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Annals of Internal Medicine tip sheet for June 21, 2011

2011-06-21
1. For Hypertension Patients, Single Reading Not Enough to Assess Blood Pressure Control Using Multiple Readings Increases Measurement Accuracy For patients with hypertension, physicians typically use a single in-office blood pressure (BP) reading to assess how well medical interventions are working and then adjust hypertension medications accordingly. However, some patients may experience a phenomenon known as "white coat" hypertension, meaning they have a higher than normal BP due to the anxiety associated with the office visit. Researchers sought to determine how ...

No injury spike in Bantam bodychecking

2011-06-21
A new study published in the Canadian Medical Association Journal by University of Calgary Faculty of Kinesiology researcher Dr. Carolyn Emery and colleagues has shown that when bodychecking is introduced into Bantam ice hockey there is no difference between overall injury rates or concussion, regardless of whether players have prior bodychecking experience in Pee Wee. Emery, co-chair of the Sport Injury Prevention Research Centre at the University of Calgary Sport Medicine Centre, began by comparing injury and concussion rates in Alberta where bodychecking is allowed, ...

Shorter pause in CPR before defibrillator use improves cardiac arrest survival

2011-06-21
A shorter pause in CPR just before a defibrillator delivered an electric shock to a cardiac arrest victim's heart significantly increased survival, according to a study in Circulation: Journal of the American Heart Association. Researchers found the odds of surviving until hospital discharge were significantly lower for patients whose rescuers paused CPR for 20 seconds or more before delivering a shock (the pre-shock pause), and for patients whose rescuers paused CPR before and after defibrillation (the peri-shock pause) for 40 seconds or more, compared to patients with ...

Latest Version of HairGenesis Hair Loss Product Formula, Published in New Peer Reviewed Medical Study

Latest Version of HairGenesis Hair Loss Product Formula, Published in New Peer Reviewed Medical Study
2011-06-21
In a landmark newly published study (http://www.hindawi.com/journals/ecam/2011/985345/), scientists from State University, New York working collaboratively with researchers from HairGenesis, report the positive outcome of a set of basic science experiments designed to test an advanced hair regrowth formula in a cell-based model of human hair follicle keratinocytes. Combining naturally derived 5 alpha-reductase inhibitors with highly potent anti-inflammatory agents, the scientific team showed how their proprietary composition could potentially outperform single agent hair ...

Acute Hepatitis A evades immune system more effectively than chronic cousin

2011-06-21
Chapel Hill, NC – Ongoing research into the problem of how Hepatitis C becomes a chronic disease has uncovered a deeper mystery about its sister strain, Hepatitis A. Hepatitis C is a continuing public health problem, which is difficult to measure because symptoms occur months to years after infection. The World Health Organization estimates as many as 2 to 4 million people in the United States may have chronic Hepatitis C, and most do not know they are infected. More than a third of those who are long-term carriers may develop chronic liver disease or liver cancer. "Hepatitis ...

Exercise training program improves outcomes in 'Grinch Syndrome' patients

2011-06-21
An exercise training program worked better than a commonly used beta blocker, significantly improving — even curing — patients with a debilitating heart syndrome, according to research published in Hypertension: Journal of the American Heart Association. Postural Orthostatic Tachycardia Syndrome (POTS) — called "The Grinch Syndrome" because most patients have a heart that's "two sizes too small" — affects about 500,000 Americans, primarily young women. POTS is characterized by a rapid increase in heartbeat of more than 30 beats per minute or a heart rate that exceeds ...

Millions with peripheral artery disease not getting vital medications

2011-06-21
Millions of adults with peripheral artery disease are not receiving the medications needed to reduce their risk of heart attack, stroke and death, according to research in Circulation: Journal of the American Heart Association. Most patients are not receiving recommended therapies such as cholesterol and blood pressure-lowering medications, the study's authors found. Peripheral artery disease is the result of atherosclerosis, or blockages in the arteries in the legs caused by plaque. People with this disease have a significantly increased risk of having either a non-fatal ...

Need a nap? Find yourself a hammock

2011-06-21
For grownups, drifting off for an afternoon snooze is often easier said than done. But many of us have probably experienced just how simple it can be to catch those zzz's in a gently rocking hammock. By examining brain waves in sleeping adults, researchers reporting in the June 21 issue of Current Biology, a Cell Press publication, now have evidence to explain why that is. The study finds that napping on a slowly swinging bed really does get us to sleep faster. To the researchers' surprise, rocking also changes the nature of our sleep, encouraging deeper sleep. "It ...

'Smart materials' that make proteins form crystals to boost research into new drugs

2011-06-21
Scientists have developed a new method to make proteins form crystals using 'smart materials' that remember the shape and characteristics of the molecule. The technique, reported today in Proceedings of the National Academy of Sciences, should assist research into new medicines by helping scientists work out the structure of drug targets. The process of developing a new drug normally works by identifying a protein that is involved in the disease, then designing a molecule that will interact with the protein to stimulate or block its function. In order to do this, scientists ...

Gay class tourism

2011-06-21
New research at the University of Leicester is investigating a growing fascination with 'chav' culture among middle-class gay men in Britain. Professor Joanna Brewis, from the University of Leicester School of Management, UK, will conduct primary empirical research into gay class tourism following publication of findings reported last year in the journal Sociology. Research she carried out with her former colleague Professor Gavin Jack, now at La Trobe University in Australia, revealed the complex consumer patterns of middle-class homosexual men who go 'slumming' at ...

Penn researchers link fastest sea-level rise in 2 millennia to increasing temperatures

2011-06-21
PHILADELPHIA — An international research team including University of Pennsylvania scientists has shown that the rate of sea-level rise along the U.S. Atlantic coast is greater now than at any time in the past 2,000 years and that there is a consistent link between changes in global mean surface temperature and sea level. The research was conducted by members of the Department of Earth and Environmental Science in Penn's School of Arts and Science: Benjamin Horton, associate professor and director of the Sea Level Research Laboratory, and postdoctoral fellow Andrew Kemp, ...

In colorectal surgery, risk for blood clots appears higher with open method versus laparoscopy

2011-06-21
The risk of developing venous thromboembolism (VTE) may be nearly twice as high for patients undergoing open surgery for colorectal problems, versus those undergoing laparoscopic colorectal (LC) resections, according to a report in the June issue of Archives of Surgery, one of the JAMA/Archives journals. Venous thromboembolism (the formation of blood clots in the veins) occurs in up to 25 percent of patients who undergo surgery without specific steps taken to prevent the condition, according to background information in the article. The authors note that colorectal surgery ...

In general, hospitals deliver appropriate surgical care to cancer patients with Medicare

2011-06-21
Most hospitals follow established practice guidelines for surgery involving Medicare beneficiaries with cancer, but in some cases their practice patterns diverge from the guidelines, according to a report published Online First today by Archives of Surgery, one of the JAMA/Archives journals. According to background information in the article, health care quality has emerged as an important concern in the United States. However, the right care is not always delivered to the right patient at the right time, the authors remark. "Currently, it is well documented that the ...

Analysis of studies evaluates tonsillectomy techniques

2011-06-21
A review of tonsillectomy-technique studies found that some new methods have advantages over traditional methods, but others are equivalent, according to a report in the June issue of Archives of Otolaryngology–Head and Neck Surgery, one of the JAMA/Archives journals. As background information, the article states that tonsillectomy is well established in terms of safety, but is often accompanied by pain, postsurgical bleeding, and a prolonged recovery. Traditionally, the operation has been performed using cold steel and/or electrocautery dissection (CS/EC). Newer methods ...

Intranasal corticosteroid treatment appears beneficial for children with obstructive sleep apnea

2011-06-21
Using a fluticasone furoate nasal spray for treatment of obstructive sleep apnea in children appears to reduce production of certain inflammatory cell proteins that may play a role in development of obstructive sleep apnea, according to a report in the June issue of Archives of Otolaryngology – Head & Neck Surgery, one of the JAMA/Archives journals. "Obstructive sleep apnea syndrome is characterized by prolonged partial upper airway obstruction and/or intermittent complete obstruction with disruption of normal ventilation during sleep and normal sleep patterns," the authors ...

Study compares 2 types of botulinum toxin for cosmetic use

2011-06-21
Not all varieties of botulinum toxin seem to be equally effective in reducing crow's feet wrinkles, according to a report published Online First today by Archives of Facial Plastic Surgery, one of the JAMA/Archives journals. Botulinum toxin, a protein long considered harmful, is now known as a neuromodulator (a chemical that affects nerve impulses) that has cosmetic and medical uses, according to background information in the article. In 1989, botulinum toxin type A was approved in the United States for two muscular conditions that affect the appearance of the eyes. In ...

Salt marsh sediments help gauge climate-change-induced sea level rise

2011-06-21
A newly constructed, 2,000-year history of sea level elevations will help scientists refine the models used to predict climate-change-induced sea level rise, according to an international team of climate researchers. The record also shows that the past century had the fastest recorded rate of sea level rise. "One of the largest uncertainties in projecting the impacts of climate change involve predicting the amount and rate of future sea level rise," said Michael E. Mann, professor of meteorology, Penn State. "The societal ramifications are as great as any climate change ...

Nanoparticles disguised as red blood cells will deliver cancer-fighting drugs

2011-06-21
Researchers at the University of California, San Diego have developed a novel method of disguising nanoparticles as red blood cells, which will enable them to evade the body's immune system and deliver cancer-fighting drugs straight to a tumor. Their research will be published next week in the online Early Edition of the Proceedings of the National Academy of Sciences. The method involves collecting the membrane from a red blood cell and wrapping it like a powerful camouflaging cloak around a biodegradable polymer nanoparticle stuffed with a cocktail of small molecule ...

New study reveals how the immune system responds to hepatitis A virus

2011-06-21
A surprising finding in a study comparing hepatitis C virus (HCV) with hepatitis A virus (HAV) infections in chimpanzees by a team that includes scientists from the Texas Biomedical Research Institute sheds new light on the nature of the body's immune response to these viruses. Understanding how hepatitis C becomes chronic is very important because some 200 million people worldwide and 3.2 million people in the U.S. are chronically infected with HCV and are at risk for progression to cirrhosis and liver cancer. Hepatitis C associated liver disease is the most common ...

Adulterated cocaine causing serious skin reactions

Adulterated cocaine causing serious skin reactions
2011-06-21
LOS ANGELES—(June 20, 2011)—Doctors warned of a potential public health epidemic in a recent report on patients in Los Angeles and New York who developed serious skin reactions after smoking or snorting cocaine believed to be contaminated with a veterinary medication drug dealers are using to dilute, or "cut," up to 70% of the cocaine in the U.S. The report, published online in the Journal of the American Academy of Dermatology, said six patients developed purple-colored patches of necrotic skin on their ears, nose, cheeks and other parts of their body and, in some instances, ...

Australian Sun Protective Wear Now Available in the U.S.

Australian Sun Protective Wear Now Available in the U.S.
2011-06-21
Solartex Sun Gear, Inc., a leader in sun protective clothing in the United States, is introducing its newest line that provides the maximum (50+) SPF/UPF in sun protection. Designed in Australia, these colorful rash shirts, swimsuits and hats come in a full range of sizes from 0 to 8xl, offering something for everyone from the newborn to the plus-sized adult. Since its founding in 1998, Solartex has specialized in locating, importing, manufacturing, and retailing sun protective UV clothing to U.S. and international consumers. It is now designing and manufacturing private ...

3 postulates to help identify the cause of Alzheimer's disease

2011-06-21
Amsterdam, The Netherlands, June 20, 2011 -- After more than 100 years following its pathologic description, the cause of Alzheimer's disease (AD) remains unknown. To test the validity of present and future proposals related to the probable cause of AD, three postulates, or necessary conditions, are recommended by Jack de la Torre, MD, PhD, Adjunct Professor of Psychology at the University of Texas, Austin, in an article published in the Journal of Alzheimer's Disease. "Knowing what causes AD is critically important because it would allow more effective therapy to specifically ...

Unexpected function of dyslexia gene

2011-06-21
Scientists at Karolinska Institutet in Sweden have discovered that a gene linked to dyslexia has a surprising biological function: it controls cilia, the antenna-like projections that cells use to communicate. Dyslexia is largely hereditary and linked to a number of genes, the functions of which are, however, largely unknown. This present study from Karolinska Institutet and Helsinki University now shows that one of these genes, DCDC2, is involved in regulating the signalling of cilia in brain neurons. "Our discovery presents us with a possible new neurobiological ...

Research reveals that 10 percent of middle-aged Europeans are on antidepressants

Research reveals that 10 percent of middle-aged Europeans are on antidepressants
2011-06-21
New research from the University of Warwick and the IZA Institute in Bonn shows that 10% of middle-aged Europeans took antidepressants in 2010. The researchers looked in detail at the lives of a randomly selected sample of nearly 30,000 Europeans. The study covered 27 countries. Andrew Oswald, an economics professor at the University of Warwick, and co-author of the study, described the results as concerning, he said: "Antidepressants are a relatively new kind of commodity. We are only starting to get proper data on who takes them. But as we live in the richest and safest ...

Let your fingers do the talking: Sexting and infidelity in cyberspace

2011-06-21
Although sex and infidelity are now only a keyboard away, at the end of the day, there is no substitute for physical, face-to-face contact in our sexual relationships. That's according to a new study by Diane Kholos Wysocki, from the University of Nebraska at Kearney, and Cheryl Childers, from Washburn University in Topeka, Kansas. They investigated the behaviors of infidelity on the internet and sexting - sending sexually explicit text messages and photographs via email or cell phone. Their findings are published online in Springer's journal, Sexuality & Culture. The ...
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