STANFORD, Calif. — Neurons have been derived from the skin of a woman with a genetic form of Parkinson's disease and have been shown to replicate some key features of the condition in a dish, say researchers at the Stanford University School of Medicine. The scientists hope to use the neurons to learn more about the disorder and to test possible treatments. Such a tool is critical because there are no good animal models for Parkinson's disease. It also validates the use of induced pluripotent stem cells, or iPS cells, to model various diseases. "Now that we can see that ...

STANFORD, Calif. — A short-term treatment with three immune-dampening drugs allowed human embryonic stem cells to survive and thrive in mice, according to researchers at the Stanford University School of Medicine. Without such treatment, the animals' immune systems quickly hunt down and destroy the transplanted cells. The finding is important because it may allow humans to accept transplanted stem cells intended to treat disease or injury without requiring the ongoing use of powerful immunosuppressant medications. Just as it does with transplanted organs, the human body ...

Plants are able to protect themselves from most bacteria, but some bacteria are able to breach their defences. In research to be published in Science on Friday, scientists have identified the genes used by some strains of the bacterium Pseudomonas to overwhelm defensive natural products produced by plants of the mustard family, or crucifers. "Microbes only become pathogens when they find a way to infect a host and overwhelm the host defences," said lead author Dr Jun Fan from the John Innes Centre on the Norwich Research Park. "Our findings answer some important questions ...

PULLMAN, Wash.—Scientific societies representing 40,000 researchers and clinicians are asking that federal regulators tap a broader range of expertise when evaluating the risks of chemicals to which Americans are being increasingly exposed. Writing in a letter in the journal Science, eight societies from the fields of genetics, reproductive medicine, endocrinology, developmental biology and others note that some 12,000 new substances are being registered with the American Chemical Society daily. Few make it into the environment, but the top federal regulators, the U.S. ...

Scientists working in the remotest part of Antarctica have discovered that liquid water locked deep under the continent's coat of ice regularly thaws and refreezes to the bottom, creating as much as half the thickness of the ice in places, and actively modifying its structure. The finding, which turns common perceptions of glacial formation upside down, could reshape scientists' understanding of how the ice sheet expands and moves, and how it might react to warming climate, they say. The study appears in this week's early online edition of the leading journal Science; ...

Irvine, Calif. — A UC Irvine research team led by Todd C. Holmes has discovered a second form of phototransduction light sensing in cells that is derived from vitamin B2. This discovery may reveal new information about cellular processes controlled by light. For more than 100 years, it had been believed that the phototransduction process was solely based on a chemical derived from vitamin A called retinal. Phototransduction is the conversion of light signals into electrical signals in photoreceptive neurons and underlies both image-forming and non-image-forming light ...

Fraser Yachts is delighted to announce the addition of five new vessels to their ever expanding list of luxury yachts for sale. Built in 1967 and refurbished in 2005, the largest of the new collection is M/Y Il Odyssey yacht. Hailing from the Benetti Yachts shipyard, the Il Odyssey luxury yacht is 37.8m in length and can sleep 9 guests and 6 crew members. She is currently on sale in Monaco for EUR1,950,000. One of the youngest luxury yachts for sale is M/Y Team VIP yacht. Built in 2010, and built by Guy Couach, this mega yacht is the newest of its siblings of four. ...

COLLEGE PARK, Md. – When it comes to the federal budget, the public is on a different page than either the House of Representatives or the Obama Administration – with a different set of priorities and a greater willingness to cut spending and increase taxes – concludes a new analysis by the University of Maryland's Program for Public Consultation (PPC). This new analysis compares the House and administration budget proposals with those produced by a representative sample of U.S. adults. These public budgets were part of an innovative study released last month. While ...

Astronomy & Astrophysics publishes new high angular resolution observations of the giant planet orbiting the star beta Pictoris. Located at 63.4 light-years from the Sun, beta Pic is a very young star of about 12 million years old [1], which is 75% more massive than our Sun. beta Pic is well known for harboring an extended and structured circumstellar disk. It was actually the first star to have its disk directly imaged more than 25 years ago. In 2009, a giant planet was seen orbiting within the disk. With an orbital distance of 8 to 15 astronomical units (AU), beta Pictoris ...

A research team from the University of Valencia has discovered that up to 20% of spices and 26% of herbs sold in Spain are contaminated by various bacteria, reducing their quality. The study, which is the first of its kind in Spain, suggests that health and hygiene control systems should be put in place, from cultivation of these products right through to when they reach the market. Scientists from the University of Valencia have for the first time studied the microbiological quality of 53 samples of spices and herbs such as thyme and oregano sold at Spanish markets. The ...

New research into the neurodegenerative disease, Multiple Sclerosis (MS) offers new insight into the link between sunlight, vitamin D3, and MS risk and severity. The research, published in the European Journal of Immunology, studies the relationship between the sunlight-dependent vitamin D3 hormone, immune cells, and the risk and severity of autoimmunity in an experimental model. Expensive first-line treatments for MS modestly reduce the frequency of autoimmune attacks but do not slow disease progression, when the patient's immune system operates against the body's own ...

All night long, bats swoop over our landscape consuming insects, but they do this in secret, hidden from our view. Until recently, scientists have been unable to bring their ecosystem out of the dark but thanks to new genetic techniques, researchers from the University of Bristol and Biodiversity Institute of Ontario, Canada, have been able to reconstruct the environment supporting these elusive creatures. Working at three sites in Southern Ontario (Canada) the team of students and scientists monitored the diet of little brown bats (Myotis lucifugus) from colonies living ...

Each of these luxury yachts measures between 24m and 30m and are able to accommodate at least 8 overnight guests. Far more manoeuvrable and economic these smaller yachts are no less desirable on a luxury yacht charter. The sailing yacht Rafoly (28.2m) is one the most advanced sailing catamarans available. Launched in 2008 from the Yachts Industries shipyard in Caen, France, she is simple to sail yet gives a feeling of speed similar to that of a performance sailing yacht. Rafoly is able to accommodate 8 overnight guests in her four large cabins, and thanks to her spacious ...

A novel study from the Swedish medical university Karolinska Institutet has deepened the understanding of how chromosome replication, one of life's most fundamental processes, works. In a long term perspective these results could eventually lead to novel cancer therapies. The study is presented in the prestigious scientific journal Nature. By studying DNA replication in yeast cells, researchers at Karolinska Institutet have discovered that a protein complex (Smc5/6) helps to release torsional stress created in the DNA molecule when chromosomes are replicated in preparation ...

More than 15,000 adults of working age took part in the survey for Understanding Society, the world largest household panel study funded by the Economic and Social Research Council and run by the Institute of Social and Economic Research (ISER) at the University of Essex. The survey which will follow 40,000 UK households over many years, asks people about a wide range of topics including their employment status, families, income levels and well-being. It found that people's employment status during the recession had a major impact on how they coped financially. Forty ...

How well our brain functions is largely based on our family's genetic makeup, according to a University of Melbourne led study. The study published in the international publication the Journal of Neuroscience provides the first evidence of a genetic effect on how 'cost-efficient' our brain network wiring is, shedding light on some of the brain's make up. Lead author Dr Alex Fornito from the Melbourne Neuropsychiatry Centre at the University of Melbourne, Australia said the findings have important implications for understanding why some people are better able to perform ...

DURHAM, N.H. – People who feel more secure in receiving love and acceptance from others place less monetary value on their possessions, according to new research from the University of New Hampshire. The research was conducted by Edward Lemay, assistant professor of psychology at UNH, and colleagues at Yale University. The research is presented in the Journal of Experimental Social Psychology in the article "Heightened interpersonal security diminishes the monetary value of possessions." Lemay and his colleagues found that people who had heightened feelings of interpersonal ...

According to a study conducted at the Department of Pedagogy of the University of Granada, about six out of ten male drug-abusers direct some type of violence against their intimate partners. Thus, the study revealed a high rate of domestic violence –both pysical and psychological– by male drug-abusers against women. The study also detailed the most recurrent forms of abuse, as well as the variables associated to them. The study revealed that between 6.5 and 72.4% of the population admits to having committed some form of violence against their partner. The less prevalent ...

Washington, DC, March 3, 2011 – Community gym surfaces do not appear to be reservoirs for MRSA transmission, according to a study published in the March issue of the American Journal of Infection Control, the official publication of APIC – the Association for Professionals in Infection Control and Epidemiology. The purpose of the study, conducted by researchers from the University of Florida College of Medicine, was to determine whether community gymnasium equipment surfaces could harbor staphylococcal colonies and to assess whether disinfection lowers the rate of bacterial ...

Researchers at Queen's University Belfast are taking the first step towards discovering the true effectiveness of brain training exercises with the release of their own app aimed at those over 50. The Brain Jog application is available to download free for iPhone, iPod or iPad. It is the product of 18 months of work by researchers at Queen's School of Music and Sonic Arts to find out what the over 50's are looking for in a brain training app. Queen's researchers are encouraging as many people as possible to download and use the application. During the process, users ...

Researchers determined that carotid artery stenting (CAS) with embolic protection is an economically attractive alternative to endarterectomy (END) for patients at increased surgical risk. The study, based on data from the Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) trial, found that initial procedural cost was higher with CAS, but post-procedure hospital stay was shorter which significantly offset associated costs compared to END. Details of the study—the first to evaluate the long-term cost-effectiveness of CAS versus ...

BLOOMINGTON, Ind. -- As carbon dioxide levels have risen during the last 150 years, the density of pores that allow plants to breathe has dwindled by 34 percent, restricting the amount of water vapor the plants release to the atmosphere, report scientists from Indiana University Bloomington and Utrecht University in the Netherlands in an upcoming issue of the Proceedings of the National Academy of Sciences (now online). In a separate paper, also to be published by PNAS, many of the same scientists describe a model they devised that predicts doubling today's carbon dioxide ...

Our earliest ancestors preferred to settle in locations that have something in common with cities such as San Francisco, Naples and Istanbul -- they are often on active tectonic faults in areas that have an earthquake risk or volcanoes, or both. An international team of scientists has established a link between the shape of the landscape and the habitats preferred by our earliest ancestors. The research, by scientists at the University of the Witwatersrand, South Africa, the University of York and the Institut de Physique du Globe Paris (IPGP), is published in the ...

Microsoft SharePoint experts have joined forces at www.sharepoint-blog.com to provide reviews, comparisons and opinions to assist clients in selecting the right collaboration software. Group blog sites combine resources of firms to create active blog sites that build trust, get attention and attract visitors. Following the model of successful group blog sites for Microsoft Dynamics Partners including www.erpsoftwareblog.com and www.crmsoftwareblog.com this blog site will provide objective articles from Microsoft SharePoint experts nationwide. Rather than being focused ...

People in marginalized groups, such as the disabled or racial minorities, feel stigmatized—condemned, feared, or excluded—when other people stigmatize them. That's obvious. But they can also feel stigma when nobody blatantly discriminates against them or says a negative word. These folks aren't paranoid, suggests a new study of HIV-positive people and their communities to be published in Psychological Science, a journal of the Association of Psychological Science. Rather, they're picking up subtle clues from their communities. "Society is changing when it comes to ...