Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells. "We have identified a new direction for cancer therapy and the new direction is leading us to a reduction in toxicity in cancer therapy, compared with chemotherapy or radiation therapy," ...

BOSTON (August 1, 2012) -- A comprehensive study using electronic dental records to profile the oral health status of adults with intellectual and developmental disabilities (I/DD) has concluded that access to specialized dental care alone is not sufficient to meet the community's substantial oral health needs. The findings, published as the cover article in the August issue of The Journal of the American Dental Association, provide a foundation for further investigation into the significant oral health needs of adults with I/DD and the development of preventive oral ...

MTR Global Venture Capital Group announced today that it has appointed Excel Trading Co., Limited's CEO Mr. Chuck M. Richardson to its Board of Directors team. Under Chuck's leadership, Excel Trading has sustained tremendous growth while considerably expanding its geographic reach. Since Chuck took the CEO position in 2008, Excel Trading has grown almost 450% from $85.5 Million to $348.75 Million, which is a great direction experience that Chuck is bringing to MTR Global as a part of his role in here. "We asked Mr. Richardson to join our Board of Directors because ...

Today EcoPlum, the green shopping rewards site, expands its online boutique with a unique collection of eco friendly products for the home by BottleHood. The new Home & Housewares section at EcoPlum launches with BottleHood's handcrafted glassware and wooden serving boards. These true American originals are made from reclaimed branded bottles and oak wine barrels. In August, customers purchasing BottleHood housewares at EcoPlum earn two EcoChipz rewards points for every dollar spent. BottleHood repurposes its glassware from wine, beer, liquor, soda and water bottles, ...

Inverkeithing, United Kingdom - (July 30, 2012) - Steel Buildings Design is part of the largest cold rolled steel building group in the United Kingdom. It is also the first ISO Quality Assured Steel Buildings supplier in the country. For more than 20 years, the company has been designing and building bespoke steel buildings for numerous clients. Today, Steel Buildings Design has expanded their products and services to include different types of buildings in their construction line up. Their building designs are suitable and can be adapted to almost any type of application. ...

As organizations struggle to perform against expectations and command attention in the age of immediacy, top thought leaders at Thruue Inc. are helping executives reinvent their corporate purpose/vision, and make transformational decisions for future relevancy and growth. Thruue Inc. is dedicated to the belief that only by enabling reflective thinking can big ideas emerge to drive action and evolve culture within high performing organizations. Internationally recognized author and strategist Daniel Forrester and seasoned consulting and service industry veteran Matt Lane ...

The dog dayz of this sizzling summer will be much cooler when high profile celebrities and their prized pooches receive HollyWOOF, Distinctive Assets' annual gift bag of the newest innovative dog products. Making sure Hollywood Hounds are found, Tagg - The Pet Tracker is an advanced pet tracking system equipped with GPS and wireless capabilities, enables owners to track where their pups are and be notified by text and email if they wander off beyond designated zones. For those D-List smells, itches and skin issues comes Farm Dog Naturals' new line of products, Relief ...

CDM Media extended an invitation to CIOs and IT executives today to speak at the upcoming CIO Manufacturing Summit, to be held Aug. 26-28, 2012, in Scottsdale, Ariz. The CIO Manufacturing Summit is the premier event for technology leaders and innovative thinkers, specifically CIOs, in the manufacturing industry. The summit's strategic agenda is designed to maximize efficiency and offer unique insight into present and future challenges facing CIOs in the industry. A few of this year's agenda session titles: - Securing the Smart Device-Do You Have a BYOC (Bring ...

Accurate Always, Inc today announced the launch of an educational website at http://www.voip-call-recording.com, which aims to simplify enterprise VoIP call recording by helping readers intelligently design and implement a comprehensive IP voice recording system from the start. As there are many proprietary IP-enabled PBX, gateways, media servers, SIP trunks and other ways to interface while recording IP voice, Accurate Always provides a map, with clear access to information and additional resources, which are helpful when determining how to best record VoIP calls with ...

The Lakeland Animal Shelter will host the 9th Annual Turtle Open to benefit the shelter on August 2, 2012, from 11 a.m. to 8 p.m. at Hawk's View Golf Club in Lake Geneva, Wis. Teams of four will have the opportunity to experience a great game of 18-hole scramble on Como Crossings at Hawk's View. Each team will enjoy golf, and carting around on Lake Geneva's only 5-star championship course. It is a par 72 course with 7,074 yards of challenging golf among beautiful woodlands. There will be a shotgun start at noon with a lunch buffet. Participants can also enjoy hole prize ...

San Francisco Giants outfielder Melky Cabrera has had the hot hand wearing Franklin batting gloves this season. The former Yankee and this year's All-Star MVP leads the Major Leagues with 139 hits, and would become the first Giants player to top the big leagues in hits since the immortal Willie Mays in 1960. Cabrera is hitting a blistering .353 as of Sunday's games with 10 home runs and 51 RBI. He is batting .361 in July. His average is second in the majors behind Andrew McCutchen of the Pirates at .368 Cabrera wears the Franklin model NEO CLASSIC gloves. Another ...

People often choose to file bankruptcy because they encounter a crisis in their lives, such as an unexpected job loss or medical bills, that destabilizes them financially. They seek bankruptcy protection in order to get a fresh start and regain their financial footing. Sometimes people need to consider bankruptcy more than one time in their lives and people should be aware of the restrictions the law places on filing for bankruptcymultiple times. Chapter 7 Bankruptcy Filing Limits Those who successfully filed Chapter 7 bankruptcy and received a debt discharge need ...

North Carolina residents who experience frequent pain in certain areas of the body may suffer from repetitive stress injury. The condition is referred to by a number of different names including repetitive strain injury, occupational overuse syndrome and cumulative trauma disorder. Individuals who suffer from severe RSI injuries may qualify for workers' compensation. RSI injuries are painful or uncomfortable feelings in the muscles, tendons, nerves or other soft tissues. They normally occur due to repetitive use of specific areas of the body. Arms, elbows and wrists ...

As people become more dependent on computers, they are storing more information digitally. What people might not realize is that they are creating digital assets that should be included in their estate plans. When people think of estate plans, they may only consider things like houses, money and other tangible personal property. However, some of the things people have online are just as important to them as assets traditionally included in estate plans, and people should take steps to ensure that they spell out their wishes for their digital assets in their estate plans. Making ...

Estate planning professionals have long used intentionally defective grantor trustsas a means of reducing estate taxes and preserving assets. However, President Obama's proposed 2013 budget would eliminate the savings that IDGTs offer. People should be aware of the potential changes to tax laws and how they could affect IDGTs. What Is an IDGT? An IDGT is a trust that takes advantage of the split between the income tax laws and the tax rules governing gifts or money transfers. These trusts are a means of freezing the appreciation of assets for the purposes of calculating ...

Like other places in Georgia car accidents caused by cellphone use behind the wheel is an issue in Macon and Bibb County. Distracted driving kills more than 5,000 people per year across the United States according to a new study by The CQ Reporter. In 2009 alone over 5,400 people were killed and 448,000 people were injured by distracted drivers. Teen drivers have an even higher risk of accident when they practice distracted driving activities. In fact, 16 percent of distracted driving deaths involve teen drivers, and a significant number of those deaths are caused by cell ...

The number of people receiving Social Security disability benefits is on the rise. It has almost tripled since 1980, when there were about 2.8 million workers and 1.8 million dependents receiving Social Security disability insurance payments. By 2010, this number rose to 8.2 million workers and 2.1 million dependents, reports Reuters news. Social Security disability benefits may be awarded to people who are unable to work because of a disability. However, they are not awarded to people simply because they are unable to find work. Relationship Between SSDI and Unemployment In ...

Authorities across the U.S. are cracking down on drinking and driving. Kansas is no exception to the trend. State lawmakers passed a new law targeting those with multiple driving under the influence convictions who refuse to take chemical tests. Kansas drivers should know about the changes to the law and the potential penalties they face for violating it. Changes to DUI Law Kansas will now be one of a few states where it is a criminal offense for a driver who has a prior DUI conviction to refuse a chemical test when pulled over on suspicion of drunk driving. A common ...

On June 14, 2012, the California Senate approved AB 2127, a bill that would change the state's work release program. Under the changes the bill proposes, people convicted of low-level misdemeanors such as DUI offenseswould have a greater opportunity to prepare for life after incarceration with new programs to be offered that would count as alternatives to actual custody, or in addition thereto. The Assembly already passed a version of the bill, and now the bill returns to the Assembly for approval of the Senate amendments. Current Work Release Law California law already ...

In June 2012, a California Highway Patrol officer appeared for her preliminary hearing on felony DUI charges, one of the many court appearances she will face in relation to the charges. The 17-year CHP veteran was arrested after being involved in an auto accident where others suffered injuries. If convicted, the woman faces severe penalties. Four-Car Wreck The officer's DUI charges stem from an accident on January 14, 2012. The officer was off duty, driving on South Bonnyview Avenue in Redding, California, and police allege that she caused a four-car wreck because ...

Burbank based AlphaDogs Post Production is excited to announce that the feature film Portion has been awarded the Grand Prize at the 18th Annual San Antonio Film Festival. The film stars Bruno Bichir who also won the Santikos award at the festival for his outstanding performance as leading actor. Portion tells the story of Mexican illegal immigrant Luis (Bruno Bichir) who is faced with a tough choice when his mother—who lives in Mexico—falls gravely ill right before his final immigration interview. Luis is torn between risking a border crossing to care for his ailing mother, ...

BlueGrace Logistics, the nation's most progressive logistics, transportation and technology provider, has recently announced a newly designed website at http://www.myBlueGrace.com. The new site is launching Saturday, August 4, 2012, and is now streamlined with a direct approach, allowing customers access to new and improved features. The new website offers quick and easy access to the cutting edge technology of the company's transportation management system, BlueShip . Recently listed in Inbound Logistics' TMS Buyer's Guide 2012, this easy-to-use platform offers clients ...

Bell Nunnally & Martin LLP (www.bellnunnally.com) attorney Nicole M. Eason has been selected by the Dallas Association of Young Lawyers (DAYL) to participate in its 2012 Leadership Program. DAYL Leadership Program members are selected from a pool of young attorney applicants throughout the Dallas area who have expressed an interest in making a difference in the community and a desire to become more active with the bar. Each year, approximately 40 attorneys are accepted. Members of the Leadership Program participate in a series of informational meetings where they ...

General contractors call the shots in most construction projects, taking the lead in all important operations including coordinating subcontractors, supervising job sites, and many other responsibilities to ensure projects stay on time and within budget. The many risks involved with leading these projects makes California contractors insurance essential to protect the business against losses that may result from a lawsuit. One of the common misconceptions of contractors insurance is that it only applies to general contractors. But subcontractors such as carpenters, roofers, ...

"Over the last couple years, words like ascension are being causally tossed around, without an understanding of the underlying meaning," states McCall. Her free seminar aims to sweep away the confusion and highlight the connection between the planetary and personal ascension process. "I'm hearing a lot of the same questions from clients: 'Why is my energy low? Why do I feel different? Why is so much of my old life (friends, relationships, emotional issues) changing so rapidly?' For many, the answers can be found within the 2012 ascension process," ...