Fertility concerns impact breast cancer treatment decisions
2015-08-24
ANN ARBOR, Mich. -- Concerns about fertility kept a third of young women with breast cancer from taking tamoxifen, despite its known benefit in reducing the risk of breast cancer coming back.
In addition, the study found fertility concerns led a quarter of women who started tamoxifen to stop taking it before the recommended treatment period ended.
"Our study points toward the importance of fertility to young breast cancer patients. We need to find a way to bridge the gap between this patient survivorship goal and our concerns as physicians to facilitate the best treatment ...
Electronic trigger reduces delays in evaluation for cancer diagnosis
2015-08-24
HOUSTON - (Aug. 24, 2015) - Electronic triggers designed to search for key data, developed by researchers at Baylor College of Medicine and Michael E. DeBakey Veterans Affairs Medical Center, were able to identify and reduce follow-up delays for patients being evaluated for a diagnosis of colon or prostate cancer.
The full study can be found in the Journal of Clinical Oncology.
"Our computerized triggers scanned huge amounts of patient data in the electronic health record and flagged individuals at risk for delays in follow-up of cancer-related abnormal clinical findings," ...
Danny the 'degenerate' followed by 2 lows
2015-08-24
Danny has become a degenerate, that is, the tropical depression weakened. Satellite and Hurricane Hunter aircraft data showed that Danny degenerated into an elongated area of low pressure near the Windward Islands during the afternoon (local time) on August 24. Meanwhile two other developing low pressure areas lie to the east of Danny.
Satellite data from NOAA's GOES-East satellite at 14:45 UTC (10:45 a.m. EDT) on August 24, showed Danny had become stretched out into a trough of low pressure. At 11 a.m. EDT (1500 UTC), the remnants of Danny were located near latitude ...
FSU researcher identifies protein with promise for cancer therapy
2015-08-24
TALLAHASSEE, Fla. -- In the second part of his lab's recent one-two punch, Florida State University researcher Daniel Kaplan said he has solved a cell division mystery in a way that will intrigue the makers of cancer-fighting drugs.
The key, said Kaplan, a College of Medicine Department of Biomedical Sciences researcher, is a protein called Treslin.
"It can target cancer cells," he said. "Most chemotherapy also targets rapidly dividing normal cells, but this seems to have promise for not doing that. Drug companies are going to be excited."
Before cells can divide, ...
Low awareness of services, perceptions of support continue in UO campus sex climate
2015-08-24
SAN DIEGO, Calif. -- (Aug. 24, 2015) -- A new survey on sexual victimization issues at the University of Oregon reaffirms previous findings that there is a need to increase awareness about available services, while decreasing negative perceptions of institutional support.
Psychology professor Jennifer Freyd provided preliminary findings of the UO survey at the 20th International Summit & Training on Violence, Abuse & Trauma during a keynote session on "Campus Sexual Assault: Current Research and Prevention Approaches."
New issues also surfaced among the key findings ...
Tiny antibodies point to vulnerability in disease-causing parasites
2015-08-24
CAMBRIDGE, Mass. (August 24, 2015) - By teasing apart the structure of an enzyme vital to the infectious behavior of the parasites that cause toxoplasmosis and malaria, Whitehead Institute scientists have identified a potentially 'drugable' target that could prevent parasites from entering and exiting host cells.
Although toxoplasmosis causes disease only in certain individuals-including immunocompromised patients, pregnant women, and their infants, the T. gondii parasite is closely related to Plasmodium, which causes malaria. Research on T. gondii can provide insights ...
Antidepressants fine-tune brain reward pathway to lessen neuropathic pain
2015-08-24
Commonly used antidepressant drugs change levels of a key signaling protein in the brain region that processes both pain and mood, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published August 24 in the Proceedings of the National Academy of Sciences (PNAS). The newly understood mechanism could yield insights into more precise future treatments for nerve pain and depression.
The study was conducted in mice suffering from chronic neuropathic pain, a condition which is caused in mice and humans by nerve damage. Chronic neuropathic ...
UMD-led study identifies the off switch for biofilm formation
2015-08-24
Bacteria are best known as free-living single cells, but in reality their lives are much more complex. To survive in harsh environments, many species of bacteria will band together and form a biofilm--a collection of cells held together by a tough web of fibers that offers protection from all manner of threats, including antibiotics. A familiar biofilm is the dental plaque that forms on teeth between brushings, but biofilms can form almost anywhere given the right conditions.
Biofilms are a huge problem in the health care industry. When disease-causing bacteria establish ...
Personal clothing may spread respiratory infections within the NICU
2015-08-24
Atlanta, GA - August 24, 2015 - Respiratory syncytial virus (RSV), which is the leading cause of childhood respiratory hospitalizations among premature babies, can be detected from the clothes worn by caregivers/visitors who are visiting infants in the neonatal intensive care unit (NICU), according to research being presented at the International Conference on Emerging and Infectious Diseases in Atlanta, Georgia.
"The aim of this study was to identify potential sources of transmission of RSV in the NICU to better inform infection control strategies," said Dr. Nusrat ...
Is MERS another SARS: The facts behind Middle East Respiratory Syndrome
2015-08-24
Atlanta, GA - August 24, 2015 - Experts show that while Middle East Respiratory Syndrome (MERS-CoV), a viral respiratory illness, is infecting less people, it has a higher mortality rate and affects a specific target population when compared to Severe Acute Respiratory Syndrome (SARS-CoV). This research is being presented at the International Conference on Emerging and Infectious Diseases in Atlanta, Georgia.
"The research conducted in this study focuses on understanding what population of individuals are most likely to become infected by MERS-CoV, compared to the population ...
Entomologists sniff out new stink bug to help soybean farmers control damage
2015-08-24
BEAUMONT -- Entomologists in Texas got a whiff of a new stink bug doing economic damage to soybeans in Texas and are developing ways to help farmers combat it, according to a report in the journal Environmental Entomology.
Various types of stink bugs have long been a problem on soybean crops, but when sweeps of fields in southeast Texas netted 65 percent redbanded stink bugs, entomologists realized this particular bug had become the predominant pest problem, according to Dr. Mo Way, an entomologist at the Texas A&M AgriLife Research and Extension Center in Beaumont.
The ...
Humans carry more antibiotic-resistant bacteria than animals they work with
2015-08-24
Philadelphia, PA, August 24, 2015 - Antibiotic-resistant bacteria are a concern for the health and well-being of both humans and farm animals. One of the most common and costly diseases faced by the dairy industry is bovine mastitis, a potentially fatal bacterial inflammation of the mammary gland (IMI). Widespread use of antibiotics to treat the disease is often blamed for generating antibiotic-resistant bacteria. However, researchers investigating staphylococcal populations responsible for causing mastitis in dairy cows in South Africa found that humans carried more antibiotic-resistant ...
Promising class of new cancer drugs might cause memory loss in mice
2015-08-24
Cancer researchers are constantly in search of more-effective and less-toxic approaches to stopping the disease, and have recently launched clinical trials testing a new class of drugs called BET inhibitors. These therapies act on a group of proteins that help regulate the expression of many genes, some of which play a role in cancer.
New findings from The Rockefeller University suggest that the original version of BET inhibitors causes molecular changes in mouse neurons, and can lead to memory loss in mice that receive it. Published in Nature Neuroscience on August ...
Compound found in red wine causes conflicting changes in dogs' immune systems
2015-08-24
Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several potentially beneficial effects on health, including cardiovascular health, stroke prevention and cancer treatments. However, scientists do not yet fully understand how the chemical works and whether or not it can be used for treatment of diseases in humans and animals.
Now, researchers at the University of Missouri have found that resveratrol does affect the immune systems of dogs in different ways when introduced to dogs' blood. Sandra Axiak-Bechtel, an assistant professor ...
Penn/Baylor Med study describes underlying cause of diabetes in dogs
2015-08-24
In a new effort, researchers from the University of Pennsylvania and Baylor College of Medicine have used advanced imaging technology to fill in details about the underlying cause of canine diabetes, which until now has been little understood. For the first time, they've precisely quantified the dramatic loss of insulin-producing beta cells in dogs with the disease and compared it to the loss observed in people with type I diabetes.
"The architecture of the canine pancreas has never been studied in the detail that we have done in this paper," said Rebecka Hess, professor ...
Study finds black bears in Yosemite forage primarily on plants and nuts
2015-08-24
Black bears in Yosemite National Park that don't seek out human foods subsist primarily on plants and nuts, according to a study conducted by biologists at UC San Diego who also found that ants and other sources of animal protein, such as mule deer, make up only a small fraction of the bears' annual diet.
Their study, published in this week's early online edition of the journal Methods in Ecology and Evolution, might surprise bear ecologists and conservationists who had long assumed that black bears in the Sierra Nevada rely on lots of protein from ants and other insects ...
Similar outcomes for mothers and babies at low risk delivered by FPs and obstetricians
2015-08-24
For pregnant women who are at low risk of complications giving birth, the risk of newborn death and maternal complications is similar for obstetric deliveries by family physicians and obstetricians, according to a large study published in CMAJ (Canadian Medical Association Journal).
"It is common to assume that more specialized or higher-volume medical care will result in improved outcomes," writes Dr. Kris Aubrey-Bassler with the Primary Healthcare Research Unit, Discipline of Family Medicine, Memorial University of Newfoundland, St. John's, Newfoundland. "The obstetric ...
Reducing pain during vaccination: New guideline to help manage pain in children and adults
2015-08-24
A new Canadian guideline aims to ensure that pain during vaccination is minimized in both children and adults. The guideline, published in CMAJ (Canadian Medical Association Journal), is targeted at all health care providers who administer vaccines.
"Pain from vaccinations is common and can make people hesitate about getting future vaccines even as adults," states Dr. Anna Taddio, Senior Associate Scientist at The Hospital for Sick Children (SickKids), Toronto, Ontario, and Leslie Dan Faculty of Pharmacy, University of Toronto. "This can put people at risk of contracting ...
Women in mostly male workplaces exhibit psychological stress response
2015-08-24
Today's workforce is highly sex-segregated -- for example, most elementary school teachers are women, while most chemistry professors are men. Indiana University Bloomington researchers Bianca Manago, a doctoral student in sociology, and Cate Taylor, an assistant professor of sociology and gender studies, examine one important consequence of this occupational sex segregation: the stress exposure of women working in highly male-dominated occupations.
"We find that such women are more likely to experience exposure to high levels of interpersonal, workplace stressors," Manago ...
Voter ID law effects hard to pinpoint
2015-08-24
Indiana's strict voter identification law may have prevented some elderly citizens from voting in the last two presidential elections, but there's little evidence it kept large numbers of voters from the polls, according to research by Indiana University Bloomington doctoral student Adam Nicholson.
Nicholson compared turnout figures in the 2000, 2004, 2008 and 2012 elections in Indiana and in Nebraska and Pennsylvania, two states without voter ID laws. Unlike most previous research on voter identification laws, the study examined data at the county level, not the state ...
Influenza vaccines provide moderate protection throughout the entire flu season
2015-08-24
Atlanta, GA - August 24, 2015 - Individuals who received the flu vaccine were protected for up to 6 months post-vaccination, the duration of most flu seasons, according to a study presented at the 2015 International Conference on Emerging Infectious Diseases.
Each flu season, researchers work to find out how effective the flu vaccine was in order to measure its value as a health intervention. Factors such as age and health of an individual, as well the level of similarity between the flu virus and the flu vaccine can play a role in how well an influenza vaccine works.
"Few ...
Climate impacts on marine biodiversity
2015-08-24
New research into the impact of climate change has found that warming oceans will cause profound changes in the global distribution of marine biodiversity.
In a study published in the journal Nature Climate Change an international research team modelled the impacts of a changing climate on the distribution of almost 13 thousand marine species, more than twelve times as many species as previously studied.
The study found that a rapidly warming climate would cause many species to expand into new regions, which would impact on native species, while others with restricted ...
New research sheds light on end of Snowball Earth period
2015-08-24
The second ice age during the Cryogenian period was not followed by the sudden and chaotic melting-back of the ice as previously thought, but ended with regular advances and retreats of the ice, according to research published by scientists from the University of Birmingham in the journal Nature Geoscience today (24 August 2015).
The researchers also found that the constant advance and retreat of ice during this period was caused by the Earth wobbling on its axis.
These ice ages are explained by a theory of Snowball Earth, which says that they represent the most ...
Mayo Clinic researchers find new code that makes reprogramming of cancer cells possible
2015-08-24
JACKSONVILLE, Fla. -- Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic's Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.
The finding, published in Nature Cell Biology, represents "an unexpected new biology that provides the code, the software for turning off cancer," says the study's senior investigator, Panos Anastasiadis, Ph.D., chair of the Department of Cancer Biology on Mayo Clinic's Florida campus.
That code was unraveled ...
Diversity in graduate medical education; women majority in 7 specialties in 2012
2015-08-24
Women accounted for the majority of graduate medical education (GME) trainees in seven specialties in 2012 but in no specialties were the percentages of black or Hispanic trainees comparable with the representation of these groups in the U.S. population, according to a research letter published online by JAMA Internal Medicine.
Diversifying the physician workforce in the United States is an ongoing goal.
Curtiland Deville, M.D., of Johns Hopkins University, Baltimore, and coauthors used publicly reported data to assess the representation of women and historically underrepresented ...
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