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SC Hospitality Association - Greater Greenville Chapter Appoints Holiday Inn Express Simpsonville Hotel's General Manager to their Board of Directors

SC Hospitality Association - Greater Greenville Chapter Appoints Holiday Inn Express Simpsonville Hotels General Manager to their Board of Directors
2012-08-14
Greg Carpenter, General Manager of the Holiday Inn Express Simpsonville Hotel was recently appointed to The Board of Director's for the South Carolina Hospitality Association (SCHA) - Greater Greenville Chapter. A non-partisan trade organization, SCHA serves the state's lodging and restaurant industry. SCHA strives to represent the best interests of its members on small business issues, hospitality and tourism concerns and towards the protection of South Carolina's quality of life. The Board of Directors for SCHA - Greater Greenville Chapter is responsible for successfully ...

Jose Canseco to Host Video Blog on Steroid.com

2012-08-14
Baseball great, Jose Canseco, signs with Steroid.com as the host of a new video blog, "Canseco on Steroids". The videos will be posted twice a week and hosted by the world's largest source of anabolic steroid information. Steroid.com provides the controversial author of the best selling book, "Juiced: Wild Times, Rampant 'Roids, Smash Hits and How Baseball Got Big," free range to discuss topics in true contentious Conseco spirit. Steroid.com is proud to feature "Canseco on Steroids" alongside its extensive online community, detailed steroid ...

Michaels Announces Vendor and Transportation Partner of the Year Awards

2012-08-14
Michaels Stores, Inc. announced the Vendor and Transportation Partner of the Year Awards at the Company's 15th annual Vendor Conference. The Company hosted the event on Monday, August 13, 2012, at the Hilton Anatole Hotel in Dallas. Twelve vendor partners were recognized for their contributions to Michaels' success over the past year. Every year, Michaels selects one vendor who stands above the rest by providing product innovation, customer education and inspiration, quality products and efficiency in supply chain. This year, both Michaels and Aaron Brothers, a wholly ...

Former US Senate Staffers Pen Wickedly Funny Novel about Life on the Hill: Capitol Hell Will Get Your Vote This Election Season

2012-08-14
Jayne Jones and Alicia Long cut their political teeth as idealistic young staffers on Capitol Hill working for US Senator Norm Coleman. That eye-opening behind-the-scenes experience has lead them to write Capitol Hell, a saucy novel about the crazy co-workers, high maintenance politicians, and over-the-top entourages that can only be found inside the beltway. "Our time on the Hill coupled with countless other hilarious stories from congressional offices and staffers gave us an endless supply of crazy to write about," said Jayne. "We know people are going ...

For young birds, getting stressed out can be a good thing

2012-08-13
CORVALLIS, Ore. – Many studies have found that high levels of hormones that are associated with stress are a sign of poor fitness and reduced chance of survival – but recent research on young songbirds found that some elevated hormones can be a good thing, often the difference between life and death. The new research concluded that elevated levels of glucocorticoid hormones, which are part of the natural response to stress, were related to the movement, feeding, and anti-predator behaviors of juvenile birds. The findings were made by researchers at Oregon State University ...

Enzymes implicated in disease processes attack one another instead of harming body proteins

Enzymes implicated in disease processes attack one another instead of harming body proteins
2012-08-13
Researchers for the first time have shown that members of a family of enzymes known as cathepsins – which are implicated in many disease processes – may attack one another instead of the bodily proteins they normally degrade. Dubbed "cathepsin cannibalism," the phenomenon may help explain problems with drugs that have been developed to inhibit the effects of these powerful proteases. Cathepsins are involved in disease processes as varied as cancer metastasis, atherosclerosis, cardiovascular disease, osteoporosis and arthritis. Because cathepsins have harmful effects ...

New class of proteins allows breast cancer cells to evade tyrosine kinase inhibitors

2012-08-13
Aberrant regulation of cell growth pathways is required for normal cells to become cancerous, and in many types of cancer, cell growth is driven by a group of enzymes known as receptor tyrosine kinases (RTKs). The RTK epidermal growth factor receptor (EGFR) is overexpressed in over 30% of breast cancers; however, drugs that target RTKs, known as tyrosine kinase inhibitors (TKIs) have not been effective in treating breast cancer. Researchers believe that the cancer cells escape TKIs by circumventing the RTKs and utilizing other enzymes that are not TKI-sensitive. In the ...

Common antibiotics pose a rare risk of severe liver injury in older patients

2012-08-13
Please credit CMAJ, not the Canadian Medical Association. CMAJ is an independent medical journal; views expressed here do not necessarily reflect those of its owner, the CMA. END ...

Protein that helps tumor blood vessels mature could make cancer drugs more effective

Protein that helps tumor blood vessels mature could make cancer drugs more effective
2012-08-13
ORLANDO, Fla., August 13, 2012 – To survive, tumors need blood supply to provide them with nutrients and oxygen. To get that supply, cancer cells stimulate new blood vessel growth—a process called tumor angiogenesis. Many attempts have been made to inhibit this process as a means to choke off tumors. But tumor angiogenesis can be sloppy, resulting in immature and malformed blood vessels. Since anti-cancer drugs are carried to tumors by the bloodstream, abnormal blood vessel development also hampers delivery. What if, rather than putting a stop to angiogenesis, we could ...

Journal of Clinical Investigation early table of contents for Aug. 13, 2012

2012-08-13
New class of proteins allows breast cancer cells to evade Tyrosine Kinase Inhibitors Aberrant regulation of cell growth pathways is required for normal cells to become cancerous, and in many types of cancer, cell growth is driven by a group of enzymes known as receptor tyrosine kinases (RTKs). The RTK epidermal growth factor receptor (EGFR) is overexpressed in over 30% of breast cancers; however, drugs that target RTKs, known as tyrosine kinase inhibitors (TKIs) have not been effective in treating breast cancer. Researchers believe that the cancer cells escape TKIs by ...

CNIO researchers discover a new therapy that prevents lung cancer growth in mice

2012-08-13
Lung cancer is one of the most aggressive types of cancer and the most common cause of death from this disease worldwide. Despite the progress in the molecular biology of lung cancer achieved in recent years, the mechanisms used by tumor cells to grow and spread throughout the body are not yet completely understood. This lack of information is responsible for the limited range of available therapeutic possibilities and their undesirable side effects. The Tumour Suppression Group of the Spanish National Cancer Research Centre (CNIO), led by Manuel Serrano, has deciphered ...

Fruity science halves fat in chocolate

2012-08-13
Scientists have found a way to replace up to 50 per cent of chocolate's fat content with fruit juice. University of Warwick chemists have taken out much of the cocoa butter and milk fats that go into chocolate bars, substituting them with tiny droplets of juice measuring under 30 microns in diameter. They infused orange and cranberry juice into milk, dark and white chocolate using what is known as a Pickering emulsion. Crucially, the clever chemistry does not take away the chocolatey 'mouth-feel' given by the fatty ingredients. This is because the new technique maintains ...

New bacteria-resistant materials discovered

New bacteria-resistant materials discovered
2012-08-13
Using state-of-the-art technology scientists at The University of Nottingham have discovered a new class of polymers that are resistant to bacterial attachment. These new materials could lead to a significant reduction in hospital infections and medical device failures. Medical device associated infections can lead to systemic infections or device failure, costing the NHS £1bn a year. Affecting many commonly used devices including urinary and venous catheters — bacteria form communities known as biofilms. This 'strength in numbers approach' protects them against the bodies' ...

The ins and outs of building the sperm tail

The ins and outs of building the sperm tail
2012-08-13
Sperm swim, lung cells sweep mucus away, and the cells in the female Fallopian tube move eggs from the ovary to the uterus. Underlying these phenomena are flagella – slender, hair-like structures extending from the surface of the cells, that bend, beat or wave rhythmically. In the latest issue of the journal Developmental Cell*, scientists from the Instituto Gulbenkian de Ciência (IGC), in Portugal, have dissected how sperm cells of the fruit fly build their flagella. These findings pave the way to further understand the molecules and processes that may trigger a variety ...

NTU scientist invents pocket living room TV

2012-08-13
Leaving your TV show midway because you had to leave your home will no longer happen as you can now 'pull' the programme on your TV screen onto your tablet and continue watching it seamlessly. You can also watch the same TV show or movie together with your family and friends, no matter which part of the world they are in. Not only that but you'll be able to discuss the show, whether you are on your personal tablet or smart phone, through a channel of your choice, be it video chat, voice or text. The world's first 'pick up and throw back' video feature allows your video ...

Smoking increases, while alcohol consumption may decrease risk of ALS

2012-08-13
A population-based case-control study of the rare but devastating neurological disease amyotrophic lateral sclerosis (ALS) has shown that the risk of such disease is increased among smokers, as has been shown previously. However, surprisingly, the risk of ALS was found to be markedly lower among consumers of alcohol than among abstainers. Forum reviewers thought that this was a well-done and important paper, as it is a population-based analysis, with almost 500 cases of ALS, a very large number of cases for this rare disease. They were especially struck by the magnitude ...

Clemson researchers make optical fibers from common materials

Clemson researchers make optical fibers from common materials
2012-08-13
CLEMSON — Clemson researchers are taking common materials to uncommon places by transforming easily obtainable and affordable materials into fiber. Their findings are published in Nature Photonics, the world's top journal focused on light-based technologies. "We have used a highly purified version of beach sand (silica) for fiber for the last 40 years," said John Ballato, director of the Center for Optical Materials Science and Engineering Technologies at Clemson University. "As a matter of fact, the 2009 Nobel Prize in Physics was awarded for the development of silica ...

BUSM researchers part of multi-center study on cardiac amyloidosis

2012-08-13
(Boston) - Researchers at Boston University School of Medicine (BUSM) have been part of a multicenter observational study called TRACS (Transthyretin Amyloidosis Cardiac Study) to help determine the health significance of a particular gene mutation which is commonly found in Black Americans. The gene, transthyretin (TTR) and the mutation V122I, is seen in about four percent of African Americans or roughly 1.5 million people. The mutation is strongly associated with a condition called cardiac amyloidosis - a disorder where the abnormally mutated TTR protein deposits in ...

The NBA league is more equal than the ACB

The NBA league is more equal than the ACB
2012-08-13
Competitiveness amongst NBA teams is more constant throughout seasons than during the ACB basketball league (Spain), which also falls after every Olympic Games. According to a study from the University of Las Palmas de Gran Canaria, the differences could be attributed to economic and organisational reasons: in the NBA there is just one division, there is a salary cap and the weakest teams have access to good players. The National Basketball Association (NBA) of North America and the Association of Basketball Clubs (ACB) of Spain are the best and most competitive basketball ...

Ancient seal may add substance to the legend of Samson

Ancient seal may add substance to the legend of Samson
2012-08-13
Tel Aviv University researchers recently uncovered a seal, measuring 15 millimetres (about a half-inch) in diameter, which depicts a human figure next to a lion at the archaeological site of Beth Shemesh, located between the Biblical cities of Zorah and Eshtaol, where Samson was born, flourished, and finally buried, according to the book of Judges. The scene engraved on the seal, the time period, and the location of the discovery all point to a probable reference to the story of Samson, the legendary heroic figure whose adventures famously included a victory in hand-to-paw ...

AERA et al. bring science to bear in major affirmative action case

2012-08-13
WASHINGTON, August 13, 2012─On August 13, AERA filed an amicus curiae brief in the U.S. Supreme Court case of Fisher v. University of Texas at Austin. The association is joined by seven other scientific societies in urging the Court to consider an overwhelming body of scientific evidence relevant to the case. "AERA has a fundamental interest in the accurate presentation of social science research on these important questions of law. Quite simply, we have a responsibility to enable the Court to make its determinations based on the best scientific evidence available," ...

Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research

Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research
2012-08-13
New Rochelle, NY, August 13, 2012—Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research. Prolonged embryonic cryopreservation as an alternative source of ES cells is the focus of an article in BioResearch Open Access, a new bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc. The article is available free online at the BioResearch Open Access website. Kamthorn Pruksananonda ...

Rejected drug may protect against toxic substance common to Alzheimer's and Parkinson's diseases

2012-08-13
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions. An international team led by Mount Sinai School of Medicine scientists found that latrepiridine, known commercially as Dimebon, reduced the level of at least two neurodegeneration-related proteins in mice. Latrepirdine was initially sold as an antihistamine in Russia, following its approval for use there in 1983. In the 1990s, ...

Diabetes drugs taken by over 15 million Americans raises risk of bladder cancer

2012-08-13
PHILADELPHIA -- A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that patients taking thiazolidinedione (TZDs) drugs – which account for up to 20 percent of the drugs prescribed to diabetics in the United States -- are two to three times more likely to develop bladder cancer than those who took a sulfonylurea drug, another common class of medications for ...

Mount Sinai researchers identify new drug target for schizophrenia

2012-08-13
Researchers at Mount Sinai School of Medicine may have discovered why certain drugs to treat schizophrenia are ineffective in some patients. Published online in Nature Neuroscience, the research will pave the way for a new class of drugs to help treat this devastating mental illness, which impacts one percent of the world's population, 30 percent of whom do not respond to currently available treatments. A team of researchers at Mount Sinai School of Medicine set out to discover what epigenetic factors, or external factors that influence gene expression, are involved in ...
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