Sickle cell disease is the most prevalent inherited blood disorder in the world, affecting 70,000 to 100,000 Americans. However, it is considered an orphan disease, meaning it impacts less than 200,000 people nationally, and is therefore underrepresented in therapeutic research. A team led by Abhishek Jain from the Department of Biomedical Engineering at Texas A&M University is working to address this disease. "I'm trying to create these new types of disease models that can impact health care, with the long-term goal of emphasizing on applying these tools ...

> CATONSVILLE, MD, March 24, 2021 - COVID-19 has been shown to spread on airplanes by infected passengers, so minimizing the risk of secondary infections aboard aircraft may save lives. New research in the INFORMS journal Service Science uses two models to help solve the airplane seating assignment problem (ASAP). The models can lower the transmission risk of COVID-19 more so than the strategy of blocking the middle seats, given the same number of passengers. "Blocking the middle seat on an airplane may provide limited benefit in reducing the risk of transmission of COVID-19. Rather, other health protocols are better supported at preventing the transmission ...

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, arrived one year ago and turned our lives upside-down. While worldwide vaccination programs are currently ongoing, we do not yet know for how long the vaccine will provide immune protection against infection, and if the currently approved vaccines can provide protection against the emerging virus variants. In addition, it appears that vaccines cannot prevent illness for people who have already been infected. In contrast to vaccines, there are currently no effective drugs that act against the virus SARS-CoV-2. New research by Associate Professor Jasmin Mecinovic and co-workers from the Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, now presents a compound that might provide a basis for the ...

Decarbonizing the economy and achieving the transition from fossil fuels to renewable energies is one of the most urgent global challenges of the 21st century. Hydrogen can play a key role in this process as a promising climate-neutral energy vehicle. Yet, the so-called green hydrogen economy requires that hydrogen production be based exclusively on renewable energy. In addition, it should ideally not use expensive and rare metal catalysts, whose production has severe environmental consequences. To address this challenge, ITQB NOVA researchers Inês Cardoso Pereira and Mónica Martins are working on an innovative technology to produce hydrogen from light using non-photosynthetic microorganisms. Hydrogen offers exciting new possibilities as an energy vehicle, ...

The Event Horizon Telescope (EHT) collaboration, a multinational team of over 300 scientists including two astrophysicists from the University of the Witwatersrand (Wits University), has revealed today a new view of the massive object at the centre of the M87 galaxy: how it looks in polarised light. This is the first time astronomers have been able to measure polarisation, a signature of magnetic fields, this close to the edge of a black hole. The observations are key to explaining how the M87 galaxy, located 55 million light-years away, is able to launch energetic jets from its core. "We are now seeing the next crucial piece of evidence to understand how magnetic fields behave around black holes, and how activity in this very compact region of space can drive powerful ...

The Event Horizon Telescope (EHT) collaboration, who produced the first ever image of a black hole, has today revealed a new view of the massive object at the centre of the Messier 87 (M87) galaxy: how it looks in polarised light. This is the first time astronomers have been able to measure polarisation, a signature of magnetic fields, this close to the edge of a black hole. The observations are key to explaining how the M87 galaxy, located 55 million light-years away, is able to launch energetic jets from its core. "We are now seeing the next crucial piece of evidence to understand ...

A new study from the University of Bergen (UiB) shows that the way young people view their bodies have a great impact on their BMI. In a two-year follow up study among 1225 Norwegian adolescents in their early teens, professor Eivind Meland and his team examined how body mass index, self-esteem and self-rated health were mutually impacted and influenced by body dissatisfaction. "We revealed that positive self-image and self-esteem protected against weight gain", professor emeritus Meland says. The girls had in general lower body confidence than boys, the study shows. Body dissatisfaction The eager to be thinner, dieting, and wanting to change something with the body all impaired self-rated health ...

A new study shows that when people replace their old couch with a new one that has no added flame retardants, levels of the harmful chemicals in household dust drop significantly. Replacing the foam inside the couch cushions is also just as effective. The findings confirm that choosing healthier furniture without flame retardants can make a big difference in people's--especially children's--everyday exposures to these toxic chemicals. "We've long suspected that couches are a major source of toxic chemicals in dust. Now, for the first time, we have evidence demonstrating the positive impacts of replacing old furniture containing flame retardants," ...

What is the world made of? This question, which goes back millennia, was revisited by theoretical physicist Steven Weinberg from the University of Texas in Austin, TX, USA in the first of an international seminar series, 'All Things EFT'. Weinberg's seminar has now been published as an article in the journal EPJ H. And Weinberg is well placed to discuss both Effective Field Theories (EFTs) and the nature of the Universe, as he shared the 1979 Nobel Prize for Physics for developing a theory to unify the weak and electromagnetic interactions between elementary particles. This fed into the development of the ...

Ruptures of the carotid artery (cervical artery dissection) are the most common cause of stroke in people under 50 years of age, with an annual incidence of 2-3 cases per 100,000 persons. Salicylic-acid preparations (acetylsalicylic acid: aspirin, Aspegic) and blood-thinning medication (anticoagulants) are used for treatment. The multicenter therapy study "Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection (TREAT-CAD, NCT02046460)" investigated whether dissections - tears in the wall of vessels supplying blood to the brain - can be treated with aspirin or whether more complex blood thinning (anticoagulation) ...

Copepods are tiny crustaceans about the size of a grain of rice, but they are one of the most important parts of the Earth's aquatic ecosystems. Their behavior and interaction with the environment, however, remains a relative mystery. Now, a recent paper published in the Journal of Experimental Biology sheds new light on how these miniature marvels move and cluster in the ocean. Researchers from Bigelow Laboratory of Ocean Sciences and the Georgia Institute of Technology found that the copepods gather around small vortexes in the ocean, a finding which could have significant implications for the food web. "We're getting at a mechanism that helps us understand how the ecosystem ...

Chemists from RUDN University found out that fluorine and fluoroalkyl groups increase the efficiency of catalysts in metathesis reactions that are used in the pharmaceutical industry and polymer chemistry. The team also identified fluorine-containing compounds that can simplify the purification of the catalyst from the reaction product, making it reusable. The results of the study were published in the Russian Chemical Reviews journal. Many medicinal drugs and polymers are based on olefins, organic compounds with a double bond between carbon atoms. To obtain useful substances from them, scientists used the metathesis reaction. In the course of metathesis, ...

New research from the University of Kent and Leeds Beckett University has found that feelings of shame and stigmatisation at the idea of contracting Covid-19 are linked to lower compliance of social distancing and the likelihood of reporting infection to authorities and potential contacts in Italy, South Korea and the USA. In contrast, the study found that individuals who trust their Government's response to the Covid-19 pandemic and feel a mutual solidarity are more likely to report Covid-19 contraction to authorities and acquaintances. In Italy and South Korea, individuals are also more likely to follow social distancing regulations if they trust their Government's response to the pandemic, while in the USA, trust does not lead to social distancing compliance. This could ...

The invisibility of dads who lose access to their children because of concerns about child neglect or their ability to provide safe care comes under the spotlight in new research. A research partnership between the University of East Anglia and Lancaster University provides new evidence ('Up Against It': Understanding Fathers' Repeat Appearance in Local Authority Care Proceedings) about fathers' involvement in care and recurrent care proceedings in England. A national conference today (Wednesday 24th March), co-hosted online by the two universities, will share key insights from this study, funded by the Nuffield ...

Skoltech researchers examined the antibiotic compounds that employ a 'Trojan horse' strategy to get into a bacterial cell unrecognized and prevent the synthesis of proteins, ultimately killing the cell. They were able to identify new gene clusters that look like those of known 'Trojan horses' - these likely guide the biosynthesis of new antimicrobials that require further investigation. The review paper was published in the journal RSC Chemical Biology. When it comes to antimicrobial attacks, the most difficult thing is breaching the formidable outer defenses: getting inside a target cell to deploy the deadly weapon can be tricky. A number of antimicrobial compounds employ the well-known 'Trojan horse' strategy: they present themselves to a cell ...

During this unique study researchers from the University of Surrey and European Food Information Council (EUFIC) reviewed over 100 scientific papers to examine if different criteria exist in developing classification systems for processed foods and, if so, what distinguishes them. Classification systems that categorise foods according to their "level of processing" have been used to predict diet quality and health outcomes, inform guidelines and in product development. Researchers found that most classification system's criteria are not aligned with existing scientific evidence on nutrition and food processing. It is thought that this may stem from different perspectives and intentions behind the development of some classification systems. Researchers also noted a failure ...

A new study from the University of Kent's School of Anthropology and Conservation has found that Oldowan and Acheulean stone tool technologies are likely to be tens of thousands of years older than current evidence suggests. They are currently the two oldest, well-documented stone tool technologies known to archaeologists. These findings, published by the Journal of Human Evolution, provide a new chronological foundation from which to understand the production of stone tool technologies by our early ancestors. They also widen the time frame within which to discuss the evolution of human technological capabilities and associated dietary and behavioural shifts. For the study, a team led by Kent's Dr Alastair Key and Dr David Roberts, alongside Dr Ivan Jaric from the Biology ...

BEER-SHEVA, Israel...March 24, 2021 - Surprisingly, exposure to a high background radiation might actually lead to clear beneficial health effects in humans, according to Ben-Gurion University of the Negev and Nuclear Research Center Negev (NRCN) scientists. This is the first large-scale study which examines the two major sources of background radiation (terrestrial radiation and cosmic radiation), covering the entire U.S. population. The study's findings were recently published in Biogerontology. Background radiation is an ionizing radiation that exists ...

Ahead of the first U.S. emergency use authorization for a COVID-19 vaccine, only half of Americans said they were likely to get vaccinated as soon as possible, according to an in-depth study led by researchers at the Johns Hopkins Bloomberg School of Public Health. The researchers conducted an online survey of 2,525 Americans in a two-week period from late November to early December, asking them about their intentions regarding COVID-19 vaccination as well as other values and beliefs. About 50 percent responded that they intended to get vaccinated as soon as possible. About 10 percent said they intended not to be vaccinated at all. The remaining 40 percent replied that they probably wouldn't be vaccinated, or probably would be but not as soon as possible. The findings ...

"Based on field experiments with increased carbon dioxide concentration, artificial warming, and modified water supply, scientists understand quite well how future climate change will affect grassland vegetation. Such knowledge is largely missing for effects that already occurred in the last century," says Hans Schnyder, Professor of Grassland at the TUM. Based on the Park Grass Experiment at Rothamsted, researchers have now shown that future predicted effects of climate change on the nutrient status of grassland vegetation have already taken hold in the last century. Plant intrinsic mechanisms respond to CO2 increase Since 1856, research at Rothamsted has been testing the effects of different fertilizer applications on yield performance ...

A new view of the region closest to the supermassive black hole at the center of the galaxy Messier 87 (M87) has shown important details of the magnetic fields close to the black hole and hints about how powerful jets of material can originate in that region. A worldwide team of astronomers using the Event Horizon Telescope, a collection of eight telescopes, including the Atacama Large Millimeter/submillimeter Array (ALMA) in Chile, measured a signature of magnetic fields -- called polarization -- around the black hole. Polarization is the orientation of the electric fields in light and radio waves and it can ...

It all started when litter researchers found a perch in the canals of Leiden that had become caught up in a latex glove. As far as we know, this was the first Dutch victim of corona waste. Since then, they have been trying to obtain an overall picture of the consequences of the corona waste mountain on animals. Biologists Auke-Florian Hiemstra from Naturalis Biodiversity Center and Liselotte Rambonnet from Leiden University started a quest to determine how often and where interactions between corona waste and animals occur. They collected observations from Brazil to Malaysia and from social media to local newspapers and international news websites. A fox in the United Kingdom, birds in Canada, hedgehogs, ...

Neurodevelopmental disorders like autism and schizophrenia disproportionately affect males and are directly linked to early life adversity caused by maternal stress and other factors, which might be impacted by nutrition. But the underlying reasons for these male-specific impacts are not well understood. Researchers from the University of Missouri School of Medicine and the MU Thompson Center for Autism and Neurodevelopmental Disorders have uncovered possible reasons for male vulnerability in the womb, and they've learned a specific maternal dietary supplement called docosahexanoic acid (DHA) may guard against the impact of maternal stress on unborn males during early development. "We believe differences in metabolic requirements for male ...

The more colorful a food, the more nutritious it probably is. For example, purple corn contains compounds associated with a reduced risk of developing diabetes and heart disease. The cobs contain the same compounds but are typically thrown out. Now, researchers report a step-wise biorefinery approach in ACS Sustainable Chemistry & Engineering that uses the whole cob, producing a dye and a possible nutraceutical with the pigments, and an animal litter with the left-overs. Eating a rainbow of fruits and vegetables provides a variety of health benefits, with vitamins and nutrients ...

Since the early industrial revolution in the mid-1700s, fossil fuels have acquired an ever-growing footprint in energy production. However, the environmental concerns of fossil fuels use and their inevitable depletion have led to a global shift toward renewable energy sources. These transitions, however, raise questions about the best choice of renewables and the impact of investing in these resources on consumer cost. In a recent study published in the journal Nature Communications, researchers at Texas A&M University have devised a metric that reflects the average price of energy in ...