Washington, DC--Women who experience moderate to severe hot flashes and night sweats during menopause tend to have lower bone mineral density and higher rates of hip fracture than peers who do not have menopausal symptoms, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. Menopause is the life stage when a woman's ovaries stop producing hormones and her menstrual periods stop. About 60 percent of women experience hot flashes, which can last for several years. Postmenopausal women face a greater risk of developing ...

MAYWOOD, Ill. - A drug called ganciclovir is given to lung transplant patients to protect against a life-threatening virus that is common after transplantation. Ganciclovir reduces mortality due to the virus from 34 percent to between 3 and 6 percent. But between 5 percent and 10 percent of patients infected with the virus have strains that are resistant to the drug. A Loyola University Medical Center study found that such resistance may occur more frequently in cystic fibrosis patients. These patients were found to have insufficient levels of the drug in their bloodstream, ...

A group of researchers from the University of Barcelona (Spain), the CNRS in Montpellier (France) and Princeton University (USA) report in The American Naturalist that the vaccination of females of a long-lived seabird species, the Cory's shearwater, results in levels of antibodies that allow their transmission to their offspring for several years and could provide several weeks of protection after hatching to these offspring. Over a period of 6 years, in the Canary Archipelago (Spain), the researchers tracked the immune status of a large number of adults and chicks, ...

VIDEO: Using data from NASA/USGS satellite Landsat 8, scientists have measured how vegetation in the Colorado River Delta has responded to the pulse of water released in March 2014 as part... Click here for more information. A pulse of water released down the lower reaches of the Colorado River last spring resulted in more than a 40 percent increase in green vegetation where the water flowed, as seen by the Landsat 8 satellite. The March 2014 release of water - an experimental ...

Hydrogen fuel is a promising source of clean energy that can be produced by splitting water into hydrogen and oxygen gas. The reaction is difficult but achievable with the help of a catalyst, a material that can speed up the process. However, current catalysts lack the efficiency required for water splitting to be commercially competitive. Recently scientists have identified one such catalyst, iron-doped nickel oxide, as a highly active compound that can speed up this reaction, but the origin of its activity is not well understood. Now researchers at Princeton University ...

The United States is a melting pot of different racial and ethnic groups, but it has not been clear how the genetic ancestry of these populations varies across different geographic regions. In a landmark study published by Cell Press December 18th in the American Journal of Human Genetics, researchers analyzed the genomes of more than 160,000 African Americans, Latinos, and European Americans, providing novel insights into the subtle differences in genetic ancestry across the United States. "Our study not only reveals the historical underpinnings of regional differences ...

It's no secret that people are judgmental, and young children are no exception. When children witness "good" or "bad" behavior, their brains show an immediate emotional response. But, according to a study appearing in the Cell Press journal Current Biology on December 18, it takes more than that kind of automatic moral evaluation for kids to act with generosity and share their stickers. By recording kids' brain activity, the study found that generous behavior requires a controlled thought process. The neurodevelopmental findings are the first to link implicit moral evaluations ...

Golden-winged warblers apparently knew in advance that a storm that would spawn 84 confirmed tornadoes and kill at least 35 people last spring was coming, according to a report in the Cell Press journal Current Biology on December 18. The birds left the scene well before devastating supercell storms blew in. The discovery was made quite by accident while researchers were testing whether the warblers, which weigh "less than two nickels," could carry geolocators on their backs. It turns out they can, and much more. With a big storm brewing, the birds took off from their ...

Many recent studies showed that calorie restrictions reduce the incidence of cancer, whereas high-calorie diets cause obesity and diabetes, both of which increase the risk of developing cancers. However, tumor biology still hides complex mechanisms, as revealed by researchers from the Faculty of Medicine of the University of Geneva (UNIGE), Switzerland. In a study published in Cell Metabolism, scientists not only found the unexpected benefit that a change of diet had on certain types of lung cancer, they also deciphered the molecular mechanism underlying this dietary effect ...

Berkeley -- When birds unexpectedly flee their nesting grounds, it may be a demonstration of Mother Nature's early-warning system that a massive storm is approaching. While tracking a population of golden-winged warblers, a research team led by ecologist Henry Streby at the University of California, Berkeley, discovered that birds in the mountains of eastern Tennessee fled their breeding grounds one to two days ahead of the arrival of powerful supercell storms. The storm system swept through the central and southern United States in late April 2014, generating 84 confirmed ...

This news release is available in Japanese. Behind all motor, sensory and memory functions, calcium ions are in the brain, making those functions possible. Yet neuroscientists do not entirely understand how fast calcium ions reach their targets inside neurons, and how that timing changes neural signaling. Researchers at the Okinawa Institute of Science and Technology Graduate University have determined how the distance from calcium channels to calcium sensors on vesicles affects a neuron's signaling precision and efficacy. In international collaboration with research ...

Climate change impacts will require major but very uncertain transformations of global agriculture systems by mid-century, according to new research from the International Institute for Applied Systems Analysis. Climate change will require major transformations in agricultural systems, including increased irrigation and moving production from one region to another, according to the new study, published in the journal Environmental Research Letters. However without careful planning for uncertain climate impacts, the chances of getting adaptation wrong are high, the study ...

PASADENA, Calif., December 18, 2014 -- Self-reported moderate to vigorous exercise was associated with lower blood pressure and blood glucose levels in a Kaiser Permanente study published in the journal Preventing Chronic Disease. Data collected from Kaiser Permanente's Exercise as a Vital Sign (EVS) program, in which medical office staff asks patients about their exercise habits at every health care visit, revealed associations between moderate to vigorous exercise and improved measures of cardiometabolic health for both men and women. Few previous studies have examined ...

The part of the brain that tells us the direction to travel when we navigate has been identified by UCL scientists, and the strength of its signal predicts how well people can navigate. It has long been known that some people are better at navigating than others, but until now it has been unclear why. The latest study, funded by the Wellcome Trust and published in Current Biology, shows that the strength and reliability of 'homing signals' in the human brain vary among people and can predict navigational ability. In order to successfully navigate to a destination, you ...

VIDEO: Research from Univ. of Iowa and Russian scientists show crows are capable of executive-level thinking. Click here for more information. Crows have long been heralded for their high intelligence - they can remember faces, use tools and communicate in sophisticated ways. But a newly published study finds crows also have the brain power to solve higher-order, relational-matching tasks, and they can do so spontaneously. That means crows join humans, apes and monkeys in exhibiting ...

TORONTO -- Very small segments of genes called "microexons" influence how proteins interact with each other in the nervous system, scientists at the University of Toronto have found, opening up a new line of research into the cause of autism. The researchers found that microexons are used in neurons by alternative splicing, a process in which a single gene can produce many different proteins. Microexons are pasted -- or spliced -- into gene messengers (mRNAs) to generate forms of proteins that the nervous system needs to function properly. Misregulation of this process, ...

RESEARCHERS have discovered the unique genetic paths that the childhood brain tumour medulloblastoma follows when the disease comes back, according to research* published in Cancer Cell today (Thursday). The study - funded by Cancer Research UK, Action Medical Research and others** - shows that taking an extra tumour sample at recurrence, when there are no effective therapies, could identify subsets of patients that might be treatable with existing drugs that target the genetic faults. The scientists, based at Newcastle University and The Institute of Cancer Research ...

There are two main families of bacteria : those that are surrounded by a single membrane (or one outer wall) and those that are surrounded by two membranes (or two outer walls). The team of Jean-François Collet, professor at the de Duve Institute at UCL, looked at this second type of bacteria. For a bacterium to survive, it has to keep its two outer walls intact. If one of these walls is damaged, the bacterium dies. So it was vital for the UCL researchers to analyse the protection mechanisms of these bacterial "walls' (to find their weak spot), so as to be able to ...

This latest research by Joshua Brickman and his research team from Danish Stem Cell Center (Danstem) at the University of Copenhagen specifically found that inhibiting or blocking stem cells ability to make a specific decision, leads to better cell growth and could lead to defined ways to differentiate stem cells. This research is the first comprehensive analysis of a pathway important for stem and cancer cell decisions known as Erk. As a result this work could contain clues to cancer treatment as well as helping to establish a platform to make stem cell treatments for ...

After an incomplete spinal cord injury, the body can partially recover basic motor function. So-called muscle spindles and associated sensory circuits back to the spinal cord promote the establishment of novel neuronal connections after injury. This circuit-level mechanism behind the process of motor recovery was elucidated by Prof. Silvia Arber's research group at the Biozentrum, University of Basel and the Friedrich Miescher Institute for Biomedical Research. Their findings may contribute to designing novel strategies for treatment after spinal cord injuries and have ...

Walter and Eliza Hall Institute researchers have for the first time revealed how dying cells are hidden from the immune 'police' that patrol the body. The research answers a decades-old mystery about the death of cells, which in some situations can alert the immune system to potential danger, but in other circumstances occurs 'silently', unnoticed by immune cells. Silent cell death, or apoptosis, is a controlled way for the body to eliminate cells that may be damaged, old, or surplus to the body's requirements, without causing collateral damage. This 'normal' cell death ...

This news release is available in Spanish. The genome is the cell's book of instructions. All the cells in our body contain the same genomic information but each of them "reads" the gene fragments that interest them in order to carry out their function. So, neurones, hepatocytes and cardiac cells are different although their genome is the same. In order to achieve this huge variety of functions from the same genome, the cells employ a mechanism known as alternative splicing. This enables them to combine several fragments - known as exons - from the same genes in order ...

Mountain View, Calif. - December 18, 2014 - 23andMe, Inc., the leading personal genetics company, today announced the publication of a study that pinpoints fine-scale differences in genetic ancestry of individuals from across the United States. Since immigrants first arrived more than four hundred years ago, the United States has served as a meeting place for peoples from different continents. This study illuminates how American history and the ongoing mixing of peoples with African, European, and American origins can be seen in our DNA. "The relationship between genomics ...

HOUSTON - (Dec. 18, 2014) - Cars that run on natural gas are touted as efficient and environmentally friendly, but getting enough gas onboard to make them practical is a hurdle. A new study led by researchers at Rice University promises to help. Rather than shoehorn bulky high-pressure tanks like those used in buses and trucks into light vehicles, the Department of Energy (DOE) encourages scientists to look at new materials that can store compressed natural gas (CNG) at low pressure and at room temperature. Cage-like synthetic macromolecules called metal organic frameworks ...

LA JOLLA, CA--December 18, 2014--Collaborating scientists from The Scripps Research Institute (TSRI) and the University of California (UC) San Diego have developed a powerful new system for studying how proteins and other biological molecules form and lose their natural folded structures. Using the new system, researchers can force a sample of molecules to unfold and refold by boosting and then dropping the temperature, so quickly that even some of the fastest molecular folding events can be tracked. "One way of studying these structures has been to make them unfold ...