethal ones. Now scientists have produced a novel class of molecules that could be as effective but without the dangerous side effects. They report their work on these compounds, which they tested on prostate cancer cells, in ACS' Journal of the American Chemical Society. David A. Spiegel and colleagues explain that biologics are protein-based therapies that have revolutionized cancer treatment over the ...

Guelph researchers recipe: Cook farm waste into energy

2014-12-17
It takes some cooking, but turning farm waste into biofuels is now possible and makes economic sense, according to preliminary research from the University of Guelph. Guelph researchers are studying how to make biofuels from farm waste, especially "wet" waste that is typically difficult to use. They have developed a fairly simple procedure to transport waste and produce energy from it. Scientists have struggled to find uses for wet and green waste, including corn husks, tomato vines and manure. Dry farm waste, such as wood chips or sawdust, is easier to use for generating ...

Is the label 'hypoallergenic' helpful or just marketing hype?

2014-12-17
Many consumers seek out shampoos, soaps and cosmetics that are labeled "hypoallergenic" or "dermatologist tested," words that imply the products are safe to use. But recent research gives shoppers reason to question what those labels really mean. Now some scientists and consumer advocates are calling for change, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society. Britt E. Erickson, a senior editor at C&EN, notes that the definitions of the terms "hypoallergenic" and "dermatologist tested/recommended" ...

Study finds that employees who are open about religion are happier

2014-12-17
MANHATTAN, KANSAS -- It may be beneficial for employers to not only encourage office Christmas parties but also celebrate holidays and festivals from a variety of religions, according to a Kansas State University researcher. Sooyeol Kim, doctoral student in psychological sciences, was involved in a collaborative study that found that employees who openly discuss their religious beliefs at work are often happier and have higher job satisfaction than those employees who do not. "For many people, religion is the core of their lives," Kim said. "Being able to express important ...

Study hints that ancient Earth made its own water -- geologically

2014-12-17
SAN FRANCISCO--A new study is helping to answer a longstanding question that has recently moved to the forefront of earth science: Did our planet make its own water through geologic processes, or did water come to us via icy comets from the far reaches of the solar system? The answer is likely "both," according to researchers at The Ohio State University-- and the same amount of water that currently fills the Pacific Ocean could be buried deep inside the planet right now. At the American Geophysical Union (AGU) meeting on Wednesday, Dec. 17, they report the discovery ...

Top weather conditions that amplify Lake Erie algal blooms revealed

2014-12-17
SAN FRANCISCO--Of the many weather-related factors that contribute to harmful algal blooms (HABs) in Lake Erie, a new study has identified one as most important: the wind. Over a 10-year period in Lake Erie, wind speed contributed more consistently to HABs than sunshine or even precipitation, researchers at The Ohio State University and their colleagues found. The ongoing study is unusual, in that researchers are building the first detailed analyses of how the various environmental factors influence each other--in the context of satellite studies of Lake Erie. They ...

Anti-diabetic drug springs new hope for tuberculosis patients

2014-12-17
Singapore, Date - A more effective treatment for tuberculosis (TB) could soon be available as scientists have discovered that Metformin (MET), a drug for treating diabetes, can also be used to boost the efficacy of TB medication without inducing drug resistance. This discovery was made by a team of international scientists led by the Singapore Immunology Network (SIgN), a research institute under the Agency for Science, Technology and Research (A*STAR), Singapore. TB is an air-borne infectious disease caused by a bacterium called Mycobacterium tuberculosis (Mtb), which ...

Asteroid that wiped out dinosaurs may have nearly knocked off mammals, too

Asteroid that wiped out dinosaurs may have nearly knocked off mammals, too
2014-12-17
The extinction of the dinosaurs 66 million years ago is thought to have paved the way for mammals to dominate, but a new study shows that many mammals died off alongside the dinosaurs. Metatherian mammals--the extinct relatives of living marsupials ("mammals with pouches", such as opossums) thrived in the shadow of the dinosaurs during the Cretaceous period. The new study, by an international team of experts on mammal evolution and mass extinctions, shows that these once-abundant mammals nearly followed the dinosaurs into oblivion. When a 10-km-wide asteroid struck ...

Regulation of maternal miRNAs in early embryos revealed

2014-12-17
The Center for RNA Research at the Institute for Basic Science (IBS) has succeeded in revealing, for the first time, the mechanism of how miRNAs, which control gene expression, are regulated in the early embryonic stage. The IBS researchers have verified that maternally inherited miRNAs are highly adenylated at their ends in mature oocytes and early embryos. This maternal miRNA adenylation is extensively conserved in fly, sea urchin and mouse. The researchers have also identified that the enzyme called 'Wispy' is required to catalyze miRNA adenylation and to reduce miRNA ...

Better focus at the micro world: A low-budget focus stacking system for mass digitization

Better focus at the micro world: A low-budget focus stacking system for mass digitization
2014-12-17
A team of Belgian researchers constructed a focus stacking set-up made of consumer grade products with better end results than high-end solutions and this at only a tenth of the prize of current existing systems. Because of the operational ease, speed and the low cost of the system, it is ideal for mass digitization programs involving type specimens. The study was published in the open-access journal ZooKeys. Enthusiasts or scientists, many struggle to take high quality pictures of the tiny animals of the micro world. When they eventually succeed in their effort, it is ...

Hugs help protect against stress and infection, say Carnegie Mellon researchers

2014-12-17
PITTSBURGH--Instead of an apple, could a hug-a-day keep the doctor away? According to new research from Carnegie Mellon University, that may not be that far-fetched of an idea. Led by Sheldon Cohen, the Robert E. Doherty University Professor of Psychology in CMU's Dietrich College of Humanities and Social Sciences, the researchers tested whether hugs act as a form of social support, protecting stressed people from getting sick. Published in Psychological Science, they found that greater social support and more frequent hugs protected people from the increased susceptibility ...

Substance from broccoli can moderate defects

2014-12-17
This news release is available in German. Most Hutchinson-Gilford Progeria Syndrome (HGPS) patients carry a mutation that produces a defective form of the protein lamin A. This defective protein is referred to as progerin. Normal lamin A is a key component of the matrix surrounding the DNA in the cell nucleus and plays a role in gene expression. By contrast, the defective form, progerin, is not functional but is nevertheless continuously synthesized. The result is that progerin accumulates in the nucleus and causes the cell to "age". Consequently, HGPS patients develop ...

Fine tuning your campaign

2014-12-17
Platform ecosystems are a key focus of the research carried out in the Information Systems & E-Services Group headed by Professor Alexander Benlian in the Law and Economics Department at TU Darmstadt. Ferdinand Thies and Michael Wessel decided to dedicate themselves just over a year ago primarily to the study of crowdfunding - the collective financing of social, creative or commercial projects by a community of internet users. Crowdfunding campaigns generated around five million dollars of investment in 2013 and the market is set to grow further. These types of campaign ...

AAAS analysis shows widespread looting and damage to historical sites in Syria

AAAS analysis shows widespread looting and damage to historical sites in Syria
2014-12-17
Four of six major archaeological sites in Syria have been heavily looted and damaged, according to a AAAS analysis of high-resolution satellite images that documents the extent of the destruction. The report analyzes six of the 12 sites that Syria has nominated as World Heritage Sites: Dura Europos, Ebla, Hama's Waterwheels, Mari, Raqqa, and Ugarit. A forthcoming report will analyze the additional six sites. "As we continue to study the conditions at Syria's important cultural sites, we have observed significant destruction that is largely the result of conflict. However, ...

North Atlantic signalled Ice Age thaw 1,000 years before it happened, reveals new research

2014-12-17
The Atlantic Ocean at mid-depths may have given out early warning signals - 1,000 years in advance - that the last Ice Age was going to end, scientists report today in the journal Paleoceanography. Scientists had previously known that at the end of the last Ice Age, around 14,700 years ago, major changes occurred to the Atlantic Ocean in a period known as the Bolling-Allerod interval. During this period, as glaciers melted and the Earth warmed, the currents of the Atlantic Ocean at its deepest levels changed direction. The researchers have analysed the chemistry of ...

Global carbon dioxide emissions increase to new all-time record, but growth is slowing down

2014-12-17
2013 saw global CO2 emissions from fossil fuel use and cement production reach a new all-time high. This was mainly due to the continuing steady increase in energy use in emerging economies over the past ten years. However, emissions increased at a notably slower rate (2%) than on average in the last ten years (3.8% per year since 2003, excluding the credit crunch years). This slowdown, which began in 2012, signals a further decoupling of global emissions and economic growth, which reflects mainly the lower emissions growth rate of China. China, the USA and the EU remain ...

Not just for the holidays, mistletoe could fight obesity-related liver disease

2014-12-17
Mistletoe hanging in doorways announces that the holidays are just around the corner. For some people, however, the symbolic plant might one day represent more than a kiss at Christmas time: It may mean better liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related liver disease in mice. Their study appears in ACS' Journal of Agricultural and Food Chemistry. Jungkee Kwon and colleagues note that, according to recent research, Korean mistletoe produces a number of biologically active compounds. These ...

Combining social media and behavioral psychology could lead to more HIV testing

2014-12-17
Social media such as Twitter and Facebook can be valuable in the fight against HIV in the United States, where research has demonstrated they can prompt high-risk populations to request at-home testing kits for the virus that causes AIDS, suggesting a way to potentially boost testing rates. But does it lead to actual testing, and can it work outside the United States? A new study from the UCLA Center for Digital Behavior published online Dec. 15 by the peer-reviewed journal Lancet HIV suggests that it can. The study, conducted in Peru among men who have sex with men, ...

Growing shortage of stroke specialists seen

2014-12-17
MAYWOOD, Ill. - Although stroke is the No. 4 cause of death and a leading cause of disability in the United States, there's an increasing shortage of neurologists who specialize in stroke care. In the December issue of the journal Stroke, two prominent neurologists propose a bold program to increase the number of stroke specialists. Their proposals include encouraging more young physicians to specialize in stroke, increasing stroke specialists' pay and opening the subspecialty to physicians who are not neurologists. The authors are Harold P. Adams, Jr., MD of the University ...
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