University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries. The new machine-learning tool has already found a promising candidate to help prevent harmful heart scarring in a way distinct from previous drugs. The UVA researchers say their cutting-edge computer model has the potential to predict and explain the effects of drugs for other diseases as well. “Many common diseases such as heart disease, ...

A large multicenter clinical trial co-led by University of Maryland School of Medicine researchers large multicenter clinical trial co-led by University of Maryland School of Medicine researchers found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic. The results of the study of nearly 8,500 patients across the United States and Canada were published today in the New England Journal of Medicine. The study – which compared the ...

We may not always fully understand why our partners get jealous, and women and men often get jealous for completely different reasons. Two researchers from the Norwegian University of Science and Technology (NTNU) decided to investigate whether people also know about these distinct differences between the sexes. “What do people think triggers women’s and men’s jealousy? How well do women understand men’s jealousy, and men women’s jealousy? We wanted to find out,” says Professor Mons Bendixen at the Department of Psychology. Men are more jealous ...

WASHINGTON — Both liberals and conservatives are more likely to believe that merit-based hiring is unfair after learning about the impacts of socioeconomic disparities, according to a study published by the American Psychological Association. People from across the political spectrum also are more likely to support programs that encourage socioeconomic diversity after learning about the effects of social class and low income, according to the research, published online in the Journal of Experimental Psychology: General. “Socioeconomic disadvantages early in life can undermine educational achievement, ...

Excavation workers have finished carving out the future home of the gigantic particle detectors for the international Deep Underground Neutrino Experiment. Located a mile below the surface, the three colossal caverns are at the core of a new research facility that spans an underground area about the size of eight soccer fields. Hosted by the U.S. Department of Energy’s Fermi National Accelerator Laboratory, DUNE scientists will study the behavior of mysterious particles known as neutrinos to solve some of the biggest questions about our universe. Why is our ...

Black, indigenous, and people of color (BIPOC) who were infected with COVID-19 experienced greater negative aftereffects in health and work loss than did similarly infected white participants, new research finds.   Despite similar symptom prevalence, BIPOC and Hispanic patients experienced greater negative impacts on their health status, activity levels, and ability to work compared with non-Hispanic and white patients participating in the ongoing multi-site INSPIRE clinical trial examining people with long COVID.   The findings are published in the journal Frontiers ...

ROCKVILLE, Md. — A member of the National Academy of Medicine is the new president of The Obesity Society (TOS), the organization announced today.  Jamy Ard, MD, FTOS, is professor in the Departments of Epidemiology and Prevention and Internal Medicine and vice dean of Clinical Research at Wake Forest University School of Medicine in Winston-Salem, N.C. He also co-directs the Atrium Health Wake Forest Baptist Weight Management Center, where he oversees medical weight management programs. “I am honored to serve as president of ...

Updating passwords for all users of a company or institution’s internal computer systems is stressful and disruptive to both users and IT professionals. Many studies have looked at user struggles and password best practices. But very little research has been done to determine how a password update campaign can be conducted most efficiently and with minimal IT costs. Until now.  A team of computer scientists at the University of California San Diego partnered with the campus’ Information Technology Services to analyze the messaging for a campuswide mandatory ...

Chocolate valentines and candies with sweet sayings shouldn't be the only hearts you think about this February. It’s also American Heart Month, which puts a spotlight on cardiovascular health. According to the American Heart Association, heart disease is the leading cause of death for Americans, so it’s important to know the status of your own heart health. New methods for cardiac monitoring can be found in these five papers recently published in ACS journals. Reporters can request free access to these papers by emailing newsroom@acs.org. Future ...

The intricate relationship that exists between humans and the gut microbiome has become a hot research topic, and scientists are constantly uncovering new reasons why a healthy diet can lead to a healthier life. Dietary fibers are a particularly important aspect of this connection. When we ingest these compounds, which are mainly found in plant-based foods, our gut bacteria break them down into small molecules, called short-chain fatty acids (SCFAs). Over the past few years, studies have revealed various important anti-inflammatory and immunomodulating effects of SCFAs. One of the ways SCFAs interact with ...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset. This disease causes weakness and atrophy of limbs and other muscles, which affect mobility speech, eating, and even breathing in patients. Some drugs, including riluzole, edaravone, and sodium phenylbutyrate/taurursodiol are used for treating ALS, but with limited therapeutic benefits. Therefore, novel, effective ALS treatments are the need of the hour.  Multilineage-differentiating stress-enduring (Muse) cells are pluripotent stem cells ...

Researchers from Chalmers University of Technology, in Sweden, have discovered a change in what scientists already knew about global warming dynamics. It had been widely accepted since the 1950s that global temperature rises were not consistent throughout the day and night, with greater nighttime warming being observed. However, the recent study reveals a shift in dynamics: with greater daytime warming taking place since the 1990s. This shift means that the temperature difference between day and night is widening, potentially affecting all life on Earth.   The ...

HOUSTON – (Feb. 1, 2024) – A team of Rice University researchers mapped out how flecks of 2D materials move in liquid ⎯ knowledge that could help scientists assemble macroscopic-scale materials with the same useful properties as their 2D counterparts. “Two-dimensional nanomaterials are extremely thin ⎯ only several atoms thick ⎯ sheet-shaped materials,” said Utana Umezaki, a Rice graduate student who is a lead author on a study published in ACS Nano. “They behave very differently from materials we’re used to in daily life and can have really useful properties: They can withstand a lot of ...

Previous studies have found less than 40% of patients with stable chest pain undergoing invasive coronary angiography are found to have obstructive coronary artery disease. Recent randomized clinical trials have demonstrated a benefit to using computed tomography angiography (CTA) first in evaluation of these patients, and a new study being presented at the American College of Cardiology Cardiovascular Summit lends credence to this strategy, finding that CT was associated with a higher likelihood of revascularization compared to other imaging modalities or no testing. Stable angina ...

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The research also introduced a novel treatment and a method to track effective treatment interventions. The research was published online in Brain, Behavior & Immunity.   Dr. Selin, professor of pathology, ...

Research Highlights: Black women who develop high blood pressure before age 35 may have triple the odds of having a stroke, and those who develop high blood pressure before age 45 may have twice the risk of suffering a subsequent stroke. The findings, from a study of 59,000 Black women in the U.S., are important for expanding high blood pressure screening and treatment in this high-risk population. Researchers say health care professionals should be vigilant in high blood pressure screening and ...

Research Highlights: One month after hospital evaluation for stroke-like symptoms, people whose symptoms were attributed to another condition were 3 times more likely to have increased risk of post-traumatic stress disorder (PTSD) than people diagnosed with a confirmed stroke. Knowing that the experience of being evaluated for stroke can itself be traumatic may help health care professionals recognize PTSD symptoms and connect people quickly to the appropriate resources. Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, Feb. 1, 2024 DALLAS, Feb. 1, 2024 — People with so-called stroke mimics may be even more likely to develop post-traumatic stress ...

Research Highlights: Lifetime exposure to different types of traumatic events or stress appears to reduce the chances for optimal recovery after a stroke. A review of health records for U.S. stroke survivors found that sexual assault was consistently linked to worse physical functioning and poorer cognitive recovery measurements one year after a stroke. Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, Feb. 1, 2024 DALLAS, Feb. 1, 2024 — Stressors and traumatic events experienced over the course of a lifetime may negatively impact subsequent stroke recovery; specifically, stroke survivors exposed to sexual assault at any point in their life had  poorer physical functioning ...

Research Highlights: In a large population study conducted in Canada, the risk of dementia was nearly 3 times higher in the first year after a stroke, then fell to a 1.5-times increased risk by the 5-year mark and remained elevated 20 years later. Having a stroke increased the risk of dementia by 80%, even after accounting for other dementia risk factors, such as high blood pressure, Type 1 or Type 2 diabetes and high cholesterol. Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, Feb. 1, 2024 DALLAS, Feb. 1, 2024 — Having a stroke may significantly increase the risk of developing dementia. ...

Research Highlights: Stimulating a nerve that runs between various organs and the brain with intense physical rehabilitation improved arm and hand function in people with stroke. The improved motor function remained at the end of the one-year follow-up. Vagus nerve stimulation uses an implantable device to stimulate the nerve with electrical impulses that help create new pathways in the brain to assist movement in impaired limbs. Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, Feb. 1, 2024 DALLAS, Feb. 1, 2024 — Combining brain ...

Research Highlights: Stroke survivors living in areas with high levels of unemployment, low income, low education levels and poor housing quality had twice the risk of poor recovery after a stroke compared to those living in areas with better conditions. The researchers say this study may help promote awareness of how social determinants of health are as important as clinical variables and health information when trying to identify stroke survivors who are at particularly high risk for poor long-term outcomes. Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, Feb. 1, 2024 DALLAS, Feb. 1, 2024 — Stroke survivors living in areas with ...

Research Highlights: Compared with the standard medication alteplase, the newer clot-busting medication tenecteplase may offer a safe, effective and simpler way to treat clot-caused stroke in special ambulances called mobile stroke units. Tenecteplase is given in a simpler, single injection into the bloodstream, while alteplase requires an hour-long infusion after an initial injection. The study reviewed the real-world experiences of a single mobile stroke unit in Phoenix between February 2021 and April 2023. Embargoed until 4 a.m. CT/5 a.m. ET, Thursday, ...

Research Highlights: The risk of a heart attack among adults after a clot-caused stroke or a stroke plus a tear in the wall of a neck artery (carotid or vertebral artery dissection) was almost double within the first year compared to the heart attack risk for people who did not have a stroke but were hospitalized with medical events. The medical events included some overlapping symptoms, such as “warning stroke,” migraine or transient global amnesia. However, people with a carotid artery or vertebral artery dissection but no stroke were not significantly more likely to have a heart attack than those with a warning stroke, migraine or amnesia. Embargoed until ...

Research Highlights: Among most ischemic (clot-caused) stroke survivors including those taking anticoagulant medications, use of antidepressants in the SSRI or SNRI class did not increase the risk of hemorrhagic (bleeds) stroke or other serious bleeding events. However, patients taking anti-depressants in combination with dual anti-platelet therapy or DAPT had an increased risk of bleeding. In addition, antidepressants from other classes increased the risk of serious bleeding events by 15% in comparison to antidepressants in the SSRI or SNRI classes. Embargoed until 4 a.m. CT/5 a.m. ET, ...

Research Highlights: In a study conducted in China, adults treated with 14 days of intravenous injections of ginkgo diterpene lactone meglumine (GDLM) — a combination of biologically active components of ginkgo biloba — after an ischemic (clot-caused) stroke had better cognitive recovery at 14 days and 90 days. IV preparations of ginkgo biloba’s active ingredients are widely used in China as a complementary treatment for ischemic stroke. While oral ginkgo biloba supplements are widely available and marketed in the U.S., gingko biloba is not approved for medicinal use by the U.S. Food and Drug Administration. Embargoed ...