A team of researchers at Case Western Reserve University School of Medicine, led by Dr. Mark W. Jackson, have developed a novel method to identify genes that, when overexpressed, make normal cells behave like cancer cells. Using this method, the Jackson laboratory has identified a new oncogene, which is a gene that contributes to the development of cancer, named FAM83B. "We made our discovery in a model of breast cancer," said Mark W. Jackson, Ph.D., Assistant Professor, Department of Pathology, Case Western Reserve University School of Medicine, Case Comprehensive Cancer ...

Poor oral health, dental disease, and tooth pain can put kids at a serious disadvantage in school, according to a new Ostrow School of Dentistry of USC study. "The Impact of Oral Health on the Academic Performance of Disadvantaged Children," appearing in the September 2012 issue of the American Journal of Public Health, examined nearly 1500 socioeconomically disadvantaged elementary and high school children in the Los Angeles Unified School District, matching their oral health status to their academic achievement and attendance records. Ostrow researchers had previously ...

VIDEO: MU researchers studied how college-age women view their bodies and how they feel about media messages aimed at women. Based on focus group research findings, the MU team developed an... Click here for more information. COLUMBIA, Mo. –When it comes to college-age individuals taking care of their bodies, appearance is more important than health, research conducted at the University of Missouri suggests. María Len-Ríos, an associate professor of strategic communication, ...

Ten more DNA regions linked to type 2 diabetes have been discovered by an international team of researchers, bringing the total to over 60. The study provides a fuller picture of the genetics and biological processes underlying type 2 diabetes, with some clear patterns emerging. The international team, led by researchers from the University of Oxford, the Broad Institute of Harvard and MIT, and the University of Michigan, Ann Arbor, used a new DNA chip to probe deeper into the genetic variations that commonly occur in our DNA and which may have some connection to type ...

Major depression or chronic stress can cause the loss of brain volume, a condition that contributes to both emotional and cognitive impairment. Now a team of researchers led by Yale scientists has discovered one reason why this occurs — a single genetic switch that triggers loss of brain connections in humans and depression in animal models. The findings, reported in the Aug. 12 issue of the journal Nature Medicine, show that the genetic switch known as a transcription factor represses the expression of several genes that are necessary for the formation of synaptic connections ...

Researchers have identified 38 new genetic regions that are associated with glucose and insulin levels in the blood. This brings the total number of genetic regions associated with glucose and insulin levels to 53, over half of which are associated with type 2 diabetes. The researchers used a technology that is 100 times more powerful than previous techniques used to follow-up on genome-wide association results. This technology, Metabochip, was designed as a cost-effective way to find and map genomic regions for a range of cardiovascular and metabolic characteristics ...

With a thin sliver of diamond, scientists at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have transformed the Linac Coherent Light Source (LCLS) into an even more precise tool for exploring the nanoworld. The improvements yield laser pulses focused to higher intensity in a much narrower band of X-ray wavelengths, and may enable experiments that have never before been possible. In a process called "self-seeding," the diamond filters the laser beam to a single X-ray color, which is then amplified. Like trading a hatchet for a scalpel, the ...

Genetics researchers have identified a key gene that, when mutated, causes the rare multisystem disorder Cornelia deLange syndrome (CdLS). By revealing how mutations in the HDAC8 gene disrupt the biology of proteins that control both gene expression and cell division, the research sheds light on this disease, which causes intellectual disability, limb deformations and other disabilities resulting from impairments in early development. "As we better understand how CdLS operates at the level of cell biology, we will be better able to define strategies for devising treatments ...

TEMPE, Ariz. – According to the United Nations' 2011 Revision of World Urbanization Prospects, global urban population is expected to gain more than 2.5 billion new inhabitants through 2050. Such sharp increases in the number of urban dwellers will require considerable conversion of natural to urban landscapes, resulting in newly developing and expanding megapolitan areas. Could climate impacts arising from built environment growth pose additional concerns for urban residents also expected to deal with impacts resulting from global climate change? In the first study to ...

A team of researchers at Columbia Engineering, led by Applied Physics and Applied Mathematics Associate Professor Latha Venkataraman and in collaboration with Mark Hybertsen from the Center for Functional Nanomaterials at the U.S. Department of Energy's Brookhaven National Laboratory, has succeeded in performing the first quantitative characterization of van der Waals interactions at metal/organic interfaces at the single-molecule level. In a study published online August 12 in the Advance Online Publication on Nature Materials's website , the team has shown the existence ...

This press release is available in German. Many crop plants worldwide are attacked by a group of fungi that numbers more than 680 different species. After initial invasion, they first grow stealthily inside living plant cells, but then switch to a highly destructive life-style, feeding on dead cells. While some species switch completely to host destruction, others maintain stealthy and destructive modes simultaneously. A team of scientists led by Richard O'Connell from the Max Planck Institute for Plant Breeding Research in Cologne and Lisa Vaillancourt from University ...

CHICAGO --- Has a summer cold or mold allergy stuffed up your nose and dampened your sense of smell? We take it for granted that once our nostrils clear, our sniffers will dependably rebound and alert us to a lurking neighborhood skunk or a caramel corn shop ahead. That dependability is no accident. It turns out the brain is working overtime behind the scenes to make sure the sense of smell is just as sharp after the nose recovers. A new Northwestern Medicine study shows that after the human nose is experimentally blocked for one week, brain activity rapidly ...

Fracture under combined mechanical and electric loading is currently a hot research area in the global fracture community, while electric sticking is a major concern in the design and fabrication of micro/nanoelectromechanical systems. Professor ZHANG Tong-Yi and his student, Mr. Tao Xie, from the Department of Mechanical Engineering, Hong Kong University of Science and Technology, found that the two problems are switchable, depending on the loading conditions, sample geometries and material properties. Based on his 20-year research experience on the fracture of dielectric ...

OAK BROOK, Ill. – Researchers at the Mayo Clinic say a common condition called leukoaraiosis, made up of tiny areas in the brain that have been deprived of oxygen and appear as bright white dots on MRI scans, is not a harmless part of the aging process, but rather a disease that alters brain function in the elderly. Results of their study are published online in the journal Radiology. "There has been a lot of controversy over these commonly identified abnormalities on MRI scans and their clinical impact," said Kirk M. Welker, M.D., assistant professor of radiology in ...

Contrary to clinical recommendations, older women with early stage breast cancer may want to undergo radiation after lumpectomy to help ensure that they will not need a mastectomy in the future. That is the conclusion of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The findings indicate that current thinking on the risks and benefits of radiation for early stage breast cancer in older women may be inaccurate. National treatment guidelines state that older women with early stage breast cancer that has not spread ...

Persistent and loud snoring in young children is associated with problem behaviors, according to a new study published online in Pediatrics. These behaviors include hyperactivity, depression and inattention, according to Dean Beebe, PhD, director of the neuropsychology program at Cincinnati Children's Hospital Medical Center and lead author of the study. "The strongest predictors of persistent snoring were lower socioeconomic status and the absence or shorter duration of breastfeeding," says Dr. Beebe. "This would suggest that doctors routinely screen for and track ...

HOUSTON — For the majority of older, early-stage breast cancer patients, radiation therapy following breast conserving surgery may help prevent the need for a later mastectomy, according to research from The University of Texas MD Anderson Cancer Center. The findings, published in the journal Cancer, are contrary to current national treatment guidelines, which recommend that older women with early stage, estrogen-positive disease be treated with lumpectomy followed by estrogen blocker therapy alone -- and forgo radiation therapy post-surgery. The potential benefit of ...

Walker Author Tours continues to bring authors to the attention of readers everywhere via virtual book tours. Now they present a three-week-long online book blog tour for Michelle Devon's suspenseful novella, Celeste. This book tour includes stops at various book blogs all over the internet where readers will find reviews, author interviews, and blog posts by the author. Virtual book tours are a convenient and entertaining way to discover the latest books and learn about authors. The Celeste book tour will run from August 13-17, August 20-24, and September 10-14, 2012. ...

Sara Evans is back to her music career with the new album, Stronger and newest single, "Anywhere". She talks about her new life and her partnership with Room to Run with CelebrityCafe. Sara will be on a tour to push her new album this summer. She also expresses her big hope for her new song, "Anything". "It was a great experience writing this song. I didn't write the song, my brother Matt Evans did. It's the first single he's ever had on one of my albums. I'm really rooting for the song, and I'm hoping it will be a big hit." Sara said. She ...

NAAFA has just concluded another successful annual fund raising convention held at the Westin SF Airport Hotel in Millbrae, CA. During the Annual General Meeting on Friday evening, NAAFA Chairperson Jason Docherty reviewed NAAFA's accomplishments over the past five years. This year concluded the initial five year plan set forth by your current Board of Directors. Fantastic changes have taken place in our organization during this period of time and we are now positioned to launch even bigger projects, and exciting updates to existing projects, as we continue to move forward ...

Just in time for the fall retail season, Paypal has now been made an available payment method on the Aggro online store. Paypal is a convenient online money transfer service that has become universal for online shopping. The service allows people to send money safely and confidentially, with the flexibility to pay using their account balances, bank accounts, credit cards or promotional financing. Paypal currently serves 113.2 million active accounts in 190 markets and 25 currencies around the world. You can be confident that all of your online transactions are secure and ...

Radisson Hotel Kandla, the first 5-star hotel in the Kutch District, a part of Gujarat state and India's largest district, recently opened its doors for business and leisure travellers. Located at Rajvee Complex, Airport Road, Galpadar, Gandhidham, Kutch Gujarat India, the 117-room hotel is just minutes away from the Kandla airport the Gandhidham railway station. It is also close to Kandla port, a major maritime hub in Gandhidham city and an important trade center for India, particularly with the salt industry in Gandhidham accounting for 40 percent of the country's salt ...

- Cosmetology students at Hair Benders Academy, 851 E. State Road in Longwood are helping students ages 4-18 return to school in style with a variety of back to school specials. The specials include: buy one get one free haircuts; $2 off any regularly priced haircut; $4 off acrylic nail services and 15% off all Peter Hantz retail products. "By offering deep discounts to our already reasonably-priced services, we can help ensure more students can go back to school in style," said Jessica Wolman, one of the owners of the Florida cosmetology school. The ...

The Massachusetts Broadcasters Hall of Fame will present its annual Gala Awards Ceremony and Luncheon on Thursday, September 13 from 12:00 PM to 2:00 PM at the Boston Marriott Quincy Hotel. Hosted by WBZ Radio 1030's Jordan Rich, the Hall of Fame will induct fourteen of Massachusetts' most popular and respected radio and television broadcasters into the Hall of Fame. This year's event, will be an exciting one for sure as the Emmy-Award winning Haverhill, Massachusetts native Tom Bergeron makes an appearance at LONG last, five years after he was honored in 2007. Tickets ...

The workout will benefit Awaken Women of Excellence, an organization that supports women in the Columbus area as they strive to lead progressive lives. Past YUN FIT charity workouts have raised over $3400 for various causes and organizations in Central Ohio. The event will take place on Saturday, August 25, from 9:30 - 10:15 a.m., at Dexter Falls Park, 5091 Dexter Falls Road, Columbus. Participants donate a minimum of $15 to join the class, and 100 percent of the proceeds go to Awaken Women of Excellence. Participants can expect a great workout for a great cause. ...