Growing cities tend to run out of land for waste management and new landfill sites. Artificial Intelligence can help city managers create more powerful long-term forecasts of solid waste volumes and landfill requirements, even with missing or inaccurate data. UJ researchers found that a 10-neuron model produced the best 30-year forecast for municipal solid waste in a growing city. All over the world, large cities are running out of space for municipal solid waste. Existing landfill sites are rapidly filling up and no-one wants a new site anywhere near their homes or businesses. Meanwhile, taxpayers aren't interested in higher costs for quality waste management either. One way of significantly extending ...

Groundbreaking research from the University of South Australia has delivered world-first national-level guidelines to better inform children's physical activity and screen time in Outside School Hours Care (OSHC). Developed with input from the OSHC sector, the guidelines aim to address growing concerns of children's sedentary behaviour marked by an increase in regular screen time. Research shows that 31-79 per cent of OSHC sessions are sedentary. The guidelines specifically encourage energetic play while discouraging screen use: Before School Care should schedule 45 minutes of physical activities and no more ...

Arctic habitats have fascinated biologists for centuries. Their species-poor insect faunas, however, provide little reward for entomologists - scientists who study insects - to justify spending several weeks or even months in the hostile environments of tundra or polar deserts. As a result, data on insects from the High Arctic islands are often based on occasional collecting and remain scarce. Vize Island, located in the northern part of the Kara Sea, is one of the least studied islands of the Russian High Arctic in terms of its biota. Scientists Dr Maria V. Gavrilo of the Arctic ...

WATERLOO, Ontario, March 29, 2021--A newly-published paper represents one of the most comprehensive reviews of advancements to come in contact lenses, catapulting the commonly-used medical device to applications well beyond refractive error correction. Contact Lens Technologies of the Future (Jones L, et al.) is now in press from Contact Lens and Anterior Eye, the peer review journal of the British Contact Lens Association (BCLA). It joins nine other papers being printed in next month's special edition as part of the BCLA-led Contact Lens Evidence-based Academic Reports (CLEAR) series. "There are a range of ...

Bioengineering researchers at Lehigh University have identified a previously unknown interaction between receptors in human cells and the spike, or "S," protein of SARS-CoV-2, the virus that causes COVID-19. This new information could aid in the development of new strategies to block SARS-CoV-2 entry into human cells. X. Frank Zhang and Wonpil Im knew from recent studies that the interaction between the SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) receptors in human cells is stronger than the interaction between the structurally identical spike protein of SARS-CoV-1, the virus that caused the 2002-2004 SARS outbreak, and the same receptors. "Our goal was to characterize SARS-CoV-2 ...

CHAMPAIGN, Ill. -- Monitoring the progression of multiple sclerosis-related gait issues can be challenging in adults over 50 years old, requiring a clinician to differentiate between problems related to MS and other age-related issues. To address this problem, researchers are integrating gait data and machine learning to advance the tools used to monitor and predict disease progression. A new study of this approach led by University of Illinois Urbana Champaign graduate student Rachneet Kaur, kinesiology and community health professor Manuel Hernandez and industrial ...

United Methodist churches -- whether the congregation is white or not -- have higher attendance when located within white neighborhoods. But racial diversity within a church is associated with higher average attendance over time, according to a new study. "This is a startling contrast to previous research that reported multiracial congregations are less stable," said lead author Kevin D. Dougherty, Ph.D., associate professor of sociology at Baylor University. The study is published in the journal Social Forces. Previous research has found that it is difficult for congregations to build and sustain racially diverse memberships, ...

A new study suggests that clearing the invasive woody weed Prosopis julifora and grassland restoration in Baringo County, Kenya, may have significant financial benefits for local stakeholders and contribute to climate change mitigation. Climate change, land degradation, and invasive alien species (IAS) such as Prosopis julifora are major threats to people's livelihoods in arid and semi-arid areas with each of these having negative impacts on ecosystem services - including vegetation biomass, which is a prime resource for pastoralists and agro-pastoralists. The team, comprising PhD students and established scientists from four countries and different ...

LOS ALAMOS, N.M., March 26, 2021--New research has demonstrated that a magnetic uranium compound can have strong thermoelectric properties, generating four times the transverse voltage from heat than the previous record in a cobalt-manganese-gallium compound. The result unlocks a new potential for the actinide elements at the bottom of the periodic table and point to a fresh direction in research on topological quantum materials. "We found that the large spin-orbit coupling and strong electronic correlations in a system of uranium-cobalt-aluminum doped with ruthenium resulted in a colossal anomalous Nernst conductivity," said Filip Ronning, lead investigator on the paper published today in Science Advances. Ronning ...

Presents a brief overview of the eight COVID-19 editorials published in DMPHP over the past year and using them as a framework to follow the evolution of the Pandemic over time. A review of the salient epidemiological and clinical dimensions of COVID-19 over time is given as well as a discussion of the medical and public health impacts of the disease and the interventions and policies put in place to contain and mediate the virus. The concluding discussion questions the validity of the criteria used in selection of priority groups for vaccination in the US and notes that had a uniform program supporting the immunization of all over age 65 (accounting for 80% ...

How do different parts of the body communicate? Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain. The team studied fruit flies and cutting-edge brain cell models called organoids. They focused on the signals muscles send when stressed. The researchers found that stress signals rely on an enzyme called Amyrel amylase and its product, the disaccharide maltose. The scientists showed that mimicking the stress signals can protect the brain and retina from aging. The signals work by preventing the buildup of misfolded protein aggregates. Findings suggest that tailoring this signaling may potentially help combat neurodegenerative conditions like age-related dementia and Alzheimer's disease. "We found that a stress response ...

The Environmental Protection Agency (EPA) is underestimating methane emissions from oil and gas production in its annual Inventory of U.S. Greenhouse Gas Emissions and Sinks, according to new research from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS). The research team found 90 percent higher emissions from oil production and 50 percent higher emissions for natural gas production than EPA estimated in its latest inventory. The paper is published in the journal Atmospheric Chemistry and Physics. The research team, led by Joannes Maasakkers, a former graduate student at SEAS, developed a method to trace and map ...

Australian researchers have discovered a new way to target an aggressive childhood cancer, neuroblastoma, one of the most common and dangerous cancers in young children. The discovery may also have important implications for some other aggressive cancers in children, including certain brain tumours, as well as some adult cancers, including ovarian and prostate cancer. The new research, led by scientists at Children's Cancer Institute and published in Nature Communications, has discovered that a cellular protein called ALYREF plays a crucial role in accelerating the effects of the cancer driver gene, MYCN, in neuroblastoma. Scientists have known for some time that the one third of children with neuroblastoma who have ...

Tumor targeting and intratumoral penetration are long-standing issues for cancer therapeutics. Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and the University of Chinese Academy of Sciences (UCAS) have developed a new platelet-based formulation which demonstrated potent therapeutic effects against cancer in murine models. The scientists utilized the aggregation and activation features of the platelets to address issues of tumor targeting and intratumoral penetration. Upon carrying photothermal nanoparticles and immunostimulators, this biomimetic formulation also achieves an efficient combination therapy against multiple types of cancer. This study was published in Science Advances on March 26. Recently, photothermal ...

One million species are under threat of extinction worldwide, primarily due to adverse human impact. The loss of a species is an ethical tragedy, but additionally, it can have dramatic effects on the functioning of ecosystems on Earth. In each ecosystem, species have their roles, just like actors do in a play. These roles depend on the characteristics of the species, like their size, weight, shape, reproductive capacity, or the food resources they use. If some species are similar, they can sometimes substitute each other and keep the ecosystem going even if one of them is lost. However, the accumulated ...

For people with tooth decay, drinking a cold beverage can be agony. "It's a unique kind of pain," says David Clapham, vice president and chief scientific officer of the Howard Hughes Medical Institute (HHMI). "It's just excruciating." Now, he and an international team of scientists have figured out how teeth sense the cold and pinpointed the molecular and cellular players involved. In both mice and humans, tooth cells called odontoblasts contain cold-sensitive proteins that detect temperature drops, the team reports March 26, 2021, in the journal Science Advances. Signals from these cells can ultimately trigger a jolt of pain to the brain. The work offers an explanation for how one ...

Because of their interactions and conflicts with the major contemporaneous civilizations of Eurasia, the Scythians enjoy a legendary status in historiography and popular culture. The Scythians had major influences on the cultures of their powerful neighbors, spreading new technologies such as saddles and other improvements for horse riding. The ancient Greek, Roman, Persian and Chinese empires all left a multitude of sources describing, from their perspectives, the customs and practices of the feared horse warriors that came from the interior lands of Eurasia. Still, despite evidence from external sources, little is known about Scythian history. Without a written ...

'A persistent and troubling rural disadvantage' Strategies needed to support rural Americans CHICAGO ---Heart failure deaths are persistently higher in rural areas of the United States compared with urban areas, reports a new Northwestern Medicine study. The research also showed race disparities in heart failure are prevalent in rural and urban areas with greatest increases among Black adults under 65 years old. Heart failure deaths have been increasing nationally since 2011, but there is significant geographic variation in these patterns based on race. "This work demonstrates a persistent and troubling rural disadvantage with significantly higher rates of death in rural areas compared with urban areas," said lead study author Dr. Sadiya ...

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2--the virus that causes COVID-19 - and then used an FDA-approved cancer drug to blunt the viral protein's detrimental effects. In their experiments in fruit flies and human cell lines, the team discovered the cell process that the virus hijacks, illuminating new potential candidate drugs that could be tested for treating severe COVID-19 disease patients. Their findings were published in two studies simultaneously on March XX in Cell & Bioscience, a Springer Nature journal. "Our work suggests there is a way to prevent SARS-COV-2 from injuring the body's tissues and doing extensive damage," says senior author of ...

Using electricity to split water into hydrogen and oxygen can be an effective way to produce clean-burning hydrogen fuel, with further benefits if that electricity is generated from renewable energy sources. But as water-splitting technologies improve, often using porous electrode materials to provide greater surface areas for electrochemical reactions, their efficiency is often limited by the formation of bubbles that can block or clog the reactive surfaces. Now, a study at MIT has for the first time analyzed and quantified how bubbles form on these porous electrodes. The researchers have found that there are three different ways bubbles can form on and depart from the surface, and that these can be precisely controlled ...

Limerick, Ireland, 26 March 2020: Researchers at Lero, the Science Foundation Ireland Research Centre for Software and University of Limerick (UL), have found video gamers can significantly improve their esport skills by training for just 10 minutes a day. The research team at Lero's Esports Science Research Lab (ESRL) at UL also found novice gamers benefited most when they wore a custom headset delivering transcranial Direct Current Stimulation (tDCS) for 20 minutes before training sessions. Dr Mark Campbell, director of Lero's Esports Science Research Lab (ESRL) and senior lecturer in sports psychology at UL, said their work showed that neurostimulation could accelerate motor performance improvements specifically in novice esports ...

Patients with lupus are more likely to have metabolic syndrome and insulin resistance - both factors linked to heart disease - if they have lower vitamin D levels, a new study reveals. Researchers believe that boosting vitamin D levels may improve control of these cardiovascular risk factors, as well as improving long-term outcomes for patients with systemic lupus erythematosus (SLE). Given that photosensitivity is a key feature of SLE, the scientists say that a combination of avoiding the sun, using high-factor sunblock and living in more northerly ...

What The Study Did: Insurance claims were used to assess patterns of telehealth use across surgical specialties before and during the COVID-19 pandemic. Authors: Grace F.Chao, M.D., M.Sc., of the National Clinician Scholars Program at the University of Michigan and Veterans Affairs Ann Arbor in Michigan, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamasurg.2021.0979) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions ...

What The Study Did: This article discusses possible pathogenic mechanisms of brain dysfunction in patients with COVID-19. Authors: Maura Boldrini, M.D., Ph.D., of the New York State Psychiatric Institute, Columbia University Irving Medical Center in New York, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapsychiatry.2021.0500) Editor's Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial ...

Bariatric surgery can significantly reduce the risk of cancer--and especially obesity-related cancers--by as much as half in certain individuals, according to a study by researchers at Rutgers Robert Wood Johnson Medical School's Center for Liver Diseases and Liver Masses. The research, published in the journal Gastroenterology, is the first to show bariatric surgery significantly decreases the risk of cancer in individuals with severe obesity and nonalcoholic fatty liver disease (NAFLD). The risk reduction is even more pronounced in individuals with NAFLD-cirrhosis, the researchers say. "We knew that obesity leads to certain problems, including cancer, but no one ...