This is the finding of an 18-year-study of over 300,000 people with diabetes in England, from scientists from Imperial College London and published in the journal The Lancet Diabetes & Endocrinology. Thursday Feb 4th is World Cancer Day. The research, funded by the Wellcome Trust, reveals that between 2001-2018 heart disease and stroke were no longer the leading causes of death among people with diabetes, as they were 18 years ago. Diabetes affects 4.7 million people in the UK, and is caused by the body being unable to regulate blood sugar levels. Around 90 per cent have type ...

Osaka - Many different catalysts that promote the conversion of glucose to sorbitol have been studied; however, most offer certain properties while requiring compromises on others. Now, researchers from Osaka University have reported a hydrotalcite-supported nickel phosphide nanoparticle catalyst (nano-Ni2P/HT) that ticks all the boxes. Their findings are published in Green Chemistry. Sorbitol is a versatile molecule that is widely used in the food, cosmetics, and pharmaceuticals industries. There is therefore a pressing need to produce sorbitol in a sustainable, low-cost, and green manner. The nickel catalysts that are commonly used in the industrial hydrogenation of glucose to sorbitol are unstable in air and require hash reaction conditions. Rare metal alternatives--despite being ...

Remember the first rule of fight club? That's right: You don't talk about fight club. Luckily, the rules of Hollywood don't apply to science. In new published research, University of Arizona researchers report what they learned when they started their own "fight club" - an exclusive version where only insects qualify as members, with a mission to shed light on the evolution of weapons in the animal kingdom. In many animal species, fighting is a common occurrence. Individuals may fight over food, shelter or territory, but especially common are fights between males over access to females for mating. Many of the most striking and unusual features of animals are associated with these mating-related fights, including the horns of beetles and the antlers of deer. What is less clear ...

PHILADELPHA--Inflammation in the blood could serve as a new biomarker to help identify patients with advanced pancreatic cancer who won't respond to the immune-stimulating drugs known as CD40 agonists, suggests a new study from researchers in the Abramson Cancer Center of the University of Pennsylvania published in JCI Insight It is known that pancreatic cancer can cause systemic inflammation, which is readily detectable in the blood. The team found that patients with systemic inflammation had worse overall survival rates than patients without inflammation when treated with both a CD40 agonist and the chemotherapy gemcitabine. The ...

This study is the first randomised control trial to rigorously test a sequential approach to treating comorbid PTSD and major depressive disorder. Findings from a trial of 52 patients undergoing three types of treatment regime - using only Cognitive Processing Therapy (CPT), using Behavioural Activation Therapy (BA) with some CPT, or CPT with some BA - found that a combined treatment protocol resulted in meaningful reductions in PTSD and depression severity, with improvements maintained at six-month follow-up investigations. "We sought to examine whether a protocol that specifically targeted both PTSD and comorbid ...

TOKYO --Toshiba Corporation (TOKYO: 6502) and Toshiba Digital Solutions Corporation (collectively Toshiba), industry leaders in solutions for large-scale optimization problems, today announced the Ballistic Simulated Bifurcation Algorithm (bSB) and the Discrete Simulated Bifurcation Algorithm (dSB), new algorithms that far surpass the performance of Toshiba's previous Simulated Bifurcation Algorithm (SB). The new algorithms will be applied to finding solutions to highly complex problems in areas as diverse as portfolio management, drug development and logistics management. ...

Borderline Personality Disorder, or BPD, is the most common personality disorder in Australia, affecting up to 5% of the population at some stage, and Flinders University researchers warn more needs to be done to meet this high consumer needs. A new study in the Journal of Psychiatric and Mental Health Nursing (Wiley) describes how people with BPD are becoming more knowledgeable about the disorder and available treatments, but may find it difficult to find evidence-based help for their symptoms. The South Australian psychiatric researchers warn these services are constrained by stigma ...

Researchers at Flinders University are working to remedy this situation by identifying what triggers this chronic pain in the female reproductive tract. Dr Joel Castro Kraftchenko - Head of Endometriosis Research for the Visceral Pain Group (VIPER), with the College of Medicine and Public Health at Flinders University - is leading research into the pain attached to Dyspareunia, also known as vaginal hyperalgesia or painful intercourse, which is one of the most debilitating symptoms experienced by women with endometriosis and vulvodynia. Pain is detected by specialised proteins (called ion channels) that are present in sensory nerves and project from peripheral organs to the central ...

Researchers from the international BASE collaboration at CERN, Switzerland, which is led by the RIKEN Fundamental Symmetries Laboratory, have discovered a new avenue to search for axions--a hypothetical particle that is one of the candidates of dark matter particles. The group, which usually performs ultra-high precision measurements of the fundamental properties of trapped antimatter, has for the first time used the ultra-sensitive superconducting single antiproton detection system of their advanced Penning trap experiment as a sensitive dark matter antenna. If our current understanding of cosmology is correct, ordinary "visible" matter only ...

When health researchers ask pregnant women about their alcohol use, expectant women may underreport their drinking, hampering efforts to minimize alcohol use in pregnancy and prevent development of fetal alcohol spectrum disorders (FASD) in children. In a recently published study in Alcoholism: Clinical & Experimental Research, University of New Mexico scientists found that pregnant women's reporting of their own risky drinking varies greatly depending on how key questions are worded. Most women know that alcohol use during pregnancy may harm their unborn child - and that leads to fear of being ...

Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele. However, it has been known for a while that the risk due to the APOE4 allele differs considerably across populations, with Europeans having a greater risk from the APOE4 allele than Africans and African Americans. "If you inherited your APOE4 allele from your African ancestor, you have a lower risk for Alzheimer disease than if you inherited your APOE4 allele from your European ancestor," said Jeffery M. Vance, M.D., Ph.D., professor and founding chair of ...

ATLANTA - FEBRUARY 4, 2021 - Cancer ranks as a leading cause of death in every country in the world, and, for the first time, female breast cancer is the most commonly diagnosed cancer, overtaking lung cancer, according to a collaborative report, Global Cancer Statistics 2020, from the American Cancer Society (ACS) and the International Agency for Research on Cancer (IARC). Data show that 1 in 5 men and women worldwide develop cancer during their lifetime, and 1 in 8 men and 1 in 11 women die from the disease. The article describes cancer incidence and mortality at the global level and according to sex, geography, ...

Niigata, Japan - Researchers from the Graduate School of Science and Technology at Niigata University, Japan along with their collaborators from Tokyo University of Science (Japan), Yamagata University (Japan) and University of Regensburg (Germany) have published a scientific article which enhances clarity on the understanding of proton conduction mechanism in protic ionic liquids. The findings which were recently published in The Journal of Physical Chemistry B sheds light on the transport of hydrogen ions in these liquids, which opens new avenues for the development of novel energy generation and storage devices. With ...

Scientists have found genetic differences between bats killed by white-nose syndrome and bats that survived, suggesting that survivors rapidly evolve to resist the fungal disease, according to a Rutgers-led study with big implications for deciding how to safeguard bat populations. White-nose syndrome has killed millions of bats in North America since 2006, following its introduction from Europe. The syndrome, caused by the fungal pathogen Pseudogymnoascus destructans, is arguably the most catastrophic wildlife disease in history. It has led to unprecedented declines in many North American bat species, including the little brown bat (Myotis lucifugus). "Our finding that little brown bat populations have evolved, which could be why they survived, has large implications for ...

Lots of us are feeling pretty anxious about the destruction of the natural world. It turns out, humans aren't the only ones stressing out--by analyzing hormones that accumulate in fur, researchers found that rodents and marsupials living in smaller patches of South America's Atlantic Forest are under more stress than ones living in more intact forests. "We suspected that organisms in deforested areas would show higher levels of stress than animals in more pristine forests, and we found evidence that that's true," says Noé de la Sancha, a research associate at the Field Museum in Chicago, Associate Professor of Biology at Chicago State University, ...

New research published today in the journal Scientific Reports based on the largest-to-date analysis of commercial data on egg-laying hen mortality finds that mortality in higher-welfare cage-free housing systems decreases over time as management experience increases and knowledge accrues. This finding marks a major turning point in the debate over the transition in housing systems for egg-laying hens from battery cages to indoor cage-free systems, which some egg producers have argued would increase hens' mortality even as it allowed birds to stretch their wings. The study, authored by Dr. Cynthia Schuck-Paim and others, included data from 16 countries, 6,040 commercial flocks, and 176 million hens in a variety of caged and ...

DALLAS, Feb. 4, 2021 -- Stroke and heart attack survivors can reduce multiple causes of death and prevent further cardiovascular events by drinking green tea, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. The study also found daily coffee consumption helps heart attack survivors by lowering their risk of death after a heart attack and can prevent heart attacks or strokes in healthy individuals. Previous research has examined the benefits of green tea and coffee on heart health in people without a history of cardiovascular disease or cancer. Researchers in ...

BOSTON - Medical histories of patients collected and stored in electronic health records (EHR) can be rapidly leveraged to predict the probability of death from COVID-19, information that could prove valuable in managing limited therapeutic and preventive resources to combat the devastating virus, researchers from Massachusetts General Hospital (MGH) have found. In a study published in npj Digital Medicine, the team described how artificial intelligence (AI) technology enabled it to identify factors such as age, history of pneumonia, gender, race and comorbidities like diabetes and cancer as predictors of poor outcomes in COVID-19 patients. "By combining computational methods and clinical expertise, we developed a set of models to forecast ...

The open ocean is a harsh place for newborn fishes. From the minute larvae hatch from their eggs, their survival depends upon finding food and navigating ocean currents to their adult habitats--all while avoiding predators. This harrowing journey from egg to home has long been a mystery, until now. An international team including scientists from the Arizona State University Center for Global Discovery and Conservation Science (GDCS), NOAA's Pacific Islands Fisheries Science Center, and the University of Hawai'i at Mānoa have discovered a diverse array of young marine animals finding refuge within so-called 'surface slicks' in Hawai'i. Surface slicks create a superhighway of nursery habitat for more than 100 species of commercially and ecologically ...

To survive the open ocean, tiny fish larvae, freshly hatched from eggs, must find food, avoid predators, and navigate ocean currents to their adult habitats. But what the larvae of most marine species experience during these great ocean odysseys has long been a mystery, until now. A team of scientists from NOAA's Pacific Islands Fisheries Science Center, the University of Hawai'i (UH) at Mānoa, Arizona State University and elsewhere have discovered that a diverse array of marine animals find refuge in so-called 'surface slicks' in Hawai'i. These ocean features ...

The Institute for Scientific Information on Coffee (ISIC) published a new report today, titled 'Coffee and sleep in everyday lives', authored by Professor Renata Riha, from the Department of Sleep Medicine at the University of Edinburgh. It reviews the latest research into coffee's effect on sleep and suggests that while drinking coffee early in the day can help support alertness and concentration levels1, especially when sleep patterns are disturbed; decreasing intake six hours before bedtime may help reduce its impact on sleep2. Coffee is largely consumed daily for the pleasure of its taste3, as well as its beneficial effect on wakefulness and concentration (due to its caffeine content)4. ...

A new study further highlighting a potential physiological cause of clinical depression could guide future treatment options for this serious mental health disorder. Published in Frontiers in Psychiatry, researchers show differences between the cellular composition of the brain in depressed adults who died by suicide and non-psychiatric individuals who died suddenly by other means. "We found a reduced number of astrocytes, highlighted by staining the protein vimentin, in many regions of the brain in depressed adults," reports Naguib Mechawar, a Professor at the Department of Psychiatry, McGill University, Canada, and senior author of this article. ...

Researchers from University of Notre Dame, York University (Canada), and University of New England (Australia) published a new paper in the Journal of Marketing that identifies a novel reason why people under-save and demonstrates a simple, short, and inexpensive intervention that increases intentions to save and actual savings. The study, forthcoming in the Journal of Marketing, is titled "Popping the Positive Illusion of Financial Responsibility Can Increase Personal Savings: Applications in Emerging and Western Markets" and is authored by Emily Garbinsky, Nicole Mead, and Daniel Gregg. People around the world are not saving enough money. Since increasing ...

WASHINGTON--The start of California's annual rainy season has been pushed back from November to December, prolonging the state's increasingly destructive wildfire season by nearly a month, according to new research. The study cannot confirm the shift is connected to climate change, but the results are consistent with climate models that predict drier autumns for California in a warming climate, according to the authors. Wildfires can occur at any time in California, but fires typically burn from May through October, when the state is in its dry season. The start of the rainy season, historically in November, ends wildfire season as plants become too moist to burn. California's rainy season has been starting progressively later in recent decades and climate ...

Researchers from Nanyang Technological University, Singapore (NTU Singapore), Singapore University of Technology and Design (SUTD) and Khoo Teck Puat Hospital (KTPH) have developed a new way to create "food inks" from fresh and frozen vegetables, that preserves their nutrition and flavour better than existing methods. Food inks are usually made from pureed foods in liquid or semi-solid form, then 3D-printed by extrusion from a nozzle, and assembled layer by layer. Pureed foods are usually served to patients suffering from swallowing difficulties known as dysphagia. To present the ...